EG25683A - Benzoxazine derivatives and uses thereof - Google Patents

Benzoxazine derivatives and uses thereof

Info

Publication number: EG25683A
Authority: EG; Egypt
Prior art keywords: benzoxazine derivatives; benzoxazine; derivatives
Prior art date: 2002-05-13

Application number

EG2003050432A

Other languages

English (en)

Inventor

Jacob Berger

Robin D Clark

Shu-Hai Zhao

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-13

Filing date

2003-05-10

Publication date

2012-05-16

2003-05-10 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2012-05-16 Application granted granted Critical

2012-05-16 Publication of EG25683A publication Critical patent/EG25683A/xx

Links

150000005130 benzoxazines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

EG2003050432A 2002-05-13 2003-05-10 Benzoxazine derivatives and uses thereof EG25683A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37800302P	2002-05-13	2002-05-13

Publications (1)

Publication Number	Publication Date
EG25683A true EG25683A (en)	2012-05-16

Family

ID=29420358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG2003050432A EG25683A (en)	2002-05-13	2003-05-10	Benzoxazine derivatives and uses thereof

Country Status (36)

Country	Link
US (4)	US6867204B2 (es)
EP (1)	EP1506179B1 (es)
JP (1)	JP4307377B2 (es)
KR (1)	KR100636475B1 (es)
CN (1)	CN100429206C (es)
AR (1)	AR039988A1 (es)
AT (1)	ATE316523T1 (es)
AU (1)	AU2003233231B2 (es)
BR (1)	BRPI0310032B8 (es)
CA (1)	CA2485136C (es)
DE (1)	DE60303376T2 (es)
DK (1)	DK1506179T3 (es)
EA (1)	EA009982B1 (es)
EC (1)	ECSP045420A (es)
EG (1)	EG25683A (es)
ES (1)	ES2256744T3 (es)
GT (1)	GT200300108A (es)
HR (1)	HRP20041030B1 (es)
IL (1)	IL164928A0 (es)
JO (1)	JO2413B1 (es)
MA (1)	MA27118A1 (es)
MX (1)	MXPA04011254A (es)
MY (1)	MY139612A (es)
NO (1)	NO329380B1 (es)
NZ (1)	NZ536230A (es)
PA (1)	PA8573501A1 (es)
PE (1)	PE20040757A1 (es)
PL (1)	PL211057B1 (es)
PT (1)	PT1506179E (es)
RS (1)	RS51042B (es)
TN (1)	TNSN04225A1 (es)
TW (1)	TWI258479B (es)
UA (1)	UA76877C2 (es)
UY (1)	UY27803A1 (es)
WO (1)	WO2003095434A1 (es)
ZA (1)	ZA200408783B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE424825T1 (de)	2001-07-20	2009-03-15	Psychogenics Inc	Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
BRPI0308696B8 (pt)	2002-03-27	2021-05-25	Axovant Sciences Gmbh	composto derivado de quinolina, seu processo de preparação, sua composição farmacêutica e seus usos
HRP20041030B1 (hr) *	2002-05-13	2013-03-31	F. Hoffmann - La Roche Ag	Derivati benzoksazina kao regulatori 5-ht6 i njihova upotreba
MXPA05004758A (es) *	2002-11-08	2005-08-02	Hoffmann La Roche	Benzoxazinonas sustituidas y uso de las mismas.
PT1558582E (pt)	2003-07-22	2006-05-31	Arena Pharm Inc	Derivados de diaril- e aril-heteroaril-ureia como moduladores do receptor de serotonina 5-ht2a uteis para a profilaxia e tratamento de desordens relacionadas com o mesmo
ES2291984T3 (es) *	2003-12-09	2008-03-01	F. Hoffmann-La Roche Ag	Derivados de benzoxazina y su empleo.
BRPI0506909A (pt) *	2004-01-16	2007-05-29	Hoffmann La Roche	derivados de 1-benzil-5piperazin-1-il-3,4 diidro-1h-quinazolin-2-ona e os respectivos derivados de 1h-benzo (1,2,6) tiadiazina-2,2-dióxido e 1,4-diidro-benzo (d) (1,3)oxazin-2-ona como moduladores do receptor de 5-hidroxitriptamina (5-ht) para o tratamento de doenças do sistema nervoso central
