EP2453236A3 - Indicateur de charge biologique et procédé de mesure de charge biologique - Google Patents
Indicateur de charge biologique et procédé de mesure de charge biologique Download PDFInfo
- Publication number
- EP2453236A3 EP2453236A3 EP12154982A EP12154982A EP2453236A3 EP 2453236 A3 EP2453236 A3 EP 2453236A3 EP 12154982 A EP12154982 A EP 12154982A EP 12154982 A EP12154982 A EP 12154982A EP 2453236 A3 EP2453236 A3 EP 2453236A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- csf
- fatigue
- stress
- factors
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 108050006947 CXC Chemokine Proteins 0.000 abstract 2
- 102000019388 CXC chemokine Human genes 0.000 abstract 2
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 230000003340 mental effect Effects 0.000 abstract 2
- 238000012360 testing method Methods 0.000 abstract 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 1
- 102000005862 Angiotensin II Human genes 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- 108010081589 Becaplermin Proteins 0.000 abstract 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 abstract 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 abstract 1
- 102100032367 C-C motif chemokine 5 Human genes 0.000 abstract 1
- 102100032366 C-C motif chemokine 7 Human genes 0.000 abstract 1
- 101710155834 C-C motif chemokine 7 Proteins 0.000 abstract 1
- 102100025248 C-X-C motif chemokine 10 Human genes 0.000 abstract 1
- 101710098275 C-X-C motif chemokine 10 Proteins 0.000 abstract 1
- 108700012434 CCL3 Proteins 0.000 abstract 1
- -1 CSF-3 Proteins 0.000 abstract 1
- 102000000013 Chemokine CCL3 Human genes 0.000 abstract 1
- 108010055165 Chemokine CCL4 Proteins 0.000 abstract 1
- 102000001326 Chemokine CCL4 Human genes 0.000 abstract 1
- 108010055166 Chemokine CCL5 Proteins 0.000 abstract 1
- 102100023688 Eotaxin Human genes 0.000 abstract 1
- 101710139422 Eotaxin Proteins 0.000 abstract 1
- 101150021185 FGF gene Proteins 0.000 abstract 1
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 abstract 1
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 abstract 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
- 102100037850 Interferon gamma Human genes 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 108090000174 Interleukin-10 Proteins 0.000 abstract 1
- 108090000177 Interleukin-11 Proteins 0.000 abstract 1
- 108010065805 Interleukin-12 Proteins 0.000 abstract 1
- 108090000176 Interleukin-13 Proteins 0.000 abstract 1
- 108090000172 Interleukin-15 Proteins 0.000 abstract 1
- 108050003558 Interleukin-17 Proteins 0.000 abstract 1
- 108090000171 Interleukin-18 Proteins 0.000 abstract 1
- 108010002350 Interleukin-2 Proteins 0.000 abstract 1
- 108010002386 Interleukin-3 Proteins 0.000 abstract 1
- 108090000978 Interleukin-4 Proteins 0.000 abstract 1
- 108010002616 Interleukin-5 Proteins 0.000 abstract 1
- 108090001005 Interleukin-6 Proteins 0.000 abstract 1
- 108010002586 Interleukin-7 Proteins 0.000 abstract 1
- 108090001007 Interleukin-8 Proteins 0.000 abstract 1
- 108010002335 Interleukin-9 Proteins 0.000 abstract 1
- 108090000099 Neurotrophin-4 Proteins 0.000 abstract 1
- 102100033857 Neurotrophin-4 Human genes 0.000 abstract 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 abstract 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 102000015736 beta 2-Microglobulin Human genes 0.000 abstract 1
- 108010081355 beta 2-Microglobulin Proteins 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 108040001669 interleukin-1 receptor antagonist activity proteins Proteins 0.000 abstract 1
- 102000009634 interleukin-1 receptor antagonist activity proteins Human genes 0.000 abstract 1
- OHDXDNUPVVYWOV-UHFFFAOYSA-N n-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine Chemical compound CNCC1=CC=CC=C1SC1=CC=CC2=CC=CC=C12 OHDXDNUPVVYWOV-UHFFFAOYSA-N 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/301—Anxiety or phobic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/302—Schizophrenia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/304—Mood disorders, e.g. bipolar, depression
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/30—Psychoses; Psychiatry
- G01N2800/306—Chronic fatigue syndrome
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006041633 | 2006-02-17 | ||
| EP07714417.8A EP2006680B1 (fr) | 2006-02-17 | 2007-02-16 | Indicateur d'une charge biologique et procede permettant de mesurer la charge biologique |
Related Parent Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP07714417.8A Division-Into EP2006680B1 (fr) | 2006-02-17 | 2007-02-16 | Indicateur d'une charge biologique et procede permettant de mesurer la charge biologique |
| EP07714417.8 Division | 2007-02-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2453236A2 EP2453236A2 (fr) | 2012-05-16 |
| EP2453236A3 true EP2453236A3 (fr) | 2012-08-22 |
Family
ID=38371648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP07714417.8A Active EP2006680B1 (fr) | 2006-02-17 | 2007-02-16 | Indicateur d'une charge biologique et procede permettant de mesurer la charge biologique |
| EP12154982A Withdrawn EP2453236A3 (fr) | 2006-02-17 | 2007-02-16 | Indicateur de charge biologique et procédé de mesure de charge biologique |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP07714417.8A Active EP2006680B1 (fr) | 2006-02-17 | 2007-02-16 | Indicateur d'une charge biologique et procede permettant de mesurer la charge biologique |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20100233818A1 (fr) |
| EP (2) | EP2006680B1 (fr) |
| JP (1) | JP5069213B2 (fr) |
| KR (1) | KR101473495B1 (fr) |
| CN (1) | CN101454669B (fr) |
| AU (1) | AU2007215739B2 (fr) |
| BR (1) | BRPI0707958B8 (fr) |
| CA (1) | CA2642706C (fr) |
| CY (1) | CY1115418T1 (fr) |
| DK (1) | DK2006680T3 (fr) |
| ES (1) | ES2474690T3 (fr) |
| HR (1) | HRP20140673T1 (fr) |
| IL (1) | IL193496A (fr) |
| MY (1) | MY151424A (fr) |
| NZ (1) | NZ571018A (fr) |
| PL (1) | PL2006680T3 (fr) |
| PT (1) | PT2006680E (fr) |
| RU (1) | RU2519324C2 (fr) |
| SI (1) | SI2006680T1 (fr) |
| WO (1) | WO2007094472A1 (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8158374B1 (en) | 2006-09-05 | 2012-04-17 | Ridge Diagnostics, Inc. | Quantitative diagnostic methods using multiple parameters |
| CN102037355A (zh) * | 2008-03-04 | 2011-04-27 | 里奇诊断学股份有限公司 | 基于多重生物标记物板块诊断和监测抑郁症 |
| EP2272044A4 (fr) * | 2008-03-12 | 2011-07-06 | Ridge Diagnostics Inc | Biomarqueurs d'inflammation pour la surveillance de troubles de dépression |
| JP5219048B2 (ja) * | 2008-09-17 | 2013-06-26 | 独立行政法人農業・食品産業技術総合研究機構 | 抗豚インターロイキン−18抗体を用いた動物のストレス評価方法 |
| EP2337866B1 (fr) * | 2008-10-15 | 2014-07-30 | Ridge Diagnostics, Inc. | Mappage sur hyperespace multidimensionnel de biomarqueur humain pour des troubles dépressifs |
| WO2010059709A2 (fr) * | 2008-11-18 | 2010-05-27 | Ridge Diagnostics, Inc. | Biomarqueurs de syndrome métabolique et d'axe hpa pour un trouble dépressif majeur |
| CA2757518A1 (fr) * | 2009-04-01 | 2010-10-07 | Ridge Diagnostics, Inc. | Biomarqueurs pour controler le traitement de maladies neuropsychiatriques |
| CN102460153A (zh) * | 2009-04-06 | 2012-05-16 | 里奇诊断学股份有限公司 | 监控神经精神疾病治疗的生物标记 |
