NO883447L - Stabilisert antracyklinpreparat. - Google Patents
Stabilisert antracyklinpreparat.Info
- Publication number
- NO883447L NO883447L NO88883447A NO883447A NO883447L NO 883447 L NO883447 L NO 883447L NO 88883447 A NO88883447 A NO 88883447A NO 883447 A NO883447 A NO 883447A NO 883447 L NO883447 L NO 883447L
- Authority
- NO
- Norway
- Prior art keywords
- stabilized
- preparation
- antracycline
- salts
- pentopyranosyl
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 235000013878 L-cysteine Nutrition 0.000 abstract 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- VJZITPJGSQKZMX-XDPRQOKASA-N amrubicin Chemical compound O([C@H]1C[C@](CC2=C(O)C=3C(=O)C4=CC=CC=C4C(=O)C=3C(O)=C21)(N)C(=O)C)[C@H]1C[C@H](O)[C@H](O)CO1 VJZITPJGSQKZMX-XDPRQOKASA-N 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62197032A JP2603480B2 (ja) | 1987-08-05 | 1987-08-05 | 安定化されたアンスラサイクリン系製剤 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO883447D0 NO883447D0 (no) | 1988-08-03 |
| NO883447L true NO883447L (no) | 1989-02-06 |
| NO175134B NO175134B (no) | 1994-05-30 |
| NO175134C NO175134C (no) | 1994-09-07 |
Family
ID=16367605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO883447A NO175134C (no) | 1987-08-05 | 1988-08-03 | Fremgangsmåte for fremstilling av et frysetörket injeksjonspreparat av (7S,9S)-9-acetyl-9-amino-7-[(2-deoksy- tro-pentopyranosyl)oksyÅ-7,8,9,10-tetrahydro-6,11-dihydroksy-naftacen-5,12-dion eller salter derav |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4952566A (no) |
| EP (1) | EP0302729B1 (no) |
| JP (1) | JP2603480B2 (no) |
| KR (1) | KR970000507B1 (no) |
| AT (1) | ATE71526T1 (no) |
| AU (1) | AU609168B2 (no) |
| CA (1) | CA1324959C (no) |
| DE (1) | DE3867751D1 (no) |
| DK (1) | DK173317B1 (no) |
| ES (1) | ES2038763T3 (no) |
| FI (1) | FI91483C (no) |
| GR (1) | GR3004330T3 (no) |
| NO (1) | NO175134C (no) |
| NZ (1) | NZ225654A (no) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6300362B1 (en) | 1990-07-25 | 2001-10-09 | Novartis Ag (Formerly Sandoz Ltd.) | Stabilized pharmaceutical compositions comprising acid donors |
| HU222489B1 (hu) * | 1990-07-25 | 2003-07-28 | Novartis Ag. | Stabilizált gyógyszerkészítmények és eljárás az előállításukra |
| FR2665834B1 (fr) * | 1991-07-24 | 2001-02-23 | Sandoz Sa | Composition pharmaceutique stabilisee par un donneur d'acide chlorhydrique, et sa preparation. |
| DE19741715A1 (de) * | 1997-09-22 | 1999-03-25 | Hoechst Ag | Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung |
| WO1999028331A2 (en) * | 1997-11-28 | 1999-06-10 | Sumitomo Pharmaceuticals Co., Ltd. | Crystalline amrubicin hydrochloride |
| WO2003035660A1 (en) * | 2001-10-23 | 2003-05-01 | Sumitomo Chemical Company, Limited | Stabilization of amrubicin hydrochloride |
| JP4594736B2 (ja) * | 2002-11-29 | 2010-12-08 | 大日本住友製薬株式会社 | 安定化されたアンスラサイクリン系化合物の凍結乾燥製剤 |
| CN100395255C (zh) * | 2005-02-02 | 2008-06-18 | 江苏豪森药业股份有限公司 | 马来酸氨柔比星盐及其制备方法和用途 |
| KR20070088447A (ko) * | 2005-05-11 | 2007-08-29 | 시코르, 인크. | 안정한 동결건조된 안트라사이클린 글리코시드 |
