ES2133709T3 - Transcripcion de adn bicatenario inducida por analogo de acido nucleico. - Google Patents

Transcripcion de adn bicatenario inducida por analogo de acido nucleico.

Info

Publication number
ES2133709T3
ES2133709T3 ES95901410T ES95901410T ES2133709T3 ES 2133709 T3 ES2133709 T3 ES 2133709T3 ES 95901410 T ES95901410 T ES 95901410T ES 95901410 T ES95901410 T ES 95901410T ES 2133709 T3 ES2133709 T3 ES 2133709T3
Authority
ES
Spain
Prior art keywords
initiation site
dna
template
nucleic acid
acid analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95901410T
Other languages
English (en)
Inventor
Rolf Henrik Berg
Michael Egholm
Peter Eigil Nielsen
Ole Buchardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2133709T3 publication Critical patent/ES2133709T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

EL ARN ES TRANSCRITO DESDE UNA PLANTILLA DE DOBLE CADENA DE ADN FORMANDO UN COMPLEJO POR HIBRIDACION A UNA PLANTILLA, EN UN LADO DE INICIACION DE LA TRANSCRIPCION DESEADA O MAS ACIDOS OLIGONUCLEICOS ANALOGOS DEL TIPO APN, CAPAZ DE FORMAR UN LADO DE INICIACION DE TRANSCRIPCION CON EL ADN Y LA EXPOSICION DEL COMPLEJO A LA ACCION DE UN ADN DEPENDIENTE DE POLIMERASA ARN, EN PRESENCIA DE TRIFOSFATOS NUCLEOSIDOS. TRANSCRIPCIONES DE IGUAL LONGITUD, SE PUEDEN OBTENER POR UBICACION DE UN BLOQUE A UN FLUJO DESCENDENTE DE TRANSCRIPCION DESDE EL LADO DE INICIACION O POR EL CORTE DE LA PLANTILLA TAL COMO EN UNA POSICION SELECCIONADA. EL LADO DE INICIACION ES FORMADO POR EL DESPLAZAMIENTO DE LAS CADENAS DE ADN LOCALMENTE POR LA HIBRIDACION DE APN.
ES95901410T 1993-11-25 1994-11-22 Transcripcion de adn bicatenario inducida por analogo de acido nucleico. Expired - Lifetime ES2133709T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9324245A GB2284209A (en) 1993-11-25 1993-11-25 Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template

Publications (1)

Publication Number Publication Date
ES2133709T3 true ES2133709T3 (es) 1999-09-16

Family

ID=10745684

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95901410T Expired - Lifetime ES2133709T3 (es) 1993-11-25 1994-11-22 Transcripcion de adn bicatenario inducida por analogo de acido nucleico.

Country Status (10)

Country Link
US (1) US5837459A (es)
EP (1) EP0730664B1 (es)
JP (1) JP3143475B2 (es)
AT (1) ATE176932T1 (es)
CA (1) CA2176746C (es)
DE (1) DE69416692T2 (es)
DK (1) DK0730664T3 (es)
ES (1) ES2133709T3 (es)
GB (1) GB2284209A (es)
WO (1) WO1995014789A1 (es)