KR100823805B1 (ko) *	2004-05-05	2008-04-21	에프. 호프만-라 로슈 아게	5-ｈｔ6 수용체, 5-ｈｔ2ａ 수용체 또는 둘다를 조절하기에유용한 아릴설포닐 벤조다이옥산
US7713954B2 (en) *	2004-09-30	2010-05-11	Roche Palo Alto Llc	Compositions and methods for treating cognitive disorders
US7378415B2 (en) *	2004-09-30	2008-05-27	Roche Palo Alto Llc	Benzoxazine and quinoxaline derivatives and uses thereof
CN102114244A (zh) *	2004-09-30	2011-07-06	弗·哈夫曼-拉罗切有限公司	治疗认知障碍的组合物和方法
AU2005291541B2 (en) *	2004-09-30	2011-03-10	F. Hoffmann-La Roche Ag	Benzoxazine and quinoxaline derivatives and uses
EP2508177A1 (en)	2007-12-12	2012-10-10	Glaxo Group Limited	Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline
WO2009123714A2 (en)	2008-04-02	2009-10-08	Arena Pharmaceuticals, Inc.	Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en)	2008-10-28	2010-06-03	Arena Pharmaceuticals, Inc.	Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
AR078770A1 (es) *	2009-10-27	2011-11-30	Elara Pharmaceuticals Gmbh	Derivados de dihidrobenzo oxacinas y tiazinas, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades inflamatorias e hiperproliferativas.
KR101293384B1 (ko) *	2010-10-13	2013-08-05	주식회사 대웅제약	신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
US9403800B2 (en) *	2012-01-24	2016-08-02	Chemregen, Inc.	Compounds for inhibition of cancer cell proliferation
US10087151B2 (en)	2014-01-09	2018-10-02	The J. David Gladstone Institutes, A Testimentary Trust Established Under The Will Of J. David Gladstone	Substituted benzoxazine and related compounds
WO2016201373A1 (en)	2015-06-12	2016-12-15	Axovant Sciences Ltd.	Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
WO2017011767A2 (en)	2015-07-15	2017-01-19	Axovant Sciences Ltd.	Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1029479C (zh) *	1989-11-08	1995-08-09	山之内制药株式会社	新型苯并噁嗪衍生物的制备方法
US5492914A (en) *	1994-07-28	1996-02-20	Syntex (U.S.A.) Inc.	2-(1-azabicyclo[2.2.2]oct-3 s-yl)-6-hydroxy-2,4,5,6-tetrahydro-1H-benz[DE]is[2.2.2]oct-3's-yl)-6-hydroxy-2,3,3a,4,5,6-hexahydro-1h-benz [DE]isoquinolin-1-one and individual stereoisomers thereof
GB9507203D0 (en)	1995-04-07	1995-05-31	Smithkline Beecham Plc	Novel compounds
DZ2376A1 (fr) *	1996-12-19	2002-12-28	Smithkline Beecham Plc	Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
KR20010006487A (ko)	1997-04-18	2001-01-26	피터 기딩스	조합된 5ｈｔ1ａ, 5ｈｔ1ｂ 및 5ｈｔ1ｄ 수용체 길항 활성을 갖는 인돌 유도체
AU736256B2 (en)	1997-07-11	2001-07-26	Smithkline Beecham Plc	Novel compounds
CZ295937B6 (cs) *	1997-07-25	2005-12-14	H. Lundbeck A/S	Indolové nebo 2,3-dihydroindolové deriváty
GB9801392D0 (en)	1998-01-22	1998-03-18	Smithkline Beecham Plc	Novel compounds
HRP20000847A2 (en) *	1998-06-19	2001-12-31	Lundbeck & Co As H	4,5,6 i 7 - INDOLE AND INDOLINE DERIVATIVES, THEIR PREPARATION AND USE
GB9818916D0 (en)	1998-08-28	1998-10-21	Smithkline Beecham Plc	Use
US6380235B1 (en)	1999-05-04	2002-04-30	American Home Products Corporation	Benzimidazolones and analogues
AU772189B2 (en) *	1999-08-23	2004-04-08	Solvay Pharmaceuticals B.V.	New phenylpiperazines
US6566372B1 (en)	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
WO2001057003A1 (en)	2000-02-01	2001-08-09	Cor Therapeutics, Inc.	3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE INHIBITORS OF FACTOR Xa
HRP20041030B1 (hr) *	2002-05-13	2013-03-31	F. Hoffmann - La Roche Ag	Derivati benzoksazina kao regulatori 5-ht6 i njihova upotreba

