ES2058111T3 - Composicion de liberacion controlada de dihidrocodeina. - Google Patents

Composicion de liberacion controlada de dihidrocodeina.

Info

Publication number
ES2058111T3
ES2058111T3 ES87304363T ES87304363T ES2058111T3 ES 2058111 T3 ES2058111 T3 ES 2058111T3 ES 87304363 T ES87304363 T ES 87304363T ES 87304363 T ES87304363 T ES 87304363T ES 2058111 T3 ES2058111 T3 ES 2058111T3
Authority
ES
Spain
Prior art keywords
dihydrocodeine
released
hours
weight
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87304363T
Other languages
English (en)
Inventor
Robert Stronech Goldie
Sandra Therese Antoi Malkowska
Stewart Thomas Leslie
Ronald Brown Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26290900&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2058111(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868614153A external-priority patent/GB8614153D0/en
Priority claimed from GB868621206A external-priority patent/GB8621206D0/en
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of ES2058111T3 publication Critical patent/ES2058111T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Amplifiers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

UNA FORMA DE DOSIFICACION ORAL, DE LIBERACION CONTROLADA, SOLIDA, QUE COMPRENDE UNA CANTIDAD ANALGESICAMENTE EFICAZ DE DIHIDROCODEINA O UNA DE SUS SALES EN UNA MATRIZ DE LIBERACION CONTROLADA, EN LA QUE LA VELOCIDAD DE DISOLUCION IN VITRO DE LA FORMA DE DOSIFICACION, CUANDO SE MIDE SEGUN EL METODO DE PALETAS USP A 100 RPM EN 900 ML DE TAMPON ACUOSO (PH ENTRE 1,6 Y 7,2) A 37 (GRADOS) C, ESTA ENTRE 25 Y 60 % (EN PESO) DE DIHIDROCODEINA LIBERADA DESPUES DE 1 HORA, ENTRE 45 Y 80 % (EN PESO) DE DIHIDROCODEINA LIBERADA DESPUES DE 2 HORAS, ENTRE 60 Y 90 % (EN PESO) DE DIHIDROCODEINA LIBERADA DESPUES DE 3 HORAS, Y ENTRE 70 Y 100 % (EN PESO) DE DIHIDROCODEINA LIBERADA DESPUES DE 4 HORAS, SIENDO LA VELOCIDAD DE LIBERACION IN VITRO INDEPENDIENTE DEL PH ENTRE PH 1,6 Y 7,2, Y SELECCIONADA DE MODO QUE EL NIVEL DE PLASMA DEL PICO DE DIHIDROCODEINA OBTENIDA IN VIVO SE ENCUENTRE ENTRE 2 Y 4, DESPUES DE ADMINISTRADA LA FORMA DE DOSIFICACION.
ES87304363T 1986-06-10 1987-05-18 Composicion de liberacion controlada de dihidrocodeina. Expired - Lifetime ES2058111T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868614153A GB8614153D0 (en) 1986-06-10 1986-06-10 Dihydrocodeine composition
GB868621206A GB8621206D0 (en) 1986-09-02 1986-09-02 Dihydrocodeine composition

Publications (1)

Publication Number Publication Date
ES2058111T3 true ES2058111T3 (es) 1994-11-01

Family

ID=26290900

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87304363T Expired - Lifetime ES2058111T3 (es) 1986-06-10 1987-05-18 Composicion de liberacion controlada de dihidrocodeina.

Country Status (11)

Country Link
US (1) US4834984A (es)
EP (1) EP0249347B1 (es)
JP (1) JP2568202B2 (es)
AT (1) ATE107857T1 (es)
AU (1) AU600950B2 (es)
CA (1) CA1288350C (es)
DE (1) DE3750145T2 (es)
DK (1) DK175138B1 (es)
ES (1) ES2058111T3 (es)
IE (1) IE60069B1 (es)
SG (1) SG53293G (es)

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US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
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US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
IL109944A (en) † 1993-07-01 1998-12-06 Euro Celtique Sa Sustained release dosage unit forms containing morphine and a method of preparing these sustained release dosage unit forms
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
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Also Published As

Publication number Publication date
DK293087A (da) 1987-12-11
EP0249347A3 (en) 1988-03-23
IE871526L (en) 1987-12-10
EP0249347A2 (en) 1987-12-16
JP2568202B2 (ja) 1996-12-25
IE60069B1 (en) 1994-06-01
DK293087D0 (da) 1987-06-09
SG53293G (en) 1993-06-25
ATE107857T1 (de) 1994-07-15
EP0249347B1 (en) 1994-06-29
JPS62292720A (ja) 1987-12-19
DE3750145T2 (de) 1994-11-03
CA1288350C (en) 1991-09-03
DK175138B1 (da) 2004-06-14
AU600950B2 (en) 1990-08-30
US4834984A (en) 1989-05-30
DE3750145D1 (de) 1994-08-04
AU7407387A (en) 1987-12-17

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