ES2089232T3 - 5-enolpiruvilsiquimato-3-fosfato sintasas tolerantes del glifosato. - Google Patents
5-enolpiruvilsiquimato-3-fosfato sintasas tolerantes del glifosato.Info
- Publication number
- ES2089232T3 ES2089232T3 ES91917090T ES91917090T ES2089232T3 ES 2089232 T3 ES2089232 T3 ES 2089232T3 ES 91917090 T ES91917090 T ES 91917090T ES 91917090 T ES91917090 T ES 91917090T ES 2089232 T3 ES2089232 T3 ES 2089232T3
- Authority
- ES
- Spain
- Prior art keywords
- class
- epsps
- genes
- glyphosate
- tolerant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
- C12N9/1092—3-Phosphoshikimate 1-carboxyvinyltransferase (2.5.1.19), i.e. 5-enolpyruvylshikimate-3-phosphate synthase
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03H—IMPEDANCE NETWORKS, e.g. RESONANT CIRCUITS; RESONATORS
- H03H3/00—Apparatus or processes specially adapted for the manufacture of impedance networks, resonating circuits, resonators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
- C12N15/8275—Glyphosate
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Waveguide Connection Structure (AREA)
Abstract
SE PRESENTAN ENZIMAS DE LA CLASE II EPSPS QUE CODIFICAN GENES. LOS GENES SON UTILES EN LA PRODUCCION DE BACTERIAS Y PLANTAS TRANSFORMADAS QUE SON TOLERANTES A LOS HERBICIDAS DE GLICOSATO. LOS GENES DE LA CLASE II EPSPS COMPARTEN UNA PEQUEÑA HOMOLOGIA CON LOS GENES YA CONOCIDOS DE LA CLASE I EPSPS, Y NO SE HIBRIDIZAN CON SONDAS DE LA CLASE I EPSPS. LAS ENZIMAS DE LA CLASE II EPSPS SE CARACTERIZAN POR SER MAS CINETICAMENTE EFICIENTES QUE LA CLASE I EPSPS EN LA PRESENCIA DE GLIFOSATO. TAMBIEN SE PRESENTAN PLANTAS TRANSFORMADAS POR LA CLASE II EPSPS ASI COMO UN METODO PARA CONTROLAR DE FORMA SELECTIVA LAS MALAS HIERBAS EN COSECHAS AGRICOLAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US576537 | 1984-02-03 | ||
| US57653790A | 1990-08-31 | 1990-08-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2089232T3 true ES2089232T3 (es) | 1996-10-01 |
| ES2089232T5 ES2089232T5 (es) | 2007-03-16 |
Family
ID=24304844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91917090T Expired - Lifetime ES2089232T5 (es) | 1990-08-31 | 1991-08-28 | 5-enolpiruvilsiquimato-3-fosfato sintasas tolerantes del glifosato. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0546090B2 (es) |
| JP (2) | JP3173785B2 (es) |
| KR (1) | KR920005467A (es) |
| AT (1) | ATE139566T1 (es) |
| AU (1) | AU655945B2 (es) |
| CA (1) | CA2088661C (es) |
| DE (1) | DE69120419T3 (es) |
| DK (1) | DK0546090T4 (es) |
| ES (1) | ES2089232T5 (es) |
| GR (1) | GR3021058T3 (es) |
| RU (1) | RU2146290C1 (es) |
| TW (1) | TW232078B (es) |
| UA (1) | UA32548C2 (es) |
| WO (1) | WO1992004449A1 (es) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7705215B1 (en) * | 1990-04-17 | 2010-04-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5633435A (en) | 1990-08-31 | 1997-05-27 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases |
| GB9515941D0 (en) | 1995-08-03 | 1995-10-04 | Zeneca Ltd | DNA constructs |
| US5928995A (en) * | 1995-05-05 | 1999-07-27 | E. I. Du Pont De Nemours And Company | Herbicidal mixtures |
| PL323587A1 (en) | 1995-05-26 | 1998-04-14 | Zeneca Ltd | Gene changing-over system including edisone receptor |
