EP0723858A1 - Procédé pour la génération d'un diagramme force-distance des pistons d'une presse rotative à comprimées - Google Patents

Procédé pour la génération d'un diagramme force-distance des pistons d'une presse rotative à comprimées Download PDF

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Publication number
EP0723858A1
EP0723858A1 EP96100687A EP96100687A EP0723858A1 EP 0723858 A1 EP0723858 A1 EP 0723858A1 EP 96100687 A EP96100687 A EP 96100687A EP 96100687 A EP96100687 A EP 96100687A EP 0723858 A1 EP0723858 A1 EP 0723858A1
Authority
EP
European Patent Office
Prior art keywords
press
force
computer
pair
ram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP96100687A
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German (de)
English (en)
Other versions
EP0723858B1 (fr
Inventor
Jürgen Hinzpeter
Ingo Schmidt
Hans-Joachim Pierags
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fette GmbH
Original Assignee
Wilhelm Fette GmbH
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Publication date
Application filed by Wilhelm Fette GmbH filed Critical Wilhelm Fette GmbH
Publication of EP0723858A1 publication Critical patent/EP0723858A1/fr
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Publication of EP0723858B1 publication Critical patent/EP0723858B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/005—Control arrangements

Definitions

  • the invention relates to a method for creating a force-displacement diagram of the press ram of a rotary tablet press according to the preamble of claim 1.
  • the rotor of a rotary tablet press is equipped with a number of upper and lower punches, with each punch at certain positions on the circumference (pressing stations) of a vertical movement and the associated force during a rotor revolution subject to.
  • an ejector station should also be considered.
  • EP 0 431 269 It has become known from EP 0 431 269 to monitor the maximum pressing forces on the pressing rams in such a tableting machine.
  • the press forces are monitored in order to determine defects and to be able to sort out bad tablets in good time. Monitoring is also carried out in order to be able to continuously provide evidence of the quality of the tablets produced.
  • the position of the die disc rotating with the press rams is constantly monitored via an angle pulse generator.
  • a computer coordinates the specified maximum impulses with the press force values. For example, a load cell is assigned to the pressure rollers in the press stations.
  • the centered position of a pair of press rams in the area of a pair of pressure rollers defines the zero point from which the impulses start of the angular pulse generator are counted, with a certain number of angular pulses specifying the position of the next pair of press rams centered on the pair of pressure rollers in accordance with the division of the die plate. In this way, the maximum pressing force can be determined for all pairs of pressing dies in a tableting press.
  • the force-displacement diagram is of paramount importance for this. From a physical point of view, the force-displacement diagram describes the quantitative energy curve during tableting. With the help of the compression characteristic, conclusions can be drawn about the compressibility of certain substances and the properties of the tablet.
  • the compressibility is essentially determined by the pressure holding time, granulate state (moisture, particle size distribution), bulk volume, lubricant etc.
  • the tablet properties include tablet mass, disintegration time, active ingredient release, abrasion etc.
  • the invention is therefore based on the object of specifying a method in which the compression characteristics of a rotary press can be determined with minimal measurement effort under production conditions.
  • the course of the pressing force of at least one ram is measured in angular steps and stored in the computer.
  • One revolution of the rotor corresponds to 3,600 angular pulses, for example.
  • the theoretical values for the path of the press ram are stored in the computer. They can be calculated using appropriate geometric relationships, which will be discussed in more detail below. Decisive for this theoretical value is the diameter of the pressure roller, the shape of the stamp head and the relative position of these parts to each other.
  • a correction table is stored in the computer, which takes into account significant influencing variables on the actual stamp path, such as the spring deflection of the tablet press and the Hertzian pressure. Both the spring deflection and the Hertzian pressure are dependent on the pressing force exerted on the press ram by the pressure roller. Force-dependent correction factors are thus determined, which differ from the theoretical values for the stamp path must be deducted to determine the actual stamp path.
  • the size of the Hertzian pressure is also dependent on the relative position of the stamp head to the pressure roller.
  • the correction values therefore take into account the dependence of Hertzian pressure on the angular position of the ram.
  • the correction values for the Hertzian pressure and the spring deflection of the machine it is preferable to determine the correction values of the correction table in an empirical manner, in that a selected pair of press rams is moved on top of one another without intermediate molding compound for different infeed values.
  • the angular pulses can be used to scan and save the complete force curve of all stamps.
  • the paths of the punches can be determined and related to the force values in order to calculate the force / distance to be provided on a rotary tablet press.
