ES2139571T3 - Ensayo de hepatitis c que utiliza antigenos recombinantes. - Google Patents

Ensayo de hepatitis c que utiliza antigenos recombinantes.

Info

Publication number
ES2139571T3
ES2139571T3 ES91114161T ES91114161T ES2139571T3 ES 2139571 T3 ES2139571 T3 ES 2139571T3 ES 91114161 T ES91114161 T ES 91114161T ES 91114161 T ES91114161 T ES 91114161T ES 2139571 T3 ES2139571 T3 ES 2139571T3
Authority
ES
Spain
Prior art keywords
assay
recombinant antigens
hepatitis
hcv
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91114161T
Other languages
English (en)
Inventor
Sushil G Devare
Suresh M Desai
James M Casey
George J Dawson
Richard R Lesniewski
Stephen H Dailey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27075963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2139571(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2139571T3 publication Critical patent/ES2139571T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

ESTA INVENCION DESCRIBE ANTIGENOS RECOMBINANTES UNICOS, REPRESENTANDO DISTINTAS ZONAS ANTIGENICAS DEL GENOMA HCV QUE SE PUEDEN UTILIZAR COMO REACTANTES PARA DETECTAR ANTICUERPOS Y ANTIGENOS EN FLUIDOS CORPORALES DE INDIVIDUOS EXPUESTOS AL VIRUS DE LA HEPATITIS C (HCV). ESTA INVENCION DESCRIBE TAMBIEN UN ENSAYO PARA DETECTAR LA PRESENCIA DE UN ANTICUERPO PARA UN ANTIGENO HCV EN UNA MUESTRA, AL PONER EN CONTACTO LA MUESTRA CON LOS ANTIGENOS RECOMBINANTES. UNOS FORMATOS DE ENSAYO PREFERENTES, INCLUYEN UN ENSAYO TAMIZADOR, UN ENSAYO DE CONFIRMACION, UN ENSAYO DE TERMINACION O NEUTRALIZACION Y UN ENSAYO DE PUNTO INMUNOLOGICO.
ES91114161T 1990-08-24 1991-08-23 Ensayo de hepatitis c que utiliza antigenos recombinantes. Expired - Lifetime ES2139571T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57282290A 1990-08-24 1990-08-24
US61406990A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
ES2139571T3 true ES2139571T3 (es) 2000-02-16

Family

ID=27075963

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91114161T Expired - Lifetime ES2139571T3 (es) 1990-08-24 1991-08-23 Ensayo de hepatitis c que utiliza antigenos recombinantes.

Country Status (7)

Country Link
EP (1) EP0472207B1 (es)
JP (1) JP3354579B2 (es)
AT (1) ATE185605T1 (es)
AU (1) AU655592B2 (es)
CA (1) CA2049679C (es)
DE (1) DE69131707T2 (es)
ES (1) ES2139571T3 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
AU650038B2 (en) * 1988-03-11 1994-06-09 Abbott Laboratories CKS method of protein synthesis
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
US5712087A (en) * 1990-04-04 1998-01-27 Chiron Corporation Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
CA2101534C (en) * 1991-01-31 2004-01-20 Mary S. Gibadlo Monoclonal antibodies to putative hcv envelope region and methods for using same
KR0185426B1 (ko) 1991-06-24 1999-04-01 로버트 피. 블랙버언 씨형 간염 바이러스 폴리펩티드
ES2126598T3 (es) * 1991-08-21 1999-04-01 Abbott Lab Anticuerpos monoclonales que se fijan sobre las proteinas ns5 supuestas del virus de la hepatitis c, y procedimientos de utilizacion de estos anticuerpos.
JP3158177B2 (ja) * 1991-10-08 2001-04-23 国立感染症研究所長 Ｃ型肝炎診断薬
ATE219522T1 (de) * 1992-02-04 2002-07-15 Chiron Corp Hepatistherapeutikum
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
JPH06153959A (ja) * 1992-10-16 1994-06-03 Evernew Biotec Inc Ｃ型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
ES2197170T3 (es) * 1993-11-04 2004-01-01 Innogenetics N.V. Epitopos de celulas t humanas inmunologicamente dominantes del virus de la hepatitis c.
GB9513261D0 (en) * 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
US6329157B1 (en) 1998-05-28 2001-12-11 Abbott Laboratories Antigen cocktails and uses thereof
EP1082343A2 (en) * 1998-05-28 2001-03-14 Abbott Laboratories Toxoplasma gondii antigens, p35, and uses thereof
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
ES2312806T3 (es) 2002-09-09 2009-03-01 Novartis Vaccines And Diagnostics, Inc. Ensayo de vhc.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253193B1 (en) * 1986-07-08 1992-10-28 Abbott Laboratories Method for mutagenesis by oligonucleotide-directed repair of a strand break
WO1989004669A1 (en) * 1987-11-18 1989-06-01 Chiron Corporation Nanbv diagnostics and vaccines
US5124255A (en) * 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
US5075077A (en) * 1988-08-02 1991-12-24 Abbott Laboratories Test card for performing assays
HUT54896A (en) * 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
KR100206150B1 (ko) * 1990-04-04 1999-07-01 로버트 피. 블랙버언 항-에이치씨브이 항체에 대한 면역분석용 씨형 간염 바이러스(에이치디브이)항원의 조합체
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
AU2068992A (en) * 1991-08-02 1993-02-04 Akzo N.V. Non-a, non-b peptide
ZA927837B (en) * 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus

Also Published As

Publication number Publication date
EP0472207B1 (en) 1999-10-13
EP0472207A3 (en) 1992-08-26
DE69131707T2 (de) 2000-06-08
JP3354579B2 (ja) 2002-12-09
CA2049679A1 (en) 1992-02-25
EP0472207A2 (en) 1992-02-26
AU655592B2 (en) 1995-01-05
ATE185605T1 (de) 1999-10-15
AU8277491A (en) 1992-05-07
CA2049679C (en) 2005-06-21
JPH04281792A (ja) 1992-10-07
DE69131707D1 (de) 1999-11-18

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