ES2090411T3 - Procedimiento para la preparacion enzimatica de derivados de cefalosporano. - Google Patents

Procedimiento para la preparacion enzimatica de derivados de cefalosporano.

Info

Publication number
ES2090411T3
ES2090411T3 ES92109410T ES92109410T ES2090411T3 ES 2090411 T3 ES2090411 T3 ES 2090411T3 ES 92109410 T ES92109410 T ES 92109410T ES 92109410 T ES92109410 T ES 92109410T ES 2090411 T3 ES2090411 T3 ES 2090411T3
Authority
ES
Spain
Prior art keywords
cephalosporan
derivatives
procedure
enzymatic preparation
cooh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92109410T
Other languages
English (en)
Inventor
Ezio Angelo Battistel
Pietro Cesti
Giuliana Franzosi
Der Goes Vilhelmus Van
Silvana Bonicelli
Mirella Pilone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ministero dell Universita e della Ricerca Scientifica e Tecnologica (MURST)
Original Assignee
Ministero dell Universita e della Ricerca Scientifica e Tecnologica (MURST)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ministero dell Universita e della Ricerca Scientifica e Tecnologica (MURST) filed Critical Ministero dell Universita e della Ricerca Scientifica e Tecnologica (MURST)
Application granted granted Critical
Publication of ES2090411T3 publication Critical patent/ES2090411T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024D-Amino acid oxidase (1.4.3.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungi isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06Cephalosporin C; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE DESCRIBE UN PROCESO PARA LA PRODUCCION ENZIMATICA DE DERIVADOS DE CEFALOSPORANO, O DE SUS SALES, QUE TIENEN LA FORMULA (I): EN DONDE R REPRESENTA UN GRUPO -CO-COOH O -COOH Y R'' ES H, OH O O-CO-R", SIENDO R" UN GRUPO ALKILO C1-C4, INCLUIDA LA DESAMINACION OXIDATIVA DE LOS COMPUESTOS, O DE SUS SALES, QUE TIENEN LA FORMULA (II): ANTE LA PRESENCIA DE UN MICROORGANISMO DEL TIPO RHODOTORULA O UNA OXIDASA D-AMINOACIDA DERIVADA DEL MISMO, CON FORMA LIBRE O INMOVILIZADA.
ES92109410T 1991-06-03 1992-06-03 Procedimiento para la preparacion enzimatica de derivados de cefalosporano. Expired - Lifetime ES2090411T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI911509A IT1247964B (it) 1991-06-03 1991-06-03 Processo per la preparazione enzimatica di derivati cefalosporanici

Publications (1)

Publication Number Publication Date
ES2090411T3 true ES2090411T3 (es) 1996-10-16

Family

ID=11360034

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92109410T Expired - Lifetime ES2090411T3 (es) 1991-06-03 1992-06-03 Procedimiento para la preparacion enzimatica de derivados de cefalosporano.

Country Status (9)

Country Link
US (1) US5296358A (es)
EP (1) EP0517200B1 (es)
JP (1) JP3131024B2 (es)
AT (1) ATE141333T1 (es)
CA (1) CA2070083A1 (es)
DE (1) DE69212713T2 (es)
DK (1) DK0517200T3 (es)
ES (1) ES2090411T3 (es)
IT (1) IT1247964B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5597704A (en) * 1995-05-01 1997-01-28 Food Industry Research And Development Institute Bioconversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid
ES2109194B1 (es) * 1996-04-22 1998-07-16 Antibioticos Sa Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes.
JPH10295392A (ja) * 1997-04-22 1998-11-10 Kanegafuchi Chem Ind Co Ltd L−アルリジンアセタールの製造方法
US5877013A (en) * 1997-07-31 1999-03-02 Food Industry Research And Development Institute Rhodosporidium D-amino acid oxidase
DE19937187A1 (de) * 1999-08-06 2001-03-01 Qiagen Gmbh Automatisierte Proteinreinigung im Multiwellformat durch Vakuumfiltration
KR20040014498A (ko) * 2001-04-19 2004-02-14 바이오퍼마 무르시아, 에스.에이. 세팔로스포린 유도체의 제조 방법
KR100512774B1 (ko) * 2001-10-06 2005-09-07 종근당바이오 주식회사 7-아미노세팔로스포란산의 제조를 위한 세팔로스포린c배양액의 전처리방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
GB1272769A (en) * 1968-08-02 1972-05-03 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
GB1385685A (en) * 1971-04-21 1975-02-26 Glaxo Lab Ltd Cephalosporin derivatives
GB1474519A (es) * 1973-05-14 1977-05-25
DE4028119C1 (es) * 1990-09-05 1991-12-05 Hoechst Ag, 6230 Frankfurt, De

