ES2053797T3 - Procedimiento microbiano para la obtencion de derivados de milbemicina. - Google Patents

Procedimiento microbiano para la obtencion de derivados de milbemicina.

Info

Publication number
ES2053797T3
ES2053797T3 ES88810049T ES88810049T ES2053797T3 ES 2053797 T3 ES2053797 T3 ES 2053797T3 ES 88810049 T ES88810049 T ES 88810049T ES 88810049 T ES88810049 T ES 88810049T ES 2053797 T3 ES2053797 T3 ES 2053797T3
Authority
ES
Spain
Prior art keywords
image
represent
formulae
milbemicine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88810049T
Other languages
English (en)
Spanish (es)
Inventor
Gerado Dr Ramos
Oreste Dr Ghisalba
Hans-Peter Dr Schar
Bruno Dr Frei
Peter Dr Maienfisch
Anthony Cornelius D O'sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2053797T3 publication Critical patent/ES2053797T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/525—Streptomyces diastatochromogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/685—Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES88810049T 1987-02-04 1988-01-29 Procedimiento microbiano para la obtencion de derivados de milbemicina. Expired - Lifetime ES2053797T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH39587 1987-02-04

Publications (1)

Publication Number Publication Date
ES2053797T3 true ES2053797T3 (es) 1994-08-01

Family

ID=4186037

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88810049T Expired - Lifetime ES2053797T3 (es) 1987-02-04 1988-01-29 Procedimiento microbiano para la obtencion de derivados de milbemicina.

Country Status (7)

Country Link
EP (1) EP0277916B1 (de)
JP (2) JP2719785B2 (de)
AT (1) ATE106081T1 (de)
DE (1) DE3889676D1 (de)
DK (1) DK54388A (de)
ES (1) ES2053797T3 (de)
IL (1) IL85292A0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
CA1339481C (en) * 1988-10-18 1997-09-30 Shieh-Shung Tom Chen Anthelmintic bioconversion products
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5225338A (en) * 1990-09-24 1993-07-06 Merck & Co., Inc. Microbial preparation of 13β-13-deoxy-22,23-dihydro avermectin-B1A/B1B aglycone
CN114940907B (zh) * 2022-01-05 2024-04-02 内蒙古工业大学 一种重金属污染土修复剂及其修复方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
US4696922A (en) * 1984-11-26 1987-09-29 Ciba-Geigy Corporation 5-azolylacetoxymilbemycins as ecto- and endoparasites

Also Published As

Publication number Publication date
DK54388D0 (da) 1988-02-03
JP2719785B2 (ja) 1998-02-25
IL85292A0 (en) 1988-07-31
EP0277916B1 (de) 1994-05-25
EP0277916A2 (de) 1988-08-10
JP2838400B2 (ja) 1998-12-16
DE3889676D1 (de) 1994-06-30
DK54388A (da) 1988-08-05
ATE106081T1 (de) 1994-06-15
JPS63216888A (ja) 1988-09-09
JPH1066593A (ja) 1998-03-10
EP0277916A3 (en) 1989-10-25

Similar Documents

Publication Publication Date Title
AU5670690A (en) Lysolecithin derivatives for treating autoimmune diseases
ES2053797T3 (es) Procedimiento microbiano para la obtencion de derivados de milbemicina.
NZ226222A (en) Preparation of n-alkylated alpha-aminodiacids and esters thereof, and use of those compounds in the synthesis of n-heterocyclic dipeptides
NO885112L (no) Oestrogent virksomt middel.
IE45008L (en) Allethrolone sulphonates.
ES2071873T3 (es) Procedimiento para la preparacion de compuestos de 1-oxa-3,8-diaza-4-oxo-espiro(4,5)decano.
ES8304971A1 (es) Un procedimiento para la preparacion de derivados de tiocarbapenem 3-sustituidos.
SE8303719D0 (sv) Novel eburnane oxime derivatives and process for preparing same
AU527523B2 (en) Hexahydro-1,4-oxazepines
ATE49971T1 (de) Imidazo(1,2-a>-pyrimidine und ihre salze mit saeuren, verfahren und zwischenprodukte zu ihrer herstellung, verwendung als arzneimittel und diese enthaltende zubereitungen.
IE791930L (en) Cyclohexadienes.
GB8721376D0 (en) Chemical compounds
HU905000D0 (en) Process for producing compounds suitable for treatment of gastric ulcer
ES2127845T3 (es) Procedimiento para la preparacion de 5-cloroimidazol-4-carbaldehidos sustituidos en posicion 2.
DE69204766D1 (de) Verfahren zur Herstellung von Bicyclo(3.2.0)hept-2-en-7-onen.
GR3005805T3 (de)
ATE33493T1 (de) Phenylethylaminopropiophenon-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ES2004215A6 (es) Procedimiento para preparar quinazolinas tetraciclicas
ES2055155T3 (es) Procedimiento para la obtencion de aciloxiacetidinonas opticamente activas.
ES2070925T3 (es) Procedimiento para la preparacion de 14beta-hidroxi-esteroides.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 277916

Country of ref document: ES