ES2075831T3 - Regulacion antisentido de expresion genica vegetal. - Google Patents

Regulacion antisentido de expresion genica vegetal.

Info

Publication number
ES2075831T3
ES2075831T3 ES87309853T ES87309853T ES2075831T3 ES 2075831 T3 ES2075831 T3 ES 2075831T3 ES 87309853 T ES87309853 T ES 87309853T ES 87309853 T ES87309853 T ES 87309853T ES 2075831 T3 ES2075831 T3 ES 2075831T3
Authority
ES
Spain
Prior art keywords
gene expression
plant gene
sense regulation
arn
base sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87309853T
Other languages
English (en)
Inventor
Ian George Bridges
Wolfgang Walter Schuch
Donald Grierson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10607120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2075831(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of ES2075831T3 publication Critical patent/ES2075831T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8249—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving ethylene biosynthesis, senescence or fruit development, e.g. modified tomato ripening, cut flower shelf-life
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01011—Pectinesterase (3.1.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01015—Polygalacturonase (3.2.1.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Preparation Of Fruits And Vegetables (AREA)

Abstract

EL ADN RECOMBINANTE COMPRENDE SECUENCIAS BASE PROMOTORA Y TERMINADORA RESPECTIVAMENTE HACIA DELANTE Y HACIA DETRAS DE UNA SECUENCIA BASE INVERTIDA COMPLEMENTARIA A UNA SECUENCIA SUSTANCIAL DE BASES EN EL M-ARN DE POLIGALACTURONASA. EL M-ARN COMPLEMENTARIO PRODUCIDO ASI RETARDA EL REBLANDECIMIENTO DE FRUTOS, EN PARTICULAR DE TOMATES.
ES87309853T 1986-11-11 1987-11-06 Regulacion antisentido de expresion genica vegetal. Expired - Lifetime ES2075831T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868626879A GB8626879D0 (en) 1986-11-11 1986-11-11 Dna

Publications (1)

Publication Number Publication Date
ES2075831T3 true ES2075831T3 (es) 1995-10-16

Family

ID=10607120

Family Applications (2)

Application Number Title Priority Date Filing Date
ES87309853T Expired - Lifetime ES2075831T3 (es) 1986-11-11 1987-11-06 Regulacion antisentido de expresion genica vegetal.
ES92117411T Expired - Lifetime ES2149162T3 (es) 1986-11-11 1987-11-06 Regulacion anti-sentido de la expresion de genes de plantas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES92117411T Expired - Lifetime ES2149162T3 (es) 1986-11-11 1987-11-06 Regulacion anti-sentido de la expresion de genes de plantas.

Country Status (9)

