ES2108255T3 - Sistema de disolvente destinado para ser incluido en capsulas. - Google Patents

Sistema de disolvente destinado para ser incluido en capsulas.

Info

Publication number
ES2108255T3
ES2108255T3 ES93901341T ES93901341T ES2108255T3 ES 2108255 T3 ES2108255 T3 ES 2108255T3 ES 93901341 T ES93901341 T ES 93901341T ES 93901341 T ES93901341 T ES 93901341T ES 2108255 T3 ES2108255 T3 ES 2108255T3
Authority
ES
Spain
Prior art keywords
solvent system
capsules
system intended
molecula
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93901341T
Other languages
English (en)
Inventor
Hirokazu Makino
Ichiro Hakamada
Osamu Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Application granted granted Critical
Publication of ES2108255T3 publication Critical patent/ES2108255T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PARA AUMENTAR LA SOLUBILIDAD DE MEDICINAS ACIDAS, UN SISTEMA DISOLVENTE DE GRAN CONCENTRACION, PARA ENCAPSULAR, COMPRENDE: A) DEL 10 AL 80% POR PESO DE MEDICINA ACIDA; B) DE 0''1 A 1''0 IONES HIDROXILADOS POR MOLECULA GRAMO PARA UNA MOLECULA EQUIVALENTE DE DICHA MEDICINA; Y C) DE 1 A 20% POR PESO DE AGUA INCLUIDA EN ESTER ACIDO GRASO DE SORBITAN DE POLIOXIETILENO COMO EL DISOLVENTE.
ES93901341T 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas. Expired - Lifetime ES2108255T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03337138A JP3121080B2 (ja) 1991-12-19 1991-12-19 カプセル封入用溶液

Publications (1)

Publication Number Publication Date
ES2108255T3 true ES2108255T3 (es) 1997-12-16

Family

ID=18305803

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93901341T Expired - Lifetime ES2108255T3 (es) 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas.

Country Status (9)

Country Link
US (1) US5912011A (es)
EP (1) EP0572627B1 (es)
JP (1) JP3121080B2 (es)
AU (1) AU3278393A (es)
CA (1) CA2103793C (es)
DE (1) DE69222031T2 (es)
ES (1) ES2108255T3 (es)
WO (1) WO1993011753A1 (es)
ZA (1) ZA929854B (es)

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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
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CN102099017A (zh) * 2008-07-21 2011-06-15 雅宝公司 高含量布洛芬钠颗粒、其制备及其在制备非泡腾固体剂型中的用途
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
RU2509555C2 (ru) 2009-06-12 2014-03-20 Маннкайнд Корпорейшн Микрочастицы дикетопиперазина с определенными удельными площадями поверхности
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KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
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Also Published As

Publication number Publication date
CA2103793A1 (en) 1993-06-20
US5912011A (en) 1999-06-15
EP0572627B1 (en) 1997-09-03
JPH05310566A (ja) 1993-11-22
DE69222031D1 (de) 1997-10-09
CA2103793C (en) 1999-12-07
EP0572627A1 (en) 1993-12-08
DE69222031T2 (de) 1998-03-26
AU3278393A (en) 1993-07-19
ZA929854B (en) 1994-01-13
JP3121080B2 (ja) 2000-12-25
WO1993011753A1 (en) 1993-06-24

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