ES2071979T3 - Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales. - Google Patents

Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales.

Info

Publication number
ES2071979T3
ES2071979T3 ES91901884T ES91901884T ES2071979T3 ES 2071979 T3 ES2071979 T3 ES 2071979T3 ES 91901884 T ES91901884 T ES 91901884T ES 91901884 T ES91901884 T ES 91901884T ES 2071979 T3 ES2071979 T3 ES 2071979T3
Authority
ES
Spain
Prior art keywords
biological fluids
connective tissues
bone
humans
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91901884T
Other languages
English (en)
Inventor
Simon Peter Robins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rowett Research Institute
Original Assignee
Rowett Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rowett Research Institute filed Critical Rowett Research Institute
Application granted granted Critical
Publication of ES2071979T3 publication Critical patent/ES2071979T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/108—Osteoporosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Window Of Vehicle (AREA)
  • Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
  • Mechanical Coupling Of Light Guides (AREA)

Abstract

METODO PARA DETECTAR TRASTORNOS EN LOS HUESOS Y EN OTROS TEJIDOS CONECTIVOS EN SERES HUMANOS Y ANIMALES LA INVENCION SE REFIERE A METODOS PARA DETERMINAR EL METABOLISMO DEL TEJIDO CONECTIVO, EN ESPECIAL DE LOS HUESOS, O CONTROLAR LA TERAPIA, CUYO METODO CONSISTE EN DETERMINAR LOS NIVELES DE ENLACES EN CRUZ DERIVADOS DEL COLAGENO LIBRE NATIVO EN FLUIDOS BIOLOGICOS, ESPECIALMENTE EN LA ORINA. EL METODO SE PUEDE MEJORAR SI SE DETERMINAN AL MISMO TIEMPO LOS NIVELES DE UN INDICADOR DE LA FORMACION DE LOS HUESOS EN FLUIDOS BIOLOGICOS DEL MISMO INDIVIDUO Y LAS DIFERENCIAS ENTRE EL MARCADOR DE LA DEGRADACION Y EL INDICADOR DE LA FORMACION. SE PRESENTAN TAMBIEN LOS ANTICUERPOS QUE SON ESPECIFICAMENTE INMUNORREACTIVOS CON FORMAS DE ENLACES EN CRUZ QUE OCURREN DE MANERA LIBRE EN LOS FLUIDOS BIOLOGICOS.
ES91901884T 1989-12-30 1990-12-28 Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales. Expired - Lifetime ES2071979T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929366A GB8929366D0 (en) 1989-12-30 1989-12-30 Method to detect connective tissue disorder in humans and animals

Publications (1)

Publication Number Publication Date
ES2071979T3 true ES2071979T3 (es) 1995-07-01

Family

ID=10668604

Family Applications (2)

Application Number Title Priority Date Filing Date
ES91901884T Expired - Lifetime ES2071979T3 (es) 1989-12-30 1990-12-28 Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales.
ES94108293T Expired - Lifetime ES2147761T3 (es) 1989-12-30 1990-12-28 Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES94108293T Expired - Lifetime ES2147761T3 (es) 1989-12-30 1990-12-28 Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales.

Country Status (17)

