ES2102435T3 - Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico. - Google Patents

Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico.

Info

Publication number
ES2102435T3
ES2102435T3 ES92117248T ES92117248T ES2102435T3 ES 2102435 T3 ES2102435 T3 ES 2102435T3 ES 92117248 T ES92117248 T ES 92117248T ES 92117248 T ES92117248 T ES 92117248T ES 2102435 T3 ES2102435 T3 ES 2102435T3
Authority
ES
Spain
Prior art keywords
beta
pharmaceutical preparation
preparation containing
containing protein
sympathomimetic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117248T
Other languages
English (en)
Inventor
Johann Dr Eibl
Ludwig Prof Dr Pichler
Hans-Peter Doz Dr Schwarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno AG filed Critical Immuno AG
Application granted granted Critical
Publication of ES2102435T3 publication Critical patent/ES2102435T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION CONCIERNE A LA UTILIZACION DE PROTEINA C ACTIVADA PARA LA PRODUCCION DE UN PREPARADO FARMACEUTICO CON EFECTO ANTINOCICEPTIVO. ESTE PREPARADO FARMACEUTICO ES APROPIADO PARA EL TRATAMIENTO DE ESTADOS DOLOROSOS, COMO LOS QUE SE ORIGINAN POR PROCESOS INFLAMATORIOS AGUDOS O CRONICOS (ARTRITIS REUMATOIDE, MIOSITIS, GASTRITIS, COLITIS, INFLAMACIONES EN EL TRACTO UROGENITAL). TAMBIEN SE EMPLEA LA PROTEINA C PARA LA PRODUCCION DE UN PREPARADO FARMACEUTICO PARA LA NORMALIZACION DE UNA PERMEABILIDAD CIRCULATORIA AUMENTADA Y PARA LA ESTIMULACION DE LOS ADRENORRECEPTORES (BETA).
ES92117248T 1990-08-16 1991-01-28 Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico. Expired - Lifetime ES2102435T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0169790A AT402260B (de) 1990-08-16 1990-08-16 Protein c-hältige pharmazeutische präparation

Publications (1)

Publication Number Publication Date
ES2102435T3 true ES2102435T3 (es) 1997-08-01

Family

ID=3519039

Family Applications (3)

Application Number Title Priority Date Filing Date
ES91890012T Expired - Lifetime ES2080289T3 (es) 1990-08-16 1991-01-28 Proteina c para el tratamiento del dolor.
ES92117248T Expired - Lifetime ES2102435T3 (es) 1990-08-16 1991-01-28 Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico.
ES92117249T Expired - Lifetime ES2103861T3 (es) 1990-08-16 1991-01-28 Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES91890012T Expired - Lifetime ES2080289T3 (es) 1990-08-16 1991-01-28 Proteina c para el tratamiento del dolor.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES92117249T Expired - Lifetime ES2103861T3 (es) 1990-08-16 1991-01-28 Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio.

Country Status (12)

Country Link
EP (3) EP0533210B1 (es)
JP (1) JP2530770B2 (es)
AT (6) AT402260B (es)
CA (1) CA2041380C (es)
CZ (1) CZ280004B6 (es)
DE (3) DE59108697D1 (es)
DK (3) DK0471660T3 (es)
ES (3) ES2080289T3 (es)
HR (1) HRP921237A2 (es)
HU (1) HUT60147A (es)
RU (1) RU2066550C1 (es)
YU (1) YU77591A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571786A (en) * 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
AT397615B (de) * 1991-05-14 1994-05-25 Immuno Ag Arzneimittel enthaltend protein c
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
ES2179129T3 (es) * 1995-03-21 2003-01-16 Baxter Ag Agente para la aplicacion subcutanea de la proteina c.
DE19608218A1 (de) * 1995-03-21 1996-09-26 Immuno Ag Mittel zur subkutanen Verabreichung von Protein C
WO2006072137A1 (en) * 2005-01-07 2006-07-13 Northern Sydney And Central Coast Area Health Service Treatment for autoimmune and inflammatory conditions
JP6273272B2 (ja) 2012-07-04 2018-01-31 ジージー バイオテック エルエルシー 炎症性皮膚障害の治療
JP2017513944A (ja) 2014-04-16 2017-06-01 ジージー バイオテック エルエルシー 異常な皮膚瘢痕化の治療
CA2946032C (en) 2014-04-16 2022-06-14 Zz Biotech Llc Use of apc analogue for wound healing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2739050B2 (ja) * 1988-01-28 1998-04-08 ヘキスト薬品工業株式会社 抗血液凝固剤
US5093117A (en) * 1989-01-24 1992-03-03 Baxter International Inc. Compositions and method for the treatment or prophylaxis of sepsis or septic shock

Also Published As

Publication number Publication date
EP0471660B1 (de) 1995-08-23
DK0471660T3 (da) 1995-12-18
ATE126699T1 (de) 1995-09-15
RU2066550C1 (ru) 1996-09-20
JP2530770B2 (ja) 1996-09-04
YU77591A (sh) 1995-10-24
AT403439B (de) 1998-02-25
EP0471660A3 (en) 1992-04-15
HU911348D0 (en) 1991-10-28
DK0533209T3 (da) 1997-09-22
CA2041380A1 (en) 1992-02-17
ATE150649T1 (de) 1997-04-15
EP0471660A2 (de) 1992-02-19
CZ280004B6 (cs) 1995-09-13
DE59106292D1 (de) 1995-09-28
CS121391A3 (en) 1992-02-19
EP0533210B1 (de) 1997-05-02
AT402260B (de) 1997-03-25
DE59108638D1 (de) 1997-04-30
ATA169790A (de) 1996-08-15
ATA20492A (de) 1997-10-15
EP0533209A1 (de) 1993-03-24
EP0533209B1 (de) 1997-03-26
EP0533210A1 (de) 1993-03-24
CA2041380C (en) 1997-10-07
ATE152354T1 (de) 1997-05-15
ES2103861T3 (es) 1997-10-01
ES2080289T3 (es) 1996-02-01
DE59108697D1 (de) 1997-06-05
HUT60147A (en) 1992-08-28
AT403763B (de) 1998-05-25
HRP921237A2 (en) 1995-10-31
JPH04230633A (ja) 1992-08-19
DK0533210T3 (da) 1997-11-03
ATA20392A (de) 1997-07-15

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