ES2103861T3 - Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio. - Google Patents

Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio.

Info

Publication number
ES2103861T3
ES2103861T3 ES92117249T ES92117249T ES2103861T3 ES 2103861 T3 ES2103861 T3 ES 2103861T3 ES 92117249 T ES92117249 T ES 92117249T ES 92117249 T ES92117249 T ES 92117249T ES 2103861 T3 ES2103861 T3 ES 2103861T3
Authority
ES
Spain
Prior art keywords
pharmaceutical preparations
inflammatory agent
containing protein
preparations containing
compsn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92117249T
Other languages
English (en)
Inventor
Johann Dr Eibl
Ludwig Prof Dr Pichler
Hans-Peter Doz Dr Schwarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno AG filed Critical Immuno AG
Application granted granted Critical
Publication of ES2103861T3 publication Critical patent/ES2103861T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

LA INVENCION CONCIERNE A LA UTILIZACION DE PROTEINA C O PROTEINA C ACTIVADA PARA LA PRODUCCION DE UN PREPARADO FARMACEUTICO CON EFECTO ANTINOCICEPTIVO. ESTE PREPARADO FARMACEUTICO ES APROPIADO PARA EL TRATAMIENTO DE ESTADOS DOLOROSOS, COMO LOS QUE SE ORIGINAN MEDIANTE PROCESOS INFLAMATORIOS AGUDOS O CRONICOS (ARTRITIS REUMATOIDE, MIOSITIS, GASTRITIS, COLITIS, INFLAMACIONES EN EL TRACTO URO-GENITAL). TAMBIEN SE EMPLEA LA PROTEINA C PARA LA PRODUCCION DE UN PREPARADO FARMACEUTICO PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS AGUDAS O CRONICAS.
ES92117249T 1990-08-16 1991-01-28 Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio. Expired - Lifetime ES2103861T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0169790A AT402260B (de) 1990-08-16 1990-08-16 Protein c-hältige pharmazeutische präparation

Publications (1)

Publication Number Publication Date
ES2103861T3 true ES2103861T3 (es) 1997-10-01

Family

ID=3519039

Family Applications (3)

Application Number Title Priority Date Filing Date
ES92117249T Expired - Lifetime ES2103861T3 (es) 1990-08-16 1991-01-28 Preparaciones farmaceuticas que contienen proteina c como agente antiinflamatorio.
ES91890012T Expired - Lifetime ES2080289T3 (es) 1990-08-16 1991-01-28 Proteina c para el tratamiento del dolor.
ES92117248T Expired - Lifetime ES2102435T3 (es) 1990-08-16 1991-01-28 Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES91890012T Expired - Lifetime ES2080289T3 (es) 1990-08-16 1991-01-28 Proteina c para el tratamiento del dolor.
ES92117248T Expired - Lifetime ES2102435T3 (es) 1990-08-16 1991-01-28 Preparacion farmaceutica que contiene la proteina c como agente beta-simpatomimetico.

Country Status (12)

Country Link
EP (3) EP0471660B1 (es)
JP (1) JP2530770B2 (es)
AT (6) AT402260B (es)
CA (1) CA2041380C (es)
CZ (1) CZ280004B6 (es)
DE (3) DE59108697D1 (es)
DK (3) DK0471660T3 (es)
ES (3) ES2103861T3 (es)
HR (1) HRP921237A2 (es)
HU (1) HUT60147A (es)
RU (1) RU2066550C1 (es)
YU (1) YU77591A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571786A (en) * 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
AT397615B (de) * 1991-05-14 1994-05-25 Immuno Ag Arzneimittel enthaltend protein c
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
ES2179129T3 (es) * 1995-03-21 2003-01-16 Baxter Ag Agente para la aplicacion subcutanea de la proteina c.
DE19608218A1 (de) * 1995-03-21 1996-09-26 Immuno Ag Mittel zur subkutanen Verabreichung von Protein C
EP1841442A4 (en) * 2005-01-07 2009-12-09 Northern Sydney And Central Co TREATMENT OF AUTOIMMUNE DISEASES AND INFLAMMATORY DISEASES
ES2676422T3 (es) * 2012-07-04 2018-07-19 Zz Biotech Llc Proteína C activada para su uso en el tratamiento de trastornos inflamatorios de la piel
PT3131572T (pt) 2014-04-16 2021-09-24 Zz Biotech Llc Análogo de apc para utilização em cicatrização de feridas
ES2890675T3 (es) 2014-04-16 2022-01-21 Zz Biotech Llc APC para uso en el tratamiento de cicatrices cutáneas anormales

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2739050B2 (ja) * 1988-01-28 1998-04-08 ヘキスト薬品工業株式会社 抗血液凝固剤
US5093117A (en) * 1989-01-24 1992-03-03 Baxter International Inc. Compositions and method for the treatment or prophylaxis of sepsis or septic shock

Also Published As

Publication number Publication date
CA2041380A1 (en) 1992-02-17
HUT60147A (en) 1992-08-28
CS121391A3 (en) 1992-02-19
ATE126699T1 (de) 1995-09-15
EP0471660A2 (de) 1992-02-19
ATA20392A (de) 1997-07-15
DK0533210T3 (da) 1997-11-03
HRP921237A2 (en) 1995-10-31
JPH04230633A (ja) 1992-08-19
ATE152354T1 (de) 1997-05-15
ES2080289T3 (es) 1996-02-01
RU2066550C1 (ru) 1996-09-20
DK0471660T3 (da) 1995-12-18
ATA20492A (de) 1997-10-15
AT403763B (de) 1998-05-25
CZ280004B6 (cs) 1995-09-13
AT403439B (de) 1998-02-25
ATE150649T1 (de) 1997-04-15
EP0533210B1 (de) 1997-05-02
ATA169790A (de) 1996-08-15
EP0471660A3 (en) 1992-04-15
DE59108697D1 (de) 1997-06-05
AT402260B (de) 1997-03-25
DE59108638D1 (de) 1997-04-30
DK0533209T3 (da) 1997-09-22
HU911348D0 (en) 1991-10-28
EP0533210A1 (de) 1993-03-24
JP2530770B2 (ja) 1996-09-04
CA2041380C (en) 1997-10-07
EP0533209B1 (de) 1997-03-26
ES2102435T3 (es) 1997-08-01
EP0533209A1 (de) 1993-03-24
DE59106292D1 (de) 1995-09-28
EP0471660B1 (de) 1995-08-23
YU77591A (sh) 1995-10-24

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