ES2100285T3 - Analisis de muestras utilizando electroforesis capilar. - Google Patents
Analisis de muestras utilizando electroforesis capilar.Info
- Publication number
- ES2100285T3 ES2100285T3 ES92303985T ES92303985T ES2100285T3 ES 2100285 T3 ES2100285 T3 ES 2100285T3 ES 92303985 T ES92303985 T ES 92303985T ES 92303985 T ES92303985 T ES 92303985T ES 2100285 T3 ES2100285 T3 ES 2100285T3
- Authority
- ES
- Spain
- Prior art keywords
- shock absorber
- sample analysis
- capillary electrophoresis
- modifier
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004458 analytical method Methods 0.000 title abstract 2
- 238000005251 capillar electrophoresis Methods 0.000 title 1
- 239000006096 absorbing agent Substances 0.000 abstract 4
- 230000035939 shock Effects 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000003607 modifier Substances 0.000 abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004327 boric acid Substances 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 238000001962 electrophoresis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Dispersion Chemistry (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Electron Tubes For Measurement (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
SE PRESENTA UN METODO Y UN AMORTIGUADOR ELECTROLITO UTIL EN EL ANALISIS DE MUESTRAS QUE COMPRENDAN GLICOPROTEINAS MEDIANTE LA ELECTROFORESIS DE ZONA CAPILAR. EL AMORTIGUADOR COMPRENDE AL MENOS UN AGENTE CAPAZ DE COMPLEJARSE CON LAS MOLECULAS DE SACAROSA DE LAS GLICOPROTEINAS. EL AMORTIGUADOR COMPRENDE ADEMAS AL MENOS UN MODIFICADOR DEL PH. UNA CONFORMACION DEL AMORTIGUADOR COMPRENDE ACIDO BORICO COMO AGENTE COMPLEJADOR E HIDROXIDO DE SODIO COMO MODIFICADOR DEL PH.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/708,272 US5120413A (en) | 1991-05-31 | 1991-05-31 | Analysis of samples utilzing capillary electrophoresis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2100285T3 true ES2100285T3 (es) | 1997-06-16 |
Family
ID=24845108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92303985T Expired - Lifetime ES2100285T3 (es) | 1991-05-31 | 1992-05-01 | Analisis de muestras utilizando electroforesis capilar. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5120413A (es) |
| EP (1) | EP0518475B1 (es) |
| JP (1) | JPH0760147B2 (es) |
| AT (1) | ATE151533T1 (es) |
| AU (1) | AU662138B2 (es) |
| CA (1) | CA2069053C (es) |
| DE (1) | DE69218832T2 (es) |
| ES (1) | ES2100285T3 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5259939A (en) * | 1991-08-30 | 1993-11-09 | Beckman Instruments, Inc. | Capillary electrophoresis buffer |
| US5228960A (en) * | 1992-07-17 | 1993-07-20 | Beckman Instruments, Inc. | Analysis of samples by capillary electrophoretic immunosubtraction |
| US5348633A (en) * | 1993-01-22 | 1994-09-20 | Northeastern University | Method for quantitating trace amounts of an analyte in a sample by affinity capillary electrophoresis |
| AU669308B2 (en) * | 1993-10-07 | 1996-05-30 | Beckman Instruments, Inc. | Use of capillary electrophoresis for quantitating the concentration of protein components and of the total proteinin fluids |
| US5567282A (en) * | 1994-01-25 | 1996-10-22 | Wang; Hann-Ping | On-capillary electrophoretic immunosubtraction for classification and typing of M-proteins |
| US6783651B1 (en) * | 1994-03-31 | 2004-08-31 | Invitrogen Corporation | System for pH-neutral stable electrophoresis gel |
| US5578180A (en) * | 1994-03-31 | 1996-11-26 | Novel Experimental Technology | System for PH-neutral longlife precast electrophoresis gel |
| EP0704053A1 (en) * | 1994-04-13 | 1996-04-03 | Beckman Instruments, Inc. | Analysis of analytes in biological fluids |
| US5536382A (en) * | 1994-05-23 | 1996-07-16 | Advanced Molecular Systems, Inc. | Capillary electrophoresis assay method useful for the determination of constituents of a clinical sample |
| US5431793A (en) * | 1994-07-29 | 1995-07-11 | Beckman Instruments, Inc. | Quantitative analysis of glycosylated hemoglobin by immunocappillary electrophoresis |
| US5599433A (en) * | 1995-01-17 | 1997-02-04 | Beckman Instruments, Inc. | Capillary electrophoresis of glycosylated proteins |
| US5630924A (en) * | 1995-04-20 | 1997-05-20 | Perseptive Biosystems, Inc. | Compositions, methods and apparatus for ultrafast electroseparation analysis |
| US5753094A (en) * | 1995-09-20 | 1998-05-19 | Beckman Instruments, Inc. | Borate storage buffer and sample diluent |
| US5922184A (en) * | 1997-07-21 | 1999-07-13 | Bio-Rad Laboratories, Inc. | Computer-directed detection of paraproteins |
| US6274017B1 (en) | 1996-12-14 | 2001-08-14 | National University Of Singapore | Buffer for analyzing small inorganic cations by capillary electrophoresis |
| US5939208A (en) * | 1997-11-07 | 1999-08-17 | Biomimetics, Inc. | Method for creation of biomimetic surfaces |
| FR2819889B1 (fr) * | 2001-01-19 | 2003-08-01 | Sebia Sa | Procede d'electrophorese capillaire en solution libre a ph alcalin |
| FR2819888B1 (fr) * | 2001-01-19 | 2003-09-12 | Sebia Sa | Procede de separation de proteines par electrophorese capillaire et compositions de tampon pour electrophorese capillaire |
| US7381317B2 (en) * | 2002-08-12 | 2008-06-03 | Beckman Coulter, Inc. | Methods and compositions for capillary electrophoresis (CE) |
| US20050249882A1 (en) * | 2004-05-04 | 2005-11-10 | Shaorong Liu | Coatings for molecule transport and separations |
| FR2869995B1 (fr) * | 2004-05-10 | 2006-09-22 | Sebia Sa | Procede ameliore de separation de proteines par electrophorese capillaire et compositions de tampon pour electrophorese capillaire |
| US20070014699A1 (en) | 2005-06-23 | 2007-01-18 | Beckman Coulter, Inc, | Methods and apparatus for improving the sensitivity of capillary zone electrophoresis |
| FR2947632B1 (fr) * | 2009-07-01 | 2011-11-11 | Sebia Sa | Analyse et dosage d'hemoglobines glyquees par electrophorese capillaire, compositions tampon et kits pour electrophorese capillaire |
| CN104024849A (zh) | 2011-08-12 | 2014-09-03 | 生命科技公司 | 用于高通量聚糖分析的装置、方法、计算机程序产品和试剂盒 |
| CN111289598A (zh) * | 2020-03-23 | 2020-06-16 | 东莞市东阳光生物药研发有限公司 | 测定重组蛋白电荷异质性的方法 |
-
1991
- 1991-05-31 US US07/708,272 patent/US5120413A/en not_active Expired - Fee Related
-
1992
- 1992-05-01 AT AT92303985T patent/ATE151533T1/de not_active IP Right Cessation
- 1992-05-01 ES ES92303985T patent/ES2100285T3/es not_active Expired - Lifetime
- 1992-05-01 EP EP92303985A patent/EP0518475B1/en not_active Expired - Lifetime
- 1992-05-01 DE DE69218832T patent/DE69218832T2/de not_active Expired - Fee Related
- 1992-05-14 AU AU16287/92A patent/AU662138B2/en not_active Ceased
- 1992-05-20 CA CA002069053A patent/CA2069053C/en not_active Expired - Fee Related
- 1992-06-01 JP JP4163337A patent/JPH0760147B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69218832D1 (de) | 1997-05-15 |
| CA2069053A1 (en) | 1992-12-01 |
| EP0518475B1 (en) | 1997-04-09 |
| AU1628792A (en) | 1992-12-03 |
| AU662138B2 (en) | 1995-08-24 |
| US5120413A (en) | 1992-06-09 |
| ATE151533T1 (de) | 1997-04-15 |
| CA2069053C (en) | 1999-05-18 |
| JPH0760147B2 (ja) | 1995-06-28 |
| DE69218832T2 (de) | 1997-07-17 |
| EP0518475A1 (en) | 1992-12-16 |
| JPH05322846A (ja) | 1993-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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