EG22630A - Process for preparation of pyrazoleo (4,3-D) pyrimidin-7-ones and intermediates thereof - Google Patents

Process for preparation of pyrazoleo (4,3-D) pyrimidin-7-ones and intermediates thereof

Info

Publication number: EG22630A
Authority: EG; Egypt
Prior art keywords: pyrazoleo; pyrimidin; intermediates; ones; preparation
Prior art date: 1998-10-12

Application number

EG126999A

Other languages

English (en)

Original Assignee

Pfizer Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-12

Filing date

1999-10-11

Publication date

2003-05-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10840421&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG22630(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-10-11 Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev

2003-05-31 Application granted granted Critical

2003-05-31 Publication of EG22630A publication Critical patent/EG22630A/xx

Links

239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Reproductive Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Gynecology & Obstetrics (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EG126999A 1998-10-12 1999-10-11 Process for preparation of pyrazoleo (4,3-D) pyrimidin-7-ones and intermediates thereof EG22630A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9822238.3A GB9822238D0 (en)	1998-10-12	1998-10-12	Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof

Publications (1)

Publication Number	Publication Date
EG22630A true EG22630A (en)	2003-05-31

Family

ID=10840421

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG126999A EG22630A (en)	1998-10-12	1999-10-11	Process for preparation of pyrazoleo (4,3-D) pyrimidin-7-ones and intermediates thereof

Country Status (48)

