ES2030106T3 - Procedimiento para preparar eteres propargilicos de compuestos hidroxiaromaticos. - Google Patents
Procedimiento para preparar eteres propargilicos de compuestos hidroxiaromaticos.Info
- Publication number
- ES2030106T3 ES2030106T3 ES198888108445T ES88108445T ES2030106T3 ES 2030106 T3 ES2030106 T3 ES 2030106T3 ES 198888108445 T ES198888108445 T ES 198888108445T ES 88108445 T ES88108445 T ES 88108445T ES 2030106 T3 ES2030106 T3 ES 2030106T3
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- compounds
- product
- propargilic
- hydroxiaromatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
- C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCESO PARA PREPARAR ETERES PROPARGILICOS, EN ESPECIAL ETER BIS-PROPARGILICO, A PARTIR DE COMPUESTOS HIDROXIAROMATICOS, QUE IMPLICA AGITAR VIGOROSAMENTE UN HALURO DE PROPARGILO, PREFERIBLEMENTE CLORURO DE PROPARGILO CON UN COMPUESTO HIDROXIAROMATICO, TAL COMO BISFENOL A EN UNA SOLUCION ACUOSA DE HIDROXIDO SODICO A UNA TEMPERATURA COMPRENDIDA ENTRE 0 Y 100 GRADOS C, EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASES TAL COMO BROMURO DE TETRABUTILAMONIO. LA MEZCLA SE FILTRA DESPUES PARA RECUPERAR UN PRODUCTO SOLIDO QUE SE LAVA CON AGUA Y PROPANOL. ESTE PROCESO PROPORCIONA UN PRODUCTO QUE TIENE MAS DEL 95% DE PUREZA CON UN RENDIMIENTO DE 85 A 97% DEL TEORICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5619087A | 1987-06-01 | 1987-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2030106T3 true ES2030106T3 (es) | 1992-10-16 |
Family
ID=22002778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888108445T Expired - Lifetime ES2030106T3 (es) | 1987-06-01 | 1988-05-27 | Procedimiento para preparar eteres propargilicos de compuestos hidroxiaromaticos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4885403A (es) |
| EP (1) | EP0293768B1 (es) |
| JP (1) | JPH01503541A (es) |
| KR (1) | KR910003821B1 (es) |
| AT (1) | ATE74344T1 (es) |
| AU (1) | AU605331B2 (es) |
| BR (1) | BR8807088A (es) |
| CA (1) | CA1318688C (es) |
| DE (1) | DE3869661D1 (es) |
| ES (1) | ES2030106T3 (es) |
| IL (1) | IL86547A0 (es) |
| NO (1) | NO890404D0 (es) |
| WO (1) | WO1988009782A1 (es) |
| ZA (1) | ZA883880B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68920609T2 (de) * | 1988-03-15 | 1995-08-17 | Nippon Paint Co Ltd | Aromatische allenische Verbindungen und ihre Herstellung. |
| US4987272A (en) * | 1989-07-28 | 1991-01-22 | Shell Oil Company | Dipropargyl ether of alpha, alpha'-bis (4-hydroxypenyl)-paradiisopropylbenzene |
| US5096987A (en) * | 1989-07-28 | 1992-03-17 | Shell Oil Company | Dipropargyl ether or alpha, alpha'-bis(4-hydroxyphenyl)-para-diisopropylbenzene |
| DE4123535A1 (de) * | 1991-07-16 | 1993-01-21 | Bayer Ag | Verfahren zur herstellung von propargylethern und neue propargylether |
| US5367043A (en) * | 1991-11-06 | 1994-11-22 | Enzymol International, Inc. | Durable formaldehyde-free phenolic resins, and method of preparing such resins |
| US5559189A (en) * | 1994-02-14 | 1996-09-24 | Easter Michigan University | Fast curing thermosetting acetylenic polymeric vehicle |
| US5556921A (en) * | 1994-02-14 | 1996-09-17 | Eastern Michigan University | Air dried cross-linkable polymeric vehicles which include acetylenic groups |
