DK525588A - Saccharidderivater - Google Patents

Saccharidderivater

Info

Publication number: DK525588A
Authority: DK; Denmark
Prior art keywords: saccharide; immunostimulant; antiinflammatory; saccharides; deprotection
Prior art date: 1987-09-23

Application number

DK525588A

Other languages

English (en)

Other versions

DK525588D0 (da

DK170170B1 (da

Inventor

Ingolf Macher

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-23

Filing date

1988-09-21

Publication date

1989-03-24

1988-09-21 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-09-21 Publication of DK525588D0 publication Critical patent/DK525588D0/da

1989-03-24 Publication of DK525588A publication Critical patent/DK525588A/da

1995-06-06 Application granted granted Critical

1995-06-06 Publication of DK170170B1 publication Critical patent/DK170170B1/da

Links

150000001720 carbohydrates Chemical class 0.000 title abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000010511 deprotection reaction Methods 0.000 abstract 1
229960001438 immunostimulant agent Drugs 0.000 abstract 1
239000003022 immunostimulating agent Substances 0.000 abstract 1
230000003308 immunostimulating effect Effects 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Virology (AREA)
Toxicology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Ceramic Products (AREA)
Glass Compositions (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK525588A 1987-09-23 1988-09-21 Alfa-D-Glucopyranosederivater, fremgangsmåde til fremstilling og farmaceutisk komposition med indhold deraf DK170170B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19873731953 DE3731953A1 (de)	1987-09-23	1987-09-23	Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
DE3731953		1987-09-23

Publications (3)

Publication Number	Publication Date
DK525588D0 DK525588D0 (da)	1988-09-21
DK525588A true DK525588A (da)	1989-03-24
DK170170B1 DK170170B1 (da)	1995-06-06

Family

ID=6336635

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK525588A DK170170B1 (da)	1987-09-23	1988-09-21	Alfa-D-Glucopyranosederivater, fremgangsmåde til fremstilling og farmaceutisk komposition med indhold deraf

Country Status (18)

Country	Link
EP (1)	EP0309411B1 (da)
JP (1)	JP2744912B2 (da)
KR (1)	KR970005346B1 (da)
AT (1)	ATE102213T1 (da)
AU (1)	AU614772B2 (da)
CA (1)	CA1335892C (da)
DE (2)	DE3731953A1 (da)
DK (1)	DK170170B1 (da)
ES (1)	ES2061724T3 (da)
FI (1)	FI89494C (da)
HU (1)	HU201559B (da)
IE (1)	IE63517B1 (da)
IL (1)	IL87799A0 (da)
MY (1)	MY103552A (da)
NZ (1)	NZ226274A (da)
PL (1)	PL157779B1 (da)
PT (1)	PT88568B (da)
ZA (1)	ZA887161B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU627500B2 (en) *	1988-08-19	1992-08-27	Australian National University, The	Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
WO1990001938A1 (en) *	1988-08-19	1990-03-08	The Australian National University	Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
US5597573A (en) *	1989-05-04	1997-01-28	Igen, Inc.	Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities
RU1836378C (ru) *	1989-12-11	1993-08-23	Санкио Компани Лимитед	Способ получени аналогов липида А
US5593969A (en) *	1991-09-03	1997-01-14	Igen Incorporated	Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors
BR0104461A (pt) *	2000-02-10	2002-08-06	Mitsui Chemicals Inc	Processo seletivo para produzir um anÈmero a partir de um derivado de sacarìdeo 1-fosforilado e processo para produzir um nucleosìdeo
CA2317305A1 (en) *	2000-08-29	2002-02-28	Tassos P. Anastassiades	Method of enhancing chondrocyte cell growth and glycosaminoglycan production
FR2862062B1 (fr) *	2003-11-06	2005-12-23	Oreal	Lipide a et composition topique, notamment cosmetique, le comprenant
DK3707147T3 (da) *	2017-11-07	2025-06-10	Univ Degli Studi Di Milano Bicocca	Nye syntetiske agonister af tlr4-receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60501259A (ja) *	1983-05-06	1985-08-08	ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン	免疫刺激活性をもつ単糖類化合物
DE3578866D1 (de)	1984-04-21	1990-08-30	Sandoz Ag	2,3-diamino-2,3-didesoxyhexose-derivate, verfahren zu ihrer herstellung und ihre verwendung.
WO1986005687A1 (en) *	1985-04-03	1986-10-09	Wisconsin Alumni Research Foundation	Method of preventing diseases caused by gram-negative endotoxin in mammals
HU199494B (en)	1985-06-28	1990-02-28	Sandoz Ag	Process for producing new saccharides and pharmaceutical compositions comprising same
US4746742A (en) *	1985-11-28	1988-05-24	Toho Yakuhin Kogyo Kabushiki Kaisha	Analogs of nonreducing monosaccharide moiety of lipid A

1987
- 1987-09-23 DE DE19873731953 patent/DE3731953A1/de not_active Withdrawn
1988
- 1988-09-19 IL IL87799A patent/IL87799A0/xx active Protection Beyond IP Right Term
- 1988-09-20 HU HU884921A patent/HU201559B/hu unknown
- 1988-09-21 EP EP88810646A patent/EP0309411B1/en not_active Expired - Lifetime
- 1988-09-21 NZ NZ226274A patent/NZ226274A/en unknown
- 1988-09-21 FI FI884345A patent/FI89494C/fi not_active IP Right Cessation
- 1988-09-21 ES ES88810646T patent/ES2061724T3/es not_active Expired - Lifetime
- 1988-09-21 AT AT88810646T patent/ATE102213T1/de not_active IP Right Cessation
- 1988-09-21 MY MYPI88001053A patent/MY103552A/en unknown
- 1988-09-21 DK DK525588A patent/DK170170B1/da active IP Right Grant
- 1988-09-21 PT PT88568A patent/PT88568B/pt not_active IP Right Cessation
- 1988-09-21 DE DE3888066T patent/DE3888066T2/de not_active Expired - Lifetime
- 1988-09-21 IE IE285988A patent/IE63517B1/en not_active IP Right Cessation
- 1988-09-22 CA CA000578482A patent/CA1335892C/en not_active Expired - Lifetime
- 1988-09-22 JP JP63239548A patent/JP2744912B2/ja not_active Expired - Lifetime
- 1988-09-22 KR KR1019880012262A patent/KR970005346B1/ko not_active Expired - Fee Related
- 1988-09-23 ZA ZA887161A patent/ZA887161B/xx unknown
- 1988-09-23 PL PL1988274862A patent/PL157779B1/pl unknown
- 1988-09-23 AU AU22785/88A patent/AU614772B2/en not_active Expired

Also Published As

Publication number	Publication date
AU614772B2 (en)	1991-09-12
ATE102213T1 (de)	1994-03-15
IE882859L (en)	1989-03-23
ES2061724T3 (es)	1994-12-16
ZA887161B (en)	1990-05-30
PL157779B1 (pl)	1992-07-31
PT88568A (pt)	1988-10-01
EP0309411A3 (en)	1991-07-24
JPH01121295A (ja)	1989-05-12
EP0309411A2 (en)	1989-03-29
DE3888066D1 (de)	1994-04-07
DE3888066T2 (de)	1994-08-04
NZ226274A (en)	1991-03-26
FI89494B (fi)	1993-06-30
PL274862A1 (en)	1989-06-12
DK525588D0 (da)	1988-09-21
FI884345L (fi)	1989-03-24
KR970005346B1 (ko)	1997-04-15
KR890005138A (ko)	1989-05-13
IL87799A0 (en)	1989-03-31
DK170170B1 (da)	1995-06-06
FI884345A0 (fi)	1988-09-21
FI89494C (fi)	1993-10-11
IE63517B1 (en)	1995-05-03
EP0309411B1 (en)	1994-03-02
HUT50193A (en)	1989-12-28
DE3731953A1 (de)	1989-04-06
JP2744912B2 (ja)	1998-04-28
MY103552A (en)	1993-07-31
PT88568B (pt)	1992-11-30
CA1335892C (en)	1995-06-13
HU201559B (en)	1990-11-28
AU2278588A (en)	1989-04-20

Legal Events

Date	Code	Title	Description
1995-06-06	B1	Patent granted (law 1993)

Publication	Publication Date	Title
ES2077138T3 (es)	1995-11-16	Derivados de aminocumarano, su produccion y su uso.
RU95110682A (ru)	1996-12-27	Способ получения производных таксана, исходные и промежуточные продукты для его получения
FI102069B1 (fi)	1998-10-15	Menetelmä terapeuttisesti käyttökelpoisten indolijohdannaisten valmistamiseksi
ATE54917T1 (de)	1990-08-15	Physostigminderivate mit acetylcholinesteraseinhibitoreigenschaften, und das entsprechende herstellungsverfahren.
NO890567D0 (no)	1989-02-09	Anthracyklin-derivater.
FI951046L (fi)	1995-03-07	Parannettuja entsyymejä 2-keto-L-gulonihapon tuotantoon
ATE42303T1 (de)	1989-05-15	Herstellung von nukleosiden.
DK525588D0 (da)	1988-09-21	Saccharidderivater
NO920614D0 (no)	1992-02-17	Forbindelse med antitumorvirkning og fremstilling derav
FI881892A7 (fi)	1988-10-25	Menetelmä uusien, terapeuttisesti käyttökelpoisten 1,2,5,6-tetrahydropyridiinijohdannaisten valmistamiseksi
BE869395A (fr)	1978-11-16	Procede de production de nouveaux derives d'anthracycline
FI892946A7 (fi)	1989-12-16	Menetelmä uusien terapeuttisesti käyttökelpoisten 2,3,4,5-tetrahydro-1H-3-bentsoatsepiinijohdannaisten valmistamiseksi
FI903232A0 (fi)	1990-06-27	Muramyldipeptidderivator.
DE69029781D1 (de)	1997-03-06	Anthracyclinglycosid-Derivate und Verfahren zu ihrer Herstellung
ES2054327T3 (es)	1994-08-01	Sintesis de derivados de manojirimicina.
EP0297594A3 (en)	1990-07-25	Novel 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
AU1254188A (en)	1989-09-07	Disaccharide derivatives
DK165452C (da)	1993-04-13	7-0-(2,6-dideoxy-2-fluor-alfa-l-talopyranosyl)-adriamycinon-14-0-acylderivater, deres fremstilling og anvendelse
FI913699A0 (fi)	1991-08-02	Menetelmä farmaseuttisesti käyttökelpoisten 4'-epi-4'-aminoantrasykliinien valmistamiseksi sekä menetelmässä käytettävät välituotteet
DE68900638D1 (de)	1992-02-13	4-substituierte anthracyclinone und anthracyclinonglycoside und ihre herstellung.
FI890678A0 (fi)	1989-02-13	Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi
FI910159A7 (fi)	1991-01-11	Menetelmä uusien, terapeuttisesti käyttökelpoisten 9a-hydroksi-3-okso- 4,24(25)-stigmastadieeni-26-happojohdannaisten valmistamiseksi
FI893434A7 (fi)	1990-01-16	Menetelmä uusien terapeuttisesti käyttökelpoisten sykloalkyylitiatsolijohdannaisten valmistamiseksi
ATE87926T1 (de)	1993-04-15	Ethylierte avermectine.
JPS6461494A (en)	1989-03-08	Production of 5'-0-acyl-5-fluorouridine derivative