ES2025665T3 - Un procedimiento para preparar polimorfo b de cimetidina. - Google Patents

Un procedimiento para preparar polimorfo b de cimetidina.

Info

Publication number
ES2025665T3
ES2025665T3 ES198787306730T ES87306730T ES2025665T3 ES 2025665 T3 ES2025665 T3 ES 2025665T3 ES 198787306730 T ES198787306730 T ES 198787306730T ES 87306730 T ES87306730 T ES 87306730T ES 2025665 T3 ES2025665 T3 ES 2025665T3
Authority
ES
Spain
Prior art keywords
cimetidine
procedure
preparing polymorph
polymorph
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787306730T
Other languages
English (en)
Inventor
Harold Graboyes
David Samuel Kirkpatrick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2025665T3 publication Critical patent/ES2025665T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

UN PROCEDIMIENTO NUEVO, PARA PREPARAR POLIMORFO "B" DE CIMETIDINA CONSISTE EN PRECIPITAR CIMETIDINA DE UNA SOLUCION HIDROALCOHOLICA DE UNA SAL OBTENIDA POR ADICION DE ACIDO. LA PRECIPITACION SE LLEVA A CABO A UNA TEMPERATURA SUPERIOR A LOS 18 GRADOS CENTIGRADOS.
ES198787306730T 1986-08-01 1987-07-29 Un procedimiento para preparar polimorfo b de cimetidina. Expired - Lifetime ES2025665T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868618846A GB8618846D0 (en) 1986-08-01 1986-08-01 Chemical process

Publications (1)

Publication Number Publication Date
ES2025665T3 true ES2025665T3 (es) 1992-04-01

Family

ID=10602096

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787306730T Expired - Lifetime ES2025665T3 (es) 1986-08-01 1987-07-29 Un procedimiento para preparar polimorfo b de cimetidina.

Country Status (19)

Country Link
US (1) US4786735A (es)
EP (1) EP0255376B1 (es)
JP (1) JPH0762002B2 (es)
KR (1) KR880002838A (es)
CN (1) CN87105393A (es)
AT (1) ATE68791T1 (es)
AU (1) AU604733B2 (es)
CA (1) CA1301767C (es)
CZ (1) CZ397491A3 (es)
DE (1) DE3774024D1 (es)
DK (1) DK163303C (es)
ES (1) ES2025665T3 (es)
FI (1) FI94633C (es)
GB (1) GB8618846D0 (es)
GR (1) GR3003253T3 (es)
IE (1) IE60415B1 (es)
NO (1) NO170975C (es)
PT (1) PT85435B (es)
ZA (1) ZA875675B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH064601B2 (ja) * 1987-11-04 1994-01-19 三井石油化学工業株式会社 Ｎ−シアノ−ｎ’−メチル−ｎ’’−［２−｛（５−メチル−１ｈ−イミダゾール−４−イル）メチルチオ｝エチルグアニジンの精製法
JPH07110514B2 (ja) * 1990-06-25 1995-11-29 積水化学工業株式会社 芯材強化樹脂軒樋の製造方法
US5808090A (en) * 1996-02-22 1998-09-15 Endo Pharmaceuticals Inc. Process for preventing precipitation in cimetidine injection solutions
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE60114889T2 (de) * 2001-03-23 2006-07-20 Richter Gedeon Vegyészeti Gyár R.T. Verfahren zur herstellung von fluconazole und kristallmodifikationen davon
BR0212833A (pt) 2001-09-26 2004-10-13 Baxter Int Preparação de nanopartìculas de tamanho submìcron através de dispersão e de remoção de solvente ou de fase lìquida
DE10349113A1 (de) 2003-10-17 2005-05-12 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Aminocrotonylverbindungen
US7741358B2 (en) * 2005-04-14 2010-06-22 N.V. Organon Crystal form of asenapine maleate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1543238A (en) * 1976-09-21 1979-03-28 Smith Kline French Lab Polymorph of cimetidine
JPS56104868A (en) * 1980-01-24 1981-08-20 Fujimoto Seiyaku Kk Conversion between polymorphous crystals of cimetidine
FI63753C (fi) * 1980-08-21 1987-02-19 Orion Yhtymae Oy Foerfarande foer framstaellning av kristallint simetidin.
HU185457B (en) * 1981-09-25 1985-02-28 Richter Gedeon Vegyeszet Process for preparating cimetidine-z
JPS58152868A (ja) * 1982-03-05 1983-09-10 Fujimoto Seiyaku Kk シメチジン１塩酸塩多形体およびその製造方法
IE55946B1 (en) * 1982-10-08 1991-02-27 Gea Farmaceutisk Fabrik As Thioethercyanoguanidines and their use as intermediates in producing imidazoles

Also Published As

Publication number Publication date
EP0255376A1 (en) 1988-02-03
IE60415B1 (en) 1994-07-13
PT85435A (en) 1987-08-01
NO170975C (no) 1993-01-06
CN87105393A (zh) 1988-02-17
JPH0762002B2 (ja) 1995-07-05
DK393087D0 (da) 1987-07-28
CZ397491A3 (en) 1993-08-11
FI94633C (fi) 1995-10-10
DE3774024D1 (de) 1991-11-28
GB8618846D0 (en) 1986-09-10
CA1301767C (en) 1992-05-26
IE872022L (en) 1988-02-01
FI873340A0 (fi) 1987-07-31
AU7625387A (en) 1988-02-04
FI873340L (fi) 1988-02-02
DK163303B (da) 1992-02-17
NO170975B (no) 1992-09-28
FI94633B (fi) 1995-06-30
KR880002838A (ko) 1988-05-11
EP0255376B1 (en) 1991-10-23
PT85435B (pt) 1990-06-29
GR3003253T3 (en) 1993-02-17
US4786735A (en) 1988-11-22
NO873209L (no) 1988-02-02
DK393087A (da) 1988-02-02
JPS6341465A (ja) 1988-02-22
DK163303C (da) 1992-07-06
NO873209D0 (no) 1987-07-31
ATE68791T1 (de) 1991-11-15
AU604733B2 (en) 1991-01-03
ZA875675B (en) 1988-11-30

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