ES2156856T3 - Sintesis de acidos grasos de plantas. - Google Patents

Sintesis de acidos grasos de plantas.

Info

Publication number
ES2156856T3
ES2156856T3 ES91918831T ES91918831T ES2156856T3 ES 2156856 T3 ES2156856 T3 ES 2156856T3 ES 91918831 T ES91918831 T ES 91918831T ES 91918831 T ES91918831 T ES 91918831T ES 2156856 T3 ES2156856 T3 ES 2156856T3
Authority
ES
Spain
Prior art keywords
plants
synthesis
fatty acids
bps
isomero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91918831T
Other languages
English (en)
Inventor
Vic C Knauf
Gregory A Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Calgene LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calgene LLC filed Critical Calgene LLC
Application granted granted Critical
Publication of ES2156856T3 publication Critical patent/ES2156856T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19002—Acyl-[acyl-carrier-protein] desaturase (1.14.19.2)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE 4, 4''-BISFENOL S EN DONDE AL ACIDO SULFURICO SE LE HACE REACCIONAR CON UN EXCESO DE FENOL AL TIEMPO QUE SE EXTRAE AGUA; LA PUREZA DEL PRODUCTO SE MEJORA RESPECTO AL ISOMERO DE 2, 4''-BPS A BASE DE AÑADIR TOLUENO A LA MEZCLA DEL PRODUCTO INICIAL PARA RECICLA PARA ISOMERIZAR EL 2, 4''-BPS A 4, 4''-BPS.
ES91918831T 1990-08-15 1991-08-15 Sintesis de acidos grasos de plantas. Expired - Lifetime ES2156856T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56849390A 1990-08-15 1990-08-15
US07/721,761 US5475099A (en) 1990-08-15 1991-06-26 Plant fatty acid synthases

Publications (1)

Publication Number Publication Date
ES2156856T3 true ES2156856T3 (es) 2001-08-01

Family

ID=27074805

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91918831T Expired - Lifetime ES2156856T3 (es) 1990-08-15 1991-08-15 Sintesis de acidos grasos de plantas.

Country Status (10)

Country Link
US (2) US5475099A (es)
EP (1) EP0495096B1 (es)
JP (1) JPH06500234A (es)
AT (1) ATE200106T1 (es)
CA (1) CA2087977A1 (es)
DE (1) DE69132566T2 (es)
DK (1) DK0495096T3 (es)
ES (1) ES2156856T3 (es)
GR (1) GR3036036T3 (es)
WO (1) WO1992003564A1 (es)

Families Citing this family (51)

