ES2061724T3 - Derivados de sacarido. - Google Patents
Derivados de sacarido.Info
- Publication number
- ES2061724T3 ES2061724T3 ES88810646T ES88810646T ES2061724T3 ES 2061724 T3 ES2061724 T3 ES 2061724T3 ES 88810646 T ES88810646 T ES 88810646T ES 88810646 T ES88810646 T ES 88810646T ES 2061724 T3 ES2061724 T3 ES 2061724T3
- Authority
- ES
- Spain
- Prior art keywords
- sacarido
- derivatives
- forculates
- acil
- immuno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Ceramic Products (AREA)
- Glass Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LOS SACARIDOS DE LA FORMULA(I) DONDE R1, R2 Y R3 INDEPENDIENTEMENTE SE SUSTITUYEN OPCIONALMENTE CON ACILO, SON NUEVOS. TIENE INTERES FARMACOLOGICO, ESPECIALMENTE PROPIEDADES ANTITUMOR, ANTIINFLAMATORIAS E INMUNOESTIMULANTES. SE PUEDEN OBTENER POR DESPROTECCION DEL CORRESPONDIENTE COMPUESTO EN FORMA PROTEGIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873731953 DE3731953A1 (de) | 1987-09-23 | 1987-09-23 | Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2061724T3 true ES2061724T3 (es) | 1994-12-16 |
Family
ID=6336635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88810646T Expired - Lifetime ES2061724T3 (es) | 1987-09-23 | 1988-09-21 | Derivados de sacarido. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0309411B1 (es) |
| JP (1) | JP2744912B2 (es) |
| KR (1) | KR970005346B1 (es) |
| AT (1) | ATE102213T1 (es) |
| AU (1) | AU614772B2 (es) |
| CA (1) | CA1335892C (es) |
| DE (2) | DE3731953A1 (es) |
| DK (1) | DK170170B1 (es) |
| ES (1) | ES2061724T3 (es) |
| FI (1) | FI89494C (es) |
| HU (1) | HU201559B (es) |
| IE (1) | IE63517B1 (es) |
| IL (1) | IL87799A0 (es) |
| MY (1) | MY103552A (es) |
| NZ (1) | NZ226274A (es) |
| PL (1) | PL157779B1 (es) |
| PT (1) | PT88568B (es) |
| ZA (1) | ZA887161B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0429522B1 (en) * | 1988-08-19 | 1996-06-26 | The Australian National University | Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs |
| AU627500B2 (en) * | 1988-08-19 | 1992-08-27 | Australian National University, The | Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs |
| US5597573A (en) * | 1989-05-04 | 1997-01-28 | Igen, Inc. | Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities |
| DD295854A5 (de) * | 1989-12-11 | 1991-11-14 | ��@���������@�������k�� | Lipid-a-austauschstoffe mit immunoaktivierender und antitumorwirkung |
| US5593969A (en) * | 1991-09-03 | 1997-01-14 | Igen Incorporated | Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors |
| BR0104461A (pt) * | 2000-02-10 | 2002-08-06 | Mitsui Chemicals Inc | Processo seletivo para produzir um anÈmero a partir de um derivado de sacarìdeo 1-fosforilado e processo para produzir um nucleosìdeo |
| CA2317305A1 (en) * | 2000-08-29 | 2002-02-28 | Tassos P. Anastassiades | Method of enhancing chondrocyte cell growth and glycosaminoglycan production |
| FR2862062B1 (fr) * | 2003-11-06 | 2005-12-23 | Oreal | Lipide a et composition topique, notamment cosmetique, le comprenant |
| EP3707147B1 (en) * | 2017-11-07 | 2025-03-05 | Università Degli Studi Di Milano - Bicocca | New synthetic agonists of tlr4 receptor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984004526A1 (en) * | 1983-05-06 | 1984-11-22 | Wisconsin Alumni Res Found | Monosaccharide compounds having immunostimulating activity |
