ES2065499T3 - Alcohol sacarido cristalino que contiene compuesto farmaceutico particulado uniformemente disperso. - Google Patents

Alcohol sacarido cristalino que contiene compuesto farmaceutico particulado uniformemente disperso.

Info

Publication number
ES2065499T3
ES2065499T3 ES90312752T ES90312752T ES2065499T3 ES 2065499 T3 ES2065499 T3 ES 2065499T3 ES 90312752 T ES90312752 T ES 90312752T ES 90312752 T ES90312752 T ES 90312752T ES 2065499 T3 ES2065499 T3 ES 2065499T3
Authority
ES
Spain
Prior art keywords
crystalline
uniformly dispersed
pharmaceutical compound
saccharized
alcohol containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90312752T
Other languages
English (en)
Inventor
James Wix Duross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeneca Inc
Original Assignee
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23751666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2065499(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ICI Americas Inc filed Critical ICI Americas Inc
Application granted granted Critical
Publication of ES2065499T3 publication Critical patent/ES2065499T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCUBRE, UNA COMPOSICION FARMACEUTICA, QUE COMPRENDE UN ALCOHOL DE AZUCAR CRISTALINO DERIVADO DE AL MENOS UNA MONO O POLISACARIDA, TENIENDO UNIFORMEMENTE DISPERSAS EN SU INTERIOR PARTICULAS MATRICES CRISTALINAS DE AL MENOS UN COMPUESTO FARMACEUTICO ACTIVO. TAMBIEN SE DESCUBRE UN METODO PARA PRODUCIR DICHO COMPUESTO FARMACEUTICO UNIFORMEMENTE DISPERSO POR LA CRISTALIZACION CONTROLADA DE ALCOHOL DE AZUCAR DERRITIDO, TENIENDO DISPERSO DICHO MATERIAL FARMACEUTICAMENTE ACTIVO.
ES90312752T 1989-11-22 1990-11-22 Alcohol sacarido cristalino que contiene compuesto farmaceutico particulado uniformemente disperso. Expired - Lifetime ES2065499T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/441,131 US5075291A (en) 1989-11-22 1989-11-22 Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound

Publications (1)

Publication Number Publication Date
ES2065499T3 true ES2065499T3 (es) 1995-02-16

Family

ID=23751666

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90312752T Expired - Lifetime ES2065499T3 (es) 1989-11-22 1990-11-22 Alcohol sacarido cristalino que contiene compuesto farmaceutico particulado uniformemente disperso.

Country Status (14)

Country Link
US (1) US5075291A (es)
EP (1) EP0435450B1 (es)
JP (1) JP3307925B2 (es)
AT (1) ATE112676T1 (es)
AU (1) AU638074B2 (es)
CA (1) CA2030670C (es)
DE (1) DE69013314T2 (es)
ES (1) ES2065499T3 (es)
FI (1) FI95657C (es)
IE (1) IE904219A1 (es)
NO (1) NO905075L (es)
PT (1) PT95964A (es)
TW (1) TW217386B (es)
ZA (1) ZA909313B (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5158789A (en) * 1991-08-09 1992-10-27 Ici Americas Inc. Melt cocrystallized sorbitol/xylitol compositions
US5139795A (en) * 1991-08-09 1992-08-18 Ici Americas Inc. Melt crystallized xylitol
JPH069382A (ja) * 1992-04-17 1994-01-18 Takeda Chem Ind Ltd 安定化された固型製剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
US5405623A (en) * 1993-09-22 1995-04-11 Wm. Wrigley Jr. Company Chewing gum compositions and methods for manufacturing same
US6004589A (en) * 1993-09-24 1999-12-21 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of filler feed inlet locations
US6086925A (en) * 1993-09-24 2000-07-11 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of lubricating agents feed inlets
US5543160A (en) * 1994-09-13 1996-08-06 Wm. Wrigley Jr. Company Total chewing gum manufacture using high efficiency continuous mixing
US5397580A (en) * 1993-10-22 1995-03-14 Wm. Wrigley Jr. Company Continuous gum base manufacture using sequential mixers
US5773053A (en) * 1993-09-24 1998-06-30 Wm. Wrigley Jr. Company Chewing gum base manufacturing process using plurality of softening agents inlets
US5419919A (en) * 1993-10-22 1995-05-30 Wm. Wrigley Jr. Company Continuous gum base manufacture using paddle mixing
US5549757A (en) * 1994-06-10 1996-08-27 Ingredient Technology Corporation Process for recrystallizing sugar and product thereof
US6586006B2 (en) * 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
PL319143A1 (en) * 1994-09-13 1997-07-21 Wrigley W M Jun Co Continuous method of making chewing gum from the chewing gum base concentrate
JP2927556B2 (ja) * 1994-09-13 1999-07-28 ダブリューエム リグリー ジュニア カンパニー ガム基剤の製造方法
WO1996008232A1 (en) * 1994-09-15 1996-03-21 The Procter & Gamble Company Oral compositions
US5976581A (en) * 1995-09-12 1999-11-02 Wm. Wrigley Jr. Company Continuous chewing gum manufacturing process using rework gum
US5827549A (en) * 1996-02-21 1998-10-27 Wm. Wrigley, Jr. Company Process control system for automated continuous production of chewing gum
US6017565A (en) * 1996-02-21 2000-01-25 Wm. Wrigley Jr. Company Method for automated continuous production of chewing gum
DE19617487A1 (de) † 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
AU6519198A (en) 1997-03-31 1998-10-22 Kanebo Limited Melaninization inhibitor, skin-care preparation, and bath agent
US5840334A (en) * 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
US6123980A (en) * 1997-12-01 2000-09-26 Imperial Sugar Company Preparing granulated sugar blends and products
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US5948388A (en) * 1998-06-12 1999-09-07 Soft Gel Technologies, Inc. Chewable softgel oral hygiene product
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US20020098264A1 (en) * 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
AT407111B (de) * 1998-12-22 2000-12-27 Gergely Dr & Co Zucker- und/oder zuckeralkoholhältiges matrixmaterial und verfahren zu seiner herstellung
EP1189599A2 (en) * 1999-06-11 2002-03-27 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
JP4588818B2 (ja) * 1999-09-16 2010-12-01 日本化学機械製造株式会社 錠剤用賦形剤及び錠剤
US6793934B1 (en) 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
US6602912B2 (en) * 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US20070092583A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Cold remedy composition comprising zinc salts
US20070092552A1 (en) * 2003-04-30 2007-04-26 Tim Clarot Chewable lozenge cold remedy composition and method for making same
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
AT500101A1 (de) * 2004-02-04 2005-10-15 Tritthart Thomas Verkapselungsprozess
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
KR101482922B1 (ko) * 2004-08-12 2015-01-15 레킷트 벵키저 헬스케어(유케이)리미티드 용융 압출에 의해 제조된, ｎｓａｉｄ와 당 알콜을 포함하는 과립
US20090142401A1 (en) * 2005-06-07 2009-06-04 Leah Elizabeth Appel Multiparticulates comprising low-solubility drugs and carriers that result in rapid drug release
EP3263117A1 (en) 2005-11-28 2018-01-03 Imaginot Pty Ltd. Oral therapeutic compound delivery system
EP1832281A1 (en) * 2006-03-10 2007-09-12 Abbott GmbH & Co. KG Process for producing a solid dispersion of an active ingredient
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
WO2009052391A1 (en) * 2007-10-19 2009-04-23 Purdue Research Foundation Solid formulations of crystalline compounds
GB0813709D0 (en) * 2008-07-26 2008-09-03 Univ Dundee Method and product
US8828441B2 (en) 2009-12-22 2014-09-09 Firmenich Sa Active ingredient delivery system
JP5330320B2 (ja) * 2010-06-09 2013-10-30 日本化学機械製造株式会社 錠剤用賦形剤及び錠剤
DE102010033527A1 (de) 2010-08-05 2012-02-09 Acino Pharma Ag Quetiapin-Tabletten
DE102011115690A1 (de) 2011-10-11 2013-04-11 Acino Pharma Ag Quetiapin enthaltende Formulierungen
US20150080567A1 (en) * 2013-09-04 2015-03-19 Nalas Engineering Services Inc. Method to Produce and Scale-Up Cocrystals and Salts Via Resonant Acoustic Mixing
US9375033B2 (en) 2014-02-14 2016-06-28 R.J. Reynolds Tobacco Company Tobacco-containing gel composition
DE102014104676A1 (de) * 2014-04-02 2015-10-08 Heraeus Medical Gmbh Fosfomycin-Zubereitung, ein Verfahren zur Herstellung der Zubereitung und ein die Zubereitung enthaltendes Polymethylmethacrylat-Knochenzementpulver
CN112999181B (zh) * 2019-12-19 2023-11-14 鲁南制药集团股份有限公司 一种富马酸沃诺拉赞片剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200039A (en) * 1962-05-28 1965-08-10 Pfizer & Co C Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu
US3341415A (en) * 1964-02-12 1967-09-12 Warner Lambert Pharmaceutical Pharmaceutical tablet excipients of solid particles of a binary solid solution of mannitol with a sugar
US4252794A (en) * 1979-12-20 1981-02-24 Ici Americas Inc. Gamma-sorbitol polymorph
US4870059A (en) * 1985-11-27 1989-09-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Dehydration of hydrous matter with anhydrous maltose
US5017400A (en) * 1988-06-10 1991-05-21 Suomen Xyrofin Oy Non-cariogenic sweetener
US5023092A (en) * 1988-06-16 1991-06-11 Ici Americas Inc. Mannitol having gamma sorbitol polymorph
JPH075624B2 (ja) * 1989-01-31 1995-01-25 東和化成工業株式会社 ラクチトール三水和物結晶及びそれを含有する含蜜結晶並びにそれらの製造方法

Also Published As

Publication number Publication date
US5075291A (en) 1991-12-24
EP0435450A3 (en) 1991-09-04
NO905075L (no) 1991-05-23
EP0435450B1 (en) 1994-10-12
ZA909313B (en) 1991-10-30
JP3307925B2 (ja) 2002-07-29
PT95964A (pt) 1991-10-15
EP0435450A2 (en) 1991-07-03
JPH03209336A (ja) 1991-09-12
FI905781L (fi) 1991-05-23
CA2030670C (en) 2000-08-08
CA2030670A1 (en) 1991-05-23
AU6676990A (en) 1991-05-30
AU638074B2 (en) 1993-06-17
FI95657C (fi) 1996-03-11
IE904219A1 (en) 1991-05-22
DE69013314D1 (de) 1994-11-17
DE69013314T2 (de) 1995-02-16
FI905781A0 (fi) 1990-11-22
TW217386B (es) 1993-12-11
NO905075D0 (no) 1990-11-22
FI95657B (fi) 1995-11-30
ATE112676T1 (de) 1994-10-15

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