ATE156915T1 - Testsysteme unter verwendung von gewebeäquivalenten - Google Patents
Testsysteme unter verwendung von gewebeäquivalentenInfo
- Publication number
- ATE156915T1 ATE156915T1 AT88302953T AT88302953T ATE156915T1 AT E156915 T1 ATE156915 T1 AT E156915T1 AT 88302953 T AT88302953 T AT 88302953T AT 88302953 T AT88302953 T AT 88302953T AT E156915 T1 ATE156915 T1 AT E156915T1
- Authority
- AT
- Austria
- Prior art keywords
- tissue
- test systems
- limited
- tissue equivalents
- agent
- Prior art date
Links
- 210000001519 tissue Anatomy 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 210000002808 connective tissue Anatomy 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000000981 epithelium Anatomy 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 210000004907 gland Anatomy 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000002669 organ and tissue protective effect Effects 0.000 abstract 1
- 239000003223 protective agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/032,848 US4835102A (en) | 1987-03-31 | 1987-03-31 | Tissue equivalent test systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE156915T1 true ATE156915T1 (de) | 1997-08-15 |
Family
ID=21867144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88302953T ATE156915T1 (de) | 1987-03-31 | 1988-03-31 | Testsysteme unter verwendung von gewebeäquivalenten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4835102A (de) |
| EP (1) | EP0295762B1 (de) |
| JP (1) | JP2767803B2 (de) |
| AT (1) | ATE156915T1 (de) |
| CA (1) | CA1305913C (de) |
| DE (1) | DE3855991T2 (de) |
| ES (1) | ES2106010T3 (de) |
| GR (1) | GR3025046T3 (de) |
| IL (1) | IL85599A (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5032508A (en) * | 1988-09-08 | 1991-07-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
| US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US5160490A (en) * | 1986-04-18 | 1992-11-03 | Marrow-Tech Incorporated | Three-dimensional cell and tissue culture apparatus |
| US5510254A (en) * | 1986-04-18 | 1996-04-23 | Advanced Tissue Sciences, Inc. | Three dimensional cell and tissue culture system |
| US5053340A (en) * | 1989-02-24 | 1991-10-01 | National Testing Corporation | In vitro test for dermal toxic properties |
| US5175092A (en) * | 1989-05-04 | 1992-12-29 | Millipore Corporation | Vitro toxicology kit and method therefor |
| DE3923279A1 (de) * | 1989-07-14 | 1990-01-18 | Will W Prof Dr Minuth | Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren |
| US5106949A (en) * | 1989-09-15 | 1992-04-21 | Organogenesis, Inc. | Collagen compositions and methods for preparation thereof |
| IL95429A (en) * | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| RU2135191C1 (ru) * | 1990-04-24 | 1999-08-27 | Ортек Интернэшнл, Инк. | Композиционный эквивалент живой кожи, способ его получения, тест-набор |
| US5192312A (en) * | 1991-03-05 | 1993-03-09 | Colorado State University Research Foundation | Treated tissue for implantation and methods of treatment and use |
| US5612188A (en) * | 1991-11-25 | 1997-03-18 | Cornell Research Foundation, Inc. | Automated, multicompartmental cell culture system |
| JPH07503716A (ja) * | 1992-02-04 | 1995-04-20 | オーミクロン コーポレーション | キャプタンの免疫学的類似体 |
| WO1993017336A1 (en) * | 1992-02-19 | 1993-09-02 | The Procter & Gamble Company | In vitro model for eye and skin irritation testing |
| US5478739A (en) * | 1992-10-23 | 1995-12-26 | Advanced Tissue Sciences, Inc. | Three-dimensional stromal cell and tissue culture system |
