ES2014546A6 - Procedimiento para la obtencion de fctor activador de neutrofilos. - Google Patents

Procedimiento para la obtencion de fctor activador de neutrofilos.

Info

Publication number
ES2014546A6
ES2014546A6 ES8803530A ES8803530A ES2014546A6 ES 2014546 A6 ES2014546 A6 ES 2014546A6 ES 8803530 A ES8803530 A ES 8803530A ES 8803530 A ES8803530 A ES 8803530A ES 2014546 A6 ES2014546 A6 ES 2014546A6
Authority
ES
Spain
Prior art keywords
activating factor
neutrophil
perform
naf
recovery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8803530A
Other languages
English (en)
Inventor
Heinrich Aschauer
Ivan J D Lindley
Paola Peveri
Alfred Walz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kocher Theodor Institut
Sandoz AG
Original Assignee
Kocher Theodor Institut
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27263673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2014546(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878727053A external-priority patent/GB8727053D0/en
Priority claimed from GB888805070A external-priority patent/GB8805070D0/en
Priority claimed from GB888825258A external-priority patent/GB8825258D0/en
Application filed by Kocher Theodor Institut, Sandoz AG filed Critical Kocher Theodor Institut
Publication of ES2014546A6 publication Critical patent/ES2014546A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5421—IL-8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE FACTOR ACTIVADOR DE NEUTROFILOS (NAF), CARACTERIZADO PORQUE COMPRENDE PURIFICAR, MEDIANTE CROMATOGRAFIA, LA INFRACCION SOBRENADANTE DE CULTIVOS DE MONOCITOS HUMANOS Y EFECTUAR A CONTINUACION UNA ETAPA DE RECUPERACION; O BIEN SINTETIZAR, PURIFICAR Y LIGAR LOS CORRESPONDIENTES OLIGONUCLEOTIDOS, CLONAR EL GEN DE NAF SINTETICO RESULTANTE, EXPRESAR Y EFECTUAR ENTONCES LAS ETAPAS DE RECUPERACION Y PURIFICACION.
ES8803530A 1987-11-19 1988-11-18 Procedimiento para la obtencion de fctor activador de neutrofilos. Expired - Lifetime ES2014546A6 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878727053A GB8727053D0 (en) 1987-11-19 1987-11-19 Neutrophil-activating factor(naf)
GB888805070A GB8805070D0 (en) 1988-03-03 1988-03-03 Neutrophil-activating factor(naf)
GB888825258A GB8825258D0 (en) 1988-10-28 1988-10-28 Neutrophil-activating factor

Publications (1)

Publication Number Publication Date
ES2014546A6 true ES2014546A6 (es) 1990-07-16

Family

ID=27263673

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803530A Expired - Lifetime ES2014546A6 (es) 1987-11-19 1988-11-18 Procedimiento para la obtencion de fctor activador de neutrofilos.

Country Status (23)

Country Link
US (1) US6383479B1 (es)
JP (1) JP3133305B2 (es)
KR (1) KR890701625A (es)
AT (1) ATA901588A (es)
AU (1) AU622125B2 (es)
BE (1) BE1001817A5 (es)
CH (1) CH680001A5 (es)
DE (2) DE3890998B4 (es)
DK (1) DK354389A (es)
ES (1) ES2014546A6 (es)
FI (1) FI893474A7 (es)
FR (1) FR2623400B1 (es)
GB (1) GB2223225B (es)
GR (1) GR880100775A (es)
HU (1) HU205617B (es)
IL (1) IL88404A0 (es)
IT (1) IT1224574B (es)
NL (1) NL194982C (es)
NZ (1) NZ226990A (es)
PL (1) PL275881A1 (es)
PT (1) PT89026B (es)
SE (1) SE8902507D0 (es)
WO (1) WO1989004836A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652338A (en) 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
JPH03505730A (ja) * 1988-07-07 1991-12-12 アメリカ合衆国 ヒトにヒト好中球走化因子を投与することによる免疫不全状態に起因する疾患の治療法
EP0429542B1 (en) * 1988-08-15 1995-12-06 Brigham And Women's Hospital Leukocyte adhesion inhibitor
ATE113312T1 (de) * 1988-08-29 1994-11-15 Us Gov Health & Human Serv Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist.
JP2844260B2 (ja) * 1988-11-10 1999-01-06 ステファン チャールズ マックケイブ シャワーヘッド組立体
US5241049A (en) * 1989-12-22 1993-08-31 Zymogenetics, Inc. Neutrophil chemoattractants
US5079228A (en) * 1990-02-05 1992-01-07 Board Of Regents, The University Of Texas System Peptide inhibitors of neutrophil activating factor induced chemotaxis
IE913192A1 (en) * 1990-09-12 1992-02-25 Scripps Research Inst Active site of interleukin-8: polypeptide analogs and¹antibodies
WO1993001826A1 (en) * 1991-07-19 1993-02-04 East Carolina University Method of treating asthma
US5401651A (en) * 1991-10-16 1995-03-28 Walz; Alfred DNA encoding ENA-78, a neutrophil activating factor
GB9124775D0 (en) * 1991-11-21 1992-01-15 Medical Res Council Cervical ripening
US5665346A (en) * 1991-12-04 1997-09-09 Research Corporation Technologies, Inc. Human interleukin-8 analogs
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
JP7727557B2 (ja) * 2019-06-27 2025-08-21 バイナリ， エルエルシー 絶対好中球機能（ａｎｆ）の臨床現場（ｐｏｃ）診断検査臨床現場（ｐｏｃ）測定に適用可能な全血および体液中の食作用性白血球のオキシダーゼベースの化学発光アッセイ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737703A1 (de) * 1987-11-06 1989-05-18 Ferring Arzneimittel Gmbh Neutrophilen aktivierendes polypeptid, verfahren zu dessen herstellung sowie dessen verwendung als arzneimittel und diagnostikum
US5652338A (en) * 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
ATE116366T1 (de) 1988-05-02 1995-01-15 Us Health Verfahren zur herstellung eines menschlichen ''neutrophil chemotactic factor''-polypeptids.
EP0429542B1 (en) 1988-08-15 1995-12-06 Brigham And Women's Hospital Leukocyte adhesion inhibitor
AU4665689A (en) * 1989-12-11 1991-07-18 Wallac Oy Elastic scintillator material

Also Published As

Publication number Publication date
HU205617B (en) 1992-05-28
GB2223225B (en) 1992-07-08
WO1989004836A1 (en) 1989-06-01
BE1001817A5 (fr) 1990-03-13
FI893474A0 (fi) 1989-07-18
JP3133305B2 (ja) 2001-02-05
FI893474A7 (fi) 1989-07-18
DK354389D0 (da) 1989-07-18
JPH02502825A (ja) 1990-09-06
SE8902507L (sv) 1989-07-11
GR880100775A (el) 1994-03-31
PT89026A (pt) 1988-12-01
PT89026B (pt) 1993-02-26
DK354389A (da) 1989-09-19
FR2623400B1 (fr) 1995-06-23
GB8913271D0 (en) 1989-12-06
CH680001A5 (es) 1992-05-29
FR2623400A1 (fr) 1989-05-26
NZ226990A (en) 1991-10-25
HUT52551A (en) 1990-07-28
PL275881A1 (en) 1989-07-24
IL88404A0 (en) 1989-06-30
IT1224574B (it) 1990-10-04
KR890701625A (ko) 1989-12-21
US6383479B1 (en) 2002-05-07
IT8848572A0 (it) 1988-11-18
DE3890998B4 (de) 2008-01-03
AU622125B2 (en) 1992-04-02
GB2223225A (en) 1990-04-04
HU886790D0 (en) 1990-01-28
ATA901588A (de) 1994-07-15
SE8902507D0 (sv) 1989-07-11
DE3890998T1 (de) 1991-02-21
NL194982C (nl) 2003-04-10
AU2716288A (en) 1989-06-14
NL8820928A (nl) 1989-10-02

Similar Documents

Publication Publication Date Title
NO992353D0 (no) Rensing av neurotrofiner
NO307968B1 (no) Pyrazolo- og pyrrolopyridiner og farmasøytisk blanding derav
ATE114169T1 (de) Morphogenetisches knochenprotein.
DE69023073D1 (de) Herstellung von Vorrichtungen mittels lithographischer Prozesse.
ES2114786A1 (es) Tromboyetina. trombopoyetina recombinante y procedimiento de obtencion.
ATE315938T1 (de) 4'-substituierte nukleoside zur behandlung von hepatitis-c-virus-vermittelten erkrankungen
IT8721618A0 (it) Prodecimento per la depurazione bilogica di acque reflue.
BR9708114A (pt) Análogos xantona para o tratamento de doenças infecciosas.
DE59704288D1 (de) Verfahren zur Herstellung von Alpha,Omega-C4- bis C20-Alkenolen
PT88684A (pt) Metodo de tratamento fosfatidilico de doencas virais
FI931332A0 (fi) Uusia alkyleenidiammoniumdiklavulanaattijohdannaisia, menetelmä niidenvalmistamiseksi samoin kuin niiden käyttö kalvulaanihapon puhdistamiseksi
DE3776999D1 (de) Mittel zur vorbeugung gegen pflanzenviruskrankheiten.
DE3682811D1 (de) Pharmazeutische zusammensetzung zur heilung und verhuetung kardiovaskularer krankheiten und verfahren zu ihrer herstellung.
DE69110713D1 (de) 7-Oxabicycloheptan-imidazol-prostaglandin-Analoge, verwendbar bei der Behandlung von thrombotischen und vasospastischen Erkrankungen.
IT1231126B (it) Procedimento per la produzione di impiallacciatura artificiale ad imitazione della radica, mediante bruciature.
IT1276823B1 (it) Procedimento per la purificazione dell'acetone
ES2132419T3 (es) Nuevos agentes de nucleosidos 9-n-biciclicos utiles como inhibidores selectivos de citocinas proinflamatorias.
ITMI913465A1 (it) Procedimento per la depurazione dell'1, 1, 1-trifluoro-2-fluoroetano
IT7831100A0 (it) Procedimento per trattare fanghi, risultanti dalla depurazione di gas, in modo da renderli utilizzabili.
FI945322L (fi) Menetelmä 2',3'-didehydro-2',3'-dideoksinukleosidien laajamittaista valmistusta varten
BG102707A (bg) Нови триазолопурини, метод за тяхното получаване и тяхното приложение като лекарствени средства
IT1244560B (it) Procedimento impianto per il trattamento di depurazione, di fumi, polveri o gas di scarico dopo la combustione.
ATA265789A (de) Gasreinigungsanlage
DK1007527T3 (da) Optisk rene camptothecinanaloger, optisk rene syntesemellemprodukter og fremgangsmåde til fremstilling heraf
DK10188D0 (da) Middel til behandling af virussygdomme

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-11-18

FD1A Patent lapsed

Effective date: 20010402