  • the rotor 12 is indicated with a die plate 14 and from a number of press dies of the rotor 12 a pair of press dies with an upper press die 16 and a lower press die 18 in the region of an upper pressure roller 20 and a lower pressure roller 22
  • the rotor 12 is driven by a shaft 24 via an electric motor 26, a drive belt 28 and a transmission 30.
  • An angle pulse generator 32 is also seated on the shaft 24. with which the force that acts between the pressure roller and the stamp is measured when the stamps 16, 18 travel along between the pressure rollers 20, 22.
  • the pre-pressing or main pressing of a molding compound takes place in the die plate 14 to form a tablet or the like.
  • FIG. 2 shows the force-displacement diagram of a press die, for example the press die 16, during its movement under the pressure roller 20.
  • Arrow 38 indicates the rising branch of the diagram and arrow 40 the falling branch. Because of the compressibility of the press material and the springback behavior of the press material and the spring behavior of the press itself forms hysteresis, as indicated by the area of the diagram.
  • angular pulse generator 32 generates an angular pulse chain with the rotation of the rotor 12, for example one pulse per 0.1 ° rotation. It also generates an initial pulse defined by the central position of a pair of dies relative to a pair of pressure rollers.
  • FIG. 3 also shows how the force sensor 34 is also connected to the analog-digital converter 44 via a measuring amplifier 46. Its output goes to a machine computer 48.
  • An operating computer 50 is connected to the machine computer 48, with which the force-displacement diagram according to FIG. 2 is created in a manner to be described below.
  • Fig. 4 it can be seen that the stamp 16 covers a vertical path s during its horizontal movement relative to the stationary pressure roller 20.
  • the load cell 34 determines a force value per angular step, which is predetermined by the pulse series of the angular pulse generator 32.
  • the course of the force during the path s is indicated at 52 in FIG. 4.
  • angles of rotation are preferably selected in 0.1 ° steps according to the pulse interval of the angle pulse generator 32.
  • this theoretical total path must be corrected, namely by the total spring deflection of the tablet press and by the Hertzian surface pressure between the stamp head and the pressure roller.
  • the stamp head 54 touches the pressure roller 20 with a mirror surface, which means a line contact.
  • the actual stamp path for the first area is therefore the theoretical value given above minus the flattening in the first area minus the spring deflection. The same applies to the stamp path in the second area of the stamp head. The corresponding formulas for this are no longer listed.
  • correction values determined above are determined empirically. This is done in the following way.
  • a pair of measuring rams is installed in the tablet press and is moved directly onto one another without any molding compound.
  • various force-angle curves are generated by adjusting the web height (for example in 0.1 mm steps), as shown in FIG. 7.
  • s means the delivery of the pressure rollers.
  • the maxima are shown in a force correction path diagram 8 entered.
  • the theoretically calculated total value can be corrected. In the embodiment according to FIG. 3, this is done in the form of a table of values.
  • the theoretical die paths, which result from the calculation shown above, are stored in the operating computer.
  • the values for the correction table according to the diagram according to FIG. 8 are stored in the operating computer 50, so that a predetermined correction value is subtracted from the theoretical stamp value at a predetermined force.
  • the correction described so far is not sufficient because it is only correct for Hertzian pressure in the area of the maximum. Rather, the correction value described above must be subjected to further optimization.
  • the pressure roller 20 touches the stamp head 54 in a line which corresponds to the mirror diameter of the stamp head. Before and after this line gets shorter and shorter and then changes into a point contact.
  • the elastic penetration depth of the pressure roller into the stamp head also varies accordingly. Therefore with the help of the calculator not only the force maxima, but also the respective force values for the 0.1 ° steps for the different infeed values, as shown in FIG. 9. Knowing the geometric shape of the pressure roller and stamp head, the penetration depth for the individual angular steps is then determined for these forces using Hertzian pressure.
  • the original correction value is then corrected for the deviation of these values from the maximum values. These values are then entered in the force correction diagram.
  • This correction diagram can be seen in FIG. Depending on the angular step at which a correction has to be made, a different one of the curves shown in FIG. 10 is selected. It goes without saying that the correction diagram according to FIG. 10 is again stored in the operating computer 50 only in the form of a correction value table.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Control Of Presses (AREA)
  • Presses And Accessory Devices Thereof (AREA)
EP96100687A 1995-01-28 1996-01-18 Procédé pour la génération d'un diagramme force-distance des pistons d'une presse rotative à comprimées Expired - Lifetime EP0723858B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19502596A DE19502596C2 (de) 1995-01-28 1995-01-28 Meßgerät und Rechner zur Überprüfung der auf einer Rundläuferpresse hergestellten Tabletten der laufenden Produktion
DE19502596 1995-01-28

