ES2080717T3 - Hibridomas productores de anticuerpos monoclonales para nuevos epitopos de mucina. - Google Patents

Hibridomas productores de anticuerpos monoclonales para nuevos epitopos de mucina.

Info

Publication number
ES2080717T3
ES2080717T3 ES87116997T ES87116997T ES2080717T3 ES 2080717 T3 ES2080717 T3 ES 2080717T3 ES 87116997 T ES87116997 T ES 87116997T ES 87116997 T ES87116997 T ES 87116997T ES 2080717 T3 ES2080717 T3 ES 2080717T3
Authority
ES
Spain
Prior art keywords
epitopes
new
monoclonal antibodies
producing monoclonal
mucina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87116997T
Other languages
English (en)
Other versions
ES2080717T5 (es
Inventor
Peter S Linsley
Diane Horn
Joseph P Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26801637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2080717(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of ES2080717T3 publication Critical patent/ES2080717T3/es
Application granted granted Critical
Publication of ES2080717T5 publication Critical patent/ES2080717T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

NUEVAS LINEAS DE CELULAS DE HIBRIDOMAS QUE PRODUCEN ANTICUERPOS MONOCLONALES REACTIVOS CON ANTIGENOS DE MUCINA PURIFICADOS A PARTIR DE FUENTES NORMALES Y TUMORALES. SE GENERAN EMPLEANDO MUCINAS, INCLUYENDO MUCINAS PURIFICADAS A PARTIR DE FUENTES TUMORALES. SE DEMUESTRA QUE LOS EPITOPES SOBRE ANTIGENOS DE MUCINA DE FUENTES NORMALES Y TUMORALES, SON DISTINTOS, UTILIZANDO ESTOS NUEVOS ANTICUERPOS. LOS ANTICUERPOS PUEDEN SER UTILES SOLOS O EN COMBINACION, EN EL DIAGNOSTICO Y TRATAMIENTO DEL CANCER INCLUYENDO TUMORES MALIGNOS DEL PECHO Y PULMONES.
ES87116997T 1986-11-19 1987-11-17 Hibridomas productores de anticuerpos monoclonales para nuevos epitopos de mucina. Expired - Lifetime ES2080717T5 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93278186A 1986-11-19 1986-11-19
US932781 1986-11-19
US10451187A 1987-10-08 1987-10-08
US104511 1987-10-08

Publications (2)

Publication Number Publication Date
ES2080717T3 true ES2080717T3 (es) 1996-02-16
ES2080717T5 ES2080717T5 (es) 2004-07-16

Family

ID=26801637

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87116997T Expired - Lifetime ES2080717T5 (es) 1986-11-19 1987-11-17 Hibridomas productores de anticuerpos monoclonales para nuevos epitopos de mucina.

Country Status (16)

Country Link
US (1) US5849876A (es)
EP (1) EP0268279B2 (es)
JP (1) JP2597372B2 (es)
KR (1) KR900007951B1 (es)
AT (1) ATE130029T1 (es)
AU (1) AU613590B2 (es)
CA (1) CA1340815C (es)
DE (1) DE3751585T3 (es)
DK (1) DK175635B1 (es)
ES (1) ES2080717T5 (es)
GR (1) GR3018093T3 (es)
IE (1) IE71154B1 (es)
IL (1) IL84475A (es)
NO (1) NO175944C (es)
NZ (1) NZ222509A (es)
PT (1) PT86180B (es)

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US20060210474A1 (en) * 2000-11-29 2006-09-21 Young David S Cytotoxicity mediation of cells evidencing surface expression of CD63
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US7175846B2 (en) * 2003-01-21 2007-02-13 Arius Research Inc. Cancerous disease modifying antibodies
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Also Published As

Publication number Publication date
NO874796L (no) 1988-05-20
DE3751585T2 (de) 1996-04-25
US5849876A (en) 1998-12-15
NO175944B (no) 1994-09-26
JP2597372B2 (ja) 1997-04-02
NO175944C (no) 1995-01-04
DK606287D0 (da) 1987-11-18
NO874796D0 (no) 1987-11-18
DK175635B1 (da) 2004-12-27
JPS63279784A (ja) 1988-11-16
IE873110L (en) 1988-05-19
AU613590B2 (en) 1991-08-08
CA1340815C (en) 1999-11-09
HK1007766A1 (en) 1999-04-23
PT86180A (en) 1987-12-01
EP0268279B2 (en) 2003-12-03
IL84475A (en) 1992-06-21
KR880006358A (ko) 1988-07-22
KR900007951B1 (ko) 1990-10-23
PT86180B (pt) 1990-11-07
DK606287A (da) 1988-05-20
GR3018093T3 (en) 1996-02-29
ES2080717T5 (es) 2004-07-16
NZ222509A (en) 1993-03-26
EP0268279A3 (en) 1991-07-03
DE3751585D1 (de) 1995-12-14
EP0268279B1 (en) 1995-11-08
DE3751585T3 (de) 2004-08-05
IE71154B1 (en) 1997-01-29
EP0268279A2 (en) 1988-05-25
IL84475A0 (en) 1988-04-29
ATE130029T1 (de) 1995-11-15
AU8099487A (en) 1988-06-09

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