ATE74344T1 - Verfahren zur herstellung von propargylaethern von hydroxyaromatischen verbindungen. - Google Patents
Verfahren zur herstellung von propargylaethern von hydroxyaromatischen verbindungen.Info
- Publication number
- ATE74344T1 ATE74344T1 AT88108445T AT88108445T ATE74344T1 AT E74344 T1 ATE74344 T1 AT E74344T1 AT 88108445 T AT88108445 T AT 88108445T AT 88108445 T AT88108445 T AT 88108445T AT E74344 T1 ATE74344 T1 AT E74344T1
- Authority
- AT
- Austria
- Prior art keywords
- product
- propargyl
- hydroxyaromatic compounds
- propargylaethers
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- HRDCVMSNCBAMAM-UHFFFAOYSA-N 3-prop-2-ynoxyprop-1-yne Chemical compound C#CCOCC#C HRDCVMSNCBAMAM-UHFFFAOYSA-N 0.000 abstract 2
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- -1 propargyl halide Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- LJZPPWWHKPGCHS-UHFFFAOYSA-N propargyl chloride Chemical compound ClCC#C LJZPPWWHKPGCHS-UHFFFAOYSA-N 0.000 abstract 1
- 239000012265 solid product Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- JRMUNVKIHCOMHV-UHFFFAOYSA-M tetrabutylammonium bromide Chemical compound [Br-].CCCC[N+](CCCC)(CCCC)CCCC JRMUNVKIHCOMHV-UHFFFAOYSA-M 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
- C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5619087A | 1987-06-01 | 1987-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE74344T1 true ATE74344T1 (de) | 1992-04-15 |
Family
ID=22002778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88108445T ATE74344T1 (de) | 1987-06-01 | 1988-05-27 | Verfahren zur herstellung von propargylaethern von hydroxyaromatischen verbindungen. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4885403A (de) |
| EP (1) | EP0293768B1 (de) |
| JP (1) | JPH01503541A (de) |
| KR (1) | KR910003821B1 (de) |
| AT (1) | ATE74344T1 (de) |
| AU (1) | AU605331B2 (de) |
| BR (1) | BR8807088A (de) |
| CA (1) | CA1318688C (de) |
| DE (1) | DE3869661D1 (de) |
| ES (1) | ES2030106T3 (de) |
| IL (1) | IL86547A0 (de) |
| NO (1) | NO890404D0 (de) |
| WO (1) | WO1988009782A1 (de) |
| ZA (1) | ZA883880B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68920609T2 (de) * | 1988-03-15 | 1995-08-17 | Nippon Paint Co Ltd | Aromatische allenische Verbindungen und ihre Herstellung. |
| US4987272A (en) * | 1989-07-28 | 1991-01-22 | Shell Oil Company | Dipropargyl ether of alpha, alpha'-bis (4-hydroxypenyl)-paradiisopropylbenzene |
| US5096987A (en) * | 1989-07-28 | 1992-03-17 | Shell Oil Company | Dipropargyl ether or alpha, alpha'-bis(4-hydroxyphenyl)-para-diisopropylbenzene |
| DE4123535A1 (de) * | 1991-07-16 | 1993-01-21 | Bayer Ag | Verfahren zur herstellung von propargylethern und neue propargylether |
| US5367043A (en) * | 1991-11-06 | 1994-11-22 | Enzymol International, Inc. | Durable formaldehyde-free phenolic resins, and method of preparing such resins |
| US5559189A (en) * | 1994-02-14 | 1996-09-24 | Easter Michigan University | Fast curing thermosetting acetylenic polymeric vehicle |
| US5556921A (en) * | 1994-02-14 | 1996-09-17 | Eastern Michigan University | Air dried cross-linkable polymeric vehicles which include acetylenic groups |
| US5475133A (en) * | 1994-11-28 | 1995-12-12 | The Regents Of The University Of California | Bis-propargyl thermosets |
