ATE206110T1 - Zns-aktive semicarbazone und diese enthaltende pharmazeutische zubereitungen - Google Patents

Zns-aktive semicarbazone und diese enthaltende pharmazeutische zubereitungen

Info

Publication number
ATE206110T1
ATE206110T1 AT96917304T AT96917304T ATE206110T1 AT E206110 T1 ATE206110 T1 AT E206110T1 AT 96917304 T AT96917304 T AT 96917304T AT 96917304 T AT96917304 T AT 96917304T AT E206110 T1 ATE206110 T1 AT E206110T1
Authority
AT
Austria
Prior art keywords
semicarbazones
cns
active
pharmaceutical preparations
preparations containing
Prior art date
Application number
AT96917304T
Other languages
English (en)
Inventor
Jonathan Richard Dimmock
Ramanan Narayan Puthucode
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23887035&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE206110(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Application granted granted Critical
Publication of ATE206110T1 publication Critical patent/ATE206110T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
    • C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
    • C07C281/14—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96917304T 1995-06-07 1996-06-07 Zns-aktive semicarbazone und diese enthaltende pharmazeutische zubereitungen ATE206110T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/475,313 US5741818A (en) 1995-06-07 1995-06-07 Semicarbazones having CNS activity and pharmaceutical preparations containing same
PCT/CA1996/000380 WO1996040628A1 (en) 1995-06-07 1996-06-07 Semicarbazones having cns activity and pharmaceutical preparations containing same

Publications (1)

Publication Number Publication Date
ATE206110T1 true ATE206110T1 (de) 2001-10-15

Family

ID=23887035

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96917304T ATE206110T1 (de) 1995-06-07 1996-06-07 Zns-aktive semicarbazone und diese enthaltende pharmazeutische zubereitungen

Country Status (24)

Country Link
US (2) US5741818A (de)
EP (1) EP0836591B1 (de)
JP (1) JPH11506109A (de)
KR (1) KR19990022408A (de)
CN (1) CN1062263C (de)
AT (1) ATE206110T1 (de)
AU (1) AU715897B2 (de)
BR (1) BR9609408A (de)
CA (1) CA2223935A1 (de)
CZ (1) CZ387497A3 (de)
DE (1) DE69615558T2 (de)
DK (1) DK0836591T3 (de)
ES (1) ES2164889T3 (de)
FI (1) FI974447L (de)
GE (1) GEP20012414B (de)
HU (1) HUP9802637A3 (de)
IL (1) IL122350A0 (de)
NO (1) NO310655B1 (de)
NZ (1) NZ309707A (de)
PL (1) PL184048B1 (de)
PT (1) PT836591E (de)
RU (1) RU2174115C2 (de)
UA (1) UA62915C2 (de)
WO (1) WO1996040628A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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US5741818A (en) 1995-06-07 1998-04-21 University Of Saskatchewan Semicarbazones having CNS activity and pharmaceutical preparations containing same
WO1998047869A1 (en) 1997-04-22 1998-10-29 Cocensys, Inc. Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
EP1568690A1 (de) * 1997-04-22 2005-08-31 Euro-Celtique S.A. Durch carbozyklische und heterozyklische substituierte Semicarbazone und Thiosemicarbazone und ihre Anwendung als Natriumkanalblocker
ES2352739T3 (es) 1997-11-21 2011-02-22 Purdue Neuroscience Company 2-aminoacetamidas sustituidas y el uso de las mismas.
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
EP1058550A4 (de) * 1998-02-04 2002-12-18 Euro Celtique Sa Substituierte semicarbazide und deren verwendung
US6281211B1 (en) 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
ES2345921T3 (es) 1999-03-26 2010-10-06 Euro-Celtique S.A. Pirazoles, imidazoles, oxazoles, tiazoles y pirroles sustituidos con arilo y su uso.
WO2000061188A1 (en) * 1999-04-09 2000-10-19 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
JP2003518038A (ja) 1999-12-20 2003-06-03 ニコラス， ジェイ カークホフ， 流動床噴霧乾燥によるナノ粒子製造方法
US8771740B2 (en) 1999-12-20 2014-07-08 Nicholas J. Kerkhof Process for producing nanoparticles by spray drying
AR029489A1 (es) 2000-03-10 2003-07-02 Euro Celtique Sa Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento
CA2400778C (en) * 2000-03-24 2011-05-03 Purdue Pharma L.P. Aryl substituted pyrazoles, triazoles and tetrazoles, and the use thereof
GB0025208D0 (en) 2000-10-13 2000-11-29 Euro Celtique Sa Delayed release pharmaceutical formulations
EP1392219A4 (de) 2001-05-10 2007-01-24 Cytovia Inc Substituierte n'-(arylcarbonyl)-benzhydrazide, n'-(arylcarbonyl)-benzyliden-hydrazide und analoga als aktivatoren von caspasen und induktoren der apotosis und ihre anwendung
WO2002098420A1 (en) * 2001-06-01 2002-12-12 Cytovia, Inc. 4-substituted-1-(arylmethylidene)thiosemicarbazide, 4-substituted-1-(arylcarbonyl)thiosemicarbazide and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2003006426A1 (en) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Aromatic guanylhydrazones as effective compounds against neurodiseases
SI1423168T1 (sl) 2001-09-03 2006-06-30 Newron Pharm Spa Farmacevtski sestavek, ki vsebuje gabapentin ali njegov analog in alfa-aminoamid, in njegova analgetska uporaba
AR036873A1 (es) 2001-09-07 2004-10-13 Euro Celtique Sa Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
AR037233A1 (es) 2001-09-07 2004-11-03 Euro Celtique Sa Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento
WO2003096982A2 (en) * 2002-05-16 2003-11-27 Cytovia, Inc. Substituted 4h-chromenes, 2h-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2003097806A2 (en) * 2002-05-16 2003-11-27 Cytovia, Inc. Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof
EP1438956A1 (de) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind
US20080096965A1 (en) * 2004-09-10 2008-04-24 Newron Pharmaceuticals S.P.A. (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators
CA2963784A1 (en) 2007-06-08 2008-12-18 Mannkind Corporation Ire-1.alpha. inhibitors
EP2387481B1 (de) * 2008-12-10 2018-03-14 Boston Scientific Scimed, Inc. Verfahren zum verbinden von titanlegierung und stahllegierung und medizinisches bauteil mit einer solchen verbindung
CN104402771B (zh) * 2014-11-26 2016-09-28 玉林师范学院 对羟基苯甲醛缩氨基脲的合成及在防治植物病害中的应用
CN104974053B (zh) * 2015-06-24 2017-04-26 天津久日新材料股份有限公司 一种新的氨基酮类光引发剂及在uv‑led光固化体系的应用