Also Published As

Publication number Publication date
ITMI911509A0 (it) 1991-06-03
DE69212713D1 (de) 1996-09-19
ATE141333T1 (de) 1996-08-15
ITMI911509A1 (it) 1992-12-03
CA2070083A1 (en) 1992-12-04
DK0517200T3 (da) 1996-09-02
IT1247964B (it) 1995-01-05
US5296358A (en) 1994-03-22
EP0517200B1 (en) 1996-08-14
EP0517200A2 (en) 1992-12-09
EP0517200A3 (en) 1993-03-03
JP3131024B2 (ja) 2001-01-31
JPH05244991A (ja) 1993-09-24
DE69212713T2 (de) 1997-03-06

Similar Documents

Publication Publication Date Title
ES2033423T3 (es) Procedimientos para preparar derivados de 2-fenilpurinona.
ES8603883A1 (es) Procedimiento para preparar nuevos 2-fenil-imidazoles
ES8306373A1 (es) "procedimiento para la preparacion de 9-(2-(3-indolil)-etil)-1-oxa-4,9-diazaspiro (5.5) undecan-3-onas".
ES2051843T3 (es) Un proceso para la preparacion de un derivado del acido benzoilaminofenoxibutanico.
ES2076398T3 (es) Procedimiento para la preparacion de sales de la l-ornitina.
ES8304974A1 (es) "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina".
ES8203964A1 (es) Un procedimiento para la preparacion de compuestos de polie-ter antibioticos
ES8306719A1 (es) Un procedimiento para la preparacion de derivados de 2-c2 bencil-3-mercaptopropionilamino-1-alcanoles.
ES546935A0 (es) Procedimiento para la preparacion de derivados anilinicos para la deteccion de sistemas redox
AU546256B2 (en) Bispidine derivatives with antiarrhythmic activity
ES2090411T3 (es) Procedimiento para la preparacion enzimatica de derivados de cefalosporano.
ES8801377A1 (es) Procedimiento para la produccion de d-l-amino acidos
ES8707250A1 (es) Procedimiento para preparar acidos fosfonicos y derivados de los mismos
PH24769A (en) 2,6-dichloro-5-fluoro-pyridine-3-carboxylic acid derivatives
ES8706692A1 (es) Un metodo para preparar nuevos derivados de cefem
ES2052522T3 (es) Derivados de pirimidina, su preparacion y medicamentos que los contienen.
ATE22069T1 (de) Verfahren zur herstellung von 2-amino-3,5dibrombenzylaminen.
ES2001856A6 (es) Una composicion acuosa basica de isotiazolonas n-insustituidas
FI871637A0 (fi) Foerfarande foer framstaellning av 1,5-benzotiazepinderivat.
ES2038194T3 (es) Procedimiento para la obtencion de derivados de la benzhidriloxietil-piperidina.
MX169097B (es) Procedimiento para la obtencion de colorantes de hidrazona cationicos
ES2064923T3 (es) Metodo para estabilizar una solucion acuosa acida de peroxido de hidrogeno que contiene cobre.
ES2094278T3 (es) Procedimiento para la preparacion enzimatica de acidos 7-amino-cefalosporanicos.
ES8505357A1 (es) Un procedimiento para la preparacion de derivados de carboxi-tiazolo (3,2-a) pirimidina nuevos
ES8205017A1 (es) Procedimiento para la preparacion de carbamilderivados de &-hidroxiacidos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 517200

Country of ref document: ES

FG2A Definitive protection

Ref document number: 517200

Country of ref document: ES