ES2147761T3 - Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales. - Google Patents

Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales.

Info

Publication number
ES2147761T3
ES2147761T3 ES94108293T ES94108293T ES2147761T3 ES 2147761 T3 ES2147761 T3 ES 2147761T3 ES 94108293 T ES94108293 T ES 94108293T ES 94108293 T ES94108293 T ES 94108293T ES 2147761 T3 ES2147761 T3 ES 2147761T3
Authority
ES
Spain
Prior art keywords
bones
biological fluids
humans
alterations
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94108293T
Other languages
English (en)
Inventor
Simon Robins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rowett Research Institute
Original Assignee
Rowett Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rowett Research Institute filed Critical Rowett Research Institute
Application granted granted Critical
Publication of ES2147761T3 publication Critical patent/ES2147761T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/108—Osteoporosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
  • Window Of Vehicle (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A ANTICUERPOS QUE SON ESPECIFICAMENTE INMUNORREACTIVOS CON FORMAS DE ENTRECRUZAMIENTOS QUE OCURREN DE FORMA LIBRE EN FLUIDOS BIOLOGICOS. TAMBIEN SE PRESENTAN LOS METODOS PARA EVALUAR UN METABOLISMO DEL TEJIDO CONECTIVO, ESPECIALMENTE DE LOS HUESOS, ENFERMO O PARA CONTROLAR UNA TERAPIA. TALES METODOS CONSISTEN EN EVALUAR LOS NIVELES DE ENTRECRUZAMIENTOS EN FLUIDOS BIOLOGICOS DERIVADOS DE COLAGENOS QUE OCURREN DE FORMA NATURAL, ESPECIALMENTE DE LA ORINA. EL METODO SE PUEDE MEJORAR SI SE DETERMINAN DE FORMA CONCOMITANTE LOS NIVELES DE UN INDICADOR DE LA FORMACION DE LOS HUESOS EN FLUIDOS BIOLOGICOS DEL MISMO INDIVIDUO Y SE EVALUAN LAS DIFERENCIAS ENTRE LA MARCADOR DE DEGRADACION Y EL INDICADOR DE LA FORMACION.
ES94108293T 1989-12-30 1990-12-28 Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales. Expired - Lifetime ES2147761T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929366A GB8929366D0 (en) 1989-12-30 1989-12-30 Method to detect connective tissue disorder in humans and animals

Publications (1)

Publication Number Publication Date
ES2147761T3 true ES2147761T3 (es) 2000-10-01

Family

ID=10668604

Family Applications (2)

Application Number Title Priority Date Filing Date
ES94108293T Expired - Lifetime ES2147761T3 (es) 1989-12-30 1990-12-28 Metodo para la deteccion de alteraciones de los huesos y otros tejidos conectivos en los seres humanos y los animales.
ES91901884T Expired - Lifetime ES2071979T3 (es) 1989-12-30 1990-12-28 Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES91901884T Expired - Lifetime ES2071979T3 (es) 1989-12-30 1990-12-28 Metodo para detectar alteraciones en el hueso y en otros tejidos conectivos en humanos y animales.

Country Status (17)

Country Link
US (2) US5700694A (es)
EP (2) EP0618448B1 (es)
JP (3) JPH087212B2 (es)
KR (1) KR0138503B1 (es)
AT (2) ATE122467T1 (es)
AU (2) AU648774B2 (es)
BR (1) BR9007969A (es)
CA (2) CA2271544C (es)
DE (2) DE69033511T2 (es)
DK (1) DK0507831T3 (es)
ES (2) ES2147761T3 (es)
FI (1) FI923028A0 (es)
GB (1) GB8929366D0 (es)
GR (1) GR3016998T3 (es)
HU (1) HUT64421A (es)
NO (1) NO304760B1 (es)
WO (1) WO1991010141A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121002A (en) * 1990-12-26 2000-09-19 The Rowett Research Institute Method to detect bone and other connective tissue disorders in humans and animals
GB9202139D0 (en) * 1992-01-31 1992-03-18 Sandoz Ltd Improvements in or relating to organic compounds
DE69321503T2 (de) * 1992-03-19 1999-05-06 Hoechst Marion Roussel, Ltd., Tokio/Tokyo Gewebeantigen und seine Anwendung in einem Nachweisverfahren von humaner Osteoporose
US5527715A (en) * 1992-07-31 1996-06-18 Metra Biosystems, Inc. Method and kit for pyridinoline assay
US5620861A (en) * 1992-07-31 1997-04-15 Metra Biosystems, Inc. Method and kit for pyridinium crosslink assay
AU2481992A (en) * 1992-08-28 1994-03-29 Rowett Research Institute, The Method to monitor drug therapy and assess metastasis
US5756361A (en) * 1992-12-17 1998-05-26 Metra Biosystems, Inc. Screening method for periodontal disease
US5736344A (en) * 1992-12-17 1998-04-07 Metra Biosystems, Inc. Serum pyridinium crosslinks assay
JPH0792165A (ja) * 1993-09-21 1995-04-07 Hoechst Japan Ltd 骨粗鬆症診断剤
US5661039A (en) * 1995-03-01 1997-08-26 Metra Biosystems, Inc. Perspiration assay for bone resorption
US5972623A (en) * 1997-07-31 1999-10-26 Metra Biosystems, Inc. Collagen-peptide assay method
US6033918A (en) * 1997-11-10 2000-03-07 Bayer Corporation Method and device for the detection of analyte in a fluid sample
AU3035699A (en) * 1998-03-27 1999-10-18 Seibel, Markus Determination of the probability of bone metastases in patients with primary carcinomas
US6197592B1 (en) * 1999-07-15 2001-03-06 Bio-Rad Laboratories, Inc. Clinical control materials for detection of bone resorptive markers
AU2001293964B2 (en) * 2000-10-03 2007-06-14 Rowett Research Institute Method of assaying pyrrole-containing biological compounds
JP7575824B1 (ja) * 2023-12-19 2024-10-30 株式会社DeVine 哺乳動物の歯に含まれるコラーゲンの所定の定量値を用いる方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300434A (en) * 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
GB8815174D0 (en) * 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
US5283197A (en) * 1988-06-25 1994-02-01 The Rowett Research Institute Method of monitoring collagen degradation
GB8927377D0 (en) * 1989-12-04 1990-01-31 Univ Edinburgh Improvements in and relating to amperometric assays
US5620861A (en) * 1992-07-31 1997-04-15 Metra Biosystems, Inc. Method and kit for pyridinium crosslink assay
FI106326B (fi) * 1996-09-23 2001-01-15 Tellabs Oy Kytkentä kaiunpoistavan moninopeusmodeemin sovittamiseksi linjalle sekä kytkentämenetelmä

Also Published As

Publication number Publication date
JPH087212B2 (ja) 1996-01-29
DK0507831T3 (da) 1995-10-09
HUT64421A (en) 1993-12-28
GB8929366D0 (en) 1990-02-28
NO922573L (no) 1992-06-29
GR3016998T3 (en) 1995-11-30
KR0138503B1 (en) 1998-05-15
JP3224356B2 (ja) 2001-10-29
FI923028L (fi) 1992-06-30
FI923028A7 (fi) 1992-06-30
DE69033511D1 (de) 2000-05-25
US5700693A (en) 1997-12-23
JPH05502942A (ja) 1993-05-20
AU6864894A (en) 1994-11-24
CA2271544C (en) 2006-01-17
ES2071979T3 (es) 1995-07-01
HU9202178D0 (en) 1992-10-28
NO304760B1 (no) 1999-02-08
DE69033511T2 (de) 2000-11-16
JP2001050958A (ja) 2001-02-23
EP0618448A1 (en) 1994-10-05
WO1991010141A1 (en) 1991-07-11
CA2069611C (en) 1999-08-10
JPH1045800A (ja) 1998-02-17
EP0507831B1 (en) 1995-05-10
ATE191976T1 (de) 2000-05-15
EP0618448B1 (en) 2000-04-19
BR9007969A (pt) 1993-02-02
DE69019375D1 (de) 1995-06-14
CA2069611A1 (en) 1991-07-01
CA2271544A1 (en) 1991-07-01
NO922573D0 (no) 1992-06-29
EP0507831A1 (en) 1992-10-14
FI923028A0 (fi) 1992-06-30
DE69019375T2 (de) 1995-09-14
AU7065991A (en) 1991-07-24
ATE122467T1 (de) 1995-05-15
AU682188B2 (en) 1997-09-25
AU648774B2 (en) 1994-05-05
US5700694A (en) 1997-12-23

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