| EP0180608B1 (en) | 1984-04-21 | 1990-07-25 | Sandoz Ag | 2,3-diamino-2,3-didesoxyhexose derivatives, processes for their preparation and their use |
| WO1986005687A1 (en) * | 1985-04-03 | 1986-10-09 | Wisconsin Alumni Research Foundation | Method of preventing diseases caused by gram-negative endotoxin in mammals |
| HU199494B (en) | 1985-06-28 | 1990-02-28 | Sandoz Ag | Process for producing new saccharides and pharmaceutical compositions comprising same |
| US4746742A (en) * | 1985-11-28 | 1988-05-24 | Toho Yakuhin Kogyo Kabushiki Kaisha | Analogs of nonreducing monosaccharide moiety of lipid A |
-
1987
- 1987-09-23 DE DE19873731953 patent/DE3731953A1/de not_active Withdrawn
-
1988
- 1988-09-19 IL IL87799A patent/IL87799A0/xx active Protection Beyond IP Right Term
- 1988-09-20 HU HU884921A patent/HU201559B/hu unknown
- 1988-09-21 MY MYPI88001053A patent/MY103552A/en unknown
- 1988-09-21 AT AT88810646T patent/ATE102213T1/de not_active IP Right Cessation
- 1988-09-21 EP EP88810646A patent/EP0309411B1/en not_active Expired - Lifetime
- 1988-09-21 IE IE285988A patent/IE63517B1/en not_active IP Right Cessation
- 1988-09-21 FI FI884345A patent/FI89494C/fi not_active IP Right Cessation
- 1988-09-21 PT PT88568A patent/PT88568B/pt not_active IP Right Cessation
- 1988-09-21 DK DK525588A patent/DK170170B1/da active IP Right Grant
- 1988-09-21 NZ NZ226274A patent/NZ226274A/en unknown
- 1988-09-21 ES ES88810646T patent/ES2061724T3/es not_active Expired - Lifetime
- 1988-09-21 DE DE3888066T patent/DE3888066T2/de not_active Expired - Lifetime
- 1988-09-22 JP JP63239548A patent/JP2744912B2/ja not_active Expired - Lifetime
- 1988-09-22 CA CA000578482A patent/CA1335892C/en not_active Expired - Lifetime
- 1988-09-22 KR KR1019880012262A patent/KR970005346B1/ko not_active Expired - Fee Related
- 1988-09-23 ZA ZA887161A patent/ZA887161B/xx unknown
- 1988-09-23 AU AU22785/88A patent/AU614772B2/en not_active Expired
- 1988-09-23 PL PL1988274862A patent/PL157779B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0309411B1 (en) | 1994-03-02 |
| KR890005138A (ko) | 1989-05-13 |
| KR970005346B1 (ko) | 1997-04-15 |
| EP0309411A3 (en) | 1991-07-24 |
| IE882859L (en) | 1989-03-23 |
| HU201559B (en) | 1990-11-28 |
| FI884345A0 (fi) | 1988-09-21 |
| PL157779B1 (pl) | 1992-07-31 |
| AU614772B2 (en) | 1991-09-12 |
| DK170170B1 (da) | 1995-06-06 |
| EP0309411A2 (en) | 1989-03-29 |
| IE63517B1 (en) | 1995-05-03 |
| FI884345L (fi) | 1989-03-24 |
| AU2278588A (en) | 1989-04-20 |
| MY103552A (en) | 1993-07-31 |
| ZA887161B (en) | 1990-05-30 |
| HUT50193A (en) | 1989-12-28 |
| PL274862A1 (en) | 1989-06-12 |
| DK525588A (da) | 1989-03-24 |
| DE3888066D1 (de) | 1994-04-07 |
| DE3731953A1 (de) | 1989-04-06 |
| DK525588D0 (da) | 1988-09-21 |
| FI89494B (fi) | 1993-06-30 |
| CA1335892C (en) | 1995-06-13 |
| PT88568A (pt) | 1988-10-01 |
| NZ226274A (en) | 1991-03-26 |
| FI89494C (fi) | 1993-10-11 |
| IL87799A0 (en) | 1989-03-31 |
| DE3888066T2 (de) | 1994-08-04 |
| PT88568B (pt) | 1992-11-30 |
| ATE102213T1 (de) | 1994-03-15 |
| JP2744912B2 (ja) | 1998-04-28 |
| JPH01121295A (ja) | 1989-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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