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US6483008B1 (en) * 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
DE69231875T2 (de) * 1991-04-09 2001-10-04 Unilever N.V., Rotterdam Pflanzen-promoter involviert in der kontrolle der lipid-biosynthese in samen
CA2123495A1 (en) * 1991-11-15 1993-05-27 Anthony J. Kinney B-ketoacyl-acp synthetase ii genes from plants
US5679881A (en) * 1991-11-20 1997-10-21 Calgene, Inc. Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism
CA2148358A1 (en) * 1992-11-02 1994-05-11 Vic C. Knauf Plant fatty acid synthases
US5650303A (en) * 1993-02-26 1997-07-22 Calgene, Inc. Geminivirus-based gene expression system
US6066721A (en) 1995-07-06 2000-05-23 Stanford University Method to produce novel polyketides
US6500960B1 (en) 1995-07-06 2002-12-31 Stanford University (Board Of Trustees Of The Leland Stanford Junior University) Method to produce novel polyketides
US6828475B1 (en) 1994-06-23 2004-12-07 Calgene Llc Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-CoA metabolism
US6310194B1 (en) 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
CA2203754C (en) * 1994-10-26 2010-01-12 Douglas W. James, Jr. Fae1 genes and their uses
IL122859A0 (en) * 1995-07-06 1998-08-16 Univ Leland Stanford Junior Cell-free synthesis of polyketides
US5965793A (en) 1995-09-20 1999-10-12 Monsanto Company, Inc. Strong early seed-specific gene regulatory region
AU4858897A (en) * 1996-10-31 1998-05-22 Ravinder Kumar Jain Flax promoters for manipulating gene expression
US6200788B1 (en) 1997-01-24 2001-03-13 Kirin Beer Kabushiki Kaisha β-ketoacyl-ACP synthetase II enzymes and genes coding for same
EP1624066A3 (en) * 1997-04-11 2007-03-28 Calgene LLC Plant fatty acid synthases and use in improved methods for production of medium-chain fatty acids
AR013633A1 (es) 1997-04-11 2001-01-10 Calgene Llc METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA.
US6323395B1 (en) * 1997-12-24 2001-11-27 Dow Agrosciences Llc Nucleotide sequences of maize and soybean β-Ketoacyl-Acyl Carrier Protein Synthase II and their use in the regulation of fatty acid content of oil
CA2359801A1 (en) 1999-02-09 2000-08-17 Rajesh S. Gokhale Methods to mediate polyketide synthase module effectiveness
US7001748B2 (en) * 1999-02-09 2006-02-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of making polyketides using hybrid polyketide synthases
DE19926456A1 (de) * 1999-06-10 2000-12-14 Norddeutsche Pflanzenzucht Han Verfahren zur Erhöhung des Fettsäuregehalts in Pflanzensamen
CN1378602A (zh) * 1999-08-26 2002-11-06 卡尔根尼有限公司 含修饰的多不饱和脂肪酸的植物
US7067722B2 (en) * 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7531718B2 (en) * 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7183376B2 (en) * 2000-06-23 2007-02-27 Maxygen, Inc. Variant B7 co-stimulatory molecules
CA2411828A1 (en) 2000-06-23 2002-01-03 Maxygen, Inc. Novel co-stimulatory molecules
US20050154189A1 (en) * 2000-06-23 2005-07-14 Maxygen Inc Novel co-stimulatory molecules
ES2317910T3 (es) * 2000-07-06 2009-05-01 Georgetown University Formas (fijas) estables e proteinas de capside l1 virales, proteinas de fusion y sus utilizaciones.
WO2002008403A2 (en) * 2000-07-25 2002-01-31 Calgene Llc Nucleic acid sequences encoding beta-ketoacyl-acp synthase and uses thereof
CA2340998C (en) 2001-03-21 2012-01-03 Saskatchewan Wheat Pool Selective modification of plant fatty acids
GB0107510D0 (en) * 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
MY146503A (en) * 2001-08-13 2012-08-15 Malaysian Palm Oil Board Method and compositions for the production of transgenic plants
CA2474163C (en) * 2002-01-30 2012-04-17 Basf Plant Science Gmbh Novel elongase gene and method for producing polyunsaturated fatty acids
AU2003213757A1 (en) * 2002-03-04 2003-09-22 Brown University Research Foundation Methods to mediate polyketide synthase module effectiveness
US7166771B2 (en) * 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
US7566813B2 (en) * 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
AR039113A1 (es) * 2002-03-21 2005-02-09 Monsanto Technology Llc Construcciones de acidos nucleicos y metodos para producir composiciones de aceites de semillas alteradas
AU2003251579B2 (en) * 2002-06-21 2008-04-03 Monsanto Technology Llc Intron double stranded RNA constructs and uses thereof
US7273966B2 (en) * 2002-12-19 2007-09-25 Monsanto Technology Llc Elevation of fatty acid synthase levels in plants
US20090049572A1 (en) * 2002-12-19 2009-02-19 Voelker Toni A Elevation of oil levels in plants
WO2004056848A2 (en) * 2002-12-19 2004-07-08 Monsanto Technology, Llc Elevation of oil levels in brassica plants
BRPI0404234A (pt) * 2004-01-21 2005-11-01 Malaysian Palm Oil Board Enzima recombinante e usos da mesma
PT2308977E (pt) * 2004-04-30 2013-05-13 Dow Agrosciences Llc Novo gene de resistência a herbicida
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
AR075549A1 (es) * 2008-09-29 2011-04-20 Monsanto Technology Llc Evento transgenico de soja mon87705 y metodos para detectar el mismo
US20150223493A1 (en) * 2014-02-10 2015-08-13 Lee Tech Llc System for and method of converting agricultural waste to animal feed and other valuable raw materials
US11427839B2 (en) 2014-08-29 2022-08-30 Lee Tech Llc Yeast stage tank incorporated fermentation system and method
US11680278B2 (en) 2014-08-29 2023-06-20 Lee Tech Llc Yeast stage tank incorporated fermentation system and method
US11166478B2 (en) 2016-06-20 2021-11-09 Lee Tech Llc Method of making animal feeds from whole stillage
WO2022159719A1 (en) 2021-01-22 2022-07-28 Lee Tech Llc System and method for improving the corn wet mill and dry mill process
US12065513B2 (en) 2022-06-17 2024-08-20 Lee Tech Llc System for and method of producing pure starch slurry and alcohol by using a process combining wet corn milling and a dry corn milling processes

Family Cites Families (8)

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US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
NZ221258A (en) * 1986-07-31 1990-05-28 Calgene Inc Acyl carrier protein - dna sequence and synthesis
NZ221259A (en) * 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
US5147792A (en) * 1986-10-09 1992-09-15 Calgene, Inc. Method of shifting the fatty acid distribution in plastids towards shorter-chained species by using thioesterase II and acyl carrier protein
US4888282A (en) * 1987-06-04 1989-12-19 The United States Of America As Represented By The Secretary Of Agriculture Synthetic gene for acyl carrier protein
US5057419A (en) * 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
US5087563A (en) * 1990-03-09 1992-02-11 The United States Of America, As Represented By The Secretary Of Agriculture Acyl carrier protein-I/protein-A gene fusion, products and methods
JPH07501701A (ja) * 1991-12-04 1995-02-23 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 植物由来の脂肪酸不飽和化酵素遺伝子

Also Published As

Publication number Publication date
EP0495096A1 (en) 1992-07-22
DE69132566T2 (de) 2001-09-13
ATE200106T1 (de) 2001-04-15
JPH06500234A (ja) 1994-01-13
WO1992003564A1 (en) 1992-03-05
US5510255A (en) 1996-04-23
DE69132566D1 (de) 2001-05-03
EP0495096B1 (en) 2001-03-28
DK0495096T3 (da) 2001-07-02
EP0495096A4 (en) 1993-06-09
GR3036036T3 (en) 2001-09-28
CA2087977A1 (en) 1992-02-16
US5475099A (en) 1995-12-12

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