Country Link
US (2) US5700693A (es)
EP (2) EP0507831B1 (es)
JP (3) JPH087212B2 (es)
KR (1) KR0138503B1 (es)
AT (2) ATE191976T1 (es)
AU (2) AU648774B2 (es)
BR (1) BR9007969A (es)
CA (2) CA2271544C (es)
DE (2) DE69019375T2 (es)
DK (1) DK0507831T3 (es)
ES (2) ES2071979T3 (es)
FI (1) FI923028A7 (es)
GB (1) GB8929366D0 (es)
GR (1) GR3016998T3 (es)
HU (1) HUT64421A (es)
NO (1) NO304760B1 (es)
WO (1) WO1991010141A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121002A (en) * 1990-12-26 2000-09-19 The Rowett Research Institute Method to detect bone and other connective tissue disorders in humans and animals
GB9202139D0 (en) * 1992-01-31 1992-03-18 Sandoz Ltd Improvements in or relating to organic compounds
EP0561297B1 (en) * 1992-03-19 1998-10-14 Hoechst Marion Roussel, Ltd. Tissue antigen and diagnostic method for human osteoporosis using the same
US5620861A (en) * 1992-07-31 1997-04-15 Metra Biosystems, Inc. Method and kit for pyridinium crosslink assay
US5527715A (en) * 1992-07-31 1996-06-18 Metra Biosystems, Inc. Method and kit for pyridinoline assay
WO1994006015A1 (en) * 1992-08-28 1994-03-17 The Rowett Research Institute Method to monitor drug therapy and assess metastasis
US5756361A (en) * 1992-12-17 1998-05-26 Metra Biosystems, Inc. Screening method for periodontal disease
US5736344A (en) * 1992-12-17 1998-04-07 Metra Biosystems, Inc. Serum pyridinium crosslinks assay
JPH0792165A (ja) * 1993-09-21 1995-04-07 Hoechst Japan Ltd 骨粗鬆症診断剤
US5661039A (en) * 1995-03-01 1997-08-26 Metra Biosystems, Inc. Perspiration assay for bone resorption
DE69821246T2 (de) * 1997-07-31 2004-11-04 Metra Biosystems, Inc., Mountain View Testverfahren für collagenpeptid
US6033918A (en) * 1997-11-10 2000-03-07 Bayer Corporation Method and device for the detection of analyte in a fluid sample
AU3035699A (en) * 1998-03-27 1999-10-18 Seibel, Markus Determination of the probability of bone metastases in patients with primary carcinomas
US6197592B1 (en) * 1999-07-15 2001-03-06 Bio-Rad Laboratories, Inc. Clinical control materials for detection of bone resorptive markers
AU2001293964B2 (en) 2000-10-03 2007-06-14 Rowett Research Institute Method of assaying pyrrole-containing biological compounds
JP7575824B1 (ja) * 2023-12-19 2024-10-30 株式会社DeVine 哺乳動物の歯に含まれるコラーゲンの所定の定量値を用いる方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
GB8815174D0 (en) * 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
US5283197A (en) * 1988-06-25 1994-02-01 The Rowett Research Institute Method of monitoring collagen degradation
GB8927377D0 (en) * 1989-12-04 1990-01-31 Univ Edinburgh Improvements in and relating to amperometric assays
US5620861A (en) * 1992-07-31 1997-04-15 Metra Biosystems, Inc. Method and kit for pyridinium crosslink assay
FI106326B (fi) * 1996-09-23 2001-01-15 Tellabs Oy Kytkentä kaiunpoistavan moninopeusmodeemin sovittamiseksi linjalle sekä kytkentämenetelmä

Also Published As

Publication number Publication date
EP0507831A1 (en) 1992-10-14
CA2271544A1 (en) 1991-07-01
DE69033511T2 (de) 2000-11-16
BR9007969A (pt) 1993-02-02
FI923028A0 (fi) 1992-06-30
AU7065991A (en) 1991-07-24
JP3224356B2 (ja) 2001-10-29
JPH1045800A (ja) 1998-02-17
NO304760B1 (no) 1999-02-08
AU648774B2 (en) 1994-05-05
CA2069611A1 (en) 1991-07-01
AU6864894A (en) 1994-11-24
DE69019375T2 (de) 1995-09-14
US5700693A (en) 1997-12-23
GB8929366D0 (en) 1990-02-28
DE69033511D1 (de) 2000-05-25
NO922573D0 (no) 1992-06-29
AU682188B2 (en) 1997-09-25
HUT64421A (en) 1993-12-28
ATE191976T1 (de) 2000-05-15
US5700694A (en) 1997-12-23
HU9202178D0 (en) 1992-10-28
JPH05502942A (ja) 1993-05-20
JP2001050958A (ja) 2001-02-23
EP0618448A1 (en) 1994-10-05
JPH087212B2 (ja) 1996-01-29
EP0618448B1 (en) 2000-04-19
WO1991010141A1 (en) 1991-07-11
NO922573L (no) 1992-06-29
ATE122467T1 (de) 1995-05-15
GR3016998T3 (en) 1995-11-30
DE69019375D1 (de) 1995-06-14
FI923028L (fi) 1992-06-30
DK0507831T3 (da) 1995-10-09
FI923028A7 (fi) 1992-06-30
KR0138503B1 (en) 1998-05-15
EP0507831B1 (en) 1995-05-10
CA2271544C (en) 2006-01-17
CA2069611C (en) 1999-08-10
ES2147761T3 (es) 2000-10-01

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