| DK2436386T3 (en) | 2009-05-27 | 2014-12-15 | Sumitomo Dainippon Pharma Co Ltd | A stabilized and lyophilized formulation of the anthracycline compounds |
| BR112015014478A2 (pt) * | 2012-12-19 | 2017-07-11 | Colgate Palmolive Co | complexo de haleto de aminoácido e zinco com cisteína |
| WO2016024369A1 (ja) * | 2014-08-13 | 2016-02-18 | テバ製薬株式会社 | がん治療用医薬組成物 |
| WO2019094819A2 (en) * | 2017-11-09 | 2019-05-16 | Abon Pharmaceuticals, Llc | Intravenous delivery systems for chemotherapy drugs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2522187C2 (de) * | 1975-05-17 | 1977-10-28 | Byk Gulden Lomberg Chem Fab | Verwendung von Cystein oder dessen Säureadditionssalz und Natriumdisulfit zur Stabilisierung von injizierbaren, einen pH-Wert zwischen 7 und 9 aufweisenden, Vitamin B tief 12 und nichtsteroidal Entzündungshemmer enthaltenden Arzneimitteln |
| US4540695A (en) * | 1981-08-12 | 1985-09-10 | Sumitomo Chemical Co., Ltd. | Aminonaphthacene derivatives and their use |
| JPS5976099A (ja) * | 1982-10-22 | 1984-04-28 | Sumitomo Chem Co Ltd | アミノナフタセン誘導体とその製造方法 |
| GB8426672D0 (en) * | 1984-10-22 | 1984-11-28 | Erba Farmitalia | Pharmaceutical compositions |
-
1987
- 1987-08-05 JP JP62197032A patent/JP2603480B2/ja not_active Expired - Lifetime
-
1988
- 1988-08-01 FI FI883602A patent/FI91483C/fi not_active IP Right Cessation
- 1988-08-02 US US07/227,135 patent/US4952566A/en not_active Expired - Lifetime
- 1988-08-02 NZ NZ225654A patent/NZ225654A/en unknown
- 1988-08-03 NO NO883447A patent/NO175134C/no not_active IP Right Cessation
- 1988-08-04 EP EP88307214A patent/EP0302729B1/en not_active Expired - Lifetime
- 1988-08-04 DK DK198804366A patent/DK173317B1/da not_active IP Right Cessation
- 1988-08-04 AU AU20421/88A patent/AU609168B2/en not_active Expired
- 1988-08-04 ES ES198888307214T patent/ES2038763T3/es not_active Expired - Lifetime
- 1988-08-04 AT AT88307214T patent/ATE71526T1/de not_active IP Right Cessation
- 1988-08-04 KR KR1019880009960A patent/KR970000507B1/ko not_active Expired - Lifetime
- 1988-08-04 DE DE8888307214T patent/DE3867751D1/de not_active Expired - Lifetime
- 1988-08-05 CA CA000574065A patent/CA1324959C/en not_active Expired - Lifetime
-
1992
- 1992-04-10 GR GR920400681T patent/GR3004330T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO175134B (no) | 1994-05-30 |
| KR970000507B1 (ko) | 1997-01-13 |
| KR890003791A (ko) | 1989-04-18 |
| EP0302729B1 (en) | 1992-01-15 |
| AU609168B2 (en) | 1991-04-26 |
| FI91483B (fi) | 1994-03-31 |
| JP2603480B2 (ja) | 1997-04-23 |
| ES2038763T3 (es) | 1993-08-01 |
| NO175134C (no) | 1994-09-07 |
| FI883602L (fi) | 1989-02-06 |
| AU2042188A (en) | 1989-02-09 |
| FI883602A0 (fi) | 1988-08-01 |
| DK436688D0 (da) | 1988-08-04 |
| DK173317B1 (da) | 2000-07-17 |
| CA1324959C (en) | 1993-12-07 |
| DK436688A (da) | 1989-02-06 |
| FI91483C (fi) | 1994-07-11 |
| ATE71526T1 (de) | 1992-02-15 |
| NO883447D0 (no) | 1988-08-03 |
| DE3867751D1 (de) | 1992-02-27 |
| US4952566A (en) | 1990-08-28 |
| NZ225654A (en) | 1991-03-26 |
| JPS6440493A (en) | 1989-02-10 |
| GR3004330T3 (no) | 1993-03-31 |
| EP0302729A1 (en) | 1989-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |