ES2063173T3 - Empleo de polietileniminas alquiladas como medicamentos absorbedores de acido biliar, asi como preparados farmaceuticos. - Google Patents

Empleo de polietileniminas alquiladas como medicamentos absorbedores de acido biliar, asi como preparados farmaceuticos.

Info

Publication number
ES2063173T3
ES2063173T3 ES90100887T ES90100887T ES2063173T3 ES 2063173 T3 ES2063173 T3 ES 2063173T3 ES 90100887 T ES90100887 T ES 90100887T ES 90100887 T ES90100887 T ES 90100887T ES 2063173 T3 ES2063173 T3 ES 2063173T3
Authority
ES
Spain
Prior art keywords
rented
polyethylenimines
well
pharmaceutical preparations
acid absorbing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90100887T
Other languages
English (en)
Inventor
Walter Prof Dr Heitz
Thomas Fischer
Bela Dr Kerekjarto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2063173T3 publication Critical patent/ES2063173T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • C08G73/0213—Preparatory process
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/742—Organic compounds containing oxygen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00—Preservation of foods or foodstuffs, in general
    • A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
    • A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
    • A23B2/729—Organic compounds; Microorganisms; Enzymes
    • A23B2/767—Organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

EL INVENTO DESCRIBE UNA NUEVA POLIETILENOIMINA ALQUILADA RETICULADA O NO RETICULADA QUE PUEDE EMPLEARSE COMO HIPOLIPIDAMINA POR SU ACTIVIDAD FORMADOR DE ACIDO BILIAR; TRATA DE UN PROCEDIMIENTO PARA LA PRODUCCION DE POLIETILENOIMINA Y REFIERE SU APLICACION COMO PREPARADO FARMACEUTICO.
ES90100887T 1989-01-20 1990-01-17 Empleo de polietileniminas alquiladas como medicamentos absorbedores de acido biliar, asi como preparados farmaceuticos. Expired - Lifetime ES2063173T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3901527A DE3901527A1 (de) 1989-01-20 1989-01-20 Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ES2063173T3 true ES2063173T3 (es) 1995-01-01

Family

ID=6372414

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90100887T Expired - Lifetime ES2063173T3 (es) 1989-01-20 1990-01-17 Empleo de polietileniminas alquiladas como medicamentos absorbedores de acido biliar, asi como preparados farmaceuticos.

Country Status (15)

Country Link
EP (1) EP0379161B1 (es)
JP (1) JPH02232229A (es)
AT (1) ATE111931T1 (es)
AU (1) AU624215B2 (es)
CA (1) CA2008114A1 (es)
DE (2) DE3901527A1 (es)
DK (1) DK0379161T3 (es)
ES (1) ES2063173T3 (es)
FI (1) FI900297A7 (es)
IE (1) IE65618B1 (es)
IL (1) IL93098A0 (es)
NO (1) NO900279L (es)
NZ (1) NZ232149A (es)
PT (1) PT92880B (es)
ZA (1) ZA90394B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0534316A1 (de) * 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Verwendung von alkylierten Polyethyleniminderivaten zur Anreicherung von Gallensäuren
EP0534304A1 (de) * 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Cycloalkylierte Polyethyleniminderivate und ihre Verwendung als Hypolipidämika
ATE183924T1 (de) * 1992-01-14 1999-09-15 Hisamitsu Pharmaceutical Co Cholesterinspiegelsenkendes mittel
ATE130193T1 (de) * 1992-03-28 1995-12-15 Hoechst Ag Arzneimittel aus polyhydroxymethylenderivaten, verfahren zu deren herstellung und verwendung.
ATE159262T1 (de) * 1992-07-22 1997-11-15 Hoechst Ag Hydrophile zentren aufweisende polyvinylamin- derivate, verfahren zu ihrer herstellung sowie die verwendung der verbindungen als arzneimittel, wirkstoffträger und nahrungsmittelhilfsstoff
EP0580079B1 (de) * 1992-07-22 1996-12-11 Hoechst Aktiengesellschaft Vernetzte, stickstoffhaltige Vinylcopolymere, Verfahren zu ihrer Herstellung sowie die Verwendung dieser Verbindungen
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US5994391A (en) * 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6107494A (en) * 1994-09-13 2000-08-22 G.D. Searle And Company Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US20030069601A1 (en) 1998-12-15 2003-04-10 Closys Corporation Clotting cascade initiating apparatus and methods of use
AU3103800A (en) 1998-12-23 2000-07-31 G.D. Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acidderivatives for cardiovascular indications
BR9916486A (pt) 1998-12-23 2002-02-05 Searle Llc Combinações de inibidores do transporte de ácidos biliares no ìleo e inibidores da proteìna de transferência do ester colesteril para indicações cardiovasculares
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
US6458850B1 (en) 1998-12-23 2002-10-01 G.D. Searle, Llc Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
AU2157500A (en) 1998-12-23 2000-07-31 G.D. Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
EA004877B1 (ru) 1998-12-23 2004-08-26 Джи.Ди.Сирл Ллс Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний
DK1140189T3 (da) 1998-12-23 2003-09-15 Searle Llc Kombinationer af ileal galdesyre-transportinhibitorer og fibrinsyrederivater til cardiovaskulære indikationer
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
EP1286984A2 (en) 2000-03-10 2003-03-05 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
DE10065710A1 (de) * 2000-12-29 2002-07-04 Bayer Ag Arzneimittel enthaltend ein Polyamin als Wirksubstanz
BR0213501A (pt) 2001-11-02 2004-08-24 Searle Llc Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato
MXPA04006255A (es) 2002-01-17 2004-09-27 Pharmacia Corp Compuestos novedosos de alquil/aril hidroxi o ceto tiepina como inhibidores del transporte del acido biliar codependiente del sodio apical y la captacion de taurocolato.
GB0221942D0 (en) * 2002-09-20 2002-10-30 Univ Strathclyde Drug delivery
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
CN103027896B (zh) 2005-09-15 2016-01-20 基酶有限公司 胺聚合物的小袋制剂
US10231721B2 (en) 2010-06-24 2019-03-19 St. Croix Surgical Systems, Llc Failsafe percutaneous wound barrier
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
CN110907543A (zh) * 2019-09-29 2020-03-24 重庆健能医药开发有限公司 一种铝碳酸镁咀嚼片胆汁酸吸附的实验方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3251778A (en) * 1960-08-04 1966-05-17 Petrolite Corp Process of preventing scale
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent

Also Published As

Publication number Publication date
CA2008114A1 (en) 1990-07-20
FI900297A7 (fi) 1990-07-21
ATE111931T1 (de) 1994-10-15
EP0379161A2 (de) 1990-07-25
AU4861890A (en) 1990-07-26
EP0379161A3 (de) 1991-07-31
DE59007178D1 (de) 1994-10-27
PT92880A (pt) 1990-07-31
AU624215B2 (en) 1992-06-04
NO900279L (no) 1990-07-23
NZ232149A (en) 1991-12-23
IE65618B1 (en) 1995-11-01
IE900214L (en) 1990-07-20
EP0379161B1 (de) 1994-09-21
IL93098A0 (en) 1990-11-05
FI900297A0 (fi) 1990-01-18
JPH02232229A (ja) 1990-09-14
DK0379161T3 (da) 1995-01-16
ZA90394B (en) 1991-04-24
NO900279D0 (no) 1990-01-19
DE3901527A1 (de) 1990-07-26
PT92880B (pt) 1995-12-29

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