Country Link
US (3) US5073676A (es)
EP (2) EP0532060B1 (es)
JP (1) JP3098238B2 (es)
AT (2) ATE126536T1 (es)
AU (4) AU643184B2 (es)
DE (2) DE3751466T2 (es)
ES (2) ES2075831T3 (es)
GB (1) GB8626879D0 (es)
GR (2) GR3017148T3 (es)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81737A (en) * 1986-03-28 1992-11-15 Calgene Inc Regulation of gene expression in plant cells
US5453566A (en) * 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US5107065A (en) * 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5296376A (en) * 1986-11-04 1994-03-22 Imperial Chemical Industries Plc DNA, constructs, cells and plants derived therefrom
GB8927048D0 (en) * 1989-11-30 1990-01-31 Ici Plc Dna,constructs,cells and plants derived therefrom
GB8626879D0 (en) * 1986-11-11 1986-12-10 Ici Plc Dna
US6271033B1 (en) 1986-11-11 2001-08-07 Zeneca Limited Method for modifying production of fruit ripening enzyme
NZ224787A (en) * 1987-05-26 1990-08-28 Calgene Inc A dna construct for specifically modifying the phenotype of fruit as distinct from other plant tissue
GB8811115D0 (en) * 1988-05-11 1988-06-15 Ici Plc Tomatoes
US6054566A (en) 1988-02-26 2000-04-25 Biosource Technologies, Inc. Recombinant animal viral nucleic acids
US5316931A (en) * 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US6284492B1 (en) 1988-02-26 2001-09-04 Large Scale Biology Corporation Recombinant animal viral nucleic acids
NL8800756A (nl) * 1988-03-25 1989-10-16 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Genetisch gemanipuleerde plantecellen en planten, alsmede daarvoor bruikbaar recombinant dna.
DE3908813A1 (de) * 1989-03-17 1990-09-20 Roehm Gmbh Verfahren zur expression eines aus aspergillus niger stammenden gens in einem aspergillus
GB8916213D0 (en) * 1989-07-14 1989-08-31 Ici Plc Dna constructs,cells and plants derived therefrom
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
DE3929741A1 (de) * 1989-09-07 1991-03-28 Hoechst Ag Rna mit endoribonucleaseaktivitaet gegen mrna von reifungsgenen, ihre herstellung und ihre verwendung in pflanzen
US5744364A (en) * 1989-10-20 1998-04-28 Zeneca Limited PTOM36 constructs and tomato cells transformed therewith
GB8923716D0 (en) * 1989-10-20 1989-12-06 Ici Plc Dna,constructs,cells and plants derived therefrom
GB8928179D0 (en) * 1989-12-13 1990-02-14 Ici Plc Dna,constructs,cells and plants derived therefrom
ES2163392T3 (es) * 1990-03-16 2002-02-01 Calgene Llc Nuevas secuencias expresadas preferentemente en el desarrollo de semillas precoces, y procedimientos relacionados con las mismas.
US5585545A (en) * 1990-04-20 1996-12-17 The Regents Of The University Of California Endo-1,4-β-glucanase genes and their use in plants
US5168064A (en) * 1990-04-20 1992-12-01 The Regents Of The University Of California Endo-1,4-β-glucanase gene and its use in plants
GB9009307D0 (en) * 1990-04-25 1990-06-20 Ici Plc Dna,constructs,cells and plant derived therefrom
GB9021923D0 (en) * 1990-10-09 1990-11-21 Ici Plc Dna,dna constructs,cells and plants derived therefrom
GB9024323D0 (en) * 1990-11-08 1990-12-19 Ici Plc Regulation of gene expression
US5260205A (en) * 1990-11-14 1993-11-09 Philip Morris Incorporated Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine
US5585542A (en) * 1990-12-21 1996-12-17 Commonwealth Scientific And Industrial Research Organisation DNA sequences encoding at least part of the tomato enzyme endopolygalacturonase PG1 β-subunit
CA2096637A1 (en) * 1990-12-26 1992-06-27 Harry J. Klee Control of fruit ripening and senescence in plants
GB9105420D0 (en) * 1991-03-14 1991-05-01 Ici Plc Expression of genes in transgenic plants
GB9127098D0 (en) * 1991-12-20 1992-02-19 Ici Plc Dna,dna constructs,cells and plants derived therefrom
ZA933177B (en) * 1992-05-08 1996-02-09 Univ Arizona Transgenic tomato plants with altered polygalacturonase isoforms
GB9210273D0 (en) * 1992-05-13 1992-07-01 Ici Plc Dna
US5955652A (en) * 1992-06-16 1999-09-21 The Trustees Of The University Of Pennsylvania Plant genes for sensitivity to ethylene and pathogens
US5367065A (en) * 1992-08-10 1994-11-22 The Trustees Of The University Of Pennsylvania Constitutive triple response gene and mutations
