ES2093103T3 - Interleuquina-4 cristalina. - Google Patents

Interleuquina-4 cristalina.

Info

Publication number
ES2093103T3
ES2093103T3 ES91910825T ES91910825T ES2093103T3 ES 2093103 T3 ES2093103 T3 ES 2093103T3 ES 91910825 T ES91910825 T ES 91910825T ES 91910825 T ES91910825 T ES 91910825T ES 2093103 T3 ES2093103 T3 ES 2093103T3
Authority
ES
Spain
Prior art keywords
interleuquina
cristalina
rhu
sulphate
citrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91910825T
Other languages
English (en)
Inventor
Gerald Hammond
Hung V Le
T L Nagabhushan
Paul Reichert
Paul P Trotta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2093103T3 publication Critical patent/ES2093103T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE DESCRIBE UN PROCESO PARA LA CRISTALIZACION DE UNA INTERLEUKINA-4 HUMANA RECOMBINANTE (RHU IL-4) A PARTIR DE UNA SOLUCION QUE CONTIENE UNA SAL DE CITRATO O DE SULFATO. LA FORMA CRISTALINA ES ADECUADA PARA UNA DIFRACCION DE RAYOS X Y PRESENTA UNA AMPLIA GAMA DE APLICACIONES EN VARIOS PROCESOS FARMACEUTICOS INCLUIDOS LA PURIFICACION, FORMULACION Y FABRICACION.
ES91910825T 1990-06-15 1991-06-13 Interleuquina-4 cristalina. Expired - Lifetime ES2093103T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53863690A 1990-06-15 1990-06-15

Publications (1)

Publication Number Publication Date
ES2093103T3 true ES2093103T3 (es) 1996-12-16

Family

ID=24147762

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91910825T Expired - Lifetime ES2093103T3 (es) 1990-06-15 1991-06-13 Interleuquina-4 cristalina.

Country Status (18)

Country Link
EP (1) EP0597850B1 (es)
JP (1) JP2509775B2 (es)
CN (2) CN1033034C (es)
AT (1) ATE143672T1 (es)
CA (1) CA2085377A1 (es)
DE (1) DE69122517T2 (es)
ES (1) ES2093103T3 (es)
FI (1) FI925687L (es)
HU (1) HU209313B (es)
IE (1) IE62372B1 (es)
IL (1) IL98484A0 (es)
MY (1) MY107577A (es)
NZ (1) NZ238530A (es)
OA (1) OA09722A (es)
PL (1) PL166951B1 (es)
PT (1) PT97985A (es)
WO (1) WO1991019742A1 (es)
ZA (1) ZA914539B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302278D0 (sv) * 1992-10-28 1993-07-02 Kabi Pharmacia Ab Growth hormone
HU225496B1 (en) * 1993-04-07 2007-01-29 Scios Inc Pharmaceutical compositions of prolonged delivery, containing peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62167798A (ja) * 1986-01-20 1987-07-24 Ajinomoto Co Inc インタ−ロイキン２結晶及びその製造法

Also Published As

Publication number Publication date
WO1991019742A1 (en) 1991-12-26
MY107577A (en) 1996-04-30
IL98484A0 (en) 1992-07-15
ZA914539B (en) 1992-03-25
PL166951B1 (pl) 1995-07-31
DE69122517D1 (de) 1996-11-07
DE69122517T2 (de) 1997-02-13
JP2509775B2 (ja) 1996-06-26
CA2085377A1 (en) 1991-12-16
IE62372B1 (en) 1995-01-25
PT97985A (pt) 1992-03-31
ATE143672T1 (de) 1996-10-15
EP0597850B1 (en) 1996-10-02
AU8094991A (en) 1992-01-07
NZ238530A (en) 1993-12-23
AU642511B2 (en) 1993-10-21
FI925687A0 (fi) 1992-12-15
JPH05507707A (ja) 1993-11-04
FI925687A7 (fi) 1992-12-15
CN1033034C (zh) 1996-10-16
OA09722A (en) 1993-08-30
IE912009A1 (en) 1991-12-18
CN1057268A (zh) 1991-12-25
EP0597850A1 (en) 1994-05-25
FI925687L (fi) 1992-12-15
HU209313B (en) 1994-04-28
HU9203959D0 (en) 1993-03-29
HUT63439A (en) 1993-08-30
CN1119121A (zh) 1996-03-27

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