ES2053702T3 - Nuevas formulas de galenica de accion programada. - Google Patents

Nuevas formulas de galenica de accion programada.

Info

Publication number
ES2053702T3
ES2053702T3 ES88121777T ES88121777T ES2053702T3 ES 2053702 T3 ES2053702 T3 ES 2053702T3 ES 88121777 T ES88121777 T ES 88121777T ES 88121777 T ES88121777 T ES 88121777T ES 2053702 T3 ES2053702 T3 ES 2053702T3
Authority
ES
Spain
Prior art keywords
new
active ingredient
galenica
therapeutic
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88121777T
Other languages
English (en)
Inventor
Leone Gabriele Rotini
Egidio Marchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Wasserman SpA
Original Assignee
Alfa Wasserman SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wasserman SpA filed Critical Alfa Wasserman SpA
Application granted granted Critical
Publication of ES2053702T3 publication Critical patent/ES2053702T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

NUEVAS FORMULAS GALENICAS CON LIBERACION PROGRAMADA, A SER ADMINISTRADO POR VIA ORAL, CONTENIENDO COMO INGREDIENTE ACTIVO UNA DROGA SELECCIONADA DE DROGAS NO ESTEROIDES ANTIINFLAMATORIA, BRONQUIO DILATADOR, VASODILATADOR, CARDIOVASCULAR Y RELAJANTE DE MUSCULO. EN ESTAS NUEVAS FORMULAS, UNA PARTE DEL INGREDIENTE ACTIVO ES LIBERADO EN UN CORTO TIEMPO, TAL QUE LA DROGA PUEDE RAPIDAMENTE DESARROLLAR SU ACCION TERAPEUTICA QUE ALCANZA LOS NECESARIOS NIVELES HEMATICOS, MIENTRAS LA PARTE REMANENTE DEL CONSTITUYENTE ACTIVO ES LIBERADO EN UN INTERVALO MAS LARGO DE TIEMPO PARA PERMITIR LA COBERTURA TERAPEUTICA HASTA LA SUBSECUENTE ADMINISTRACION. DICHA COBERTURA TERAPEUTICA PUEDE IGUALAR LAS ULTIMAS 24 HORAS; ASI LAS NUEVAS FORMULAS GALENICAS OBJETO DEL PRESENTE INVENTO SON CONVENIENTES PARA UNA VEZ AL DIA LA ADMINISTRACION.
ES88121777T 1988-01-18 1988-12-28 Nuevas formulas de galenica de accion programada. Expired - Lifetime ES2053702T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819100A IT1215726B (it) 1988-01-18 1988-01-18 Formulazioni galeniche a cessione programmata.

Publications (1)

Publication Number Publication Date
ES2053702T3 true ES2053702T3 (es) 1994-08-01

Family

ID=11154525

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88121777T Expired - Lifetime ES2053702T3 (es) 1988-01-18 1988-12-28 Nuevas formulas de galenica de accion programada.

Country Status (16)

