ES2040744T3 - Un procedimiento para preparar derivados de 1,2,4-triazinona. - Google Patents

Un procedimiento para preparar derivados de 1,2,4-triazinona.

Info

Publication number
ES2040744T3
ES2040744T3 ES198787302443T ES87302443T ES2040744T3 ES 2040744 T3 ES2040744 T3 ES 2040744T3 ES 198787302443 T ES198787302443 T ES 198787302443T ES 87302443 T ES87302443 T ES 87302443T ES 2040744 T3 ES2040744 T3 ES 2040744T3
Authority
ES
Spain
Prior art keywords
group
preparing
procedure
formula
triazinone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787302443T
Other languages
English (en)
Inventor
Yasuhiro Morisawa
Mitsuru Kataoka
Hitoshi Nagahori
Yasuo Shimoji
Fujio Saito
Mitsuo Sugiyama
Hiroyuki Koike
Takeshi Oshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7599686A external-priority patent/JPH0717618B2/ja
Priority claimed from JP61085255A external-priority patent/JPH0745478B2/ja
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2040744T3 publication Critical patent/ES2040744T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LOS COMPUESTOS DE FORMULA (I), (EN LA QUE: R1 ES H O ALQUILO; R2 PUEDE SER UNA VARIEDAD DE GRUPOS O ATOMOS; R3 ES OH OPCIONALMENTE SUSTITUIDO O -(NH)N-NR5R6 EN QUE R5 Y R6 SON DIFERENTES GRUPOS O ATOMOS, PREFERIBLEMENTE ALQUILO SUSTITUIDO POR HETEROCICLOS, Y N ES 0 O 1; Q ES OXIGENO O AZUFRE; Y A ES UN GRUPO ALQUILENO DE HASTA 6C), TIENEN ACTIVIDAD CARDIOTONICA VALIOSA Y PUEDEN EMPLEARSE PARA EL TRATAMIENTO DE DESORDENES CARDIACOS. SE PUEDEN PREPARAR A PARTIR DE LOS COMPUESTOS CORRESPONDIENTES QUE CONTIENEN UN ANILLO BENCENICO CON UN GRUPO -OH EN LA POSICION -1 Y UN GRUPO -CO-CHR1-NH-COOR7 EN LA POSICION -4 POR CIERRE DEL ANILLO E INTRODUCCION DEL GRUPO DE FORMULA -A-CO-R3 EN CUALQUIER ORDEN.
ES198787302443T 1986-03-20 1987-03-20 Un procedimiento para preparar derivados de 1,2,4-triazinona. Expired - Lifetime ES2040744T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6259386 1986-03-20
JP7599686A JPH0717618B2 (ja) 1986-04-02 1986-04-02 １，２，４−トリアジノン化合物
JP61085255A JPH0745478B2 (ja) 1986-04-14 1986-04-14 ヘテロ環状化合物

Publications (1)

Publication Number Publication Date
ES2040744T3 true ES2040744T3 (es) 1993-11-01

Family

ID=27297888

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787302443T Expired - Lifetime ES2040744T3 (es) 1986-03-20 1987-03-20 Un procedimiento para preparar derivados de 1,2,4-triazinona.

Country Status (5)

Country Link
US (1) US4898862A (es)
EP (1) EP0238357B1 (es)
KR (1) KR930003852B1 (es)
DE (1) DE3770299D1 (es)
ES (1) ES2040744T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5175161A (en) * 1989-04-06 1992-12-29 Sankyo Company, Limited Occular hypotensive agents
US5273976A (en) * 1989-04-06 1993-12-28 Sankyo Company, Limited Ocular hypotensive agents
DE4239540A1 (de) * 1992-11-25 1994-05-26 Asta Medica Ag Neue heterocyclische Verbindungen mit antiasthmatischer/antiallergischer, entzündungshemmender, positiv inotroper und blutdrucksenkender Wirkung
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172252D1 (en) * 1980-11-14 1985-10-17 Ici Plc Heterocyclic compounds
ZA827641B (en) * 1981-11-12 1983-09-28 Ici Plc Thiadiazine, oxadiazine and triazine derivatives which possess cardiotonic and/or antihypertensive activity
GB8310435D0 (en) * 1983-04-18 1983-05-25 Fujisawa Pharmaceutical Co Triazine derivatives
JPS59196874A (ja) * 1983-04-22 1984-11-08 Fujisawa Pharmaceut Co Ltd トリアジン誘導体

Also Published As

Publication number Publication date
KR930003852B1 (ko) 1993-05-14
EP0238357A3 (en) 1988-10-05
EP0238357B1 (en) 1991-05-29
US4898862A (en) 1990-02-06
KR870008862A (ko) 1987-10-21
DE3770299D1 (de) 1991-07-04
EP0238357A2 (en) 1987-09-23

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