ATE312510T1 (de) * 1992-06-29 2005-12-15 Gene Shears Pty Ltd Nukleinsäuren und sie verwendende verfahren zur bekämpfung viraler pathogene
WO1994005795A1 (en) * 1992-08-27 1994-03-17 Commonwealth Scientific And Industrial Research Organisation Dna sequences encoding peach polygalacturonase
EP0674708A4 (en) * 1992-12-15 1996-07-24 Commw Scient Ind Res Org DNA MOLECULES WHICH CODE ADH2 ENZYMES FOR INDUCABLE PLANT PROMOTORS AND TOMATOES.
US5534660A (en) * 1993-04-16 1996-07-09 Dna Plant Technology Corporation Ph genes and their uses
GB9506684D0 (en) * 1995-03-31 1995-05-24 Nickerson Biocem Ltd Control of pod dehiscence
EP0853676B1 (en) * 1995-10-06 2006-06-21 Bayer BioScience N.V. Seed shattering
GB9521848D0 (en) * 1995-10-25 1996-01-03 Zeneca Ltd Modification of lignin synthesis in plants
US6452067B1 (en) 1997-09-19 2002-09-17 Dna Plant Technology Corporation Methods to assay for post-transcriptional suppression of gene expression
DE69933856D1 (de) * 1998-02-13 2006-12-14 Koester Hubert Verwendung von ribozymen zur bestimmung der funktion von genen
GB9810159D0 (en) * 1998-05-12 1998-07-08 Danisco Short amino acid sequence
US20050086718A1 (en) 1999-03-23 2005-04-21 Mendel Biotechnology, Inc. Plant transcriptional regulators of abiotic stress
US7897843B2 (en) 1999-03-23 2011-03-01 Mendel Biotechnology, Inc. Transcriptional regulation of plant biomass and abiotic stress tolerance
US6441272B1 (en) 1998-12-02 2002-08-27 The University Of Georgia Research Foundation, Inc. Modification of lignin content and composition in plants
GB9914209D0 (en) * 1999-06-17 1999-08-18 Danisco Process
CA2364983A1 (en) * 2000-12-13 2002-06-13 John R. Coleman Nucleic acid molecules and polypeptides for catabolism of abscisic acid
US20040191790A1 (en) * 2001-05-04 2004-09-30 Tomassen Monica Magdalena Maria Novel regulatory protein
US7230168B2 (en) 2001-12-20 2007-06-12 The Curators Of The University Of Missouri Reversible male sterility in transgenic plants by expression of cytokinin oxidase
KR20030073033A (ko) * 2002-03-08 2003-09-19 이채붕 치과기공용 서멀툴 어셈블리
US20040052161A1 (en) * 2002-09-17 2004-03-18 Steven Liao Mechanical clock having wireless manipulation and adjustment function
PT1546336E (pt) 2002-09-18 2012-04-09 Mendel Biotechnology Inc Polinucleótidos e polipéptidos em plantas
US20040250322A1 (en) 2002-10-22 2004-12-09 Anawah, Inc. Tomatoes having reduced polygalacturonase activity caused by non-transgenic mutations in the polygalacturonase gene
US7365186B2 (en) 2002-11-22 2008-04-29 Arborgen, Llc Vascular-preferred promoter sequences and uses thereof
EP1639081A4 (en) 2003-06-06 2007-11-07 Arborgen Llc COMPOSITIONS AND METHOD FOR REGULATING POLYSACCHARIDES OF A PLANT CELL
AR047574A1 (es) 2003-12-30 2006-01-25 Arborgen Llc 2 Genesis Res 1 Genes del ciclo celular y metodos de uso relacionados
US7456338B2 (en) 2004-09-22 2008-11-25 Arborgen Llc Modification of plant lignin content
US7799906B1 (en) 2004-09-22 2010-09-21 Arborgen, Llc Compositions and methods for modulating lignin of a plant
US7402428B2 (en) 2004-09-22 2008-07-22 Arborgen, Llc Modification of plant lignin content
US7453025B2 (en) 2004-09-22 2008-11-18 Arborgen, Llc Reproductive ablation constructs
US20110088126A1 (en) 2005-06-17 2011-04-14 Arborgen, Llc Cell signaling genes and related methods
WO2012142106A1 (en) 2011-04-11 2012-10-18 Targeted Growth, Inc. Identification and the use of krp mutants in plants
US9988641B2 (en) 2016-04-05 2018-06-05 Corn Products Development, Inc. Compositions and methods for producing starch with novel functionality
ES2983336T3 (es) 2017-09-18 2024-10-22 Futuragene Israel Ltd Control de la expresión de polipéptidos DELLA en tejidos específicos
CN110393809A (zh) * 2019-07-29 2019-11-01 天津大学 一种纳米级磁共振成像造影剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81737A (en) * 1986-03-28 1992-11-15 Calgene Inc Regulation of gene expression in plant cells
US4801540A (en) * 1986-10-17 1989-01-31 Calgene, Inc. PG gene and its use in plants
GB8626879D0 (en) * 1986-11-11 1986-12-10 Ici Plc Dna
NZ224787A (en) * 1987-05-26 1990-08-28 Calgene Inc A dna construct for specifically modifying the phenotype of fruit as distinct from other plant tissue