| US5888720A (en) * | 1992-10-27 | 1999-03-30 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs |
| US5585265A (en) * | 1992-11-30 | 1996-12-17 | Gillette Company | Human corneal epithelial cell lines with extended lifespan |
| US5656492A (en) * | 1993-02-12 | 1997-08-12 | Brigham And Women's Hospital, Inc. | Cell induction device |
| CA2119064A1 (en) * | 1993-03-17 | 1994-09-18 | Richard A. Berg | Dermal-epidermal in vitro test system |
| AU8095094A (en) * | 1993-10-29 | 1995-05-22 | Invitro International | In vitro fluid toxicity bioassay |
| WO1995014221A1 (en) * | 1993-11-18 | 1995-05-26 | Ramsay Hospital Holdings Pty. Ltd. | Processing cassette for tissue samples |
| US5672498A (en) * | 1993-12-28 | 1997-09-30 | The Gillete Company | Human corneal epithelial cell lines with extended lifespan |
| EP0871414B1 (de) * | 1994-03-14 | 2004-04-28 | Cryolife, Inc | Herstellungsverfahren von gewebe zur implantation |
| WO1995029647A2 (en) * | 1994-04-29 | 1995-11-09 | Scimed Life Systems, Inc. | Stent with collagen |
| JP2858087B2 (ja) * | 1994-09-19 | 1999-02-17 | グンゼ株式会社 | 組織培養用基材及び組織培養法 |
| US5948654A (en) | 1996-08-28 | 1999-09-07 | Univ Minnesota | Magnetically oriented tissue-equivalent and biopolymer tubes comprising collagen |
| US6057137A (en) | 1994-10-06 | 2000-05-02 | Regents Of The University Of Minnesota | Tissue-equivalent rods containing aligned collagen fibrils and schwann cells |
| US20030152909A1 (en) * | 1994-11-16 | 2003-08-14 | Mitrani Eduardo N. | In vitro micro-organs, and uses related thereto |
| US6121042A (en) * | 1995-04-27 | 2000-09-19 | Advanced Tissue Sciences, Inc. | Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs |
| US20040002772A1 (en) * | 1995-04-28 | 2004-01-01 | Organogenesis, Inc. | Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents |
| US5814328A (en) * | 1997-01-13 | 1998-09-29 | Gunasekaran; Subramanian | Preparation of collagen using papain and a reducing agent |
| US5846188A (en) * | 1997-01-17 | 1998-12-08 | Palti; Yoram | Sensor utilizing living muscle cells |
| JP3408258B2 (ja) | 1997-03-11 | 2003-05-19 | ポーラ化成工業株式会社 | 皮膚状態改善剤の評価方法及び皮膚外用剤の製造方法 |
| US7687057B2 (en) * | 1998-01-09 | 2010-03-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs, and uses related thereto |
| US6066495A (en) * | 1998-03-05 | 2000-05-23 | Tissue Engineering, Inc. | Methods and apparatus for the conditioning of ligament replacement tissue |
| AU3077299A (en) | 1998-03-11 | 1999-09-27 | University Of Southern California | Method of promoting production of living tissue equivalents |
| US6432710B1 (en) * | 1998-05-22 | 2002-08-13 | Isolagen Technologies, Inc. | Compositions for regenerating tissue that has deteriorated, and methods for using such compositions |
| US6293970B1 (en) * | 1998-06-30 | 2001-09-25 | Lifenet | Plasticized bone and soft tissue grafts and methods of making and using same |
| US7063726B2 (en) * | 1998-06-30 | 2006-06-20 | Lifenet | Plasticized bone grafts and methods of making and using same |
| US8563232B2 (en) | 2000-09-12 | 2013-10-22 | Lifenet Health | Process for devitalizing soft-tissue engineered medical implants, and devitalized soft-tissue medical implants produced |
| US20100030340A1 (en) * | 1998-06-30 | 2010-02-04 | Wolfinbarger Jr Lloyd | Plasticized Grafts and Methods of Making and Using Same |
| AT407047B (de) * | 1998-08-03 | 2000-11-27 | Pfaller Walter Dr | Zellkulturvorrichtung |
| WO2000029553A1 (en) | 1998-11-19 | 2000-05-25 | Organogenesis Inc. | Bioengineered tissue constructs and methods for producing and using them |
| US6030789A (en) * | 1999-03-10 | 2000-02-29 | The Gillette Company | Human conjunctival epithelial cell lines with an extended life span |
| US6287340B1 (en) * | 1999-05-14 | 2001-09-11 | Trustees Of Tufts College | Bioengineered anterior cruciate ligament |
| US20040023907A1 (en) * | 2000-05-31 | 2004-02-05 | Christoph Dieterich | Infection model |
| US7172859B2 (en) * | 2000-07-14 | 2007-02-06 | Transform Pharmaceuticals, Inc. | System and method for optimizing tissue barrier transfer of compounds |
| US6852526B2 (en) * | 2000-07-14 | 2005-02-08 | Transform Pharmaceuticals, Inc. | Transdermal assay with magnetic clamp |
| AU7788701A (en) * | 2000-07-14 | 2002-01-30 | Transform Pharmaceuticals Inc | System and method for optimizing tissue barrier transfer of compounds |
| US20080182293A1 (en) * | 2000-07-14 | 2008-07-31 | Transform Pharmaceuticals, Inc. | Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples |
| AU2002341867A1 (en) * | 2001-09-27 | 2003-04-07 | The Wistar Institute | Methods and compositions for monitoring cell migration and identifying clinically relevant cytotoxic t lymphocyte activity |
| WO2003041568A2 (en) * | 2001-11-15 | 2003-05-22 | University Of Medicine & Dentistry Of New Jersey | A three-dimensional matrix for producing living tissue equivalents |
| US20040219659A1 (en) * | 2002-04-22 | 2004-11-04 | Altman Gregory H. | Multi-dimensional strain bioreactor |
| AUPS242702A0 (en) * | 2002-05-21 | 2002-06-13 | Colltech Australia Limited | Improved method for the extraction and purification of collagen |
| US7229820B2 (en) | 2002-06-13 | 2007-06-12 | Wilson Wolf Manufacturing Corporation | Apparatus and method for culturing and preserving tissue constructs |
| AU2003242967A1 (en) * | 2002-07-12 | 2004-02-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method and device for inducing biological processes by micro-organs |
| US6908760B2 (en) * | 2002-10-28 | 2005-06-21 | Transform Pharmaceuticals, Inc. | Raised surface assay plate |
| US7449307B2 (en) * | 2002-10-28 | 2008-11-11 | Transform Pharmaceuticals, Inc. | Raised surface assay plate |
| US20040185430A1 (en) * | 2002-12-20 | 2004-09-23 | Marc Andre Lefebvre | Process for evaluating the cosmetic or dermatological activity of a product and use of plant material |
| US9744043B2 (en) | 2007-07-16 | 2017-08-29 | Lifenet Health | Crafting of cartilage |
| CN101918532B (zh) * | 2007-08-22 | 2016-03-30 | 普罗柏欧贞股份公司 | 用于体外测试免疫原性和免疫功能的培养系统和方法 |
| US9535056B2 (en) * | 2008-01-10 | 2017-01-03 | L'oreal | Immune system modeling devices and methods |
| DK3404093T3 (da) | 2008-07-16 | 2020-03-16 | Childrens Medical Center | Anordning og fremgangsmåde til overvågning af celleadfærd |
| WO2011126980A1 (en) * | 2010-04-05 | 2011-10-13 | Millipore Corporation | Polymeric membranes with human skin like permeability properties and uses thereof |
| EP2681306B1 (de) | 2011-02-28 | 2019-01-09 | President and Fellows of Harvard College | Zellkultursystem |
| US9725687B2 (en) | 2011-12-09 | 2017-08-08 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
| EP2725094A1 (de) * | 2012-10-29 | 2014-04-30 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Epithelgewebemodell |
| WO2015013332A1 (en) | 2013-07-22 | 2015-01-29 | President And Fellows Of Harvard College | Microfluidic cartridge assembly |
| GB2583047B (en) | 2013-12-20 | 2021-03-24 | Harvard College | Organomimetic devices and methods of use and manufacturing thereof |