Publications (2)

Publication Number Publication Date
EP0723858A1 true EP0723858A1 (fr) 1996-07-31
EP0723858B1 EP0723858B1 (fr) 1999-04-07

Family

ID=7752484

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96100687A Expired - Lifetime EP0723858B1 (fr) 1995-01-28 1996-01-18 Procédé pour la génération d'un diagramme force-distance des pistons d'une presse rotative à comprimées

Country Status (4)

Country Link
US (1) US5699273A (fr)
EP (1) EP0723858B1 (fr)
JP (1) JP3713639B2 (fr)
DE (2) DE19502596C2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839638A3 (fr) * 1996-10-30 1998-12-30 KORSCH PRESSEN GmbH Procédé de fabrication de la surface de la tête du poinçon qui coopère avec un rouleau de pression cylindrique pour les presses à table rotative et poinçon ainsi fabriqué

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5996404A (en) * 1998-08-24 1999-12-07 Westvaco Corporation On-line dense paste rheological testing apparatus and method
DE19911294C1 (de) * 1999-03-13 2000-06-15 Fette Wilhelm Gmbh Einstellverfahren für eine Rundläufertablettenpresse mit einem Winkelimpulsgeber zur Ermittlung des Preßkraftverlaufs an den einzelnen Stempeln in mindestens einer Preßstation
DE19958999A1 (de) * 1999-12-08 2001-04-26 Henkel Kgaa Verfahren und Vorrichtung zur Regelung von Tablettenpressen
DE10142772C2 (de) * 2001-08-31 2003-09-25 Fette Wilhelm Gmbh Verfahren zur Herstellung von Pressteilen in einer Pulverpresse
US6865498B2 (en) * 2001-11-30 2005-03-08 Thermwood Corporation System for calibrating the axes on a computer numeric controlled machining system and method thereof
DE10212959A1 (de) * 2002-03-22 2003-10-16 Wolfram Minke Vorrichtung zur Herstellung von Preßlingen
WO2003095121A1 (fr) * 2002-05-14 2003-11-20 Fundacion Robotiker Procede de fabrication d'emporte-pieces
ES2310429B1 (es) * 2002-05-14 2009-11-11 Fundacion Robotiker Procedimiento de fabricacion de troqueles.
ES2242141T3 (es) * 2003-02-10 2005-11-01 Korsch Ag Metodo y dispositivo para el control de una maquina rotativa para la fabricacion de tabletas.
DE102005051567B4 (de) * 2005-10-20 2010-01-07 Korsch Ag Rundläufer-Tablettiermaschine sowie Verfahren und Vorrichtung zur Wegmessung eines Stempels einer Rundläufer-Tablettiermaschine
DE102008015820B4 (de) 2008-03-27 2013-02-28 Fette Compacting Gmbh Vorrichtung und Verfahren zur Messung der vertikalen Position von Ober- und Unterstempeln einer Rundläufer-Tablettenpresse
DE102008020748B4 (de) * 2008-04-23 2010-12-30 Fette Gmbh Stempel für eine Rundläuferpresse
DE102009031367B3 (de) * 2009-07-02 2010-09-02 Fette Gmbh Pressstempel für eine Rundläuferpresse
DE102013202975B4 (de) * 2013-02-22 2015-02-05 Korsch Ag Einzelsortiervorrichtung zur sortierung von tabletten, system mit einer solchen einzelsortiervorrichtung und mit einer tablettiervorrichtung und verfahren zur überprüfung einer einzelsortiervorrichtung
JP7406627B2 (ja) 2019-09-27 2023-12-27 コルシュ アーゲー プレスパンチに取り付けられた測定装置によって錠剤プレス機を好ましくは継続的な動作中に監視する装置及び方法
DE102022131493A1 (de) * 2022-11-29 2024-05-29 Fette Compacting Gmbh Verfahren zum Bewerten des Zustands von Pressstempeln einer Rundläuferpresse sowie Rundläuferpresse