| WO2010119769A1 (fr) * | 2009-04-14 | 2010-10-21 | 片倉工業株式会社 | Procédé d'évaluation du stress chronique |
| JP5553525B2 (ja) * | 2009-04-17 | 2014-07-16 | 敦生 関山 | 生体負荷の指標剤および生体負荷の測定方法 |
| WO2011094308A2 (fr) * | 2010-01-26 | 2011-08-04 | Ridge Diagnostics, Inc. | Panels de marqueurs biologiques multiples pour stratifier la sévérité d'une maladie et pour surveiller le traitement d'une dépression |
| JP5821447B2 (ja) * | 2011-09-13 | 2015-11-24 | 大正製薬株式会社 | カルジオリピンを用いた疲労の判定方法 |
| CN104937414A (zh) * | 2012-10-24 | 2015-09-23 | 夏洛特-梅克伦堡医院(商业用名:卡罗来纳保健系统) | 用于鉴定肝损伤的生物标记 |
| JP5710666B2 (ja) * | 2013-02-25 | 2015-04-30 | 敦生 関山 | 生体負荷の指標剤および生体負荷の測定方法 |
| JP6205175B2 (ja) | 2013-05-16 | 2017-10-04 | 株式会社Resvo | 精神・神経疾患バイオマーカー |
| CA3112130A1 (fr) * | 2013-07-11 | 2015-01-15 | University Of North Texas Health Science Center At Fort Worth | Depistage base sur le sang pour la detection d'une maladie neurologique dans des installations de soins primaires |
| AU2014354808A1 (en) | 2013-11-26 | 2016-06-02 | University Of North Texas Health Science Center At Fort Worth | Personalized medicine approach for treating cognitive loss |
| JPWO2015174544A1 (ja) * | 2014-05-16 | 2017-04-20 | 国立研究開発法人国立精神・神経医療研究センター | 精神疾患判定マーカー |
| CA2998533A1 (fr) * | 2015-10-08 | 2017-04-13 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Biomarqueurs pour le diagnostic du trouble de stress post-traumatique |
| CN106814145B (zh) * | 2016-12-20 | 2019-08-30 | 河北工程大学 | 一种人体疲劳测定方法 |
| RU2630605C1 (ru) * | 2017-01-09 | 2017-09-11 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью | Способ оценки риска нарушения здоровья работников титано-магниевого производства, режим труда которых включает ночные смены |
| CN106706929B (zh) * | 2017-01-22 | 2019-01-18 | 河北工程大学 | 一种利用唾液检测人体疲劳的方法 |
| CN108333362B (zh) * | 2017-12-21 | 2021-04-02 | 河北工程大学 | 一种人体疲劳测定方法 |
| WO2019143562A1 (fr) | 2018-01-18 | 2019-07-25 | University Of North Texas Health Science Center At Fort Worth | Diagnostic compagnon pour ains et donépézil pour le traitement de sous-populations spécifiques de patients souffrant de la maladie d'alzheimer |
| WO2020241809A1 (fr) * | 2019-05-31 | 2020-12-03 | 日本たばこ産業株式会社 | Procédé d'évaluation de sensation de bonheur et procédé d'acquisition de données pour évaluer la sensation de bonheur |
| CN112716505A (zh) * | 2020-12-08 | 2021-04-30 | 河北工程大学 | 一种快速的疲劳检测方法 |
| CN113180595A (zh) * | 2021-03-25 | 2021-07-30 | 河北工程大学 | 基于人体唾液蛋白测定重点行业职业疲劳程度的检测系统 |
| CN113151443B (zh) * | 2021-04-16 | 2022-07-01 | 中央民族大学 | 细胞因子联合分析作为精神分裂症标志物及其应用 |
| JP7767055B2 (ja) * | 2021-08-16 | 2025-11-11 | 株式会社Lsiメディエンス | 精神ストレスの定量法 |
| KR102530616B1 (ko) * | 2022-09-22 | 2023-05-10 | 주식회사 메디푸드플랫폼 | 의과학 및 성분학 기반의 정신 상태 분석 장치, 방법 및 프로그램 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030224345A1 (en) * | 2001-08-24 | 2003-12-04 | Advanced Cell Technology | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
| WO2004009618A2 (fr) * | 2002-07-18 | 2004-01-29 | Crucell Holland B.V. | Production par recombinaison de melanges d'anticorps |
| WO2005017203A2 (fr) * | 2003-07-11 | 2005-02-24 | Yale University | Systemes et methodes permettant de diagnostiquer et de traiter des troubles psychologiques et des troubles du comportement |
| US20050208519A1 (en) * | 2004-03-12 | 2005-09-22 | Genenews Inc. | Biomarkers for diagnosing schizophrenia and bipolar disorder |
| US20050245557A1 (en) * | 2003-10-15 | 2005-11-03 | Pain Therapeutics, Inc. | Methods and materials useful for the treatment of arthritic conditions, inflammation associated with a chronic condition or chronic pain |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| US7135458B1 (en) * | 1995-11-15 | 2006-11-14 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use |
