ES2069726T3 - Anticuerpos monoclonales especificos para hirudina. - Google Patents

Anticuerpos monoclonales especificos para hirudina.

Info

Publication number
ES2069726T3
ES2069726T3 ES90810033T ES90810033T ES2069726T3 ES 2069726 T3 ES2069726 T3 ES 2069726T3 ES 90810033 T ES90810033 T ES 90810033T ES 90810033 T ES90810033 T ES 90810033T ES 2069726 T3 ES2069726 T3 ES 2069726T3
Authority
ES
Spain
Prior art keywords
monoclonal antibodies
hirudin
antibodies specific
derivatives
hirudine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90810033T
Other languages
English (en)
Other versions
ES2069726T5 (es
Inventor
Jean-Marc Dr Schlaeppi
Dietmar G Prof Dr Braun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26294877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2069726(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB898901600A external-priority patent/GB8901600D0/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2069726T3 publication Critical patent/ES2069726T3/es
Publication of ES2069726T5 publication Critical patent/ES2069726T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA LA PREPARACION DE CELULAS DE HIBRIDOMA QUE SEGREGUEN ANTICUERPOS MONOCLONALES ESPECIFICOS PARA LA HIRUDINA, LAS PROPIAS CELULAS DE HIBRIDOMA, LOS ANTICUERPOS MONOCLONALES ESPECIFICOS PARA HIRUDINA SEGREGADOS POR DICHAS CELULAS, SUS DERIVADOS Y EL PROCESO DE PREPARACION DE DICHOS ANTICUERPOS Y DERIVADOS. ESTOS ANTICUERPOS MONOCLONALES ANTI-HIRUDINA Y SUS DERIVADOS RESULTAN DE GRAN UTILIDAD EN LA DETERMINACION DE LA HIRUDINA Y COMO ANTIDOTO CONTRA LA MISMA. LA INVENCION TAMBIEN SE REFIERE A GRUPOS DE PRUEBAS Y COMPOSICIONES FARMACEUTICAS QUE CONTENGAN DICHOS ANTICUERPOS MONOCLONALES Y/O SUS DERIVADOS.
ES90810033T 1989-01-25 1990-01-16 Anticuerpos monoclonales especificos para hirudina. Expired - Lifetime ES2069726T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898901600A GB8901600D0 (en) 1989-01-25 1989-01-25 Monoclonal antibodies specific for thrombin inhibitors
GB898910713A GB8910713D0 (en) 1989-01-25 1989-05-10 Monoclonal antibodies specific for thrombin inhibitors

Publications (2)

Publication Number Publication Date
ES2069726T3 true ES2069726T3 (es) 1995-05-16
ES2069726T5 ES2069726T5 (es) 1999-09-16

Family

ID=26294877

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90810033T Expired - Lifetime ES2069726T5 (es) 1989-01-25 1990-01-16 Anticuerpos monoclonales especificos para hirudina.

Country Status (11)

Country Link
EP (1) EP0380443B2 (es)
JP (1) JP2922955B2 (es)
AT (1) ATE119195T1 (es)
AU (1) AU631173B2 (es)
CA (1) CA2008334A1 (es)
DE (1) DE69017236T3 (es)
DK (1) DK0380443T4 (es)
ES (1) ES2069726T5 (es)
GR (2) GR3015254T3 (es)
IE (1) IE65660B1 (es)
PT (1) PT92924B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296352A (en) * 1990-10-02 1994-03-22 Ciba-Geigy Corporation Monoclonal antibodies directed against complexes formed by thrombin and hirudin
DE4032127A1 (de) * 1990-10-10 1992-04-16 Basf Ag Verwendung von disulfidverbrueckten proteinen und peptiden
US6719975B1 (en) 1991-06-27 2004-04-13 Farmitalia Carlo Erba S.R.L. Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin
IT1248565B (it) * 1991-06-27 1995-01-19 Erba Carlo Spa Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l`immunopurificazione e la determinazione quantitativa dell`uridina.
AT404357B (de) * 1995-06-13 1998-11-25 Immuno Ag Prothrombin-derivate
DE19911329A1 (de) * 1998-03-27 2000-09-21 Benes Ivan Friedrich Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
DE102004054551B4 (de) * 2004-11-11 2021-07-22 Orgentec Diagnostika Gmbh Vorrichtung zur vollautomatischen Durchführung eines Einzelimmunoassays
CN103698523B (zh) * 2013-12-27 2016-01-20 常州千红生化制药股份有限公司 特异性抗rHAP单克隆抗体及其制备方法和试剂盒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3583361D1 (de) * 1984-06-14 1991-08-08 Ucp Gen Pharma Ag Verfahren zur herstellung von thrombin-inhibitoren.