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3229988A1 (de) * 1981-08-12 1983-03-10 Amada Co. Ltd., Isehara, Kanagawa Verfahren und einrichtungen zur steuerung von pressen
DE3520203A1 (de) * 1985-06-05 1986-12-11 Wilhelm Fette Gmbh, 2053 Schwarzenbek Rundlaeufer-tablettiermaschine und verfahren zur steuerung ihrer druckrollen
EP0431269A1 (fr) * 1989-12-02 1991-06-12 Wilhelm Fette GmbH Procédé et dispositif de surveillance des forces de compression d'une machine de production des comprimés
US5229044A (en) * 1992-04-28 1993-07-20 Kikusui Seisakusho Ltd. Method of checking a pickup load cell in a rotary tableting machine
US5322655A (en) * 1993-02-19 1994-06-21 Thomas Engineering, Inc. Method for monitoring and controlling the weights of each layer of a multilayer tablet

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US504311A (en) * 1893-08-29 Pegging-machine
US4177517A (en) * 1976-07-07 1979-12-04 Mette Klaus H Monitoring device for power presses
DE3823417A1 (de) * 1988-07-11 1990-01-18 Fette Wilhelm Gmbh Verfahren und einrichtung zum ueberwachen der presskraefte der stempel einer tablettenpresse
FR2638118A1 (fr) * 1988-10-20 1990-04-27 Adl Automation Procede et appareil pour la compression et le controle de la compression de matieres pulverulentes et presse en faisant application
DE3919821C2 (de) * 1989-06-15 1994-04-07 Mannesmann Ag Verfahren und Vorrichtung zum Herstellen von maßhaltigen Preßlingen
DE3930475A1 (de) * 1989-09-12 1991-03-14 Dorst Masch & Anlagen Presse zur herstellung masshaltiger presslinge aus pulverfoermigem material
US5223192A (en) * 1989-12-02 1993-06-29 Firma Wilhelm Fette Gmbh Method of and arrangement for monitoring pressing forces in a pelletizing machine
US5211964A (en) * 1991-05-20 1993-05-18 Westinghouse Electric Corp. Press machine with means to adjust punching force
CH683243A5 (de) * 1991-11-15 1994-02-15 Laeis & Bucher Gmbh Verfahren zur Steuerung und/oder Regelung des Pressvorganges einer Steinpresse.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3229988A1 (de) * 1981-08-12 1983-03-10 Amada Co. Ltd., Isehara, Kanagawa Verfahren und einrichtungen zur steuerung von pressen
DE3520203A1 (de) * 1985-06-05 1986-12-11 Wilhelm Fette Gmbh, 2053 Schwarzenbek Rundlaeufer-tablettiermaschine und verfahren zur steuerung ihrer druckrollen
EP0431269A1 (fr) * 1989-12-02 1991-06-12 Wilhelm Fette GmbH Procédé et dispositif de surveillance des forces de compression d'une machine de production des comprimés
US5229044A (en) * 1992-04-28 1993-07-20 Kikusui Seisakusho Ltd. Method of checking a pickup load cell in a rotary tableting machine
US5322655A (en) * 1993-02-19 1994-06-21 Thomas Engineering, Inc. Method for monitoring and controlling the weights of each layer of a multilayer tablet

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839638A3 (fr) * 1996-10-30 1998-12-30 KORSCH PRESSEN GmbH Procédé de fabrication de la surface de la tête du poinçon qui coopère avec un rouleau de pression cylindrique pour les presses à table rotative et poinçon ainsi fabriqué
US6056532A (en) * 1996-10-30 2000-05-02 Korsch Pressen Gmbh Process for manufacturing the head surfaces of dies cooperating with cylindrical pressure rollers for rotary presses and die manufactured according to this process

Also Published As

Publication number Publication date
JP3713639B2 (ja) 2005-11-09
DE19502596C2 (de) 1997-08-28
JPH08276127A (ja) 1996-10-22
DE19502596A1 (de) 1996-08-14
DE59601573D1 (de) 1999-05-12
EP0723858B1 (fr) 1999-04-07
US5699273A (en) 1997-12-16

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