ES2097733T3 - Derivados de la manobiosa. - Google Patents

Derivados de la manobiosa.

Info

Publication number
ES2097733T3
ES2097733T3 ES88105313T ES88105313T ES2097733T3 ES 2097733 T3 ES2097733 T3 ES 2097733T3 ES 88105313 T ES88105313 T ES 88105313T ES 88105313 T ES88105313 T ES 88105313T ES 2097733 T3 ES2097733 T3 ES 2097733T3
Authority
ES
Spain
Prior art keywords
groups
chem
represented
nhr6
manobious
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88105313T
Other languages
English (en)
Inventor
Hideki Miyaji
Shusaburo Hokukoku
Munehiro Tomikawa
Sadao Hirota
Hiroshi Kikuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Meito Sangyo KK
Original Assignee
Daiichi Pharmaceutical Co Ltd
Meito Sangyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd, Meito Sangyo KK filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2097733T3 publication Critical patent/ES2097733T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE MANOBIOSA REPRESENTADOS POR LA FORMULA GENERAL (I), DONDE GRUPOS DE R1 A R6 REPRESENTAN -OH, -OR6, -NHR6, (R6 REPRESENTA UN GRUPO ACILO) O UN GRUPO REPRESENTADO POR LA FORMULA SIGUIENTE (A), (B), (C), (D) O (E) SIEMPRE QUE UNO DE R1 A R5 REPRESENTE -OR6 O -NHR6, UNO DE LOS OTROS 4 GRUPOS DE R1 A R5 REPRESENTA UNO DE LOS GRUPOS REPRESENTADOS POR LAS FORMULAS (A) A (E), Y LOS RESTANTES 3 GRUPOS DE R1 A R5 REPRESENTEN -OH. ESTOS COMPUESTOS DAN LIPOSOMAS CON AFINIDAD ESPECIFICA PARA CELULAS 12 UPFFLER DE HIGADO, Y PUEDEN PRODUCIRSE INDUSTRIALMENTE.
ES88105313T 1987-04-03 1988-03-31 Derivados de la manobiosa. Expired - Lifetime ES2097733T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8273687 1987-04-03

Publications (1)

Publication Number Publication Date
ES2097733T3 true ES2097733T3 (es) 1997-04-16

Family

ID=13782702

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88105313T Expired - Lifetime ES2097733T3 (es) 1987-04-03 1988-03-31 Derivados de la manobiosa.

Country Status (10)

Country Link
US (1) US4983725A (es)
EP (1) EP0285178B1 (es)
KR (1) KR950000780B1 (es)
AT (1) ATE148887T1 (es)
AU (1) AU608820B2 (es)
CA (1) CA1310962C (es)
DE (1) DE3855791T2 (es)
ES (1) ES2097733T3 (es)
GR (1) GR3023077T3 (es)
PH (1) PH26549A (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645741B1 (fr) * 1989-03-20 1995-06-23 Dior Christian Parfums Procede pour fixer un produit sur la membrane d'un keratinocyte au moyen d'une liaison ligand-recepteur, procede de preparation d'un tel produit, produit obtenu, composition cosmetique ou pharmaceutique le contenant et son procede de preparation
US5362480A (en) * 1991-12-31 1994-11-08 Lever Brothers Company, Division Of Conopco, Inc. Oral hygiene compositions containing amino sugars as antiplaque agents
US5310542A (en) * 1991-12-31 1994-05-10 Lever Brothers Company, Division Of Conopco, Inc. Oral hygiene compositions containing antiplaque agents
US5409902A (en) * 1991-12-31 1995-04-25 Lever Brothers Company Oral hygiene compositions containing glyceroglycolipids as antiplaque compounds
JP2828391B2 (ja) * 1993-10-29 1998-11-25 東燃株式会社 オリゴ糖を表面に有するリポソーム
JP3664401B2 (ja) * 2003-01-22 2005-06-29 独立行政法人科学技術振興機構 Ｎ−グリコシド型糖脂質及びこれから成る中空繊維状有機ナノチューブ
WO2009006620A1 (en) 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses
AU2008272854B2 (en) * 2007-07-03 2014-03-13 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-N-acetylase and methods for using the same
WO2009006613A1 (en) 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
RU2481351C2 (ru) * 2008-05-08 2013-05-10 Индус Биотек Прайвет Лимитед Композиции, содержащие галактоманнан, и способ их получения

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2504983A (en) * 1948-08-31 1950-04-25 Us Commerce Process for making crystalline 1-aminomannuronic amide
US2802819A (en) * 1953-07-24 1957-08-13 Ciba Pharm Prod Inc Acylated products
US3142620A (en) * 1961-03-23 1964-07-28 Ciba Geigy Corp Immunizing composition containing mesoinosito-tri-alpha-d-mannoside
JPS5772997A (en) * 1980-10-23 1982-05-07 Rikagaku Kenkyusho Novel oligomannoside and its preparation
JPS5772996A (en) * 1980-10-23 1982-05-07 Rikagaku Kenkyusho Novel oligomannoside and its preparation
JPS57146797A (en) * 1981-03-09 1982-09-10 Rikagaku Kenkyusho Novel oligomannoside and its preparation
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
DE3410238A1 (de) * 1984-03-21 1985-10-03 Bayer Ag, 5090 Leverkusen Glycolipid-aehnliche substanzen in liposomenform
JPS61112021A (ja) * 1984-11-06 1986-05-30 Dai Ichi Seiyaku Co Ltd 脂質膜構造体
JPH0699462B2 (ja) * 1985-10-31 1994-12-07 名糖産業株式会社 ラクト−ス高級脂肪酸誘導体

Also Published As

Publication number Publication date
CA1310962C (en) 1992-12-01
EP0285178A2 (en) 1988-10-05
AU1406188A (en) 1988-10-06
EP0285178B1 (en) 1997-02-12
ATE148887T1 (de) 1997-02-15
AU608820B2 (en) 1991-04-18
DE3855791D1 (de) 1997-03-27
EP0285178A3 (en) 1991-08-28
US4983725A (en) 1991-01-08
KR950000780B1 (ko) 1995-02-02
DE3855791T2 (de) 1997-06-05
PH26549A (en) 1992-08-19
KR880012622A (ko) 1988-11-28
GR3023077T3 (en) 1997-07-30

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