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US6617422B1 (en) 1997-05-23 2003-09-09 Peter Nielsen Peptide nucleic acid monomers and oligomers
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US6989270B1 (en) 1997-10-17 2006-01-24 Mayo Foundation For Medical Education And Research Using polyamide nucleic acid oligomers to engender a biological response
AU3671099A (en) 1998-04-29 1999-11-16 Trustees Of Boston University Methods and compositions pertaining to pd-loops
US7981599B1 (en) 1998-07-31 2011-07-19 Boston Probes, Inc. Non-nucleic acid probes, probe sets, methods and kits pertaining to the detection of individual human chromosomes X, Y, 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 16, 17, 18 and 20 as 13/21 as a pair
US20040014644A1 (en) * 2000-03-14 2004-01-22 Vladimir Efimov Oligonucleotide analogues and methods of use for modulating gene expression
US6962906B2 (en) * 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
AU2001247414A1 (en) 2000-03-14 2001-09-24 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
DE60138916D1 (de) 2000-09-26 2009-07-16 Boston Probes Inc Sonden, sondensätzen,verfahren und kits zur nachweis, identifizierung und/oder die zählung von bakterien
WO2002031166A2 (en) * 2000-10-13 2002-04-18 Crosslink Genetics Corporation Artificial transcriptional factors and methods of use
AU2002246676A1 (en) * 2000-12-15 2002-07-30 Boston Probes, Inc. Methods for determining organisms
DE60216468T2 (de) * 2001-03-09 2007-09-27 Boston Probes, Inc., Bedford Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
EP1417333B1 (en) 2001-05-18 2011-10-05 Boston Probes, Inc. Pna probes, probe sets, methods and kits pertaining to the detection of candida
WO2003027328A2 (en) 2001-09-24 2003-04-03 Boston Probes, Inc. Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid
US7045319B2 (en) * 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
JP2005520554A (ja) * 2002-03-21 2005-07-14 ボストン プローブス，インコーポレイテッド ＢａｃｉｌｌｕｓＡｎｔｈｒａｃｉｓの検出に関するＰＮＡオリゴマー、オリゴマーセット、方法およびキット
US20030211509A1 (en) * 2002-03-26 2003-11-13 Wiley Steven R. TNF-delta ligand and uses thereof
WO2003100076A2 (en) * 2002-05-17 2003-12-04 Applera Corporation Pna probes, probe sets, method and kits pertaining to the determination of listeria
EP1575990B1 (en) 2002-09-08 2009-11-18 Applera Corporation Solid phase bound PNA-dimers and their synthesis
US7413857B2 (en) * 2002-11-21 2008-08-19 Epicentre Technologies Methods for using riboprimers for strand displacement replication of target sequences
US20040259132A1 (en) * 2002-11-22 2004-12-23 Henrik Stender Peptide nucleic acid probes for analysis of pseudomonas (sensu stricto)
US20050214796A1 (en) * 2003-10-29 2005-09-29 Hanna Michelle M Compositions, methods and detection technologies for reiterative oligonucleotide synthesis
US7306916B2 (en) * 2004-05-04 2007-12-11 Dako Denmark A/S Methods for detecting chromosome aberrations
CA2590399A1 (en) * 2004-12-06 2007-04-19 Bioveris Corporation Methods and compositions for detecting bacillus anthracis
US7700287B2 (en) * 2005-01-28 2010-04-20 Life Technologies Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template
WO2006130872A2 (en) 2005-06-02 2006-12-07 Advandx, Inc. Peptide nucleic acid probes for analysis of microorganisms
ATE501277T1 (de) 2005-07-01 2011-03-15 Dako Denmark As Monomere und polymere linker zur konjugierung von biologischen molekülen und anderen stoffen
US20080241838A1 (en) * 2006-12-29 2008-10-02 Applera Corporation, Applied Biosystems Group Methods and systems for detecting nucleic acids
JP2010514450A (ja) * 2006-12-29 2010-05-06 アプライド バイオシステムズ インコーポレイテッド 核酸検出方法及びシステム
EP2167537A2 (en) 2007-07-03 2010-03-31 Dako Denmark A/S Compiled methods for analysing and sorting samples
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ES2601237T3 (es) 2009-12-02 2017-02-14 Dako Denmark A/S Composiciones y métodos para realizar hibridaciones sin desnaturalización
WO2011087789A2 (en) 2009-12-22 2011-07-21 Becton, Dickinson And Company Methods for the detection of microorganisms
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US11118226B2 (en) 2011-10-21 2021-09-14 Agilent Technologies, Inc. Hybridization compositions and methods
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LT6214B (lt) 2013-10-07 2015-08-25 Uab "Bioseka" Priešprasminiai oligonukleotidai aterosklerozės ir kardiovaskulinių infekcijų prevencijai
JP6640079B2 (ja) 2013-10-16 2020-02-05 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 小容積の粒子を調製するためのデバイス及び方法
KR102626448B1 (ko) 2015-02-24 2024-01-19 더 유니버시티 오브 브리티시 콜롬비아 연속 흐름 미세유체 시스템
ES3047482T3 (en) 2016-01-06 2025-12-03 Univ British Columbia Bifurcating mixers and methods of their use and manufacture
US20210284998A1 (en) 2016-10-03 2021-09-16 Precision Nanosystems Inc. Compositions for Transfecting Resistant Cell Types

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DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
GB9211979D0 (en) * 1992-06-05 1992-07-15 Buchard Ole Uses of nucleic acid analogues

Also Published As

Publication number Publication date
GB9324245D0 (en) 1994-01-12
GB2284209A (en) 1995-05-31
WO1995014789A1 (en) 1995-06-01
DE69416692D1 (de) 1999-04-01
CA2176746A1 (en) 1995-06-01
JPH09503393A (ja) 1997-04-08
DK0730664T3 (da) 1999-09-27
CA2176746C (en) 2000-08-08
DE69416692T2 (de) 1999-08-05
EP0730664A1 (en) 1996-09-11
GB2284209A8 (en) 1995-09-25
US5837459A (en) 1998-11-17
ATE176932T1 (de) 1999-03-15
JP3143475B2 (ja) 2001-03-07
EP0730664B1 (en) 1999-02-24

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