| US5714086A (en) * | 1996-08-09 | 1998-02-03 | Quantum Materials, Inc. | Propargyl ether-containing compositions useful for underfill applications |
| FR2772372B1 (fr) * | 1997-12-15 | 2000-05-19 | Rhodia Chimie Sa | Procede de o-alkylation de composes aromatiques hydroxyles |
| US6767981B1 (en) | 2002-09-26 | 2004-07-27 | The United States Of America As Represented By The Secretary Of The Navy | Thermoset and ceramic containing silicon and boron |
| HUE034458T2 (en) | 2008-07-02 | 2018-02-28 | British Columbia Cancer Agency Branch | Diglycidyl ether derivatives, therapeutics and methods for their use |
| US9388112B2 (en) | 2010-01-06 | 2016-07-12 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| US9365510B2 (en) | 2012-04-16 | 2016-06-14 | British Columbia Cancer Agency Branch | Aziridine bisphenol ethers and related compounds and methods for their use |
| ES2957540T3 (es) | 2012-07-10 | 2024-01-22 | Massachusetts Gen Hospital | Sistema y método para monitorizar y tratar una superficie de un sujeto |
| AU2014262333B2 (en) | 2013-05-10 | 2016-06-16 | British Columbia Cancer Agency Branch | Ester derivatives of androgen receptor modulators and methods for their use |
| WO2015031984A1 (en) | 2013-09-09 | 2015-03-12 | British Columbia Cancer Agency Branch | Halogenated compounds for cancer imaging and treatment and methods for their use |
| DK3988541T3 (da) | 2015-01-13 | 2024-09-16 | British Columbia Cancer Agency Branch | Heterocycliske forbindelser til billedscanning og behandling af cancer samt fremgangsmåder til anvendelse af disse |
| WO2016141458A1 (en) | 2015-03-12 | 2016-09-15 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
| RU2616294C2 (ru) * | 2015-10-05 | 2017-04-14 | Федеральное казенное предприятие "Алексинский химический комбинат" (ФКП АХК) | Модифицированное связующее на основе новолачных и резольных смол и способ его изготовления |
| US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| US11485713B2 (en) | 2018-05-25 | 2022-11-01 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
| WO2020081999A1 (en) | 2018-10-18 | 2020-04-23 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
| WO2020198712A1 (en) | 2019-03-28 | 2020-10-01 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
| CN115916170A (zh) | 2020-04-17 | 2023-04-04 | 埃萨制药股份有限公司 | 固体形式的n-末端结构域雄激素受体抑制剂及其用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE841145C (de) * | 1950-07-23 | 1952-06-13 | Bayer Ag | Verfahren zur Herstellung des Dipropargylaethers des 4, 4'-Dioxy-ª‡, ª‰-diaethylstilbens |
| US3322813A (en) * | 1962-06-30 | 1967-05-30 | Meiji Seika Kaisha | Halopropargyl aryl ether compounds |
| GB1097255A (en) * | 1964-08-15 | 1968-01-03 | Fisons Pest Control Ltd | Propargyloxybenzene derivatives and their use as pesticides |
| GB1274973A (en) * | 1969-03-03 | 1972-05-17 | Nagase & Co Ltd | Acetylene derivatives |
| US3686331A (en) * | 1969-05-28 | 1972-08-22 | Hoffmann La Roche | Anti-microbial phenyl 3-halopropargyl ethers |
| US3830849A (en) * | 1969-11-26 | 1974-08-20 | Ciba Geigy Ag | Propargyl ethers |
| US3950328A (en) * | 1970-10-20 | 1976-04-13 | Ciba-Geigy Corporation | New terpene aryl ethers |