Also Published As

Publication number Publication date
EP0380443B1 (en) 1995-03-01
IE65660B1 (en) 1995-11-15
AU4876590A (en) 1990-08-02
DE69017236D1 (de) 1995-04-06
JPH02299583A (ja) 1990-12-11
DE69017236T3 (de) 1999-11-25
CA2008334A1 (en) 1990-07-25
AU631173B2 (en) 1992-11-19
ES2069726T5 (es) 1999-09-16
EP0380443B2 (en) 1999-06-30
DE69017236T2 (de) 1995-07-20
DK0380443T3 (da) 1995-03-27
IE900271L (en) 1990-07-25
GR3015254T3 (en) 1995-06-30
EP0380443A3 (en) 1990-09-19
JP2922955B2 (ja) 1999-07-26
PT92924A (pt) 1990-07-31
EP0380443A2 (en) 1990-08-01
GR3030993T3 (en) 1999-12-31
ATE119195T1 (de) 1995-03-15
PT92924B (pt) 1997-08-29
DK0380443T4 (da) 1999-11-29

Similar Documents

Publication Publication Date Title
NL930094I2 (nl) Nieuwe antihistaminen, werkwijze voor de bereidingdaarvan en farmaceutische composities, die deze v erbindingen bevatten.
ATE7920T1 (de) Rapamycin-derivate.
OA05524A (fr) Procédé de préparation de compositions antibiotiques à base de 2-pyrrolidine.
DK250181A (da) Fremgangsmaade til fremstilling af vinblastinderivater
DK164703C (da) Analogifremgangsmaade til fremstilling af kvaternaere 6,11-dihydro-dibenzo-oeb,eaa-thiepin-11-n-alkyl-norscopinethere og mellemprodukt til anvendelse ved denne fremgangsmaade
IL64292A (en) D-homoandrostane-17alpha-carboxylic acids,derivatives thereof and 17alpha-spiroethers,their manufacture and pharmaceutical compositions containing them
ES2069726T5 (es) Anticuerpos monoclonales especificos para hirudina.
FI803547A7 (fi) Menetelmiä uusien piperidyylibentsimidatsolinonien valmistamiseksi.
IT8019095A0 (it) Procedimento e installazione per la fabbricazione di clincher di cementeria.
EP0660932A4 (en) METHOD FOR PRODUCING TEST ELEMENTS.
ATE71078T1 (de) Glyzerinderivate.
IL60382A0 (en) 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypiperidine compounds,their production and pharmaceutical compositions containing them
AR227176A1 (es) 3-(3-o 5-isoxazolil substituido)-1-,4-,o 5-substituidas-2-imidazolidinonas,utiles como herbicidas,composiciones que las contienen y metodo para la preparacion de dichos compuestos
IT8025261A0 (it) Procedimento per la produzione di teatrafluoruro di zolfo.
IT8026079A0 (it) Metodo per la fabbricazione di vetri fotocromici colorati.
SE8404334D0 (sv) 16-fluoro-16,17-didehydro-prostanoids and process for their preparation
DK259486A (da) Fremgangsmaade til fremstilling af 7-aca-derivater
PT86611A (pt) Process for the manufacture of n,n-(dibenzohexatrienylene)ureas
BE890307A (fr) Procede de preparation de compositions proteiques modifiees
IT1130491B (it) Procedimento per la preparazione di schiume sintetiche mediante reazioni di condensazione
ES502672A0 (es) Procedimiento para la fabricacion de articulos mediante li- tografia
AR227565A1 (es) Nuevo procedimiento de fabricacion de derivados de 5,6,7,7a-tetrahidro-4h-tieno(3,2-c)-fenilalquil-5-piridin-2-ona
DK93884A (da) Fremgangsmaade til fremstilling af 1,5-dibeskyttede-1,5,10-triazadecaner, mellemprodukter derfor samt disses fremstilling
ES2059726T3 (es) Anticuerpos monoclonales que reconocen el itsp humano, hibridomas que producen los mismos, y su preparacion y uso.
MX4573E (es) Procedimiento microbiologico para la produccion de nocardicina c d e f y g

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 380443

Country of ref document: ES