| US5773696A (en) | 1996-03-29 | 1998-06-30 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
| AU712463B2 (en) * | 1996-03-29 | 1999-11-04 | Monsanto Europe S.A. | New use of N-(phosphonomethyl)glycine and derivatives thereof |
| US6610828B1 (en) | 1996-05-24 | 2003-08-26 | Syngenta Limited | Heliothis ecdysone receptor |
| FR2751347B1 (fr) | 1996-07-16 | 2001-12-07 | Rhone Poulenc Agrochimie | Gene chimere a plusieurs genes de tolerance herbicide, cellule vegetale et plante tolerantes a plusieurs herbicides |
| WO1998020144A2 (en) * | 1996-11-07 | 1998-05-14 | Zeneca Limited | Herbicide resistant plants |
| US6121436A (en) | 1996-12-13 | 2000-09-19 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
| AU748740B2 (en) | 1997-03-25 | 2002-06-13 | Basf Aktiengesellschaft | Expression of herbicide-binding polypeptides in plants to produce herbicide tolerance |
| AR012335A1 (es) | 1997-04-03 | 2000-10-18 | Dekalb Genetics Corp | Planta de maiz transgenica fertil y metodo para prepararla, dichas plantas endogamica y cruzada resistentes al glifosato, metodos para cultivar eincrementar el rendimiento de maiz, producir forraje, alimento para seres humanos, almidon, y criar plantas. |
| US6040497A (en) * | 1997-04-03 | 2000-03-21 | Dekalb Genetics Corporation | Glyphosate resistant maize lines |
| ATE268821T1 (de) | 1997-10-07 | 2004-06-15 | Embrapa Pesquisa Agropecuaria | Herstellung von transgenen leguminosen die exogene sna enthalten |
| FR2772787B1 (fr) | 1997-12-24 | 2001-12-07 | Rhone Poulenc Agrochimie | Promoteur h3c4 de mais associe au premier intron de l'actine de riz, gene chimere le comprenant et plante transformee |
| US6303848B1 (en) * | 1998-01-16 | 2001-10-16 | Large Scale Biology Corporation | Method for conferring herbicide, pest, or disease resistance in plant hosts |
| AR016185A1 (es) * | 1998-03-09 | 2001-06-20 | Monsanto Technology Llc | Metodo para producir plantas con esterilidad masculina; dichas plantas; celulas vegetales que contienen en su genoma una primera molecula de adn, metodopara producir semillas hibridas, dichas semillas y las plantas logradas de estas, y plantas transgenicas y semillas con las celulas vegetales corres |
| US5914451A (en) * | 1998-04-06 | 1999-06-22 | Monsanto Company | Efficiency soybean transformation protocol |
| US6906245B1 (en) | 1998-04-30 | 2005-06-14 | Sumitomo Chemical Company, Limited | Method for producing transgenic plants resistant to weed control compounds which disrupt the porphyrin pathways of plants |
| US6066786A (en) * | 1998-06-17 | 2000-05-23 | Pure Seed Testing, Inc. | Glyphosate tolerant fescue grasses |
| US6271444B1 (en) * | 1998-07-10 | 2001-08-07 | Calgene Llc | Enhancer elements for increased translation in plant plastids |
| WO2000003022A2 (en) * | 1998-07-10 | 2000-01-20 | Calgene Llc | Expression of herbicide tolerance genes in plant plastids |
| US6492578B1 (en) | 1998-07-10 | 2002-12-10 | Calgene Llc | Expression of herbicide tolerance genes in plant plastids |
| US8421158B2 (en) | 1998-12-21 | 2013-04-16 | Megica Corporation | Chip structure with a passive device and method for forming the same |
| US8178435B2 (en) | 1998-12-21 | 2012-05-15 | Megica Corporation | High performance system-on-chip inductor using post passivation process |
