ES2064112T3 - Composicion farmaceutica para suspension rapida en agua. - Google Patents

Composicion farmaceutica para suspension rapida en agua.

Info

Publication number
ES2064112T3
ES2064112T3 ES91912620T ES91912620T ES2064112T3 ES 2064112 T3 ES2064112 T3 ES 2064112T3 ES 91912620 T ES91912620 T ES 91912620T ES 91912620 T ES91912620 T ES 91912620T ES 2064112 T3 ES2064112 T3 ES 2064112T3
Authority
ES
Spain
Prior art keywords
water
suspension
pharmaceutical composition
medicinal product
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912620T
Other languages
English (en)
Inventor
Marco Zema
Luigi Giovanni Mapelli
Marco Giuseppe Raffael Marconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Eurand International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand International SpA filed Critical Eurand International SpA
Application granted granted Critical
Publication of ES2064112T3 publication Critical patent/ES2064112T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B2275/00—Other engines, components or details, not provided for in other groups of this subclass
    • F02B2275/14—Direct injection into combustion chamber

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION PRESENTA UNA COMPOSICION FARMACEUTICA SOLIDA PARA AÑADIRLA AL AGUA PARA PRODUCIR UNA SUSPENSION DE UN MEDICAMENTO QUE COMPRENDE (A) UN MEDICAMENTO QUE ES SUSTANCIALMENTE INDISOLUBLE EN AGUA O MICROENCAPSULADO; (B) UN AGENTE ESPESADOR O DE SUSPENSION; (C) UN ACIDO FARMACEUTICAMENTE ACEPTABLE; (D) UN CARBONATO O BICARBONATO FARMACEUTICAMENTE ACEPTABLES; QUE SE CARACTERIZA PORQUE LA RELACION DE PESO DE C+D:B ES DE 1:1,5 A 1:15 Y LA CANTIDAD DE C+D ES SUFICIENTE PARA OBTENER UNA HIDRATACION RAPIDA DEL AGENTE ESPESADOR O DE SUSPENSION (B) CUANDO LA COMPOSICION SE MEZCLA CON AGUA DE MODO QUE SE OBTIENE UNA SUSPENSION HOMOGENEA DEL MEDICAMENTO EN 30 SEGUNDOS. TAMBIEN SE DESCRIBE UN METODO PARA LA PREPARACION DE LA COMPOSICION.
ES91912620T 1990-07-11 1991-07-04 Composicion farmaceutica para suspension rapida en agua. Expired - Lifetime ES2064112T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02090890A IT1246350B (it) 1990-07-11 1990-07-11 Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili

Publications (1)

Publication Number Publication Date
ES2064112T3 true ES2064112T3 (es) 1995-01-16

Family

ID=11173904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912620T Expired - Lifetime ES2064112T3 (es) 1990-07-11 1991-07-04 Composicion farmaceutica para suspension rapida en agua.

Country Status (16)

Country Link
US (1) US5306506A (es)
EP (1) EP0491910B1 (es)
JP (1) JP2552785B2 (es)
KR (1) KR100209175B1 (es)
AT (1) ATE113832T1 (es)
AU (1) AU640253B2 (es)
CA (1) CA2046679C (es)
DE (1) DE69105106T2 (es)
DK (1) DK0491910T3 (es)
ES (1) ES2064112T3 (es)
IE (1) IE66048B1 (es)
IT (1) IT1246350B (es)
NZ (1) NZ238901A (es)
PT (1) PT98272B (es)
WO (1) WO1992000731A1 (es)
ZA (1) ZA915284B (es)

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DK0679088T3 (da) * 1992-09-29 2002-10-28 Inhale Therapeutic Syst Pulmonal levering af aktive fragmenter af parathyreoideaea hormon
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ES2133454T3 (es) * 1993-09-07 1999-09-16 Gergely Gerhard Mezcla efervescente con sales alcalinas o lisinatos de principios activos acidos, insolubles o dificilmente solubles.
FR2712809B1 (fr) * 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
DE69535897D1 (de) * 1994-03-07 2009-01-22 Nektar Therapeutics Verfahren und Zusammensetzung für die pulmonale Darreichung von Insulin
ATE208133T1 (de) * 1994-04-11 2001-11-15 Dsm Nv Stabile natamycin-suspensionen
AU696387B2 (en) * 1994-05-18 1998-09-10 Inhale Therapeutic Systems, Inc. Methods and compositions for the dry powder formulation of interferons
WO1995033490A1 (en) * 1994-06-02 1995-12-14 Enzon, Inc. Method of solubilizing substantially water insoluble materials
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
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US5958455A (en) * 1996-02-09 1999-09-28 Quadrant Holdings Cambridge Ltd Oral solid dosage forms, methods of making same and compositions thereof
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GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
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US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
NZ333474A (en) 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
IL136899A0 (en) * 2000-06-20 2001-06-14 Caretec Ltd Microcapsules containing arginine and the different uses thereof
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US6884436B2 (en) 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
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US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
TWI327474B (en) * 2001-04-06 2010-07-21 Neochemir Inc Kit for preparation of carbon dioxide agent for external use.
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
MXPA04002446A (es) 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
ITMI20022358A1 (it) * 2002-11-07 2004-05-08 Bsd Bioscience Dev Snc Composizioni farmaceutiche effervescenti per la realizzazione di sospensioni non convenzionali.
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US20050095320A1 (en) * 2003-10-29 2005-05-05 Richard Botteri [An Isotonic Sports Drink for Female Athletes Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Nutrition During Execise and Competition]
US20050100636A1 (en) * 2003-11-10 2005-05-12 Megan Botteri [A Low-Calorie Sports Drink For Physically Active Women That is Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Replacing Electrolytes Lost During Periods of Physical Activity]
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
PT2079445E (pt) * 2007-02-20 2016-02-29 Allergan Pharmaceuticals Internat Ltd Composições de enzimas digestivas estáveis
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US7782646B2 (en) * 2008-06-30 2010-08-24 International Business Machines Corporation High density content addressable memory using phase change devices
EA029101B1 (ru) 2010-10-01 2018-02-28 Апталис Фарма Лимитид Составы с низкой дозой панкрелипазы и кишечнорастворимым покрытием
CA2843556A1 (en) 2011-08-08 2013-02-14 Aptalis Pharma Ltd. Method for dissolution testing of solid compositions containing digestive enzymes
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JP5993336B2 (ja) * 2013-04-26 2016-09-14 株式会社メディオン・リサーチ・ラボラトリーズ 二酸化炭素経皮・経粘膜吸収用組成物
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Also Published As

Publication number Publication date
JP2552785B2 (ja) 1996-11-13
AU8183391A (en) 1992-02-04
WO1992000731A1 (en) 1992-01-23
ATE113832T1 (de) 1994-11-15
CA2046679C (en) 2001-11-20
KR920702215A (ko) 1992-09-03
EP0491910A1 (en) 1992-07-01
IT1246350B (it) 1994-11-17
JPH05501421A (ja) 1993-03-18
IE66048B1 (en) 1995-12-13
PT98272A (pt) 1992-05-29
IT9020908A1 (it) 1992-01-11
KR100209175B1 (ko) 1999-07-15
DE69105106D1 (de) 1994-12-15
PT98272B (pt) 1999-01-29
IE912382A1 (en) 1992-01-15
DE69105106T2 (de) 1995-04-27
ZA915284B (en) 1993-03-31
CA2046679A1 (en) 1992-01-12
AU640253B2 (en) 1993-08-19
IT9020908A0 (it) 1990-07-11
DK0491910T3 (da) 1995-01-09
EP0491910B1 (en) 1994-11-09
NZ238901A (en) 1992-08-26
US5306506A (en) 1994-04-26

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