| JP4004088B2 (ja) * | 1995-09-26 | 2007-11-07 | 株式会社林原生物化学研究所 | 免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質 |
| JP2724987B2 (ja) | 1994-11-15 | 1998-03-09 | 株式会社林原生物化学研究所 | インターフェロン−γの産生を誘導するポリペプチド |
| JP2952750B2 (ja) * | 1995-02-23 | 1999-09-27 | 株式会社林原生物化学研究所 | モノクローナル抗体 |
| US6207641B1 (en) * | 1995-03-10 | 2001-03-27 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pharmaceutical composition containing IFN-γ inducing polypeptide or factor for treating and/or preventing IFN-γ susceptive diseases |
| JP4490576B2 (ja) * | 1999-10-26 | 2010-06-30 | 富山化学工業株式会社 | 中枢神経系作用薬のスクリーニング方法及びストレス状態の評価方法 |
| JP2005124565A (ja) * | 2003-09-29 | 2005-05-19 | Sogo Ikagaku Kenkyusho:Kk | 新規神経ペプチド及びその利用 |
| EP2177907B1 (fr) | 2004-06-30 | 2014-01-01 | Atsuo Sekiyama | Agent indicateur d'une réponse au stress non inflammatoire et son utilisation |
| JP4645939B2 (ja) | 2004-07-22 | 2011-03-09 | 日本電気株式会社 | 移動基地局位置決定システム、端末位置決定システム、移動基地局、無線端末及び基地局位置決定プログラム |
-
2007
- 2007-02-16 WO PCT/JP2007/052887 patent/WO2007094472A1/fr not_active Ceased
- 2007-02-16 HR HRP20140673TT patent/HRP20140673T1/hr unknown
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030224345A1 (en) * | 2001-08-24 | 2003-12-04 | Advanced Cell Technology | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
| WO2004009618A2 (fr) * | 2002-07-18 | 2004-01-29 | Crucell Holland B.V. | Production par recombinaison de melanges d'anticorps |
| WO2005017203A2 (fr) * | 2003-07-11 | 2005-02-24 | Yale University | Systemes et methodes permettant de diagnostiquer et de traiter des troubles psychologiques et des troubles du comportement |
| US20050245557A1 (en) * | 2003-10-15 | 2005-11-03 | Pain Therapeutics, Inc. | Methods and materials useful for the treatment of arthritic conditions, inflammation associated with a chronic condition or chronic pain |
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| TSUANG M T ET AL: "Assessing the validity of blood-based gene expression profiles for the classification of schizophrenia and bipolar disorder: A preliminary report", AMERICAN JOURNAL OF MEDICAL GENETICS, WILEY, NEW YORK,NY, US, vol. 133B, no. 1, 5 February 2005 (2005-02-05), pages 1 - 5, XP002368087, ISSN: 0148-7299 * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2519324C2 (ru) | 2014-06-10 |
| CN101454669B (zh) | 2013-11-20 |
| CY1115418T1 (el) | 2017-01-04 |
| CN101454669A (zh) | 2009-06-10 |
| SI2006680T1 (sl) | 2014-08-29 |
| PT2006680E (pt) | 2014-07-14 |
| PL2006680T3 (pl) | 2014-09-30 |
| MY151424A (en) | 2014-05-30 |
| EP2006680A1 (fr) | 2008-12-24 |
| HRP20140673T1 (hr) | 2014-10-10 |
| BRPI0707958A2 (pt) | 2011-05-17 |
| RU2008137234A (ru) | 2010-03-27 |
| EP2453236A2 (fr) | 2012-05-16 |
| NZ571018A (en) | 2012-03-30 |
| BRPI0707958B1 (pt) | 2018-10-16 |
| DK2006680T3 (da) | 2014-06-23 |
| EP2006680A4 (fr) | 2009-09-09 |
| IL193496A0 (en) | 2009-05-04 |
| JPWO2007094472A1 (ja) | 2009-07-09 |
| AU2007215739B2 (en) | 2014-01-16 |
| US20100233818A1 (en) | 2010-09-16 |
| JP5069213B2 (ja) | 2012-11-07 |
| IL193496A (en) | 2015-07-30 |
| CA2642706A1 (fr) | 2007-08-23 |
| WO2007094472A1 (fr) | 2007-08-23 |
| EP2006680B1 (fr) | 2014-04-16 |
| CA2642706C (fr) | 2017-08-01 |
| HK1133461A1 (en) | 2010-03-26 |
| KR101473495B1 (ko) | 2014-12-17 |
| KR20090007289A (ko) | 2009-01-16 |
| AU2007215739A1 (en) | 2007-08-23 |
| BRPI0707958B8 (pt) | 2021-07-27 |
| ES2474690T3 (es) | 2014-07-09 |
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