| RU2235778C2 (ru) * | 1999-04-29 | 2004-09-10 | Синджента Лимитед | Выделенный полинуклеотид, способный придавать растению устойчивость или толерантность к глифосатному гербициду, вектор, способ получения растений, толерантных или устойчивых к глифосатному гербициду, способ регенерации трансформированного растения и способ селективной борьбы с сорняками |
| CN100425701C (zh) | 1999-12-16 | 2008-10-15 | 孟山都技术有限公司 | 新型植物表达构建物 |
| KR100381930B1 (ko) * | 2000-03-16 | 2003-04-26 | (주)바이오니아 | 유전자 변형 농산물 검출방법 및 검출용 프라이머 |
| US6372966B1 (en) | 2000-06-07 | 2002-04-16 | Pure Seed Testing Inc. | Kentucky bluegrass variety known as ‘Brilliant’ |
| US6407319B1 (en) | 2000-06-07 | 2002-06-18 | Pure Seed Testing, Inc. | Kentucky bluegrass variety known as ‘North Star’ |
| AU1536302A (en) | 2000-10-25 | 2002-05-06 | Monsanto Technology Llc | Cotton event pv-ghgt07(1445) and compositions and methods for detection thereof |
| EP1337669A2 (en) * | 2000-11-30 | 2003-08-27 | Ses Europe N.V./S.A. | Glyphosate resistant transgenic sugar beet characterised by a specific transgene insertion (t227-1), methods and primers for the detection of said insertion |
| US6423887B1 (en) | 2001-03-14 | 2002-07-23 | Pure Seed Testing, Inc. | Glyphosate tolerant fescue grass variety |
| US7977046B2 (en) | 2002-05-10 | 2011-07-12 | Monsanto Technology Llc | Method of selecting DNA constructs for herbicide tolerance in plants |
| ATE497538T1 (de) | 2002-02-26 | 2011-02-15 | Syngenta Ltd | Verfahren zur selektiven herstellung männlich- oder weiblich-steriler pflanzen |
| AU2003247962B2 (en) | 2002-07-18 | 2008-06-12 | Monsanto Technology Llc | Methods for using artificial polynucleotides and compositions thereof to reduce transgene silencing |
| US7365186B2 (en) | 2002-11-22 | 2008-04-29 | Arborgen, Llc | Vascular-preferred promoter sequences and uses thereof |
| FR2848570B1 (fr) | 2002-12-12 | 2005-04-01 | Bayer Cropscience Sa | Cassette d'expression codant pour une 5-enol pyruvylshikimate-3-phosphate synthase (epsps) et plantes tolerantes aux herbicides la contenant |
| BR122015019398B1 (pt) | 2003-01-31 | 2019-10-01 | Monsanto Technology Llc | Métodos para produzir planta de alfafa tolerante a glifosato tendo evento transgênico j-163 e para produzir feno de alfafa |
| WO2005001051A2 (en) | 2003-06-06 | 2005-01-06 | Arborgen Llc. | Compositions and methods for regulating polysaccharides of a plant cell |
| US8153410B2 (en) | 2003-07-07 | 2012-04-10 | Fox Chase Cancer Center | Alternate morpheein forms of allosteric proteins as a target for the development of bioactive molecules |
| US20060162014A1 (en) | 2003-07-07 | 2006-07-20 | Jaffe Eileen K | Alternate morpheeins of allosteric proteins as a target for the development of bioactive molecules |
| CA2540348C (en) | 2003-09-29 | 2016-04-26 | Monsanto Technology Llc | Methods 0f enhancing stress tolerance in plants and compositions thereof |
| UA85690C2 (ru) | 2003-11-07 | 2009-02-25 | Басф Акциенгезелльшафт | Смесь для применения в сельском хозяйстве, содержащая стробилурин и модулятор этилена, способ обработки и борьбы с инфекциями в бобовых культурах |
| HRP20150814T1 (xx) | 2003-12-15 | 2015-08-28 | Monsanto Technology, Llc | Biljka kukuruza mon88017 te sastavi i postupci za njezino otkrivanje |
| US7799906B1 (en) | 2004-09-22 | 2010-09-21 | Arborgen, Llc | Compositions and methods for modulating lignin of a plant |
| US7453025B2 (en) | 2004-09-22 | 2008-11-18 | Arborgen, Llc | Reproductive ablation constructs |
| AP2693A (en) * | 2005-05-27 | 2013-07-16 | Monsanto Technology Llc | Soybean event MON89788 and methods for detection thereof |
| CA2616535A1 (en) * | 2005-07-29 | 2007-02-08 | Monsanto Technology Llc | Development of novel germplasm using segregates from transgenic crosses |
| KR100674860B1 (ko) * | 2005-08-10 | 2007-01-29 | 삼성전기주식회사 | 저온 소결용 글라스 프릿트 |
| EA023885B1 (ru) | 2005-10-13 | 2016-07-29 | МОНСАНТО ТЕКНОЛОДЖИ, ЭлЭлСи | Конструкция рекомбинантной днк для индуцирования стерильности в трансгенном растении, стерильные трансгенные растения и способы получения гибридных семян |
| AR057205A1 (es) * | 2005-12-01 | 2007-11-21 | Athenix Corp | Genes grg23 y grg51 que confieren resistencia a herbicidas |
| CA2639900C (en) | 2006-01-23 | 2014-08-26 | Board Of Trustees Of Michigan State University | Methods for breeding glyphosate resistant plants and compositions thereof |
| WO2008002962A2 (en) * | 2006-06-27 | 2008-01-03 | Athenix Corporation | Grg32: a novel epsp synthase gene conferring herbicide resistance |
| NZ574568A (en) * | 2006-08-11 | 2011-04-29 | Monsanto Technology Llc | Production of high tryptophan maize by chloroplast targeted expression of anthranilate synthase |
| US8536406B2 (en) | 2008-04-28 | 2013-09-17 | Michigan Technological University | COMT1 gene fiber-specific promoter elements from poplar |
| AR074941A1 (es) | 2009-01-07 | 2011-02-23 | Bayer Cropscience Sa | Plantas transplastomicas exentas de marcador de seleccion |
| EP3213635A1 (en) | 2009-06-25 | 2017-09-06 | Basf Se | Use of agrochemical mixtures for increasing the health of a plant |
| IN2012DN00427A (es) | 2009-07-01 | 2015-05-15 | Bayer Bioscience Nv | |
| WO2011132778A1 (ja) | 2010-04-23 | 2011-10-27 | 日立化成工業株式会社 | p型拡散層形成組成物、p型拡散層の製造方法、及び太陽電池素子の製造方法 |
| CN103037696A (zh) | 2010-05-31 | 2013-04-10 | 巴斯夫欧洲公司 | 增加植物健康的方法 |
| CN103635483B (zh) | 2011-07-01 | 2016-11-09 | 孟山都技术公司 | 用于选择性调控蛋白质表达的方法和组合物 |
| MX2014001072A (es) | 2011-07-28 | 2014-09-25 | Genective | Evento vco-ø1981-5 de maiz tolerante a glifosato y kit y metodo para detectar el mismo. |
| KR102047336B1 (ko) * | 2012-02-01 | 2019-11-22 | 다우 아그로사이언시즈 엘엘씨 | 신규한 클래스의 글리포세이트 저항성 유전자 |
| AU2013205557B2 (en) * | 2012-04-17 | 2016-04-21 | Corteva Agriscience Llc | Synthetic brassica-derived chloroplast transit peptides |
| BR112015015055A2 (pt) | 2012-12-21 | 2017-10-03 | Pioneer Hi Bred Int | Método para desintoxicar um herbicida análogo de auxina, método para controlar pelo menos uma erva em uma área de cultivo, método para testar uma resposta de planta a um ou mais compostos |
| BR112015023272A2 (pt) | 2013-03-14 | 2017-07-18 | Pioneer Hi Bred Int | célula vegetal, planta, explante vegetal, semente transgênica, método para produzir uma célula vegetal tendo um polinucleotídeo heterólogo que codifica um polipeptídeo tendo atividade de dicamba descarboxilase, método para controlar plantas daninhas em um campo contendo uma cultura e método para controlar plantas daninhas em um campo contendo uma cultura |
