ATE156915T1 - Testsysteme unter verwendung von gewebeäquivalenten - Google Patents

Testsysteme unter verwendung von gewebeäquivalenten

Info

Publication number
ATE156915T1
ATE156915T1 AT88302953T AT88302953T ATE156915T1 AT E156915 T1 ATE156915 T1 AT E156915T1 AT 88302953 T AT88302953 T AT 88302953T AT 88302953 T AT88302953 T AT 88302953T AT E156915 T1 ATE156915 T1 AT E156915T1
Authority
AT
Austria
Prior art keywords
tissue
test systems
limited
tissue equivalents
agent
Prior art date
Application number
AT88302953T
Other languages
English (en)
Inventor
Eugene Bell
Crispin Weinburg
Original Assignee
Organogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE156915(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organogenesis Inc filed Critical Organogenesis Inc
Application granted granted Critical
Publication of ATE156915T1 publication Critical patent/ATE156915T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
AT88302953T 1987-03-31 1988-03-31 Testsysteme unter verwendung von gewebeäquivalenten ATE156915T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/032,848 US4835102A (en) 1987-03-31 1987-03-31 Tissue equivalent test systems

Publications (1)

Publication Number Publication Date
ATE156915T1 true ATE156915T1 (de) 1997-08-15

Family

ID=21867144

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88302953T ATE156915T1 (de) 1987-03-31 1988-03-31 Testsysteme unter verwendung von gewebeäquivalenten

Country Status (9)

Country Link
US (1) US4835102A (de)
EP (1) EP0295762B1 (de)
JP (1) JP2767803B2 (de)
AT (1) ATE156915T1 (de)
CA (1) CA1305913C (de)
DE (1) DE3855991T2 (de)
ES (1) ES2106010T3 (de)
GR (1) GR3025046T3 (de)
IL (1) IL85599A (de)

Families Citing this family (76)