Also Published As

Publication number Publication date
AU663811B2 (en) 1995-10-19
DE3751466T2 (de) 1996-01-18
GR3034607T3 (en) 2001-01-31
AU5263293A (en) 1994-03-17
AU643184B2 (en) 1993-11-11
JP3098238B2 (ja) 2000-10-16
EP0532060B1 (en) 2000-07-12
EP0271988A3 (en) 1989-04-26
ATE194655T1 (de) 2000-07-15
AU2831295A (en) 1996-01-04
EP0271988B1 (en) 1995-08-16
US5457281A (en) 1995-10-10
ES2149162T3 (es) 2000-11-01
JPS63164892A (ja) 1988-07-08
AU7435091A (en) 1991-07-11
ATE126536T1 (de) 1995-09-15
GB8626879D0 (en) 1986-12-10
AU633202B2 (en) 1993-01-21
DE3752317D1 (de) 2000-08-17
DE3752317T2 (de) 2000-11-30
DE3751466D1 (de) 1995-09-21
EP0271988A2 (en) 1988-06-22
US5073676A (en) 1991-12-17
EP0532060A1 (en) 1993-03-17
GR3017148T3 (en) 1995-11-30
AU8095687A (en) 1988-05-12
US5447867A (en) 1995-09-05

Similar Documents

Publication Publication Date Title
ES2149162T3 (es) Regulacion anti-sentido de la expresion de genes de plantas.
ES2066759T3 (es) Regulador antisentido de la expresion de un gen en celulas de plantas.
IL96768A (en) Site-specific recombination of dna in plant cells
BG91270A (bg) Антивирусно и антибактериално средство и метод за използването му
DK289688A (da) Ekspression af proapolipoprotein a-i.
ES2163864T3 (es) Secuencias de dna de 2-desoxiglucosa-6-fosfato (2-dog-6-p) como marcador de seleccion en plantas.
ES2154624T1 (es) Regulacion de la expresion de la quinolato fosforribosil transferasa.
EP0237966A3 (en) Human basic fibroblast growth factor
DE68923903D1 (de) Tomaten.
IL75963A0 (en) Interferon derivatives,their preparation and pharmaceutical compositions containing them
ES2104596T3 (es) Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.
DK0889957T3 (da) Subtilisindimer med forbedret aktivitet og fremgangsmåde til fremstilling deraf
NZ230654A (en) Anti-cell proliferative penta and hexa peptides
ATE108831T1 (de) Rinder-interleukin-1-alpha.
ES470340A1 (es) Un metodo para obtener una cepa de microorganismos modifica-dos para contener un fragmento de una secuencia especifica de desoxiribonucleotidos
ES8707554A1 (es) Procedimiento para preparar interferon-a recombinante
ES2080486T3 (es) Sg(beta)-1,4-galactanasa y una secuencia de adn.
DK62985D0 (da) Polypeptid
RU94045821A (ru) Трансгенные растения, проявляющие множественную устойчивость к вирусу, и способ их получения
ES2062006T3 (es) Un psti humano modificado.
DE3669333D1 (de) Einteilige kunststoffwaescheklammer.
DE68929340D1 (de) Pflanzenverlängerungsfaktor, promotoren, kodierende sequenzen und verwendungen
EP0254905A3 (en) Shiga vaccine
AR021842A1 (es) Un vector, un metodo para producir celulas transformadas, una celula transformada y metodo de expresion de un gen.
BR8800369A (pt) Vaso para cultivar artigos comerciais originais tais como pequenas gemas preciosas e semelhantes,e processo para cultivo controlado de artigos comerciais em meio de plantio

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 271988

Country of ref document: ES