ES2149378T3 - Procedimiento para la sulfonilacion, sulfenilacion y fosforilacion de depsipeptidos ciclicos. - Google Patents

Procedimiento para la sulfonilacion, sulfenilacion y fosforilacion de depsipeptidos ciclicos.

Info

Publication number
ES2149378T3
ES2149378T3 ES95935902T ES95935902T ES2149378T3 ES 2149378 T3 ES2149378 T3 ES 2149378T3 ES 95935902 T ES95935902 T ES 95935902T ES 95935902 T ES95935902 T ES 95935902T ES 2149378 T3 ES2149378 T3 ES 2149378T3
Authority
ES
Spain
Prior art keywords
phosphorilation
procedure
sulphonilation
sulphenilation
cyclic depsipeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95935902T
Other languages
English (en)
Inventor
Jurgen Scherkenbeck
Andrew Plant
Peter Jeschke
Achim Harder
Norbert Mencke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2149378T3 publication Critical patent/ES2149378T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL OBJETO DE LA PRESENTE INVENCION ES UN PROCEDIMIENTO PARA LA SULFONILACION, SULFENILACION, TIOCIANIZACION Y FOSFORILACION AROMATICAS DE DEPEPSIPEPTIDOS CICLICOS CON 6 A 24 ATOMOS EN EL CICLO, QUE ESTAN COMPUESTOS POR ACIDOS {AL}-HIDROXICARBOXILICOS Y {AL}-AMINOACIDOS, Y CONTIENEN AL MENOS UN RADICAL FENILICO, CARACTERIZADO PORQUE ESTOS DEPSIPEPTIDOS CICLICOS SE HACEN REACCIONAR CON REACTIVOS DE SULFONILACION, SULFENILACION, TIOCIANIZACION O FOSFORILACION, OPCIONALMENTE EN PRESENCIA DE CATALIZADORES, ADYUVANTES Y/O DILUYENTES; TAMBIEN LOS NUEVOS COMPUESTOS OBTENIDOS Y SU UTILIZACION COMO AGENTES CONTRA ENDOPARASITOS.
ES95935902T 1994-10-18 1995-10-05 Procedimiento para la sulfonilacion, sulfenilacion y fosforilacion de depsipeptidos ciclicos. Expired - Lifetime ES2149378T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437198A DE4437198A1 (de) 1994-10-18 1994-10-18 Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden

Publications (1)

Publication Number Publication Date
ES2149378T3 true ES2149378T3 (es) 2000-11-01

Family

ID=6531064

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95935902T Expired - Lifetime ES2149378T3 (es) 1994-10-18 1995-10-05 Procedimiento para la sulfonilacion, sulfenilacion y fosforilacion de depsipeptidos ciclicos.

Country Status (17)

Country Link
US (1) US5874530A (es)
EP (1) EP0787141B1 (es)
JP (1) JPH10511341A (es)
AT (1) ATE195952T1 (es)
AU (1) AU698898B2 (es)
BR (1) BR9509377A (es)
CA (1) CA2202751A1 (es)
CZ (1) CZ112397A3 (es)
DE (2) DE4437198A1 (es)
DK (1) DK0787141T3 (es)
ES (1) ES2149378T3 (es)
FI (1) FI971610A0 (es)
HU (1) HU218569B (es)
NZ (1) NZ294843A (es)
PL (1) PL319649A1 (es)
SK (1) SK48697A3 (es)
WO (1) WO1996011945A2 (es)

Families Citing this family (182)

* Cited by examiner, † Cited by third party
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DE4437198A1 (de) * 1994-10-18 1996-04-25 Bayer Ag Verfahren zur Sulfonylierung, Sulfenylierung und Phosphorylierung von cyclischen Depsipeptiden
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
DE19713626A1 (de) * 1997-04-02 1998-10-08 Bayer Ag Neue Thiodepsipeptide zur Bekämpfung von Endoparasiten und ein einfaches Verfahren zu ihrer Herstellung
US6136838A (en) * 1998-03-19 2000-10-24 Merck & Co., Inc. Sulfurpentafluorophenylpyrazoles for controlling ectoparasitic infestations
DE10031044A1 (de) * 2000-06-26 2002-01-03 Bayer Ag Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere
WO2005090313A1 (en) 2004-03-18 2005-09-29 Pfizer Limited N-(1-arylpyrazol-4l)sulfonamides and their use as parasiticides
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
DE102008022520A1 (de) 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
DE102008030764A1 (de) 2008-06-28 2009-12-31 Bayer Animal Health Gmbh Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden
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FI971610A7 (fi) 1997-04-16
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DK0787141T3 (da) 2000-12-11
ATE195952T1 (de) 2000-09-15
WO1996011945A2 (de) 1996-04-25
DE4437198A1 (de) 1996-04-25
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NZ294843A (en) 1998-11-25
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AU3803895A (en) 1996-05-06
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CZ112397A3 (en) 1997-07-16
EP0787141A2 (de) 1997-08-06
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WO1996011945A3 (de) 1996-07-25
FI971610A0 (fi) 1997-04-16
EP0787141B1 (de) 2000-08-30
AU698898B2 (en) 1998-11-12
MX9702771A (es) 1997-07-31
HU218569B (hu) 2000-10-28

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