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WO1993017336A1 (en) * 1992-02-19 1993-09-02 The Procter & Gamble Company In vitro model for eye and skin irritation testing
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US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
US5585265A (en) * 1992-11-30 1996-12-17 Gillette Company Human corneal epithelial cell lines with extended lifespan
US5656492A (en) * 1993-02-12 1997-08-12 Brigham And Women's Hospital, Inc. Cell induction device
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
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US5672498A (en) * 1993-12-28 1997-09-30 The Gillete Company Human corneal epithelial cell lines with extended lifespan
EP0871414B1 (de) * 1994-03-14 2004-04-28 Cryolife, Inc Herstellungsverfahren von gewebe zur implantation
WO1995029647A2 (en) * 1994-04-29 1995-11-09 Scimed Life Systems, Inc. Stent with collagen
JP2858087B2 (ja) * 1994-09-19 1999-02-17 グンゼ株式会社 組織培養用基材及び組織培養法
US5948654A (en) 1996-08-28 1999-09-07 Univ Minnesota Magnetically oriented tissue-equivalent and biopolymer tubes comprising collagen
US6057137A (en) 1994-10-06 2000-05-02 Regents Of The University Of Minnesota Tissue-equivalent rods containing aligned collagen fibrils and schwann cells
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US20040002772A1 (en) * 1995-04-28 2004-01-01 Organogenesis, Inc. Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents
US5814328A (en) * 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US5846188A (en) * 1997-01-17 1998-12-08 Palti; Yoram Sensor utilizing living muscle cells
JP3408258B2 (ja) 1997-03-11 2003-05-19 ポーラ化成工業株式会社 皮膚状態改善剤の評価方法及び皮膚外用剤の製造方法
US7687057B2 (en) * 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US6066495A (en) * 1998-03-05 2000-05-23 Tissue Engineering, Inc. Methods and apparatus for the conditioning of ligament replacement tissue
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US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
US6293970B1 (en) * 1998-06-30 2001-09-25 Lifenet Plasticized bone and soft tissue grafts and methods of making and using same
US7063726B2 (en) * 1998-06-30 2006-06-20 Lifenet Plasticized bone grafts and methods of making and using same
US8563232B2 (en) 2000-09-12 2013-10-22 Lifenet Health Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced
US20100030340A1 (en) * 1998-06-30 2010-02-04 Wolfinbarger Jr Lloyd Plasticized Grafts and Methods of Making and Using Same
AT407047B (de) * 1998-08-03 2000-11-27 Pfaller Walter Dr Zellkulturvorrichtung
WO2000029553A1 (en) 1998-11-19 2000-05-25 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
US6030789A (en) * 1999-03-10 2000-02-29 The Gillette Company Human conjunctival epithelial cell lines with an extended life span
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US20040023907A1 (en) * 2000-05-31 2004-02-05 Christoph Dieterich Infection model
US7172859B2 (en) * 2000-07-14 2007-02-06 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
US6852526B2 (en) * 2000-07-14 2005-02-08 Transform Pharmaceuticals, Inc. Transdermal assay with magnetic clamp
AU7788701A (en) * 2000-07-14 2002-01-30 Transform Pharmaceuticals Inc System and method for optimizing tissue barrier transfer of compounds
US20080182293A1 (en) * 2000-07-14 2008-07-31 Transform Pharmaceuticals, Inc. Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
AU2002341867A1 (en) * 2001-09-27 2003-04-07 The Wistar Institute Methods and compositions for monitoring cell migration and identifying clinically relevant cytotoxic t lymphocyte activity
WO2003041568A2 (en) * 2001-11-15 2003-05-22 University Of Medicine & Dentistry Of New Jersey A three-dimensional matrix for producing living tissue equivalents
US20040219659A1 (en) * 2002-04-22 2004-11-04 Altman Gregory H. Multi-dimensional strain bioreactor
AUPS242702A0 (en) * 2002-05-21 2002-06-13 Colltech Australia Limited Improved method for the extraction and purification of collagen
US7229820B2 (en) 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
AU2003242967A1 (en) * 2002-07-12 2004-02-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method and device for inducing biological processes by micro-organs
US6908760B2 (en) * 2002-10-28 2005-06-21 Transform Pharmaceuticals, Inc. Raised surface assay plate
US7449307B2 (en) * 2002-10-28 2008-11-11 Transform Pharmaceuticals, Inc. Raised surface assay plate
US20040185430A1 (en) * 2002-12-20 2004-09-23 Marc Andre Lefebvre Process for evaluating the cosmetic or dermatological activity of a product and use of plant material
US9744043B2 (en) 2007-07-16 2017-08-29 Lifenet Health Crafting of cartilage
CN101918532B (zh) * 2007-08-22 2016-03-30 普罗柏欧贞股份公司 用于体外测试免疫原性和免疫功能的培养系统和方法
US9535056B2 (en) * 2008-01-10 2017-01-03 L'oreal Immune system modeling devices and methods
DK3404093T3 (da) 2008-07-16 2020-03-16 Childrens Medical Center Anordning og fremgangsmåde til overvågning af celleadfærd
WO2011126980A1 (en) * 2010-04-05 2011-10-13 Millipore Corporation Polymeric membranes with human skin like permeability properties and uses thereof
EP2681306B1 (de) 2011-02-28 2019-01-09 President and Fellows of Harvard College Zellkultursystem
US9725687B2 (en) 2011-12-09 2017-08-08 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2725094A1 (de) * 2012-10-29 2014-04-30 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Epithelgewebemodell
WO2015013332A1 (en) 2013-07-22 2015-01-29 President And Fellows Of Harvard College Microfluidic cartridge assembly
GB2583047B (en) 2013-12-20 2021-03-24 Harvard College Organomimetic devices and methods of use and manufacturing thereof
US11119093B2 (en) 2013-12-20 2021-09-14 President And Fellows Of Harvard College Low shear microfluidic devices and methods of use and manufacturing thereof
GB2546424A (en) 2014-07-14 2017-07-19 Harvard College Systems and methods for improved performance of fluidic and microfluidic systems
WO2017019542A1 (en) 2015-07-24 2017-02-02 President And Fellows Of Harvard College Radial microfluidic devices and methods of use
US12104174B2 (en) 2016-09-13 2024-10-01 President And Fellows Of Harvard College Methods relating to intestinal organ-on-a-chip
CN112980690B (zh) * 2019-12-17 2022-10-21 华东数字医学工程研究院 Pdx模型孵育装置和抗肿瘤药物筛选方法
AU2022302088A1 (en) * 2021-07-01 2024-01-18 Ambient Biosciences, Inc. Device for vitrifying and delivering vitrified bioactive agents

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US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
WO1983002953A1 (en) * 1982-02-19 1983-09-01 Endotronics Inc Process and apparatus for controlling patterns of chemicals stimuli administration to biological tissue
US4629686A (en) * 1982-02-19 1986-12-16 Endotronics, Inc. Apparatus for delivering a controlled dosage of a chemical substance
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4485097A (en) * 1982-05-26 1984-11-27 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
JPS6110136A (ja) * 1984-06-25 1986-01-17 Fumio Itatsu 油圧機器の圧力調整装置
JPS6134832A (ja) * 1984-07-26 1986-02-19 Hitachi Ltd 大口径イオン源
JPS6133593A (ja) * 1984-07-26 1986-02-17 株式会社東芝 防犯装置
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
US4760020A (en) * 1985-05-03 1988-07-26 Eye Research Institute Of Retina Foundation Method for testing biocompatibility

Also Published As

Publication number Publication date
DE3855991T2 (de) 1998-01-22
IL85599A0 (en) 1988-08-31
EP0295762A3 (de) 1990-07-04
US4835102A (en) 1989-05-30
CA1305913C (en) 1992-08-04
EP0295762A2 (de) 1988-12-21
ES2106010T3 (es) 1997-11-01
DE3855991D1 (de) 1997-09-18
JP2767803B2 (ja) 1998-06-18
EP0295762B1 (de) 1997-08-13
GR3025046T3 (en) 1998-01-30
IL85599A (en) 1991-11-21
JPS63296699A (ja) 1988-12-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee