ES2156904T3 - Composicion farmaceutica. - Google Patents

Composicion farmaceutica.

Info

Publication number
ES2156904T3
ES2156904T3 ES94928043T ES94928043T ES2156904T3 ES 2156904 T3 ES2156904 T3 ES 2156904T3 ES 94928043 T ES94928043 T ES 94928043T ES 94928043 T ES94928043 T ES 94928043T ES 2156904 T3 ES2156904 T3 ES 2156904T3
Authority
ES
Spain
Prior art keywords
pharmaceutically acceptable
mixture
pharmaceutical composition
acceptable organic
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94928043T
Other languages
English (en)
Inventor
Laman A Al-Razzak
Kennan C Marsh
Richard A Pyter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of ES2156904T3 publication Critical patent/ES2156904T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

UNA COMPOSICION FARMACEUTICA SOLIDA QUE CONSTA DE UN ABSORBENTE FARMACEUTICAMENTE ACEPTABLE O UNA MEZCLA DE ABSORBENTES FARMACEUTICAMENTE ACEPTABLES, A LA QUE SE ABSORBE UNA MEZCLA DE (1) UN SOLVENTE ORGANICO FARMACEUTICAMENTE ACEPTABLE O UNA MEZCLA DE DICHOS SOLVENTES, (2) UN COMPUESTO INHIBIDOR DE PROTEASA VIH Y (3) UNO O MAS ACIDOS FARMACEUTICAMENTE ACEPTABLES. LA COMPOSICION SOLIDA PUEDE ENCAPSULARSE OPCIONALMENTE EN UNA CAPSULA DE GELATINA DURA.
ES94928043T 1993-10-01 1994-09-09 Composicion farmaceutica. Expired - Lifetime ES2156904T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13040993A 1993-10-01 1993-10-01
US26727394A 1994-06-28 1994-06-28
US08/297,004 US5559158A (en) 1993-10-01 1994-08-31 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
ES2156904T3 true ES2156904T3 (es) 2001-08-01

Family

ID=27384007

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94928043T Expired - Lifetime ES2156904T3 (es) 1993-10-01 1994-09-09 Composicion farmaceutica.

Country Status (14)

Country Link
US (2) US5559158A (es)
EP (1) EP0721330B1 (es)
JP (1) JPH09503501A (es)
KR (1) KR100330442B1 (es)
AT (1) ATE200023T1 (es)
AU (1) AU685509B2 (es)
CA (1) CA2167413A1 (es)
DE (1) DE69426984T2 (es)
DK (1) DK0721330T3 (es)
ES (1) ES2156904T3 (es)
GR (1) GR3036091T3 (es)
IL (1) IL110915A (es)
PT (1) PT721330E (es)
WO (1) WO1995009614A1 (es)

Families Citing this family (82)

