ES2108255T3 - Sistema de disolvente destinado para ser incluido en capsulas. - Google Patents

Sistema de disolvente destinado para ser incluido en capsulas.

Info

Publication number
ES2108255T3
ES2108255T3 ES93901341T ES93901341T ES2108255T3 ES 2108255 T3 ES2108255 T3 ES 2108255T3 ES 93901341 T ES93901341 T ES 93901341T ES 93901341 T ES93901341 T ES 93901341T ES 2108255 T3 ES2108255 T3 ES 2108255T3
Authority
ES
Spain
Prior art keywords
solvent system
capsules
system intended
molecula
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93901341T
Other languages
English (en)
Inventor
Hirokazu Makino
Ichiro Hakamada
Osamu Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Application granted granted Critical
Publication of ES2108255T3 publication Critical patent/ES2108255T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PARA AUMENTAR LA SOLUBILIDAD DE MEDICINAS ACIDAS, UN SISTEMA DISOLVENTE DE GRAN CONCENTRACION, PARA ENCAPSULAR, COMPRENDE: A) DEL 10 AL 80% POR PESO DE MEDICINA ACIDA; B) DE 0''1 A 1''0 IONES HIDROXILADOS POR MOLECULA GRAMO PARA UNA MOLECULA EQUIVALENTE DE DICHA MEDICINA; Y C) DE 1 A 20% POR PESO DE AGUA INCLUIDA EN ESTER ACIDO GRASO DE SORBITAN DE POLIOXIETILENO COMO EL DISOLVENTE.
ES93901341T 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas. Expired - Lifetime ES2108255T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03337138A JP3121080B2 (ja) 1991-12-19 1991-12-19 カプセル封入用溶液

Publications (1)

Publication Number Publication Date
ES2108255T3 true ES2108255T3 (es) 1997-12-16

Family

ID=18305803

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93901341T Expired - Lifetime ES2108255T3 (es) 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas.

Country Status (9)

Country Link
US (1) US5912011A (es)
EP (1) EP0572627B1 (es)
JP (1) JP3121080B2 (es)
AU (1) AU3278393A (es)
CA (1) CA2103793C (es)
DE (1) DE69222031T2 (es)
ES (1) ES2108255T3 (es)
WO (1) WO1993011753A1 (es)
ZA (1) ZA929854B (es)

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US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
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US20070053868A1 (en) * 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents
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US20080269334A1 (en) * 2005-09-19 2008-10-30 Albemarle Corporation Highly Concentrated Pourable Aqueous Solutions Of Potassium Ibuprofen, Their Preparation And Their Use
US20070086952A1 (en) * 2005-09-29 2007-04-19 Biodel, Inc. Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
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WO2009069139A1 (en) * 2007-11-28 2009-06-04 Alkem Laboratories Ltd. Dosage form providing an ibuprofen-containing liquid fill
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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
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EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
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US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
AU2010259943C1 (en) 2009-06-12 2016-03-03 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
MX353285B (es) 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
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WO2014060855A1 (en) * 2012-10-16 2014-04-24 Wockhardt Limited Pharmaceutical compositions of diclofenac or salts thereof
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
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CN107951857B (zh) * 2017-11-29 2019-12-24 浙江安宝药业有限公司 布洛芬软胶囊
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Also Published As

Publication number Publication date
US5912011A (en) 1999-06-15
JPH05310566A (ja) 1993-11-22
DE69222031D1 (de) 1997-10-09
AU3278393A (en) 1993-07-19
EP0572627B1 (en) 1997-09-03
ZA929854B (en) 1994-01-13
CA2103793A1 (en) 1993-06-20
EP0572627A1 (en) 1993-12-08
DE69222031T2 (de) 1998-03-26
CA2103793C (en) 1999-12-07
WO1993011753A1 (en) 1993-06-24
JP3121080B2 (ja) 2000-12-25

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