ES2105641T3 - Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. - Google Patents

Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.

Info

Publication number
ES2105641T3
ES2105641T3 ES94906606T ES94906606T ES2105641T3 ES 2105641 T3 ES2105641 T3 ES 2105641T3 ES 94906606 T ES94906606 T ES 94906606T ES 94906606 T ES94906606 T ES 94906606T ES 2105641 T3 ES2105641 T3 ES 2105641T3
Authority
ES
Spain
Prior art keywords
formulation
growth
bones
causes
growth factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906606T
Other languages
English (en)
Inventor
Arthur J Ammann
Steven L Beck
Tue H Nguyen
Boonsri Ongpipattanakul
Christopher G Rudman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2105641T3 publication Critical patent/ES2105641T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

SE PROPORCIONA UNA FORMULACION PARA TRANSFORMAR EL FACTOR DE CRECIMIENTO {BE} QUE CONTIENE FOSFATO TRICALCICO, PREFERIBLEMENTE EN LA FORMA DE PARTICULAS COMO GRANULOS. LA FORMULACION CONTIENE OPCIONALMENTE UN POLIMERO COMO AMILOPECTINA PARA MEJORAR LA CONSISTENCIA DE LA FORMULACION.
ES94906606T 1993-01-12 1994-01-11 Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos. Expired - Lifetime ES2105641T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US336593A 1993-01-12 1993-01-12

Publications (1)

Publication Number Publication Date
ES2105641T3 true ES2105641T3 (es) 1997-10-16

Family

ID=21705523

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906606T Expired - Lifetime ES2105641T3 (es) 1993-01-12 1994-01-11 Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.

Country Status (10)

Country Link
EP (1) EP0679097B1 (es)
JP (1) JP3347144B2 (es)
AT (1) ATE153535T1 (es)
AU (1) AU671721B2 (es)
CA (1) CA2151486A1 (es)
DE (1) DE69403439T2 (es)
DK (1) DK0679097T3 (es)
ES (1) ES2105641T3 (es)
GR (1) GR3024277T3 (es)
WO (1) WO1994015653A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503558A (en) * 1993-11-12 1996-04-02 Mcgill University Osseointegration promoting implant composition, implant assembly and method therefor
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
US5776193A (en) * 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
EP0957943B2 (en) † 1997-02-07 2008-11-26 Stryker Corporation Matrix-free osteogenic devices, implants and methods of use thereof
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
NL1008582C2 (nl) * 1998-01-05 1999-07-06 Vrije Universiteit Botmateriaal.
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
ATE226836T1 (de) * 1998-07-02 2002-11-15 Stichting Skeletal Tissue Engi Knochenzement mit antimikrobiellen peptiden
EP0992251A1 (en) * 1998-10-07 2000-04-12 Isotis B.V. Device for tissue engineering a bone equivalent
IT1302534B1 (it) 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
AU3556400A (en) 1999-03-17 2000-10-04 Novartis Ag Pharmaceutical compositions
WO2001000792A1 (en) 1999-06-29 2001-01-04 Marchosky J Alexander Compositions and methods for forming and strengthening bone
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
TW200400062A (en) 2002-04-03 2004-01-01 Mathys Medizinaltechnik Ag Kneadable, pliable bone replacement material
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US7018361B2 (en) 2002-06-14 2006-03-28 Baxter International Inc. Infusion pump
WO2004000232A2 (en) 2002-06-24 2003-12-31 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Complexed-acidic-phospholipid-collagen composites for bone induction
EP1525011B1 (en) * 2002-07-31 2016-08-17 DENTSPLY International Inc. Bone repair putty comprising porous particulate and carrier gel
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
AU2003253049A1 (en) 2002-09-10 2004-04-30 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
EP1462126A1 (en) * 2003-03-28 2004-09-29 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Improved Osteoinductive Materials
US7534264B2 (en) 2004-01-28 2009-05-19 Ultradent Products, Inc. Delivery system for bone growth promoting material
US8372419B2 (en) 2004-03-10 2013-02-12 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
EP1880731A1 (en) * 2006-07-18 2008-01-23 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Human growth and differentiation factor GDF-5
WO2009131553A2 (en) * 2006-12-29 2009-10-29 Osteogenex Inc. Methods of altering bone growth by administration of sost or wise antagonist or agonist
JPWO2010001578A1 (ja) * 2008-06-30 2011-12-15 株式会社ネクスト２１ 骨成長因子を吸着し，その活性を阻害しない骨補填剤
CA3048850A1 (en) 2010-05-11 2011-11-17 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US10688222B2 (en) 2016-11-21 2020-06-23 Warsaw Orthopedic, Inc. Lyophilized moldable implants containing an oxysterol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
IE61346B1 (en) * 1988-11-02 1994-11-02 Genentech Inc A permeable material to fit around the teeth or gums of a mammal
US4976736A (en) * 1989-04-28 1990-12-11 Interpore International Coated biomaterials and methods for making same
US5158934A (en) 1989-09-01 1992-10-27 Genentech, Inc. Method of inducing bone growth using TGF-β
US5071655A (en) * 1990-01-12 1991-12-10 Baylink David J Pharmaceutical combination for treatment of bone-wasting diseases
US5208219A (en) 1991-02-14 1993-05-04 Celtrix Pharmaceuticals Inc. Method for inducing bone growth
DE4121043A1 (de) * 1991-06-26 1993-01-07 Merck Patent Gmbh Knochenersatzmaterial mit fgf
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone

Also Published As

Publication number Publication date
EP0679097B1 (en) 1997-05-28
JP3347144B2 (ja) 2002-11-20
EP0679097A1 (en) 1995-11-02
AU6026294A (en) 1994-08-15
DK0679097T3 (da) 1997-12-22
JPH08505548A (ja) 1996-06-18
WO1994015653A1 (en) 1994-07-21
GR3024277T3 (en) 1997-10-31
ATE153535T1 (de) 1997-06-15
DE69403439T2 (de) 1997-10-23
DE69403439D1 (de) 1997-07-03
CA2151486A1 (en) 1994-07-21
AU671721B2 (en) 1996-09-05

Similar Documents

Publication Publication Date Title
ES2105641T3 (es) Formulacion del factor de crecimiento de transformacion beta que provoca el crecimiento de los huesos.
MX9709874A (es) N-(INDOL-2-CARBONIL) beta-ALANILAMIDAS SUSTITUIDAS Y DERIVADOS COMO INHIBIDORES DE GLUCOGENO FOSFORILASA, USO DE LOS MISMOS Y COMPOSICIONES QUE LOS CONTIENEN.
FI925845A0 (fi) Biokeramiskt system foer avgivande av bioaktiva aemnen
HN1998000157A (es) Agonistas de prostaglandinas
ES2179207T3 (es) Formulaciones de hierro dextrano.
CO4600700A1 (es) Composicion agricola y agente de acondicionamiento para la reduccion de la hidroscopicidad y la formacion de polvo en fertilizantes
MX9709278A (es) Dipeptidos que promueven la liberacion de la hormona de crecimiento, composiciones que los contienen y uso de los mismos.
MX9301047A (es) Recubrimiento para la reduccion del arrastre del tejido.
MX9307569A (es) Formulacion de mezcla seca para acidos bisfosfonicos.
ATE197124T1 (de) Wirkstoffe und gas enthaltende mikropartikel
ATE279950T1 (de) Zusammensetzung zur implantation in den menschlichen und tierischen körper
ES2158588T3 (es) Composiciones y procedimientos para el beneficio de menas.
ES2152196T3 (es) Implante para vertebra.
WO2001054746A3 (en) Composite biomaterial including anisometric calcium phosphate reinforcement particles
ES2190431T3 (es) Soluciones estables al almacenaje de sistemas de acelerantes para resinas epoxi.
ES2109423T3 (es) Metodo de preparacion de componentes y dispositivos opticos en sus dimensiones finales o casi finales.
ES2078277T3 (es) Una nueva arginina desiminasa, su metodo de fabricacion y un agente anti-cancer que contiene esta enzima como un ingrediente eficaz.
AU5994386A (en) Bone cement
ES2095068T3 (es) Peroxicarbonatos polimericos y procedimiento para prepararlos.
ES2056978T3 (es) Articulo protesico.
AR010903A1 (es) Preparacion farmaceutica, un procedimiento para prepararla y su empleo en calidad de medicamento.
MX9300558A (es) Nueva sulfonilurea, procedimiento para su preparacion y formulado farmaceutico que la contiene.
MX9300406A (es) Derivados azabiciclicos procedimientos para su preparacion y composiciones que los contienen.
ES2113962T3 (es) Fertilizante de sustancias naturales de tres fases biologicamente puro y procedimiento para la fabricacion del mismo.
MX9204815A (es) Hexahidrobenzo[f]quinolinonas y formulacion farmaceutica que las comprende.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 679097

Country of ref document: ES