ES2108255T3 - Sistema de disolvente destinado para ser incluido en capsulas. - Google Patents

Sistema de disolvente destinado para ser incluido en capsulas.

Info

Publication number
ES2108255T3
ES2108255T3 ES93901341T ES93901341T ES2108255T3 ES 2108255 T3 ES2108255 T3 ES 2108255T3 ES 93901341 T ES93901341 T ES 93901341T ES 93901341 T ES93901341 T ES 93901341T ES 2108255 T3 ES2108255 T3 ES 2108255T3
Authority
ES
Spain
Prior art keywords
solvent system
capsules
system intended
molecula
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93901341T
Other languages
English (en)
Inventor
Hirokazu Makino
Ichiro Hakamada
Osamu Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Application granted granted Critical
Publication of ES2108255T3 publication Critical patent/ES2108255T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PARA AUMENTAR LA SOLUBILIDAD DE MEDICINAS ACIDAS, UN SISTEMA DISOLVENTE DE GRAN CONCENTRACION, PARA ENCAPSULAR, COMPRENDE: A) DEL 10 AL 80% POR PESO DE MEDICINA ACIDA; B) DE 0''1 A 1''0 IONES HIDROXILADOS POR MOLECULA GRAMO PARA UNA MOLECULA EQUIVALENTE DE DICHA MEDICINA; Y C) DE 1 A 20% POR PESO DE AGUA INCLUIDA EN ESTER ACIDO GRASO DE SORBITAN DE POLIOXIETILENO COMO EL DISOLVENTE.
ES93901341T 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas. Expired - Lifetime ES2108255T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03337138A JP3121080B2 (ja) 1991-12-19 1991-12-19 カプセル封入用溶液

Publications (1)

Publication Number Publication Date
ES2108255T3 true ES2108255T3 (es) 1997-12-16

Family

ID=18305803

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93901341T Expired - Lifetime ES2108255T3 (es) 1991-12-19 1992-12-18 Sistema de disolvente destinado para ser incluido en capsulas.

Country Status (9)

Country Link
US (1) US5912011A (es)
EP (1) EP0572627B1 (es)
JP (1) JP3121080B2 (es)
AU (1) AU3278393A (es)
CA (1) CA2103793C (es)
DE (1) DE69222031T2 (es)
ES (1) ES2108255T3 (es)
WO (1) WO1993011753A1 (es)
ZA (1) ZA929854B (es)

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US9006175B2 (en) * 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
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US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
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US7279457B2 (en) * 2004-03-12 2007-10-09 Biodel, Inc. Rapid acting drug delivery compositions
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US20060088590A1 (en) * 2004-10-22 2006-04-27 Banner Pharmacaps, Inc. Non-blooming gelatin and non-gelatin formulations
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CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
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WO2007041481A1 (en) * 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
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US20080075767A1 (en) * 2006-06-30 2008-03-27 Jin Xiao P Ibuprofen-containing liquid filled hard capsules
WO2008124522A2 (en) * 2007-04-04 2008-10-16 Biodel, Inc. Amylin formulations
WO2009069139A1 (en) * 2007-11-28 2009-06-04 Alkem Laboratories Ltd. Dosage form providing an ibuprofen-containing liquid fill
EP2234644B1 (en) * 2008-01-04 2013-07-31 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
US9629806B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
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BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
US20150250750A1 (en) * 2012-10-16 2015-09-10 Wockhardt Limited Pharmaceutical compostions of diclofenac or salts thereof
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AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016140933A2 (en) * 2015-03-02 2016-09-09 Bionpharma Healthcare Llc Immediate release soluble ibuprofen compositions
CN107951857B (zh) * 2017-11-29 2019-12-24 浙江安宝药业有限公司 布洛芬软胶囊
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GB2595300B (en) * 2020-05-21 2024-03-27 Reckitt Benckiser Health Ltd Novel Formulation
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Also Published As

Publication number Publication date
JP3121080B2 (ja) 2000-12-25
CA2103793A1 (en) 1993-06-20
WO1993011753A1 (en) 1993-06-24
EP0572627A1 (en) 1993-12-08
DE69222031D1 (de) 1997-10-09
DE69222031T2 (de) 1998-03-26
AU3278393A (en) 1993-07-19
US5912011A (en) 1999-06-15
JPH05310566A (ja) 1993-11-22
EP0572627B1 (en) 1997-09-03
ZA929854B (en) 1994-01-13
CA2103793C (en) 1999-12-07

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