ES2064748T3 - Composiciones antiviricas conteniendo derivados del sulfoquinovosil glicerol y analogos del mismo y su uso. - Google Patents

Composiciones antiviricas conteniendo derivados del sulfoquinovosil glicerol y analogos del mismo y su uso.

Info

Publication number
ES2064748T3
ES2064748T3 ES90911686T ES90911686T ES2064748T3 ES 2064748 T3 ES2064748 T3 ES 2064748T3 ES 90911686 T ES90911686 T ES 90911686T ES 90911686 T ES90911686 T ES 90911686T ES 2064748 T3 ES2064748 T3 ES 2064748T3
Authority
ES
Spain
Prior art keywords
hiv
sulfoquinovosil
antiviric
analogs
glycerol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90911686T
Other languages
English (en)
Inventor
Michael R Boyd
John H Ii Cardellina
Kenneth M Snader
Kirk R Gustafon
Gregory M L Patterson
James B Mcmahon
Owen S Weislow
Robert H Shoemaker
Kenneth D Paull
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Health and Human Services
Original Assignee
United States Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Health and Human Services filed Critical United States Department of Health and Human Services
Application granted granted Critical
Publication of ES2064748T3 publication Critical patent/ES2064748T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSICIONES ANTIVIRALES UTILES PARA LA INHIBICION DE LOS EFECTOS CITOPATICOS DEL VIRUS DE INMUNODEFICIENCIA HUMANA (HIV), QUE ESTA IMPLICADO COMO AGENTE CAUSADOR DEL (SIDA) SINDROME DE INMUNODEFICIENCIA ADQUIRIDA), INCLUYEN UNA NUEVA CLASE DE COMPUESTOS INHIBIDORES -HIV, LOS GLICOLIPIDOS CONTENIENDO EL ACIDO SULFONICO. LOS COMPUESTOS PUROS FUERON ACTIVOS CONTRA EL HIV EN LIMFOBLASTOIDES CEM HUMANOS CULTIVADOS, MT-2, LVD-7 Y LINEAS CELULARES C3-44 COMO SE INDICA EN EL ENSAYO TETRAZOILO, ASI COMO POR LA PROTEINA VIRAL CORRELATIVA P24 Y ENSAYOS DE FORMACION SINCITIA.
ES90911686T 1989-08-15 1990-08-03 Composiciones antiviricas conteniendo derivados del sulfoquinovosil glicerol y analogos del mismo y su uso. Expired - Lifetime ES2064748T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39378089A 1989-08-15 1989-08-15

Publications (1)

Publication Number Publication Date
ES2064748T3 true ES2064748T3 (es) 1995-02-01

Family

ID=23556218

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90911686T Expired - Lifetime ES2064748T3 (es) 1989-08-15 1990-08-03 Composiciones antiviricas conteniendo derivados del sulfoquinovosil glicerol y analogos del mismo y su uso.

Country Status (9)

Country Link
EP (1) EP0486536B1 (es)
JP (1) JPH0747540B2 (es)
AT (1) ATE113210T1 (es)
AU (1) AU635057B2 (es)
CA (1) CA2064772A1 (es)
DE (1) DE69013688T2 (es)
DK (1) DK0486536T3 (es)
ES (1) ES2064748T3 (es)
WO (1) WO1991002521A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774094B1 (fr) * 1998-01-26 2001-04-13 Ifremer Procede de purification de sulfoquinovosyldiacylglycerol par chromatographie de partage centrifuge
JP3851461B2 (ja) 1998-09-04 2006-11-29 東洋水産株式会社 ピラノシドおよびその製造方法
DE60003794T2 (de) 1999-02-26 2004-06-17 Toyo Suisan Kaisha, Ltd. Sulforhamnosylacylglycerin-derivate und ihre verwendung als medikamente
EA003094B1 (ru) 1999-02-26 2002-12-26 Тойо Суйсан Кайся, Лтд. Лекарственное средство, содержащее производное сульфопиранозилацилглицерина
CA2362903C (en) 1999-02-26 2006-06-13 Toyo Suisan Kaisha, Ltd. Novel sulfofucosylacylglycerol derivatives and use thereof as medicaments
US6518410B2 (en) 1999-02-26 2003-02-11 Toyo Suisan Kaisha, Ltd. Sulfoquinovosylacylglycerol derivative, and use thereof as medicaments
AU2001269486B2 (en) 2001-07-09 2005-02-17 Toyo Suisan Kaisha, Ltd. Novel immunosuppressants
FR2840318B1 (fr) * 2002-05-29 2004-12-03 Quoc Kiet Pham Nouveaux sulfolipides antiretroviraux extraits de spirulines, leur procede d'obtention, les compositions les contenant et leur utilisation comme inhibiteurs de la transcriptase inverse des virus vih
FR2867475B1 (fr) * 2004-06-10 2006-09-22 Quoc Kiet Pham Nouveaux sulfolipides antiretroviraux extraits de spirulines, leur procede d'obtention, les compositions les contenant et leur utilisation comme inhibiteurs de la transcriptase inverse des virus vih
BRPI0809936A2 (pt) 2007-07-20 2014-10-07 Toyo Suisan Kaisha Composto sulfonado de açúcar e uso do mesmo como medicamento

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0338092A1 (en) * 1987-10-30 1989-10-25 Chugai Seiyaku Kabushiki Kaisha Anti-hiv agent

Also Published As

Publication number Publication date
JPH05501105A (ja) 1993-03-04
DK0486536T3 (da) 1995-04-10
DE69013688T2 (de) 1995-05-18
DE69013688D1 (de) 1994-12-01
AU635057B2 (en) 1993-03-11
EP0486536A1 (en) 1992-05-27
AU6067990A (en) 1991-04-03
EP0486536A4 (en) 1992-09-16
CA2064772A1 (en) 1991-02-16
JPH0747540B2 (ja) 1995-05-24
WO1991002521A1 (en) 1991-03-07
EP0486536B1 (en) 1994-10-26
ATE113210T1 (de) 1994-11-15

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