ES2038763T3 - Un procedimiento para producir una preparacion de antraciclina estabilizada. - Google Patents

Un procedimiento para producir una preparacion de antraciclina estabilizada.

Info

Publication number
ES2038763T3
ES2038763T3 ES198888307214T ES88307214T ES2038763T3 ES 2038763 T3 ES2038763 T3 ES 2038763T3 ES 198888307214 T ES198888307214 T ES 198888307214T ES 88307214 T ES88307214 T ES 88307214T ES 2038763 T3 ES2038763 T3 ES 2038763T3
Authority
ES
Spain
Prior art keywords
preparation
anthracicline
stabilized
procedure
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888307214T
Other languages
English (en)
Inventor
Yasuhisa Sakamaki
Yukio Ozaki
Tanno Norihiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2038763T3 publication Critical patent/ES2038763T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PREPARADO ESTABLE,EN PARTICULAR UNA INYECCION EN SECO POR CONGELACION, POR EJEMPLO DE (7S, 9S) - 9ACETIL - 9 - AMINO - 7 [(2 - DEOXI - BETA - D - ERITRO - PENTAPIRANOSIL)OXI] - 7, 8, 9, 10 - TETRAHIDRO - 6, 11 - DIHIDROXI - NAFTACENO - 5, 12 - DIONA O SUS SALES, QUE INCLUYE L - CISTEINA O SALES DERIVADAS.
ES198888307214T 1987-08-05 1988-08-04 Un procedimiento para producir una preparacion de antraciclina estabilizada. Expired - Lifetime ES2038763T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62197032A JP2603480B2 (ja) 1987-08-05 1987-08-05 安定化されたアンスラサイクリン系製剤

Publications (1)

Publication Number Publication Date
ES2038763T3 true ES2038763T3 (es) 1993-08-01

Family

ID=16367605

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888307214T Expired - Lifetime ES2038763T3 (es) 1987-08-05 1988-08-04 Un procedimiento para producir una preparacion de antraciclina estabilizada.

Country Status (14)

Country Link
US (1) US4952566A (es)
EP (1) EP0302729B1 (es)
JP (1) JP2603480B2 (es)
KR (1) KR970000507B1 (es)
AT (1) ATE71526T1 (es)
AU (1) AU609168B2 (es)
CA (1) CA1324959C (es)
DE (1) DE3867751D1 (es)
DK (1) DK173317B1 (es)
ES (1) ES2038763T3 (es)
FI (1) FI91483C (es)
GR (1) GR3004330T3 (es)
NO (1) NO175134C (es)
NZ (1) NZ225654A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222489B1 (hu) * 1990-07-25 2003-07-28 Novartis Ag. Stabilizált gyógyszerkészítmények és eljárás az előállításukra
US6300361B1 (en) 1990-07-25 2001-10-09 Novartis Ag Stabilized pharmaceutical compositions comprising acid donors
FR2665834B1 (fr) * 1991-07-24 2001-02-23 Sandoz Sa Composition pharmaceutique stabilisee par un donneur d'acide chlorhydrique, et sa preparation.
DE19741715A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
EP1034181B1 (en) * 1997-11-28 2006-01-11 Dainippon Sumitomo Pharma Co., Ltd. Crystalline amrubicin hydrochloride
CN1293088C (zh) * 2001-10-23 2007-01-03 住友化学工业株式会社 盐酸氨柔比星的稳定化
AU2003284478A1 (en) * 2002-11-29 2004-06-23 Sumitomo Pharmaceuticals Co., Ltd. Freeze-dried preparation of stabilized anthracycline compound
CN100395255C (zh) * 2005-02-02 2008-06-18 江苏豪森药业股份有限公司 马来酸氨柔比星盐及其制备方法和用途
BRPI0605832A2 (pt) * 2005-05-11 2009-05-26 Sicor Inc glicosìdeos de antraciclina liofilizados estáveis
ES2524700T3 (es) * 2009-05-27 2014-12-11 Sumitomo Dainippon Pharma Co., Ltd. Formulación estabilizada y liofilizada de compuestos de antraciclina
HK1216016A1 (zh) * 2012-12-19 2016-10-07 Colgate-Palmolive Company 鋅氨基酸絡合物與半胱氨酸
WO2016024369A1 (ja) * 2014-08-13 2016-02-18 テバ製薬株式会社 がん治療用医薬組成物
WO2019094819A2 (en) * 2017-11-09 2019-05-16 Abon Pharmaceuticals, Llc Intravenous delivery systems for chemotherapy drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2522187C2 (de) * 1975-05-17 1977-10-28 Byk Gulden Lomberg Chem Fab Verwendung von Cystein oder dessen Säureadditionssalz und Natriumdisulfit zur Stabilisierung von injizierbaren, einen pH-Wert zwischen 7 und 9 aufweisenden, Vitamin B tief 12 und nichtsteroidal Entzündungshemmer enthaltenden Arzneimitteln
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
JPS5976099A (ja) * 1982-10-22 1984-04-28 Sumitomo Chem Co Ltd アミノナフタセン誘導体とその製造方法
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions

Also Published As

Publication number Publication date
AU609168B2 (en) 1991-04-26
EP0302729B1 (en) 1992-01-15
FI883602A0 (fi) 1988-08-01
FI91483C (fi) 1994-07-11
CA1324959C (en) 1993-12-07
AU2042188A (en) 1989-02-09
ATE71526T1 (de) 1992-02-15
DK436688D0 (da) 1988-08-04
NO883447D0 (no) 1988-08-03
JPS6440493A (en) 1989-02-10
DE3867751D1 (de) 1992-02-27
JP2603480B2 (ja) 1997-04-23
DK436688A (da) 1989-02-06
DK173317B1 (da) 2000-07-17
GR3004330T3 (es) 1993-03-31
NO175134C (no) 1994-09-07
EP0302729A1 (en) 1989-02-08
NZ225654A (en) 1991-03-26
NO883447L (no) 1989-02-06
FI883602L (fi) 1989-02-06
NO175134B (no) 1994-05-30
KR970000507B1 (ko) 1997-01-13
FI91483B (fi) 1994-03-31
US4952566A (en) 1990-08-28
KR890003791A (ko) 1989-04-18

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