Country	Link
US (3)	US6207829B1 (fr)
EP (1)	EP0994115B1 (fr)
JP (1)	JP3721021B2 (fr)
KR (1)	KR100380954B1 (fr)
CN (2)	CN1207295C (fr)
AP (1)	AP1233A (fr)
AR (1)	AR019244A1 (fr)
AT (1)	ATE290003T1 (fr)
AU (1)	AU756463B2 (fr)
BG (1)	BG63205B1 (fr)
BR (1)	BR9905092A (fr)
CA (1)	CA2285733C (fr)
CO (1)	CO5150214A1 (fr)
CR (1)	CR6118A (fr)
CU (1)	CU22928A3 (fr)
CZ (1)	CZ296816B6 (fr)
DE (1)	DE69923906T2 (fr)
DK (1)	DK0994115T3 (fr)
DZ (1)	DZ2912A1 (fr)
EA (1)	EA003774B1 (fr)
EE (1)	EE04192B1 (fr)
EG (1)	EG22630A (fr)
ES (1)	ES2237049T3 (fr)
GB (1)	GB9822238D0 (fr)
GE (1)	GEP20022700B (fr)
GT (1)	GT199900172A (fr)
HR (1)	HRP990318B1 (fr)
HU (1)	HU226162B1 (fr)
ID (1)	ID23351A (fr)
IL (11)	IL152928A (fr)
IS (1)	IS1951B (fr)
MA (1)	MA25007A1 (fr)
MY (1)	MY124620A (fr)
NO (1)	NO313700B1 (fr)
OA (1)	OA11165A (fr)
PE (1)	PE20001086A1 (fr)
PL (1)	PL198150B1 (fr)
PT (1)	PT994115E (fr)
RS (1)	RS49762B (fr)
SG (1)	SG118060A1 (fr)
SI (1)	SI0994115T1 (fr)
SK (1)	SK285215B6 (fr)
TN (1)	TNSN99189A1 (fr)
TR (1)	TR199902541A2 (fr)
TW (1)	TW589314B (fr)
UA (1)	UA66787C2 (fr)
UY (1)	UY25750A1 (fr)
ZA (1)	ZA996412B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000078760A1 (fr) *	1999-06-21	2000-12-28	The Biochemical Pharmaceutical Factory Of Zhuhai Sez	Procede de preparation de sildenafil, agent et procede d'obtention d'un comprime mixte a base de sildenafil et de chlorhydrate d'apomorphine
US6667398B2 (en)	2000-06-22	2003-12-23	Pfizer Inc	Process for the preparation of pyrazolopyrimidinones
YU93902A (sh) *	2000-06-22	2005-11-28	Pfizer Products Inc.	Postupak za pripremanje pirazolopirimidinona
EP1176142A1 (fr) *	2000-07-28	2002-01-30	Pfizer Inc.	Procédé pour la préparation de pyrazoles
US6407259B1 (en)	2000-07-28	2002-06-18	Pfizer Inc.	Process for the preparation of pyrazoles
YU51701A (sh) *	2000-07-28	2003-12-31	Pfizer Inc.	Postupak za dobijanje jedinjenja pirazola/4,3-d/ pirimidin-7-ona i njihovih derivata
PE20020394A1 (es)	2000-08-18	2002-06-21	Agouron Pharma	Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2
AU2002358772B2 (en)	2001-12-20	2008-11-20	Merck Serono Sa	Pyrrolidine derivatives as prostaglandin modulators
CA2470427C (fr) *	2001-12-21	2012-07-10	Cytokinetics, Incorporated	Compositions et methodes permettant de traiter l'insuffisance cardiaque
SI1509525T1 (sl)	2002-05-31	2006-12-31	Schering Corp	Postopek priprave inhibitorjev ksantinske fosfodiesteraze V in njihovih prekurzorjev
WO2004072079A1 (fr) *	2003-02-11	2004-08-26	Pfizer Limited	Compose d'hemi-citrate de sildenafil hydrate et anhydre
WO2004086865A1 (fr) *	2003-03-27	2004-10-14	Cytokinetics, Inc.	Composes, compositions et methodes
CN100360531C (zh) *	2003-12-18	2008-01-09	中国人民解放军军事医学科学院放射与辐射医学研究所	用于预防或治疗阳萎和性冷淡的新吡唑并嘧啶类化合物
US20070010525A1 (en) *	2005-06-27	2007-01-11	Meyer Jackson	Method and compositions for modulating neuropeptide hormone secretion
NL2000291C2 (nl) *	2005-11-10	2009-02-17	Pfizer Prod Inc	1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
EP2024369A4 (fr) *	2006-06-05	2010-10-27	Matrix Lab Ltd	Nouveau procédé de préparation du citrate de sildénafil
CZ308056B6 (cs) *	2015-07-20	2019-11-27	Ustav Experimentalni Botaniky Av Cr V V I	5-Substituované-7-[4-(substituované)benzyl]amino-3-isopropylpyrazolo[4,3-d]pyrimidiny, jejich použití jako antirevmatika, a farmaceutické přípravky
WO2017168174A1 (fr)	2016-04-02	2017-10-05	N4 Pharma Uk Limited	Nouvelles formes pharmaceutiques du sildénafil
CN107759603B (zh) *	2016-08-18	2020-09-01	四川科伦药物研究院有限公司	一种杂环化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3992441A (en) *	1972-12-26	1976-11-16	Pfizer Inc.	Sulfamylbenzoic acids
GB9013750D0 (en) *	1990-06-20	1990-08-08	Pfizer Ltd	Therapeutic agents
GB9612514D0 (en) *	1996-06-14	1996-08-14	Pfizer Ltd	Novel process
CA2288910C (fr) *	1997-04-25	2003-06-24	Pfizer Inc.	Pyrazolopyrimidinones pour des dysfonctions sexuelles

1998
- 1998-10-12 GB GBGB9822238.3A patent/GB9822238D0/en not_active Ceased
1999
- 1999-09-22 TW TW088116306A patent/TW589314B/zh not_active IP Right Cessation
- 1999-09-22 CU CU1999142A patent/CU22928A3/es unknown
- 1999-09-27 RS YUP-489/99A patent/RS49762B/sr unknown
- 1999-10-05 GT GT199900172A patent/GT199900172A/es unknown
- 1999-10-06 CZ CZ0353299A patent/CZ296816B6/cs not_active IP Right Cessation
- 1999-10-07 IL IL152928A patent/IL152928A/en not_active IP Right Cessation
- 1999-10-07 CR CR6118A patent/CR6118A/es unknown
- 1999-10-07 AP APAP/P/1999/001672A patent/AP1233A/en active
- 1999-10-07 IL IL15292499A patent/IL152924A/en not_active IP Right Cessation
- 1999-10-07 IL IL15292399A patent/IL152923A/en not_active IP Right Cessation
- 1999-10-07 IL IL13227399A patent/IL132273A/en not_active IP Right Cessation
- 1999-10-07 IL IL15292699A patent/IL152926A/en not_active IP Right Cessation
- 1999-10-07 PE PE1999001016A patent/PE20001086A1/es not_active Application Discontinuation
- 1999-10-07 IL IL15292799A patent/IL152927A/en not_active IP Right Cessation
- 1999-10-08 UA UA99105491A patent/UA66787C2/xx unknown
- 1999-10-08 OA OA9900224A patent/OA11165A/en unknown
- 1999-10-08 US US09/415,440 patent/US6207829B1/en not_active Expired - Fee Related
- 1999-10-08 AR ARP990105109A patent/AR019244A1/es active IP Right Grant
- 1999-10-08 IS IS5209A patent/IS1951B/is unknown
- 1999-10-08 MY MYPI99004353A patent/MY124620A/en unknown
- 1999-10-08 CA CA002285733A patent/CA2285733C/fr not_active Expired - Lifetime
- 1999-10-08 SK SK1385-99A patent/SK285215B6/sk not_active IP Right Cessation
- 1999-10-09 CN CNB991239180A patent/CN1207295C/zh not_active Expired - Fee Related
- 1999-10-09 CN CNA031427383A patent/CN1473831A/zh active Pending
- 1999-10-11 AU AU53581/99A patent/AU756463B2/en not_active Ceased
- 1999-10-11 DE DE69923906T patent/DE69923906T2/de not_active Expired - Lifetime
- 1999-10-11 PT PT99307996T patent/PT994115E/pt unknown
- 1999-10-11 DZ DZ990212A patent/DZ2912A1/fr active
- 1999-10-11 ES ES99307996T patent/ES2237049T3/es not_active Expired - Lifetime
- 1999-10-11 TN TNTNSN99189A patent/TNSN99189A1/fr unknown
- 1999-10-11 SI SI9930773T patent/SI0994115T1/xx unknown
- 1999-10-11 ZA ZA9906412A patent/ZA996412B/xx unknown
- 1999-10-11 BR BR9905092-7A patent/BR9905092A/pt not_active IP Right Cessation
- 1999-10-11 EA EA199900822A patent/EA003774B1/ru not_active IP Right Cessation
- 1999-10-11 KR KR10-1999-0043836A patent/KR100380954B1/ko not_active Expired - Fee Related
- 1999-10-11 HU HU9903469A patent/HU226162B1/hu not_active IP Right Cessation
- 1999-10-11 NO NO19994943A patent/NO313700B1/no not_active IP Right Cessation
- 1999-10-11 BG BG103794A patent/BG63205B1/bg unknown
- 1999-10-11 MA MA25812A patent/MA25007A1/fr unknown
- 1999-10-11 DK DK99307996T patent/DK0994115T3/da active
- 1999-10-11 ID IDP990941A patent/ID23351A/id unknown
- 1999-10-11 EG EG126999A patent/EG22630A/xx active
- 1999-10-11 EP EP99307996A patent/EP0994115B1/fr not_active Expired - Lifetime
- 1999-10-11 AT AT99307996T patent/ATE290003T1/de active
- 1999-10-12 EE EEP199900507A patent/EE04192B1/xx not_active IP Right Cessation
- 1999-10-12 UY UY25750A patent/UY25750A1/es not_active Application Discontinuation
- 1999-10-12 PL PL335959A patent/PL198150B1/pl not_active IP Right Cessation
- 1999-10-12 GE GEAP19995027A patent/GEP20022700B/en unknown
- 1999-10-12 CO CO99064776A patent/CO5150214A1/es unknown
- 1999-10-12 JP JP29009999A patent/JP3721021B2/ja not_active Expired - Fee Related
- 1999-10-12 HR HR990318A patent/HRP990318B1/xx not_active IP Right Cessation
- 1999-10-12 TR TR1999/02541A patent/TR199902541A2/xx unknown
- 1999-10-12 SG SG1999005097A patent/SG118060A1/en unknown
2001
- 2001-01-16 US US09/761,376 patent/US20010009962A1/en not_active Abandoned
2002
- 2002-09-23 US US10/253,029 patent/US20030069422A1/en not_active Abandoned
- 2002-11-18 IL IL15292402A patent/IL152924A0/xx unknown
- 2002-11-18 IL IL15292802A patent/IL152928A0/xx active IP Right Grant
- 2002-11-18 IL IL15292302A patent/IL152923A0/xx unknown
- 2002-11-18 IL IL15292602A patent/IL152926A0/xx unknown
- 2002-11-18 IL IL15292702A patent/IL152927A0/xx unknown