| US5475133A (en) * | 1994-11-28 | 1995-12-12 | The Regents Of The University Of California | Bis-propargyl thermosets |
| US5714086A (en) * | 1996-08-09 | 1998-02-03 | Quantum Materials, Inc. | Propargyl ether-containing compositions useful for underfill applications |
| FR2772372B1 (fr) * | 1997-12-15 | 2000-05-19 | Rhodia Chimie Sa | Procede de o-alkylation de composes aromatiques hydroxyles |
| US6767981B1 (en) | 2002-09-26 | 2004-07-27 | The United States Of America As Represented By The Secretary Of The Navy | Thermoset and ceramic containing silicon and boron |
| HUE034458T2 (en) | 2008-07-02 | 2018-02-28 | British Columbia Cancer Agency Branch | Diglycidyl ether derivatives, therapeutics and methods for their use |
| US9388112B2 (en) | 2010-01-06 | 2016-07-12 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| US9365510B2 (en) | 2012-04-16 | 2016-06-14 | British Columbia Cancer Agency Branch | Aziridine bisphenol ethers and related compounds and methods for their use |
| ES2957540T3 (es) | 2012-07-10 | 2024-01-22 | Massachusetts Gen Hospital | Sistema y método para monitorizar y tratar una superficie de un sujeto |
| AU2014262333B2 (en) | 2013-05-10 | 2016-06-16 | British Columbia Cancer Agency Branch | Ester derivatives of androgen receptor modulators and methods for their use |
| WO2015031984A1 (en) | 2013-09-09 | 2015-03-12 | British Columbia Cancer Agency Branch | Halogenated compounds for cancer imaging and treatment and methods for their use |
| DK3988541T3 (da) | 2015-01-13 | 2024-09-16 | British Columbia Cancer Agency Branch | Heterocycliske forbindelser til billedscanning og behandling af cancer samt fremgangsmåder til anvendelse af disse |
| WO2016141458A1 (en) | 2015-03-12 | 2016-09-15 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
| RU2616294C2 (ru) * | 2015-10-05 | 2017-04-14 | Федеральное казенное предприятие "Алексинский химический комбинат" (ФКП АХК) | Модифицированное связующее на основе новолачных и резольных смол и способ его изготовления |
| US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| US11485713B2 (en) | 2018-05-25 | 2022-11-01 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
| WO2020081999A1 (en) | 2018-10-18 | 2020-04-23 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
| WO2020198712A1 (en) | 2019-03-28 | 2020-10-01 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
| CN115916170A (zh) | 2020-04-17 | 2023-04-04 | 埃萨制药股份有限公司 | 固体形式的n-末端结构域雄激素受体抑制剂及其用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE841145C (de) * | 1950-07-23 | 1952-06-13 | Bayer Ag | Verfahren zur Herstellung des Dipropargylaethers des 4, 4'-Dioxy-ª‡, ª‰-diaethylstilbens |
| US3322813A (en) * | 1962-06-30 | 1967-05-30 | Meiji Seika Kaisha | Halopropargyl aryl ether compounds |
| GB1097255A (en) * | 1964-08-15 | 1968-01-03 | Fisons Pest Control Ltd | Propargyloxybenzene derivatives and their use as pesticides |
| GB1274973A (en) * | 1969-03-03 | 1972-05-17 | Nagase & Co Ltd | Acetylene derivatives |
| US3686331A (en) * | 1969-05-28 | 1972-08-22 | Hoffmann La Roche | Anti-microbial phenyl 3-halopropargyl ethers |
| US3830849A (en) * | 1969-11-26 | 1974-08-20 | Ciba Geigy Ag | Propargyl ethers |
| US3950328A (en) * | 1970-10-20 | 1976-04-13 | Ciba-Geigy Corporation | New terpene aryl ethers |
