ES2061724T3 - Derivados de sacarido. - Google Patents

Derivados de sacarido.

Info

Publication number
ES2061724T3
ES2061724T3 ES88810646T ES88810646T ES2061724T3 ES 2061724 T3 ES2061724 T3 ES 2061724T3 ES 88810646 T ES88810646 T ES 88810646T ES 88810646 T ES88810646 T ES 88810646T ES 2061724 T3 ES2061724 T3 ES 2061724T3
Authority
ES
Spain
Prior art keywords
sacarido
derivatives
forculates
acil
immuno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88810646T
Other languages
English (en)
Inventor
Ingolf Macher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of ES2061724T3 publication Critical patent/ES2061724T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06Fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Ceramic Products (AREA)
  • Glass Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LOS SACARIDOS DE LA FORMULA(I) DONDE R1, R2 Y R3 INDEPENDIENTEMENTE SE SUSTITUYEN OPCIONALMENTE CON ACILO, SON NUEVOS. TIENE INTERES FARMACOLOGICO, ESPECIALMENTE PROPIEDADES ANTITUMOR, ANTIINFLAMATORIAS E INMUNOESTIMULANTES. SE PUEDEN OBTENER POR DESPROTECCION DEL CORRESPONDIENTE COMPUESTO EN FORMA PROTEGIDA.
ES88810646T 1987-09-23 1988-09-21 Derivados de sacarido. Expired - Lifetime ES2061724T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873731953 DE3731953A1 (de) 1987-09-23 1987-09-23 Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2061724T3 true ES2061724T3 (es) 1994-12-16

Family

ID=6336635

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88810646T Expired - Lifetime ES2061724T3 (es) 1987-09-23 1988-09-21 Derivados de sacarido.

Country Status (18)

Country Link
EP (1) EP0309411B1 (es)
JP (1) JP2744912B2 (es)
KR (1) KR970005346B1 (es)
AT (1) ATE102213T1 (es)
AU (1) AU614772B2 (es)
CA (1) CA1335892C (es)
DE (2) DE3731953A1 (es)
DK (1) DK170170B1 (es)
ES (1) ES2061724T3 (es)
FI (1) FI89494C (es)
HU (1) HU201559B (es)
IE (1) IE63517B1 (es)
IL (1) IL87799A0 (es)
MY (1) MY103552A (es)
NZ (1) NZ226274A (es)
PL (1) PL157779B1 (es)
PT (1) PT88568B (es)
ZA (1) ZA887161B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429522B1 (en) * 1988-08-19 1996-06-26 The Australian National University Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
AU627500B2 (en) * 1988-08-19 1992-08-27 Australian National University, The Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
US5597573A (en) * 1989-05-04 1997-01-28 Igen, Inc. Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities
DD295854A5 (de) * 1989-12-11 1991-11-14 ��@���������@�������k�� Lipid-a-austauschstoffe mit immunoaktivierender und antitumorwirkung
US5593969A (en) * 1991-09-03 1997-01-14 Igen Incorporated Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors
BR0104461A (pt) * 2000-02-10 2002-08-06 Mitsui Chemicals Inc Processo seletivo para produzir um anÈmero a partir de um derivado de sacarìdeo 1-fosforilado e processo para produzir um nucleosìdeo
CA2317305A1 (en) * 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
FR2862062B1 (fr) * 2003-11-06 2005-12-23 Oreal Lipide a et composition topique, notamment cosmetique, le comprenant
EP3707147B1 (en) * 2017-11-07 2025-03-05 Università Degli Studi Di Milano - Bicocca New synthetic agonists of tlr4 receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004526A1 (en) * 1983-05-06 1984-11-22 Wisconsin Alumni Res Found Monosaccharide compounds having immunostimulating activity
EP0180608B1 (en) 1984-04-21 1990-07-25 Sandoz Ag 2,3-diamino-2,3-didesoxyhexose derivatives, processes for their preparation and their use
WO1986005687A1 (en) * 1985-04-03 1986-10-09 Wisconsin Alumni Research Foundation Method of preventing diseases caused by gram-negative endotoxin in mammals
HU199494B (en) 1985-06-28 1990-02-28 Sandoz Ag Process for producing new saccharides and pharmaceutical compositions comprising same
US4746742A (en) * 1985-11-28 1988-05-24 Toho Yakuhin Kogyo Kabushiki Kaisha Analogs of nonreducing monosaccharide moiety of lipid A

Also Published As

Publication number Publication date
EP0309411B1 (en) 1994-03-02
KR890005138A (ko) 1989-05-13
KR970005346B1 (ko) 1997-04-15
EP0309411A3 (en) 1991-07-24
IE882859L (en) 1989-03-23
HU201559B (en) 1990-11-28
FI884345A0 (fi) 1988-09-21
PL157779B1 (pl) 1992-07-31
AU614772B2 (en) 1991-09-12
DK170170B1 (da) 1995-06-06
EP0309411A2 (en) 1989-03-29
IE63517B1 (en) 1995-05-03
FI884345L (fi) 1989-03-24
AU2278588A (en) 1989-04-20
MY103552A (en) 1993-07-31
ZA887161B (en) 1990-05-30
HUT50193A (en) 1989-12-28
PL274862A1 (en) 1989-06-12
DK525588A (da) 1989-03-24
DE3888066D1 (de) 1994-04-07
DE3731953A1 (de) 1989-04-06
DK525588D0 (da) 1988-09-21
FI89494B (fi) 1993-06-30
CA1335892C (en) 1995-06-13
PT88568A (pt) 1988-10-01
NZ226274A (en) 1991-03-26
FI89494C (fi) 1993-10-11
IL87799A0 (en) 1989-03-31
DE3888066T2 (de) 1994-08-04
PT88568B (pt) 1992-11-30
ATE102213T1 (de) 1994-03-15
JP2744912B2 (ja) 1998-04-28
JPH01121295A (ja) 1989-05-12

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