| US4141921A (en) * | 1972-02-09 | 1979-02-27 | Ciba-Geigy Corporation | Phenoxyphenyl- and phenoxybenzyl-alkynyl ethers |
| US3896042A (en) * | 1974-02-15 | 1975-07-22 | Us Energy | Low temperature, low pressure hydrogen gettering |
| JPS5944315B2 (ja) * | 1977-12-28 | 1984-10-29 | 大塚化学薬品株式会社 | ２−ペンチニルエ−テルの製造法 |
| CH643223A5 (it) * | 1978-06-21 | 1984-05-30 | Montedison Spa | Dieteri idrochinonici aventi attivita ormonica giovanile e acaricida. |
| US4540711A (en) * | 1978-06-21 | 1985-09-10 | Montedison S.P.A. | Method for combatting infestations of insects and acari, and compositions for use in said method |
| CA1104589A (en) * | 1978-06-27 | 1981-07-07 | Rudolf Wehrli | Alcohols |
| FR2442822A1 (fr) * | 1978-11-30 | 1980-06-27 | Rhone Poulenc Agrochimie | Procede de preparation d'ethers insatures |
| US4226800A (en) * | 1979-06-14 | 1980-10-07 | The United States Of America As Represented By The Secretary Of The Air Force | Synthesis of acetylene-terminated compounds |
| US4433179A (en) * | 1980-08-25 | 1984-02-21 | Ciba-Geigy Corporation | Process for the preparation of di- and poly-allyl ethers |
| IT1190714B (it) * | 1982-03-04 | 1988-02-24 | Montedison Spa | Processo per la preparazione del composto 1-decilossi-4-((7-ossa-4-ottinil)-ossi)-benzene |
| US4613703A (en) * | 1982-04-05 | 1986-09-23 | The Dow Chemical Company | Process for allylating hydroxyaromatic compounds |
| IL69304A0 (en) * | 1982-08-23 | 1983-11-30 | American Cyanamid Co | Method for the preparation of difluoromethoxyaromatic compounds |
-
1988
- 1988-05-25 KR KR1019890700179A patent/KR910003821B1/ko not_active Expired
- 1988-05-25 AU AU19366/88A patent/AU605331B2/en not_active Ceased
- 1988-05-25 JP JP63504942A patent/JPH01503541A/ja active Pending
- 1988-05-25 WO PCT/US1988/001734 patent/WO1988009782A1/en not_active Ceased
- 1988-05-25 BR BR888807088A patent/BR8807088A/pt unknown
- 1988-05-27 EP EP88108445A patent/EP0293768B1/de not_active Expired - Lifetime
- 1988-05-27 ES ES198888108445T patent/ES2030106T3/es not_active Expired - Lifetime
- 1988-05-27 AT AT88108445T patent/ATE74344T1/de not_active IP Right Cessation
- 1988-05-27 DE DE8888108445T patent/DE3869661D1/de not_active Expired - Fee Related
- 1988-05-30 IL IL86547A patent/IL86547A0/xx unknown
- 1988-05-31 CA CA000568197A patent/CA1318688C/en not_active Expired - Fee Related
- 1988-06-01 ZA ZA883880A patent/ZA883880B/xx unknown
- 1988-07-29 US US07/225,699 patent/US4885403A/en not_active Expired - Fee Related
-
1989
- 1989-01-31 NO NO890404A patent/NO890404D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01503541A (ja) | 1989-11-30 |
| EP0293768B1 (de) | 1992-04-01 |
| IL86547A0 (en) | 1988-11-15 |
| KR890701519A (ko) | 1989-12-20 |
| ES2030106T3 (es) | 1992-10-16 |
| US4885403A (en) | 1989-12-05 |
| NO890404L (no) | 1989-01-31 |
| KR910003821B1 (ko) | 1991-06-12 |
| AU1936688A (en) | 1989-01-04 |
| NO890404D0 (no) | 1989-01-31 |
| CA1318688C (en) | 1993-06-01 |
| EP0293768A1 (de) | 1988-12-07 |
| WO1988009782A1 (en) | 1988-12-15 |
| DE3869661D1 (de) | 1992-05-07 |
| BR8807088A (pt) | 1989-10-17 |
| AU605331B2 (en) | 1991-01-10 |
| ZA883880B (en) | 1990-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |