ES2065935T3 - Anticuerpos monoclonales de raton para hiv-i p24 y su uso en ensayos de diagnostico. - Google Patents

Anticuerpos monoclonales de raton para hiv-i p24 y su uso en ensayos de diagnostico.

Info

Publication number
ES2065935T3
ES2065935T3 ES89108001T ES89108001T ES2065935T3 ES 2065935 T3 ES2065935 T3 ES 2065935T3 ES 89108001 T ES89108001 T ES 89108001T ES 89108001 T ES89108001 T ES 89108001T ES 2065935 T3 ES2065935 T3 ES 2065935T3
Authority
ES
Spain
Prior art keywords
hiv
monoclonal antibody
antibodies
monoclonal antibodies
epitope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108001T
Other languages
English (en)
Inventor
Smriti U Mehta
Jeffrey C Hunt
Sushil G Devare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2065935T3 publication Critical patent/ES2065935T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1143—Gag-pol proteins, e.g. p17or p24
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/974—Aids related test
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

EL INVENTO SUMINISTRA ANTICUERPOS MONOCLONALES QUE DEMUESTRAN REACTIVIDAD ESPECIFICA CON HIV - 1 - P24. UN ANTICUERPO MONOCLONAL DESIGNADO (31, 42, 19) RECONOCE UN EPITOPO UNICO EN HIV - 1 - P24 QUE NO ES INMUNOGENICO EN LOS SERES HUMANOS. (31, 42, 19) TAMBIEN REACCIONA CON UN ANTIGENICAMENTE EPITOPO REACTIVO DE CRUECE SOBRE HIV - 2 P24. OTRO ANTICUERPO MONOCLONAL DESIGNADO 31, 90, 25 RECONOCE UN EPITOPO DENTRO DE UNA REGION ALTAMENTE INMUNOGENICA DE HIV - 1P24. EL PRESENTE INVENTO TAMBIEN SUMINISTRA LINEAS DE CELULAS CAPACES DE PRODUCIR ESTOS ANTICUERPOS MONOCLONALES. EL INVENTO TAMBIEN INCLUYE UN INMUNOENSAYO DE ENZIMA ALTAMENTE SENSITIVO PARA LA DETECCION DE HIV - 1 P24 EN FLUIDOS BIOLOGICOS, USANDO UNA MEZCLA DE ANTICUERPO MONOCLONAL. EL INVENTO ADEMAS SUMINISTRA METODOS PARA EL USO DE ESTOS ANTICUERPOS MONOCLONALES PARA LA DETECCION DE ANTICUERPOS HIV - 1 P24 Y ANTIGENO HIV - 2 P24 EN MUESTRAS BIOLOGICAS.
ES89108001T 1988-06-10 1989-05-03 Anticuerpos monoclonales de raton para hiv-i p24 y su uso en ensayos de diagnostico. Expired - Lifetime ES2065935T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/204,798 US5173399A (en) 1988-06-10 1988-06-10 Mouse monoclonal antibodies to hiv-1p24 and their use in diagnostic tests

Publications (1)

Publication Number Publication Date
ES2065935T3 true ES2065935T3 (es) 1995-03-01

Family

ID=22759480

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108001T Expired - Lifetime ES2065935T3 (es) 1988-06-10 1989-05-03 Anticuerpos monoclonales de raton para hiv-i p24 y su uso en ensayos de diagnostico.

Country Status (6)

Country Link
US (1) US5173399A (es)
EP (1) EP0345461B1 (es)
JP (1) JP3102643B2 (es)
CA (1) CA1340919C (es)
DE (1) DE68918497T2 (es)
ES (1) ES2065935T3 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983529A (en) * 1988-06-10 1991-01-08 Abbott Laboratories Immunoassay for HIV-I antigens using F(AB')2 fragments as probe
ZA903492B (en) * 1989-05-15 1991-02-27 Akzo Nv T-lymphotropic retrovirus monoclonal antibodies
EP0519866A1 (en) * 1991-06-18 1992-12-23 Ciba-Geigy Ag Novel anti-HIV antibodies
US6319665B1 (en) 1994-06-07 2001-11-20 Inverness Medical Technology, Inc. Home test kit and method with telephone verification of results
WO1996007102A1 (en) * 1994-09-01 1996-03-07 Wisconsin Alumni Research Foundation Therapeutic remodeling in aids
FR2777285B1 (fr) * 1998-04-10 2000-05-19 Bio Merieux Ligand peptidique presentant une affinite specifique vis-a-vis de la proteine p24 du retrovirus hiv-1
US6027731A (en) * 1998-11-17 2000-02-22 Wisconsin Alumni Research Foundation Pertussis toxin induced lymphocytosis
US6682940B2 (en) * 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6828157B1 (en) * 1999-05-04 2004-12-07 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
JP3536731B2 (ja) * 1999-07-28 2004-06-14 富士レビオ株式会社 ＨＩＶ−１ｐ２４抗原の免疫測定方法及び試薬
US6818392B2 (en) 2000-12-06 2004-11-16 Abbott Laboratories Monoclonal antibodies to human immunodeficiency virus and uses thereof
WO2006126286A1 (ja) * 2005-05-27 2006-11-30 Masami Moriyama Ｈｉｖ－１を認識する抗体を産生するハイブリドーマ
WO2006126287A1 (ja) * 2005-05-27 2006-11-30 Masami Moriyama Ｈｉｖ－１を検出する方法およびそれに使用するキット
WO2008059553A1 (en) * 2006-11-13 2008-05-22 Masami Moriyama Method for detecting hiv-1 without being affected by anti-mouse protein antibody existing in human and kit to be used for the same
JP2008170700A (ja) * 2007-01-11 2008-07-24 Yamaha Corp 鍵盤式打楽器
WO2009084369A1 (ja) 2007-12-28 2009-07-09 Sysmex Corporation Ｈｉｖ－１抗原の検出用試薬及び検出方法
JP5794917B2 (ja) * 2008-09-12 2015-10-14 アイシス・イノベーション・リミテッドＩｓｉｓ Ｉｎｎｏｖａｔｉｏｎｌｉｍｉｔｅｄ Ｐｄ−１特異抗体およびその使用
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
FR2994482B1 (fr) * 2012-08-13 2014-08-22 Repropharm Composition, procede et trousse de detection du pic preovulatoire de lh
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
US9632087B2 (en) * 2013-09-10 2017-04-25 MockV Solutions Methods for evaluating viral clearance from a biopharmaceutical solution employing mock viral particles
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
JP7810694B2 (ja) * 2020-07-13 2026-02-03 グリフォルス ダイアグノステック ソリューションズ インコーポレーテッド 抗ヒト免疫不全ウイルス－１抗体及びその使用方法
CN116143909B (zh) * 2021-11-20 2023-10-31 东莞市朋志生物科技有限公司 一种抗hiv-1 p24的抗体及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4755457A (en) * 1985-02-05 1988-07-05 Robert Guroff Marjorie Method for detecting HTLV-III neutralizing antibodies in sera
US4748110A (en) * 1985-09-25 1988-05-31 Abbott Laboratories Immunoassay for HTLV-III antigens

Also Published As

Publication number Publication date
JP3102643B2 (ja) 2000-10-23
EP0345461A3 (en) 1990-06-27
EP0345461B1 (en) 1994-09-28
DE68918497D1 (de) 1994-11-03
US5173399A (en) 1992-12-22
EP0345461A2 (en) 1989-12-13
CA1340919C (en) 2000-03-07
JPH02107196A (ja) 1990-04-19
DE68918497T2 (de) 1995-05-04

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