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US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
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US6232333B1 (en) 1996-11-21 2001-05-15 Abbott Laboratories Pharmaceutical composition
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
WO1998035666A1 (en) * 1997-02-13 1998-08-20 Nanosystems Llc Formulations of nanoparticle naproxen tablets
AU8145198A (en) * 1997-06-16 1999-01-04 Vertex Pharmaceuticals Incorporated Methods of increasing the bioavailability of stable crystal polymorphs of a compound
MY145265A (en) * 1998-07-20 2012-01-13 Abbott Lab Amorphous ritonavir
US6894171B1 (en) 1998-07-20 2005-05-17 Abbott Laboratories Polymorph of a pharmaceutical
WO2000074677A2 (en) * 1999-06-04 2000-12-14 Abbott Laboratories Improved pharmaceutical formulations
US7141593B1 (en) 1999-06-04 2006-11-28 Abbott Laboratories Pharmaceutical formulations
IT1313624B1 (it) * 1999-09-21 2002-09-09 Archimica Spa Ora Clariant Lif Procedimento per la sintesi del ritonavir
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WO2001034119A2 (en) * 1999-11-12 2001-05-17 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
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US6911214B2 (en) 2000-09-05 2005-06-28 Abbott Laboratories Flavoring systems for pharmaceutical compositions and methods of making such compositions
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US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
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CA2541634A1 (en) 2003-10-10 2005-04-28 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
EP1944042A1 (en) 2003-10-27 2008-07-16 Vertex Pharmceuticals Incorporated Combinations for HCV treatment
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ES2373685T3 (es) 2005-07-29 2012-02-07 Tibotec Pharmaceuticals Inhibidores macrocíclicos del virus de la hepatitis c.
JO2768B1 (en) 2005-07-29 2014-03-15 تيبوتيك فارماسيوتيكالز ليمتد Large cyclic inhibitors of hepatitis C virus
TWI412535B (zh) 2005-07-29 2013-10-21 Tibotec Pharm Ltd Ｃ型肝炎病毒之大環抑制劑（五）
DK1919899T3 (da) 2005-07-29 2011-08-01 Tibotec Pharm Ltd Makrocykliske inhibitorer af hepatitis C virus
PE20070210A1 (es) 2005-07-29 2007-04-16 Tibotec Pharm Ltd Compuestos macrociclicos como inhibidores del virus de hepatitis c
PL1919898T3 (pl) 2005-07-29 2011-06-30 Tibotec Pharm Ltd Makrocykliczne inhibitory wirusa zapalenia wątroby typu C
PE20070211A1 (es) 2005-07-29 2007-05-12 Medivir Ab Compuestos macrociclicos como inhibidores del virus de hepatitis c
CA2617679A1 (en) * 2005-08-02 2007-02-08 Steve Lyons Inhibitors of serine proteases
US7964624B1 (en) 2005-08-26 2011-06-21 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
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WO2007109080A2 (en) * 2006-03-16 2007-09-27 Vertex Pharmaceuticals Incorporated Deuterated hepatitis c protease inhibitors
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WO2008106058A2 (en) 2007-02-27 2008-09-04 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
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WO2009032198A1 (en) * 2007-08-30 2009-03-12 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical compositions comprising the same
CN103479584A (zh) * 2008-05-02 2014-01-01 吉里德科学公司 固体载体颗粒在改善药物制剂加工性中的应用
KR101016899B1 (ko) 2008-06-03 2011-02-22 삼성에스디아이 주식회사 배터리 팩 및 그 충전 방법
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EP2396028A2 (en) 2009-02-12 2011-12-21 Vertex Pharmceuticals Incorporated Hcv combination therapies comprising pegylated interferon, ribavirin and telaprevir
US8945735B2 (en) 2009-02-23 2015-02-03 Samsung Sdi Co., Ltd. Built-in charge circuit for secondary battery and secondary battery with the built-in charge circuit
MY169734A (en) 2009-04-25 2019-05-14 Hoffmann La Roche Methods for improving pharmacokinetics
CN102844030A (zh) 2010-01-29 2012-12-26 沃泰克斯药物股份有限公司 用于治疗丙型肝炎病毒感染的疗法
JP6158702B2 (ja) * 2010-04-09 2017-07-05 ブリストル−マイヤーズ・スクイブ・ホールディングス・アイルランドＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｈｏｌｄｉｎｇｓ Ｉｒｅｌａｎｄ ｐＨの影響を改善したアタザナビル硫酸塩製剤
WO2012109646A1 (en) 2011-02-11 2012-08-16 Vertex Pharmaceuticals Incorporated Treatment of hcv in hiv infection patients
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UA117375C2 (uk) 2013-09-04 2018-07-25 Медівір Аб Інгібітори полімерази hcv
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Also Published As

Publication number Publication date
US5559158A (en) 1996-09-24
GR3036091T3 (en) 2001-09-28
KR100330442B1 (ko) 2002-08-21
PT721330E (pt) 2001-09-28
CA2167413A1 (en) 1995-04-13
ATE200023T1 (de) 2001-04-15
KR960703567A (ko) 1996-08-31
DK0721330T3 (da) 2001-06-25
AU685509B2 (en) 1998-01-22
IL110915A0 (en) 1994-11-28
EP0721330B1 (en) 2001-03-28
US5610193A (en) 1997-03-11
WO1995009614A1 (en) 1995-04-13
EP0721330A1 (en) 1996-07-17
DE69426984D1 (de) 2001-05-03
JPH09503501A (ja) 1997-04-08
AU7722994A (en) 1995-05-01
DE69426984T2 (de) 2001-11-22
IL110915A (en) 1999-12-22

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