Also Published As

Publication number	Publication date
CZ353299A3 (cs)	2000-05-17
TR199902541A2 (xx)	2000-07-21
DZ2912A1 (fr)	2004-03-01
IL152924A (en)	2004-02-19
DK0994115T3 (da)	2005-06-20
IL152928A (en)	2007-07-04
KR100380954B1 (ko)	2003-04-21
HRP990318B1 (en)	2004-06-30
IL152926A0 (en)	2003-06-24
EP0994115A3 (fr)	2000-05-24
NO994943D0 (no)	1999-10-11
BG103794A (en)	2000-09-29
MA25007A1 (fr)	2000-07-01
AP9901672A0 (en)	1999-12-31
CO5150214A1 (es)	2002-04-29
US20030069422A1 (en)	2003-04-10
AR019244A1 (es)	2001-12-26
NO994943L (no)	2000-04-13
CU22928A3 (es)	2004-02-20
US20010009962A1 (en)	2001-07-26
IL152927A (en)	2004-06-01
ES2237049T3 (es)	2005-07-16
BG63205B1 (bg)	2001-06-29
AU5358199A (en)	2000-04-13
MY124620A (en)	2006-06-30
AP1233A (en)	2003-12-18
CZ296816B6 (cs)	2006-06-14
CA2285733A1 (fr)	2000-04-12
PE20001086A1 (es)	2000-10-18
TW589314B (en)	2004-06-01
CA2285733C (fr)	2004-08-24
TNSN99189A1 (fr)	2005-11-10
US6207829B1 (en)	2001-03-27
EA003774B1 (ru)	2003-08-28
IL152928A0 (en)	2003-06-24
JP2000119273A (ja)	2000-04-25
GT199900172A (es)	2001-03-28
IL152924A0 (en)	2003-06-24
PL198150B1 (pl)	2008-05-30
EP0994115B1 (fr)	2005-03-02
UA66787C2 (en)	2004-06-15
IL152927A0 (en)	2003-06-24
HK1027559A1 (en)	2001-01-19
KR20000028987A (ko)	2000-05-25
CR6118A (es)	2005-09-16
HUP9903469A3 (en)	2000-10-30
DE69923906D1 (de)	2005-04-07
BR9905092A (pt)	2000-08-08
ID23351A (id)	2000-04-13
EA199900822A3 (ru)	2000-08-28
EP0994115A2 (fr)	2000-04-19
IS1951B (is)	2004-10-13
IL132273A (en)	2004-06-20
IL152926A (en)	2004-02-19
CN1473831A (zh)	2004-02-11
AU756463B2 (en)	2003-01-16
HUP9903469A2 (hu)	2000-08-28
DE69923906T2 (de)	2006-04-06
HU9903469D0 (en)	1999-12-28
HU226162B1 (en)	2008-05-28
CN1255497A (zh)	2000-06-07
EE04192B1 (et)	2003-12-15
ZA996412B (en)	2001-04-11
GB9822238D0 (en)	1998-12-09
IL152923A0 (en)	2003-06-24
ATE290003T1 (de)	2005-03-15
IS5209A (is)	2000-04-13
HRP990318A2 (en)	2000-06-30
IL152923A (en)	2004-02-08
SI0994115T1 (fr)	2005-08-31
PL335959A1 (en)	2000-04-25
JP3721021B2 (ja)	2005-11-30
GEP20022700B (en)	2002-05-27
UY25750A1 (es)	2001-08-27
PT994115E (pt)	2005-06-30
OA11165A (en)	2003-04-22
EE9900507A (et)	2000-06-15
IL132273A0 (en)	2001-03-19
EA199900822A2 (ru)	2000-04-24
SG118060A1 (en)	2006-01-27
SK138599A3 (en)	2000-05-16
CN1207295C (zh)	2005-06-22
SK285215B6 (sk)	2006-09-07
NO313700B1 (no)	2002-11-18
RS49762B (sr)	2008-04-04
YU48999A (sh)	2002-06-19

Publication	Publication Date	Title
AP9901672A0 (en)	1999-12-31	Process for preparation of pyrazolo (4,3-d)pyrimidin-7- ones and intermediates thereof
AU8758298A (en)	1999-02-16	Process for the preparation of 2'-fluoro-5-methyl-beta -l-arabinofuranosyluridine
HUP9901176A3 (en)	2001-02-28	Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives and their intermediates
HUP0100640A3 (en)	2001-11-28	Process for the preparation of 1,4-dihydropyridines
IL133140A0 (en)	2001-03-19	Novel process for the preparation of 4-aryl-piperidines
EP0692476A3 (fr)	1997-09-03	Procédé amélioré pour la préparation de N,N'-carbonyldiazoles, spécialement de N,N'-carbonyldiimidazole
ZA963019B (en)	1996-10-22	Process for the preparation of 1,1-difluoroethane
HUP0003452A3 (en)	2002-12-28	Process for the preparation of 1-aryl-3-cyclopropyl-1,3-propanediones
ZA987741B (en)	1998-10-08	Process for the preparation of oxazaphosphorine-2-amines
HUP0001757A3 (en)	2002-12-28	Improved process for the preparation of halo-4-phenoxyquinolines
ZA988397B (en)	1999-03-24	Process for the preparation of substituted 5,6-dihydro-2H-pyran-2-ones
IL118731A (en)	2000-07-16	Process for the preparation of 2,2-dialkyl-arylidenecycloalkanones
IL135553A0 (en)	2001-05-20	Process for the preparation of azacycloalkyalkanoyl pseudotetrapeptides
HUP0102297A3 (en)	2003-07-28	Process for preparation of 4,5-epoxymorphinan-6-oxi-glucuronides
HUP9902745A3 (en)	2000-08-28	Process for the preparation of benzylcarbazate
ZA965515B (en)	1996-12-30	Process for the preparation of 3-hydroxyoxetanes
GB9807032D0 (en)	1998-06-03	Process for the preparation of (S)-3-carbethoxy-3-benzylpiperidine
IL120556A (en)	2000-11-21	Process for the preparation of 3,3,5-trichloroglutarimide
IL132237A (en)	2003-02-12	Process for the preparation of 3-isochromanone
ZA981924B (en)	1998-09-07	Process for the preparation of n-carboxylalkyl-3-fluoro-4- dialkylaminoanilines
MD956F1 (en)	1998-04-30	N-carboxyaryl-N',N'-dimethylthiouûreas preparation process
IL139521A0 (en)	2001-11-25	Process for preparation of 4,5-epoxymorphinan-6-oxyglucuronides
SG63715A1 (en)	1999-03-30	Process for the preparation of 2, 3-pyridinedicarboximides
IL119112A0 (en)	1996-11-14	Process for the preparation of 4,6-dichloropyrimidines
AU5222298A (en)	1998-06-03	Process for the preparation of 1,8-naphthosultam