Country Link
US (1) US5043167A (es)
EP (1) EP0324981B1 (es)
JP (1) JPH01279823A (es)
KR (1) KR890011587A (es)
AT (1) ATE86480T1 (es)
AU (1) AU611517B2 (es)
DE (1) DE3879166T2 (es)
DK (1) DK18089A (es)
ES (1) ES2053702T3 (es)
FI (1) FI890238L (es)
GR (1) GR3007312T3 (es)
IT (1) IT1215726B (es)
NO (1) NO890194L (es)
NZ (1) NZ227631A (es)
PT (1) PT89467B (es)
ZA (1) ZA89100B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8824392D0 (en) * 1988-10-18 1988-11-23 Ciba Geigy Ag Dispersible formulation
US5256699A (en) * 1988-10-18 1993-10-26 Ciba-Geify Corporation Dispersible tablet formulation of diclofenac acid free base
US4948581A (en) * 1989-02-17 1990-08-14 Dojin Iyaku-Kako Co., Ltd. Long acting diclofenac sodium preparation
FR2649611A1 (fr) * 1989-07-13 1991-01-18 Philippe Perovitch Procede de preparation galenique d'une composition therapeutique notamment a base d'aspirine
EP0497977B1 (en) * 1989-10-26 1995-03-15 Nippon Shinyaku Company, Limited Gastric preparation
IE66933B1 (en) * 1990-01-15 1996-02-07 Elan Corp Plc Controlled absorption naproxen formulation for once-daily administration
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
US5683721A (en) * 1990-07-26 1997-11-04 Perovitch; Philippe Galenic preparation of therapeutic composition comprising aspirin
JP2829794B2 (ja) * 1991-02-08 1998-12-02 エスエス製薬 株式会社 徐放性経口投与型プラノプロフェン製剤
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
WO1993017673A1 (en) * 1992-03-03 1993-09-16 Top Gold Pty., Limited Sustained release analgesics
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
IT1258143B (it) * 1992-09-11 1996-02-20 Alfa Wassermann Spa Compresse a cessione programmata contenenti naproxen
IT1264020B (it) * 1993-01-28 1996-09-09 Recordati Chem Pharm Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
GB9403857D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives
FR2735369B1 (fr) * 1995-06-13 1997-07-11 Synthelabo Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside
US5914134A (en) * 1997-01-27 1999-06-22 Wockhardt Europe Limited Process for the pulsatile delivery of diltiazem HCL and product produced thereby
US6312724B1 (en) 1997-04-04 2001-11-06 Isa Odidi Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof
AU9062998A (en) * 1997-09-11 1999-03-29 Nycomed Danmark A/S Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (nsaids)
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
PT1218889E (pt) * 1999-09-28 2010-03-08 Panacea Biotec Ltd Composições de libertação controlada compreendendo nimesulida
KR100717549B1 (ko) * 1999-12-22 2007-05-11 파마시아 코포레이션 시클로옥시게나제-2 억제제의 이중-방출 조성물
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
US7056533B2 (en) 2000-08-15 2006-06-06 Surmodics, Inc. Medicament incorporation matrix
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
DE60312642T2 (de) * 2002-01-09 2007-11-29 Ucb Farchim S.A. Pharmazeutische zusammensetzung mit modifizierter freisetzung
EP1591109B1 (en) * 2004-04-30 2008-07-02 TopoTarget Germany AG Formulation comprising histone deacetylase inhibitor exhibiting biphasic release
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US8128460B2 (en) * 2006-09-14 2012-03-06 The Material Works, Ltd. Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
US20110144207A1 (en) * 2008-08-14 2011-06-16 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
WO2011036114A1 (en) * 2009-09-25 2011-03-31 Novartis Ag Oral pharmaceutical composition comprising diclofenac

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
US4012498A (en) * 1974-03-27 1977-03-15 Sandoz, Inc. Sustained release tablet formulations
JPS5661311A (en) * 1979-10-25 1981-05-26 Fujisawa Pharmaceut Co Ltd Thial amide or prolonged pharmaceutical preparation comprising its salt
JPS5846019A (ja) * 1981-09-14 1983-03-17 Kanebo Ltd 持続性ニフエジピン製剤
JPS6144811A (ja) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd 徐放性ジクロフエナクナトリウム製剤
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
JPS63162620A (ja) * 1986-12-25 1988-07-06 Teisan Seiyaku Kk 遅溶性顆粒及びそれを用いた持続性複合顆粒
JPS63267720A (ja) * 1987-04-24 1988-11-04 Morishita Seiyaku Kk エモルフアゾンの徐放性製剤
JPS6468317A (en) * 1987-09-08 1989-03-14 Dainippon Pharmaceutical Co Durative preparation

Also Published As

Publication number Publication date
AU611517B2 (en) 1991-06-13
PT89467B (pt) 1993-12-31
PT89467A (pt) 1990-02-08
KR890011587A (ko) 1989-08-21
FI890238A7 (fi) 1989-07-19
ATE86480T1 (de) 1993-03-15
EP0324981B1 (en) 1993-03-10
FI890238A0 (fi) 1989-01-17
GR3007312T3 (es) 1993-07-30
DE3879166T2 (de) 1993-08-19
ZA89100B (en) 1989-11-29
NZ227631A (en) 1990-12-21
DK18089A (da) 1989-07-19
EP0324981A1 (en) 1989-07-26
IT1215726B (it) 1990-02-22
NO890194L (no) 1989-07-19
IT8819100A0 (it) 1988-01-18
US5043167A (en) 1991-08-27
DK18089D0 (da) 1989-01-17
NO890194D0 (no) 1989-01-17
DE3879166D1 (de) 1993-04-15
AU2766689A (en) 1989-07-20
FI890238L (fi) 1989-07-19
JPH01279823A (ja) 1989-11-10

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