| US4141921A (en) * | 1972-02-09 | 1979-02-27 | Ciba-Geigy Corporation | Phenoxyphenyl- and phenoxybenzyl-alkynyl ethers |
| US3896042A (en) * | 1974-02-15 | 1975-07-22 | Us Energy | Low temperature, low pressure hydrogen gettering |
| JPS5944315B2 (ja) * | 1977-12-28 | 1984-10-29 | 大塚化学薬品株式会社 | 2−ペンチニルエ−テルの製造法 |
| CH643223A5 (it) * | 1978-06-21 | 1984-05-30 | Montedison Spa | Dieteri idrochinonici aventi attivita ormonica giovanile e acaricida. |
| US4540711A (en) * | 1978-06-21 | 1985-09-10 | Montedison S.P.A. | Method for combatting infestations of insects and acari, and compositions for use in said method |
| CA1104589A (en) * | 1978-06-27 | 1981-07-07 | Rudolf Wehrli | Alcohols |
| FR2442822A1 (fr) * | 1978-11-30 | 1980-06-27 | Rhone Poulenc Agrochimie | Procede de preparation d'ethers insatures |
| US4226800A (en) * | 1979-06-14 | 1980-10-07 | The United States Of America As Represented By The Secretary Of The Air Force | Synthesis of acetylene-terminated compounds |
| US4433179A (en) * | 1980-08-25 | 1984-02-21 | Ciba-Geigy Corporation | Process for the preparation of di- and poly-allyl ethers |
| IT1190714B (it) * | 1982-03-04 | 1988-02-24 | Montedison Spa | Processo per la preparazione del composto 1-decilossi-4-((7-ossa-4-ottinil)-ossi)-benzene |
| US4613703A (en) * | 1982-04-05 | 1986-09-23 | The Dow Chemical Company | Process for allylating hydroxyaromatic compounds |
| IL69304A0 (en) * | 1982-08-23 | 1983-11-30 | American Cyanamid Co | Method for the preparation of difluoromethoxyaromatic compounds |
-
1988
- 1988-05-25 KR KR1019890700179A patent/KR910003821B1/ko not_active Expired
- 1988-05-25 AU AU19366/88A patent/AU605331B2/en not_active Ceased
- 1988-05-25 JP JP63504942A patent/JPH01503541A/ja active Pending
- 1988-05-25 WO PCT/US1988/001734 patent/WO1988009782A1/en not_active Ceased
- 1988-05-25 BR BR888807088A patent/BR8807088A/pt unknown
- 1988-05-27 EP EP88108445A patent/EP0293768B1/en not_active Expired - Lifetime
- 1988-05-27 ES ES198888108445T patent/ES2030106T3/es not_active Expired - Lifetime
- 1988-05-27 AT AT88108445T patent/ATE74344T1/de not_active IP Right Cessation
- 1988-05-27 DE DE8888108445T patent/DE3869661D1/de not_active Expired - Fee Related
- 1988-05-30 IL IL86547A patent/IL86547A0/xx unknown
- 1988-05-31 CA CA000568197A patent/CA1318688C/en not_active Expired - Fee Related
- 1988-06-01 ZA ZA883880A patent/ZA883880B/xx unknown
- 1988-07-29 US US07/225,699 patent/US4885403A/en not_active Expired - Fee Related
-
1989
- 1989-01-31 NO NO890404A patent/NO890404D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01503541A (ja) | 1989-11-30 |
| EP0293768B1 (en) | 1992-04-01 |
| IL86547A0 (en) | 1988-11-15 |
| KR890701519A (ko) | 1989-12-20 |
| US4885403A (en) | 1989-12-05 |
| NO890404L (no) | 1989-01-31 |
| KR910003821B1 (ko) | 1991-06-12 |
| AU1936688A (en) | 1989-01-04 |
| NO890404D0 (no) | 1989-01-31 |
| CA1318688C (en) | 1993-06-01 |
| EP0293768A1 (en) | 1988-12-07 |
| WO1988009782A1 (en) | 1988-12-15 |
| ATE74344T1 (de) | 1992-04-15 |
| DE3869661D1 (de) | 1992-05-07 |
| BR8807088A (pt) | 1989-10-17 |
| AU605331B2 (en) | 1991-01-10 |
| ZA883880B (en) | 1990-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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