ES2102761T3 - Propanodioatos aromaticos yodados y su uso como agentes de contraste a los rayos x. - Google Patents

Propanodioatos aromaticos yodados y su uso como agentes de contraste a los rayos x.

Info

Publication number
ES2102761T3
ES2102761T3 ES94200746T ES94200746T ES2102761T3 ES 2102761 T3 ES2102761 T3 ES 2102761T3 ES 94200746 T ES94200746 T ES 94200746T ES 94200746 T ES94200746 T ES 94200746T ES 2102761 T3 ES2102761 T3 ES 2102761T3
Authority
ES
Spain
Prior art keywords
aromatic
propanodioates
irodated
rays
contract agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94200746T
Other languages
English (en)
Inventor
Edward R Bacon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanosystems LLC
Original Assignee
Nanosystems LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosystems LLC filed Critical Nanosystems LLC
Application granted granted Critical
Publication of ES2102761T3 publication Critical patent/ES2102761T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

LOS COMPUESTOS QUE TIENEN LA ESTRUCTURA EN LA QUE (Z)-COOO ES EL RESIDUO DE UN ACIDO AROMATICO YODADO; R1 Y R2 SON INDEPENDIENTEMENTE ALKILO, FLUORALKILO, CICLOALKILO, ARILO O ARALKILO; Y R3 ES H, ALKILO, FLUORALKILO, CICLOALKILO, ARILO, ARALKILO, ALCOXI, ARILOXI, CIANO, SULFONATO, CARBOXAMIDO, SULFONAMIDO, CO2-ALKILO, CO2-ARILO O CO2-ARALKILO; SON UTILES COMO AGENTES DE CONTRASTE EN COMPOSICIONES FORMADORAS DE IMAGENES DE RAYOS X Y PARA LOS METODOS DE FORMACION DE IMAGENES DE DIAGNOSTICO.
ES94200746T 1993-03-29 1994-03-23 Propanodioatos aromaticos yodados y su uso como agentes de contraste a los rayos x. Expired - Lifetime ES2102761T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/038,371 US5264610A (en) 1993-03-29 1993-03-29 Iodinated aromatic propanedioates

Publications (1)

Publication Number Publication Date
ES2102761T3 true ES2102761T3 (es) 1997-08-01

Family

ID=21899562

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94200746T Expired - Lifetime ES2102761T3 (es) 1993-03-29 1994-03-23 Propanodioatos aromaticos yodados y su uso como agentes de contraste a los rayos x.

Country Status (16)

Country Link
US (2) US5264610A (es)
EP (1) EP0618189B1 (es)
JP (1) JPH06321868A (es)
AT (1) ATE153998T1 (es)
AU (1) AU670357B2 (es)
CA (1) CA2119968A1 (es)
CZ (1) CZ68894A3 (es)
DE (1) DE69403534T2 (es)
ES (1) ES2102761T3 (es)
FI (1) FI941458A7 (es)
HU (1) HUT66945A (es)
IL (1) IL109138A0 (es)
NO (1) NO941162L (es)
NZ (1) NZ260194A (es)
PH (1) PH30892A (es)
SK (1) SK36094A3 (es)

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Also Published As

Publication number Publication date
US5264610A (en) 1993-11-23
HU9400894D0 (en) 1994-06-28
HUT66945A (en) 1995-01-30
NZ260194A (en) 1995-12-21
IL109138A0 (en) 1994-06-24
NO941162L (no) 1994-09-30
AU5906594A (en) 1994-10-06
FI941458L (fi) 1994-09-30
ATE153998T1 (de) 1997-06-15
SK36094A3 (en) 1994-11-09
PH30892A (en) 1997-12-23
US5328404A (en) 1994-07-12
JPH06321868A (ja) 1994-11-22
FI941458A7 (fi) 1994-09-30
AU670357B2 (en) 1996-07-11
CZ68894A3 (en) 1994-11-16
DE69403534D1 (de) 1997-07-10
EP0618189A1 (en) 1994-10-05
EP0618189B1 (en) 1997-06-04
NO941162D0 (no) 1994-03-29
FI941458A0 (fi) 1994-03-29
CA2119968A1 (en) 1994-09-30
DE69403534T2 (de) 1997-12-11

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