| US11119093B2 (en) | 2013-12-20 | 2021-09-14 | President And Fellows Of Harvard College | Low shear microfluidic devices and methods of use and manufacturing thereof |
| GB2546424A (en) | 2014-07-14 | 2017-07-19 | Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
| WO2017019542A1 (en) | 2015-07-24 | 2017-02-02 | President And Fellows Of Harvard College | Radial microfluidic devices and methods of use |
| US12104174B2 (en) | 2016-09-13 | 2024-10-01 | President And Fellows Of Harvard College | Methods relating to intestinal organ-on-a-chip |
| CN112980690B (zh) * | 2019-12-17 | 2022-10-21 | 华东数字医学工程研究院 | Pdx模型孵育装置和抗肿瘤药物筛选方法 |
| AU2022302088A1 (en) * | 2021-07-01 | 2024-01-18 | Ambient Biosciences, Inc. | Device for vitrifying and delivering vitrified bioactive agents |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4539716A (en) * | 1981-03-19 | 1985-09-10 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
| US4546500A (en) * | 1981-05-08 | 1985-10-15 | Massachusetts Institute Of Technology | Fabrication of living blood vessels and glandular tissues |
| WO1983002953A1 (en) * | 1982-02-19 | 1983-09-01 | Endotronics Inc | Process and apparatus for controlling patterns of chemicals stimuli administration to biological tissue |
| US4629686A (en) * | 1982-02-19 | 1986-12-16 | Endotronics, Inc. | Apparatus for delivering a controlled dosage of a chemical substance |
| US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
| US4485097A (en) * | 1982-05-26 | 1984-11-27 | Massachusetts Institute Of Technology | Bone-equivalent and method for preparation thereof |
| US4734372A (en) * | 1983-02-04 | 1988-03-29 | Brown University Research Foundation | Cell culturing methods and apparatus |
| US4559299A (en) * | 1983-02-04 | 1985-12-17 | Brown University Research Foundation Inc. | Cytotoxicity assays in cell culturing devices |
| JPS6110136A (ja) * | 1984-06-25 | 1986-01-17 | Fumio Itatsu | 油圧機器の圧力調整装置 |
| JPS6134832A (ja) * | 1984-07-26 | 1986-02-19 | Hitachi Ltd | 大口径イオン源 |
| JPS6133593A (ja) * | 1984-07-26 | 1986-02-17 | 株式会社東芝 | 防犯装置 |
| US4604346A (en) * | 1984-10-09 | 1986-08-05 | Massachusetts Institute Of Technology | Skin-equivalent prepared by the use of punch biopsy |
| US4760020A (en) * | 1985-05-03 | 1988-07-26 | Eye Research Institute Of Retina Foundation | Method for testing biocompatibility |
-
1987
- 1987-03-31 US US07/032,848 patent/US4835102A/en not_active Expired - Lifetime
-
1988
- 1988-03-01 IL IL85599A patent/IL85599A/xx not_active IP Right Cessation
- 1988-03-30 CA CA000562955A patent/CA1305913C/en not_active Expired - Lifetime
- 1988-03-31 ES ES88302953T patent/ES2106010T3/es not_active Expired - Lifetime
- 1988-03-31 JP JP63076647A patent/JP2767803B2/ja not_active Expired - Lifetime
- 1988-03-31 DE DE3855991T patent/DE3855991T2/de not_active Expired - Fee Related
- 1988-03-31 AT AT88302953T patent/ATE156915T1/de not_active IP Right Cessation
- 1988-03-31 EP EP88302953A patent/EP0295762B1/de not_active Expired - Lifetime
-
1997
- 1997-10-15 GR GR970402692T patent/GR3025046T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3855991T2 (de) | 1998-01-22 |
| IL85599A0 (en) | 1988-08-31 |
| EP0295762A3 (de) | 1990-07-04 |
| US4835102A (en) | 1989-05-30 |
| CA1305913C (en) | 1992-08-04 |
| EP0295762A2 (de) | 1988-12-21 |
| ES2106010T3 (es) | 1997-11-01 |
| DE3855991D1 (de) | 1997-09-18 |
| JP2767803B2 (ja) | 1998-06-18 |
| EP0295762B1 (de) | 1997-08-13 |
| GR3025046T3 (en) | 1998-01-30 |
| IL85599A (en) | 1991-11-21 |
| JPS63296699A (ja) | 1988-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |