ES2105641T3 - Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. - Google Patents

Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.

Info

Publication number
ES2105641T3
ES2105641T3 ES94906606T ES94906606T ES2105641T3 ES 2105641 T3 ES2105641 T3 ES 2105641T3 ES 94906606 T ES94906606 T ES 94906606T ES 94906606 T ES94906606 T ES 94906606T ES 2105641 T3 ES2105641 T3 ES 2105641T3
Authority
ES
Spain
Prior art keywords
formulation
growth
bones
causes
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906606T
Other languages
English (en)
Inventor
Arthur J Ammann
Steven L Beck
Tue H Nguyen
Boonsri Ongpipattanakul
Christopher G Rudman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2105641T3 publication Critical patent/ES2105641T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

SE PROPORCIONA UNA FORMULACION PARA TRANSFORMAR EL FACTOR DE CRECIMIENTO {BE} QUE CONTIENE FOSFATO TRICALCICO, PREFERIBLEMENTE EN LA FORMA DE PARTICULAS COMO GRANULOS. LA FORMULACION CONTIENE OPCIONALMENTE UN POLIMERO COMO AMILOPECTINA PARA MEJORAR LA CONSISTENCIA DE LA FORMULACION.
ES94906606T 1993-01-12 1994-01-11 Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. Expired - Lifetime ES2105641T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US336593A 1993-01-12 1993-01-12

Publications (1)

Publication Number Publication Date
ES2105641T3 true ES2105641T3 (es) 1997-10-16

Family

ID=21705523

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906606T Expired - Lifetime ES2105641T3 (es) 1993-01-12 1994-01-11 Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.

Country Status (10)

Country Link
EP (1) EP0679097B1 (es)
JP (1) JP3347144B2 (es)
AT (1) ATE153535T1 (es)
AU (1) AU671721B2 (es)
CA (1) CA2151486A1 (es)
DE (1) DE69403439T2 (es)
DK (1) DK0679097T3 (es)
ES (1) ES2105641T3 (es)
GR (1) GR3024277T3 (es)
WO (1) WO1994015653A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503558A (en) * 1993-11-12 1996-04-02 Mcgill University Osseointegration promoting implant composition, implant assembly and method therefor
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
JP4388602B2 (ja) † 1997-02-07 2009-12-24 ストライカー コーポレイション マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
NL1008582C2 (nl) * 1998-01-05 1999-07-06 Vrije Universiteit Botmateriaal.
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
DE69903732T2 (de) * 1998-07-02 2003-07-03 Stichting Skeletal Tissue Engineering Group Amsterdam, Amsterdam Knochenzement mit antimikrobiellen peptiden
EP0992251A1 (en) * 1998-10-07 2000-04-12 Isotis B.V. Device for tissue engineering a bone equivalent
IT1302534B1 (it) 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
JP2002539172A (ja) * 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Ｔｇｆ−ベータを含む医薬組成物
CA2377435A1 (en) 1999-06-29 2001-01-04 J. Alexander Marchosky Compositions and methods for forming and strengthening bone
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
ES2247423T5 (es) 2001-11-19 2015-12-30 Scil Technology Gmbh Método de producción de un dispositivo recubierto homogéneamente que tiene propiedades osteoinductoras y osteoconductoras
TW200400062A (en) 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7018361B2 (en) 2002-06-14 2006-03-28 Baxter International Inc. Infusion pump
US7384652B2 (en) 2002-06-24 2008-06-10 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Complexed-acidic-phospholipid-collagen composites for bone induction
JP5449638B2 (ja) * 2002-07-31 2014-03-19 デンツプライ インターナショナル インコーポレーテッド 多孔性粒子およびキャリアゲルを含む骨修復パテ
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
ATE322916T1 (de) 2002-09-10 2006-04-15 Scil Technology Gmbh Unter verringerter sauerstoffkonzentration mit einem osteoinduktiven protein beschichtetes metallimplantat
EP1462126A1 (en) * 2003-03-28 2004-09-29 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Improved Osteoinductive Materials
US7534264B2 (en) 2004-01-28 2009-05-19 Ultradent Products, Inc. Delivery system for bone growth promoting material
ATE478008T1 (de) 2004-03-10 2010-09-15 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
EP1880731A1 (en) * 2006-07-18 2008-01-23 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Human growth and differentiation factor GDF-5
EP3345607B1 (en) * 2006-12-29 2022-10-26 Ossifi-Mab LLC Methods of altering bone growth by administration of sost or wise antagonist or agonist
WO2010001578A1 (ja) * 2008-06-30 2010-01-07 国立大学法人東京大学 骨成長因子を吸着し，その活性を阻害しない骨補填剤
AU2011250934B2 (en) 2010-05-11 2016-02-25 Howmedica Osteonics Corp., Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US10688222B2 (en) 2016-11-21 2020-06-23 Warsaw Orthopedic, Inc. Lyophilized moldable implants containing an oxysterol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
IE61346B1 (en) * 1988-11-02 1994-11-02 Genentech Inc A permeable material to fit around the teeth or gums of a mammal
US4976736A (en) * 1989-04-28 1990-12-11 Interpore International Coated biomaterials and methods for making same
US5158934A (en) * 1989-09-01 1992-10-27 Genentech, Inc. Method of inducing bone growth using TGF-β
US5071655A (en) * 1990-01-12 1991-12-10 Baylink David J Pharmaceutical combination for treatment of bone-wasting diseases
US5208219A (en) 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
DE4121043A1 (de) * 1991-06-26 1993-01-07 Merck Patent Gmbh Knochenersatzmaterial mit fgf
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone

Also Published As

Publication number Publication date
EP0679097A1 (en) 1995-11-02
DK0679097T3 (da) 1997-12-22
JP3347144B2 (ja) 2002-11-20
DE69403439T2 (de) 1997-10-23
AU671721B2 (en) 1996-09-05
GR3024277T3 (en) 1997-10-31
DE69403439D1 (de) 1997-07-03
JPH08505548A (ja) 1996-06-18
ATE153535T1 (de) 1997-06-15
EP0679097B1 (en) 1997-05-28
CA2151486A1 (en) 1994-07-21
AU6026294A (en) 1994-08-15
WO1994015653A1 (en) 1994-07-21

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