ATE113312T1 - Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist. - Google Patents
Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist.Info
- Publication number
- ATE113312T1 ATE113312T1 AT89909925T AT89909925T ATE113312T1 AT E113312 T1 ATE113312 T1 AT E113312T1 AT 89909925 T AT89909925 T AT 89909925T AT 89909925 T AT89909925 T AT 89909925T AT E113312 T1 ATE113312 T1 AT E113312T1
- Authority
- AT
- Austria
- Prior art keywords
- chemotactic factor
- human neutrophil
- neutrophil chemotactic
- preparing
- polypeptide active
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title abstract 5
- 102000004890 Interleukin-8 Human genes 0.000 title abstract 5
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 229920002684 Sepharose Polymers 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 229960000789 guanidine hydrochloride Drugs 0.000 abstract 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5421—IL-8
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23774188A | 1988-08-29 | 1988-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE113312T1 true ATE113312T1 (de) | 1994-11-15 |
Family
ID=22894964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89909925T ATE113312T1 (de) | 1988-08-29 | 1989-08-29 | Verfahren zur herstellung eines polypeptids welches als menschlicher neutrophiler chemotaktischer faktor aktiv ist. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5401643A (de) |
| EP (1) | EP0431042B1 (de) |
| JP (1) | JP3053631B2 (de) |
| KR (1) | KR100197110B1 (de) |
| AT (1) | ATE113312T1 (de) |
| DE (1) | DE68919085T2 (de) |
| WO (1) | WO1990002178A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5652338A (en) | 1988-03-16 | 1997-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Neutrophil chemotactic factor |
| NZ541050A (en) | 2002-12-16 | 2010-06-25 | Genmab As | Human monoclonal antibodies against interleukin 8 (IL-8) |
| AU2006294868B2 (en) * | 2005-09-26 | 2011-03-03 | Coupons, Inc. | System and method for augmenting content in electronic documents with links to contextually relevant information |
| WO2019140150A1 (en) | 2018-01-12 | 2019-07-18 | Bristol-Myers Squibb Company | Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4511502A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| US4897348A (en) * | 1983-08-25 | 1990-01-30 | Sri International | Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof |
| DE3890998B4 (de) * | 1987-11-19 | 2008-01-03 | Novartis Ag | Neutrophilenaktivierungsfaktor, Verfahren zu seiner Herstellung und ihn enthaltende pharmazeutische Zusammensetzung |
| US5026639A (en) * | 1988-01-14 | 1991-06-25 | Nippon Mining Company, Limited | Method to improve mRNA translation and use thereof for production of platelet factor-4 |
-
1989
- 1989-08-29 AT AT89909925T patent/ATE113312T1/de not_active IP Right Cessation
- 1989-08-29 JP JP1509164A patent/JP3053631B2/ja not_active Expired - Lifetime
- 1989-08-29 KR KR1019900700891A patent/KR100197110B1/ko not_active Expired - Lifetime
- 1989-08-29 DE DE68919085T patent/DE68919085T2/de not_active Expired - Lifetime
- 1989-08-29 EP EP89909925A patent/EP0431042B1/de not_active Expired - Lifetime
- 1989-08-29 WO PCT/US1989/003728 patent/WO1990002178A1/en not_active Ceased
-
1992
- 1992-03-23 US US07/855,471 patent/US5401643A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3053631B2 (ja) | 2000-06-19 |
| DE68919085T2 (de) | 1995-04-06 |
| KR100197110B1 (ko) | 1999-06-15 |
| EP0431042A4 (en) | 1992-03-11 |
| EP0431042A1 (de) | 1991-06-12 |
| US5401643A (en) | 1995-03-28 |
| WO1990002178A1 (en) | 1990-03-08 |
| EP0431042B1 (de) | 1994-10-26 |
| KR900702031A (ko) | 1990-12-05 |
| JPH04500156A (ja) | 1992-01-16 |
| DE68919085D1 (de) | 1994-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |