ES2053401A1 - Compuestos de imidazol y procedimientos para su prepacion. - Google Patents

Compuestos de imidazol y procedimientos para su prepacion.

Info

Publication number
ES2053401A1
ES2053401A1 ES09300033A ES9300033A ES2053401A1 ES 2053401 A1 ES2053401 A1 ES 2053401A1 ES 09300033 A ES09300033 A ES 09300033A ES 9300033 A ES9300033 A ES 9300033A ES 2053401 A1 ES2053401 A1 ES 2053401A1
Authority
ES
Spain
Prior art keywords
procedures
preparation
imidazole compounds
reaction
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09300033A
Other languages
English (en)
Other versions
ES2053401B1 (es
Inventor
Timothy Francis Gallagher
Jerry Leroy Adams
John C Lee
John Richard White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Priority to ES09300033A priority Critical patent/ES2053401B1/es
Priority to FR9302441A priority patent/FR2700331B3/fr
Priority to PT101273A priority patent/PT101273A/pt
Publication of ES2053401A1 publication Critical patent/ES2053401A1/es
Application granted granted Critical
Publication of ES2053401B1 publication Critical patent/ES2053401B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPUESTOS DE IMIDAZOL Y PROCEDIMIENTO PARA SU PREPARACION, DE FORMULA GENERAL FORMULA EN DONDE RSI1 SC, RSI2 SC, RSI3 SC Y RSI4 SC REPRESENTAN DIVERSOS RADICALES ORGANICOS O INORGANICOS. SE PREPARAN CONDENSANDO UNA ALFA-DICETONA CON UN ALDEHIDO Y POSTERIOR CIERRE DE ANILLO, O POR REACCION DE OXIDACION DE UNA ALFA-HIDROXICETONA O POR REACCION DE ESTA CON UNA AMIDINA O CON UN IMINOETER O REACCION DE UNA AMIDA CON UN NITRILO Y UN HALURO DE ACILO. LOS COMPUESTOS SE UTILIZAN PARA EL TRATAMIENTO DE ENFERMEDADES MEDIADAS POR CITOQUINAS.
ES09300033A 1992-01-13 1993-01-12 Compuestos de imidazol y procedimientos para su prepacion. Expired - Fee Related ES2053401B1 (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES09300033A ES2053401B1 (es) 1992-01-13 1993-01-12 Compuestos de imidazol y procedimientos para su prepacion.
FR9302441A FR2700331B3 (fr) 1993-01-12 1993-03-03 Gel aqueux nutritif pour plantes contenant de la carboxyméthylcellulose de sodium.
PT101273A PT101273A (pt) 1993-01-12 1993-05-21 Geleia nutriente aquosa

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81955192A 1992-01-13 1992-01-13
ES09300033A ES2053401B1 (es) 1992-01-13 1993-01-12 Compuestos de imidazol y procedimientos para su prepacion.

Publications (2)

Publication Number Publication Date
ES2053401A1 true ES2053401A1 (es) 1994-07-16
ES2053401B1 ES2053401B1 (es) 1995-03-01

Family

ID=26154686

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09300033A Expired - Fee Related ES2053401B1 (es) 1992-01-13 1993-01-12 Compuestos de imidazol y procedimientos para su prepacion.

Country Status (1)

Country Link
ES (1) ES2053401B1 (es)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221546A1 (de) * 1971-05-10 1972-11-16 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3772441A (en) * 1970-11-16 1973-11-13 Pfizer Anti-inflammatory imidazoles
EP0011111A1 (en) * 1978-09-27 1980-05-28 Smithkline Beckman Corporation 5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo-(2,1-b)-thiazole, process for its preparation and medical composition
WO1993014081A1 (en) * 1992-01-13 1993-07-22 Smithkline Beecham Corporation Imidazole derivatives and their use as cytokine inhibitors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3772441A (en) * 1970-11-16 1973-11-13 Pfizer Anti-inflammatory imidazoles
DE2221546A1 (de) * 1971-05-10 1972-11-16 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
EP0011111A1 (en) * 1978-09-27 1980-05-28 Smithkline Beckman Corporation 5-(4-Pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo-(2,1-b)-thiazole, process for its preparation and medical composition
WO1993014081A1 (en) * 1992-01-13 1993-07-22 Smithkline Beecham Corporation Imidazole derivatives and their use as cytokine inhibitors

Also Published As

Publication number Publication date
ES2053401B1 (es) 1995-03-01

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Effective date: 20110223