ES2149783T3 - Derivados del imidazolil-fenol, medicamentos que los contienen, asi como procedimiento para su preparacion. - Google Patents

Derivados del imidazolil-fenol, medicamentos que los contienen, asi como procedimiento para su preparacion.

Info

Publication number
ES2149783T3
ES2149783T3 ES93101999T ES93101999T ES2149783T3 ES 2149783 T3 ES2149783 T3 ES 2149783T3 ES 93101999 T ES93101999 T ES 93101999T ES 93101999 T ES93101999 T ES 93101999T ES 2149783 T3 ES2149783 T3 ES 2149783T3
Authority
ES
Spain
Prior art keywords
contain
preparation
phenol
derivatives
imidazolil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93101999T
Other languages
English (en)
Inventor
Joachim Dr Ammann
Michael Dr Haurand
Cornelia Dr Geist
Werner Dr Englberger
Oswald Dr Zimmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Chemie Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH, Chemie Gruenenthal GmbH filed Critical Gruenenthal GmbH
Application granted granted Critical
Publication of ES2149783T3 publication Critical patent/ES2149783T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE AL DERIVADO 3 ZOL 1 IL) FENOL DE LA FORMULA GENERAL I EN DONDE R1 SIGNIFICA NH2 O CH3, R2 ES H O CH3, X ES O O S, Y ES H, OH O OCH3 Y Z CH = CH -. O O S, Y/O SUS SALES, MEDICAMENTOS, QUE CONTIENEN TALES COMPUESTOS, ASI COMO UN PROCESO PARA LA FABRICACION DE ESTOS COMPUESTOS Y MEDICAMENTOS.
ES93101999T 1992-02-17 1993-02-09 Derivados del imidazolil-fenol, medicamentos que los contienen, asi como procedimiento para su preparacion. Expired - Lifetime ES2149783T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4204686A DE4204686A1 (de) 1992-02-17 1992-02-17 Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln

Publications (1)

Publication Number Publication Date
ES2149783T3 true ES2149783T3 (es) 2000-11-16

Family

ID=6451889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93101999T Expired - Lifetime ES2149783T3 (es) 1992-02-17 1993-02-09 Derivados del imidazolil-fenol, medicamentos que los contienen, asi como procedimiento para su preparacion.

Country Status (9)

Country Link
US (1) US5356921A (es)
EP (1) EP0557787B1 (es)
JP (1) JPH069571A (es)
AT (1) ATE193283T1 (es)
DE (2) DE4204686A1 (es)
DK (1) DK0557787T3 (es)
ES (1) ES2149783T3 (es)
GR (1) GR3033678T3 (es)
PT (1) PT557787E (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3322885B2 (ja) * 1995-02-02 2002-09-09 日研化学株式会社 Ｎ−ヒドロキシウレア誘導体
US6291482B1 (en) 1997-11-11 2001-09-18 Nikken Chemicals Co., Ltd N-hydroxyurea derivative and pharmaceutical composition containing the same
EP1389611B1 (en) 2001-04-26 2012-06-27 Taisho Pharmaceutical Co., Ltd 20-hydroxyeicosatetraenoic acid production inhibitors
SG175390A1 (en) 2009-04-29 2011-12-29 Amarin Corp Plc Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
WO2016149126A1 (en) 2015-03-13 2016-09-22 The Board Of Trustees Of The Leland Stanford Junior University Ltb4 inhibition to prevent and treat human lymphedema
WO2020039088A2 (en) * 2018-08-24 2020-02-27 Xeniopro GmbH Novel compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
DK471479A (da) * 1978-12-13 1980-06-14 Pfizer Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
JPS58150566A (ja) * 1982-03-03 1983-09-07 Yoshitomi Pharmaceut Ind Ltd 新規イミダゾ−ル誘導体
DE3424944A1 (de) * 1984-07-06 1986-02-06 Hoechst Ag, 6230 Frankfurt Neue imidazolyverbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3686733T2 (de) * 1985-03-16 1993-02-11 Wellcome Found Aryl-derivate.
GB2185741B (en) * 1986-01-27 1989-10-25 American Home Prod Heterocyclic sulphonamides
US5026729A (en) * 1987-02-10 1991-06-25 Abbott Laboratories Lipoxygenase inhibiting compounds
ES2053609T3 (es) * 1987-04-24 1994-08-01 Abbott Lab Derivados de urea inhibidores de lipoxigenasa.
GB8820185D0 (en) * 1988-08-25 1988-09-28 Wellcome Found New medical use
AU624896B2 (en) * 1989-02-03 1992-06-25 Wellcome Foundation Limited, The Anti-inflammatory aryl derivatives
WO1990012008A1 (en) * 1989-03-30 1990-10-18 Abbott Laboratories Urea based lipoxygenase inhibiting compounds
US5220059A (en) * 1990-04-19 1993-06-15 Abbott Laboratories Lipoxygenase-inhibiting compounds derived from non-steroidal antiinflammatory carboxylic acids

Also Published As

Publication number Publication date
JPH069571A (ja) 1994-01-18
GR3033678T3 (en) 2000-10-31
EP0557787B1 (de) 2000-05-24
US5356921A (en) 1994-10-18
DE59310044D1 (de) 2000-06-29
EP0557787A1 (de) 1993-09-01
ATE193283T1 (de) 2000-06-15
DK0557787T3 (da) 2000-10-30
PT557787E (pt) 2000-10-31
DE4204686A1 (de) 1993-08-19
HK1010106A1 (en) 1999-06-11

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