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
BE667022A (de)
US3255241A (en) 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
NL129087C (de) 1961-01-19
BE622079A (de) 1961-09-11
US3251064A (en) 1962-11-13 1966-05-10 Everett M Schultz beta-aminoacylphenoxy-and beta-aminoacylphenylmercapto-derivatives of monocarboxylicacids
NL300456A (de) 1962-11-13
BE643709A (de) * 1963-02-12 1900-01-01
DE1288086B (de) * 1963-12-26 1969-01-30
US3392171A (en) * 1964-03-20 1968-07-09 Upjohn Co 4-morpholino-4'-hydroxy bicyclohexyls
US3304323A (en) * 1964-03-20 1967-02-14 Upjohn Co Oxygenated dicycloalkyl sulfones
US3303214A (en) * 1964-05-13 1967-02-07 Wallace & Tiernan Inc Nitrososemicarbazides
GB1164608A (en) * 1966-08-23 1969-09-17 May & Baker Ltd Semicarbazone and Thiosemicarbazone Quaternary Salts
US3712914A (en) * 1970-05-14 1973-01-23 Stauffer Chemical Co Arylidene semicarbizides
DE2420618C2 (de) * 1974-04-27 1982-09-16 C.H. Boehringer Sohn, 6507 Ingelheim Aminoalkylanilide, Verfahren zu ihrer Herstellung sowie pharmazeutische Zubereitungen, die diese Aminoalkylanilide enthalten
US4394514A (en) * 1981-04-30 1983-07-19 Smithkline Beckman Corporation Processes for preparing 4-substituted indoles
FI77458C (fi) * 1981-05-12 1989-03-10 Ciba Geigy Ag Nya mikrobicida arylfenyleterderivat, foerfarande foer deras framstaellning och deras anvaendning.
US5266585A (en) 1981-05-12 1993-11-30 Ciba-Geigy Corporation Arylphenyl ether derivatives, compositions containing these compounds and use thereof
US4454337A (en) * 1981-06-29 1984-06-12 Smithkline Beckman Corporation Semicarbazide intermediates for preparing 4-substituted indoles
US5665673A (en) 1988-12-29 1997-09-09 Anderson; Richard J. Potentiating herbicidal compositions
IL94466A (en) 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
WO1994006758A1 (en) * 1992-09-21 1994-03-31 University Of Saskatchewan Aryl semicarbazone anticonvulsants
CA2189573A1 (en) 1994-05-17 1995-11-23 Ronald E. Hackler N-(5-isothiazolyl)amide pesticides
US5741818A (en) 1995-06-07 1998-04-21 University Of Saskatchewan Semicarbazones having CNS activity and pharmaceutical preparations containing same
CZ132798A3 (cs) 1995-10-30 1999-02-17 Smithkline Beecham Corporation Inhibitory proteázy

Also Published As

Publication number Publication date
FI974447A7 (fi) 1997-12-05
US5741818A (en) 1998-04-21
NZ309707A (en) 1998-11-25
USRE38425E1 (en) 2004-02-10
ES2164889T3 (es) 2002-03-01
DE69615558T2 (de) 2002-07-11
CN1062263C (zh) 2001-02-21
PL184048B1 (pl) 2002-08-30
PL323666A1 (en) 1998-04-14
NO310655B1 (no) 2001-08-06
UA62915C2 (en) 2004-01-15
WO1996040628A1 (en) 1996-12-19
CA2223935A1 (en) 1996-12-19
BR9609408A (pt) 1999-07-27
AU715897B2 (en) 2000-02-10
KR19990022408A (ko) 1999-03-25
AU5993896A (en) 1996-12-30
PT836591E (pt) 2002-03-28
DK0836591T3 (da) 2001-11-26
CZ387497A3 (cs) 1998-07-15
HUP9802637A3 (en) 2000-09-28
EP0836591B1 (de) 2001-09-26
CN1190388A (zh) 1998-08-12
NO975663L (no) 1998-02-09
FI974447A0 (fi) 1997-12-05
FI974447L (fi) 1997-12-05
NO975663D0 (no) 1997-12-05
GEP20012414B (en) 2001-04-25
JPH11506109A (ja) 1999-06-02
EP0836591A1 (de) 1998-04-22
HUP9802637A2 (hu) 1999-02-01
DE69615558D1 (de) 2001-10-31
IL122350A0 (en) 1998-04-05
RU2174115C2 (ru) 2001-09-27

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Legal Events

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UEP Publication of translation of european patent specification
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