2003
- 2003-05-05 HR HRP20041030AA patent/HRP20041030B1/hr not_active IP Right Cessation
- 2003-05-05 UA UA20041210144A patent/UA76877C2/uk unknown
- 2003-05-05 KR KR1020047018299A patent/KR100636475B1/ko not_active Expired - Fee Related
- 2003-05-05 AU AU2003233231A patent/AU2003233231B2/en not_active Expired
- 2003-05-05 DE DE60303376T patent/DE60303376T2/de not_active Expired - Lifetime
- 2003-05-05 WO PCT/EP2003/004671 patent/WO2003095434A1/en not_active Ceased
- 2003-05-05 CA CA2485136A patent/CA2485136C/en not_active Expired - Lifetime
- 2003-05-05 EA EA200401455A patent/EA009982B1/ru not_active IP Right Cessation
- 2003-05-05 AT AT03727430T patent/ATE316523T1/de active
- 2003-05-05 DK DK03727430T patent/DK1506179T3/da active
- 2003-05-05 EP EP03727430A patent/EP1506179B1/en not_active Expired - Lifetime
- 2003-05-05 PT PT03727430T patent/PT1506179E/pt unknown
- 2003-05-05 NZ NZ536230A patent/NZ536230A/en not_active IP Right Cessation
- 2003-05-05 PL PL374019A patent/PL211057B1/pl unknown
- 2003-05-05 CN CNB038109972A patent/CN100429206C/zh not_active Expired - Lifetime
- 2003-05-05 MX MXPA04011254A patent/MXPA04011254A/es active IP Right Grant
- 2003-05-05 ES ES03727430T patent/ES2256744T3/es not_active Expired - Lifetime
- 2003-05-05 BR BRPI0310032A patent/BRPI0310032B8/pt not_active IP Right Cessation
- 2003-05-05 RS YUP-970/04A patent/RS51042B/sr unknown
- 2003-05-05 JP JP2004503451A patent/JP4307377B2/ja not_active Expired - Lifetime
- 2003-05-08 JO JO200352A patent/JO2413B1/en active
- 2003-05-08 TW TW092112575A patent/TWI258479B/zh not_active IP Right Cessation
- 2003-05-09 US US10/435,732 patent/US6867204B2/en not_active Expired - Lifetime
- 2003-05-09 GT GT200300108A patent/GT200300108A/es unknown
- 2003-05-09 PA PA20038573501A patent/PA8573501A1/es unknown
- 2003-05-09 PE PE2003000452A patent/PE20040757A1/es active IP Right Grant
- 2003-05-09 AR ARP030101624A patent/AR039988A1/es active IP Right Grant
- 2003-05-10 EG EG2003050432A patent/EG25683A/xx active
- 2003-05-12 MY MYPI20031765A patent/MY139612A/en unknown
- 2003-05-12 UY UY27803A patent/UY27803A1/es not_active IP Right Cessation
2004
- 2004-10-28 IL IL16492804A patent/IL164928A0/xx unknown
- 2004-10-28 NO NO20044665A patent/NO329380B1/no not_active IP Right Cessation
- 2004-10-29 ZA ZA2004/08783A patent/ZA200408783B/en unknown
- 2004-11-10 EC EC2004005420A patent/ECSP045420A/es unknown
- 2004-11-11 TN TNP2004000225A patent/TNSN04225A1/fr unknown
- 2004-11-12 MA MA27944A patent/MA27118A1/fr unknown
2005
- 2005-01-31 US US11/047,284 patent/US20050130962A1/en not_active Abandoned
2009
- 2009-09-04 US US12/584,373 patent/US8377931B2/en not_active Expired - Fee Related
2012
- 2012-12-13 US US13/713,484 patent/US20130123251A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2256744T3 (es)	2006-07-16
US6867204B2 (en)	2005-03-15
JP4307377B2 (ja)	2009-08-05
BRPI0310032B8 (pt)	2021-05-25
AR039988A1 (es)	2005-03-09
JP2005530774A (ja)	2005-10-13
GT200300108A (es)	2004-03-15
AU2003233231B2 (en)	2009-02-26
PL374019A1 (en)	2005-09-19
NZ536230A (en)	2007-05-31
EP1506179B1 (en)	2006-01-25
TW200400188A (en)	2004-01-01
HK1080846A1 (zh)	2006-05-04
PA8573501A1 (es)	2003-12-10
CN100429206C (zh)	2008-10-29
PT1506179E (pt)	2006-06-30
EA009982B1 (ru)	2008-04-28
EP1506179A1 (en)	2005-02-16
US20130123251A1 (en)	2013-05-16
MA27118A1 (fr)	2004-12-20
DK1506179T3 (da)	2006-06-06
KR100636475B1 (ko)	2006-10-18
US8377931B2 (en)	2013-02-19
JO2413B1 (en)	2007-11-11
PE20040757A1 (es)	2004-11-06
AU2003233231A1 (en)	2003-11-11
DE60303376T2 (de)	2006-11-16
MY139612A (en)	2009-10-30
NO20044665L (no)	2004-12-03
MXPA04011254A (es)	2005-01-25
US20030232825A1 (en)	2003-12-18
UY27803A1 (es)	2003-11-28
TWI258479B (en)	2006-07-21
HRP20041030A2 (en)	2005-06-30
IL164928A0 (en)	2005-12-18
WO2003095434A1 (en)	2003-11-20
CA2485136C (en)	2011-12-20
NO329380B1 (no)	2010-10-04
BR0310032A (pt)	2005-02-15
UA76877C2 (uk)	2006-09-15
TNSN04225A1 (fr)	2007-03-12
ECSP045420A (es)	2005-01-03
DE60303376D1 (de)	2006-04-13
RS51042B (sr)	2010-10-31
ATE316523T1 (de)	2006-02-15
EA200401455A1 (ru)	2005-06-30
KR20040106538A (ko)	2004-12-17
ZA200408783B (en)	2005-12-28
US20050130962A1 (en)	2005-06-16
RS97004A (sr)	2006-10-27
US20090325950A1 (en)	2009-12-31
BRPI0310032B1 (pt)	2019-01-08
CA2485136A1 (en)	2003-11-20
CN1653054A (zh)	2005-08-10
PL211057B1 (pl)	2012-04-30
HRP20041030B1 (hr)	2013-03-31

Publication	Publication Date	Title
AU2003266321A1 (en)	2004-04-08	Tetrahydropyrimidine-2-one derivatives and their uses
EP1539941A4 (en)	2006-11-29	ADZYMES AND THEIR USES
EG25683A (en)	2012-05-16	Benzoxazine derivatives and uses thereof
AP1850A (en)	2008-05-26	Spiroindolineplperidine derivatives
GB0215823D0 (en)	2002-08-14	Quinazoline derivatives
IL166121A0 (en)	2006-01-15	Indole-3-sulphur derivatives
SI1847539T1 (sl)	2010-01-29	Kinazolinski derivati
IL166100A0 (en)	2006-01-15	7,8,9-10-tetrahydro-6h-azepino,6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2h-pyrroloÄ2,1-bÜ quinazolinone derivatives
IL163868A0 (en)	2005-12-18	Hermiasterlin derivatives and uses thereof
PL377770A1 (pl)	2006-02-20	Podstawione benzoksazynony i ich zastosowanie
IL175817A0 (en)	2006-10-05	Benzoxazine derivatives and uses thereof
IL174479A0 (en)	2006-08-01	Hemiasterlin derivatives and uses thereof
SI1551805T1 (sl)	2013-07-31	Substituirani gama-fenil-delta-laktami in njihova uporaba
AU2003299943A1 (en)	2004-07-22	Heterocycles and uses thereof
AU2003222659A8 (en)	2003-11-03	23-o-substituted 5-o-mycaminosyltylonide derivatives
IL165112A0 (en)	2005-12-18	Variant integrinpolypeptides and thereof
AU2003281691A1 (en)	2004-02-16	Furoisoquinoline derivative and use thereof
AU2003231827A8 (en)	2003-12-12	Pseudo-tissues and uses thereof
AU2003298739A8 (en)	2004-06-18	Intermedin and its uses
GB0316910D0 (en)	2003-08-20	Fluorocombretastatin and derivatives thereof
AU2003281698A8 (en)	2004-02-16	1-phenylpiperidin-3-one derivatives and processes for the preparation thereof
AU2003302173A8 (en)	2004-07-14	Spirotetrathiocarbamates and spirooxothiocarbamates
PL374817A1 (en)	2005-10-31	Quinazoline derivatives
EP1531854A4 (en)	2006-06-28	O-DERIVATED NOCATHIACIN DERIVATIVES
HUP0600155A2 (en)	2006-05-29	Early inflorescence-preferred regulatory elements and uses thereof