| AU2014236162A1 (en) | 2013-03-14 | 2015-09-17 | Arzeda Corp. | Compositions having dicamba decarboxylase activity and methods of use |
| CN114965840B (zh) * | 2021-02-24 | 2024-06-14 | 公安部物证鉴定中心 | 一种生物体液中草甘膦、草铵膦及代谢物的检测方法 |
| CN116411021B (zh) * | 2023-06-07 | 2023-08-15 | 隆平生物技术(海南)有限公司 | 一种番茄草甘膦筛选体系的转化方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1170991A1 (ru) * | 1982-06-16 | 1985-08-07 | Всесоюзный Ордена Ленина И Ордена Трудового Красного Знамени Селекционно-Генетический Институт | Способ селекции пшеницы,устойчивой к неблагопри тным факторам |
| US4535060A (en) * | 1983-01-05 | 1985-08-13 | Calgene, Inc. | Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use |
| SU1165314A1 (ru) * | 1983-03-28 | 1985-07-07 | Институт экспериментальной ботаники им.В.Ф.Купревича | Способ отбора устойчивых к 2,4- @ форм чмен |
| CA1313830C (en) * | 1985-08-07 | 1993-02-23 | Dilip Maganlal Shah | Glyphosate-resistant plants |
| US4971908A (en) * | 1987-05-26 | 1990-11-20 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase |
| US5310667A (en) * | 1989-07-17 | 1994-05-10 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases |
| ES2150900T3 (es) * | 1989-10-31 | 2000-12-16 | Monsanto Co | Promotor para plantas transgenicas. |
-
1991
- 1991-08-28 DE DE69120419T patent/DE69120419T3/de not_active Expired - Lifetime
- 1991-08-28 RU RU93038869A patent/RU2146290C1/ru active
- 1991-08-28 JP JP51752091A patent/JP3173785B2/ja not_active Expired - Lifetime
- 1991-08-28 ES ES91917090T patent/ES2089232T5/es not_active Expired - Lifetime
- 1991-08-28 WO PCT/US1991/006148 patent/WO1992004449A1/en not_active Ceased
- 1991-08-28 AU AU86578/91A patent/AU655945B2/en not_active Expired
- 1991-08-28 UA UA94041118A patent/UA32548C2/uk unknown
- 1991-08-28 AT AT91917090T patent/ATE139566T1/de not_active IP Right Cessation
- 1991-08-28 DK DK91917090T patent/DK0546090T4/da active
- 1991-08-28 CA CA002088661A patent/CA2088661C/en not_active Expired - Lifetime
- 1991-08-28 EP EP91917090A patent/EP0546090B2/en not_active Expired - Lifetime
- 1991-08-30 KR KR1019910015106A patent/KR920005467A/ko not_active Withdrawn
- 1991-11-29 TW TW080109394A patent/TW232078B/zh active
-
1996
- 1996-09-18 GR GR960402426T patent/GR3021058T3/el unknown
-
2000
- 2000-11-13 JP JP2000345384A patent/JP2001197841A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE139566T1 (de) | 1996-07-15 |
| WO1992004449A1 (en) | 1992-03-19 |
| UA32548C2 (uk) | 2001-02-15 |
| GR3021058T3 (en) | 1996-12-31 |
| EP0546090B2 (en) | 2006-07-19 |
| DE69120419T3 (de) | 2007-02-15 |
| DE69120419T2 (de) | 1997-01-09 |
| AU655945B2 (en) | 1995-01-19 |
| AU8657891A (en) | 1992-03-30 |
| JP2001197841A (ja) | 2001-07-24 |
| JP3173785B2 (ja) | 2001-06-04 |
| CA2088661C (en) | 2001-12-18 |
| ES2089232T5 (es) | 2007-03-16 |
| JPH06500472A (ja) | 1994-01-20 |
| DK0546090T3 (da) | 1996-07-29 |
| EP0546090A1 (en) | 1993-06-16 |
| RU2146290C1 (ru) | 2000-03-10 |
| KR920005467A (ko) | 1992-03-28 |
| EP0546090B1 (en) | 1996-06-19 |
| CA2088661A1 (en) | 1992-03-01 |
| TW232078B (es) | 1994-10-11 |
| DK0546090T4 (da) | 2006-11-20 |
| DE69120419D1 (de) | 1996-07-25 |
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