ES2157466T3 - Procedimiento de preparacion de compuestos con grupo beta-hidroxi-delta-lactona analogos de la (+) compactina y de la (+) mevinolina. - Google Patents
Procedimiento de preparacion de compuestos con grupo beta-hidroxi-delta-lactona analogos de la (+) compactina y de la (+) mevinolina.Info
- Publication number
- ES2157466T3 ES2157466T3 ES96938297T ES96938297T ES2157466T3 ES 2157466 T3 ES2157466 T3 ES 2157466T3 ES 96938297 T ES96938297 T ES 96938297T ES 96938297 T ES96938297 T ES 96938297T ES 2157466 T3 ES2157466 T3 ES 2157466T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- delta
- beta
- mevinolina
- compactine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A UN NUEVO PROCEDIMIENTO PARA PREPARAR COMPUESTO DE GRUPO {BE} GOS DE LA (+) COMPACTINA Y DE LA (+) MEVINOLINA. EL PROCEDIMIENTO DE PREPARACION DE ESTOS PRODUCTOS EMPLEA NUEVOS INTERMEDIOS DE REACCION A LOS QUE TAMBIEN SE REFIERE LA INVENCION ASI COMO A LOS PROCEDIMIENTOS DE PREPARACION RESPECTIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9514093A FR2741620B1 (fr) | 1995-11-28 | 1995-11-28 | Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2157466T3 true ES2157466T3 (es) | 2001-08-16 |
Family
ID=9484968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96938297T Expired - Lifetime ES2157466T3 (es) | 1995-11-28 | 1996-11-12 | Procedimiento de preparacion de compuestos con grupo beta-hidroxi-delta-lactona analogos de la (+) compactina y de la (+) mevinolina. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0805800B1 (es) |
| JP (1) | JP3119663B2 (es) |
| AT (1) | ATE199709T1 (es) |
| DE (1) | DE69612086T2 (es) |
| ES (1) | ES2157466T3 (es) |
| FR (1) | FR2741620B1 (es) |
| WO (1) | WO1997019917A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0623580B2 (ja) * | 1986-11-19 | 1994-03-30 | 株式会社三ッ葉電機製作所 | スタータのクラッチのアウタとインナ間の開放端を閉塞するカバ−の固定構造及び固定方法 |
| CA2284525A1 (en) * | 1997-04-16 | 1998-10-22 | The University Of New Mexico | Inhibitors of cholesterol esterase |
| EP1323715B1 (en) * | 1997-04-16 | 2004-06-30 | The University of New Mexico | Inhibitors of cholesterol esterase |
| GB9903472D0 (en) * | 1999-02-17 | 1999-04-07 | Zeneca Ltd | Chemical process |
| GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
| NL1015744C2 (nl) * | 2000-07-19 | 2002-01-22 | Dsm Nv | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
| AR034772A1 (es) | 2001-07-13 | 2004-03-17 | Astrazeneca Uk Ltd | Preparacion de los compuestos de aminopirimidina |
| EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
| US20060234337A1 (en) * | 2002-04-12 | 2006-10-19 | Akira Arisawa | Expression system for actinomycete-origin cytochrome p-450 in escherichia coli |
| EP1375493A1 (en) | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
| GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
| ATE448209T1 (de) | 2002-12-16 | 2009-11-15 | Astrazeneca Uk Ltd | Verfahren zur herstellung von pyrimidinverbindungen |
| GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
| UY28501A1 (es) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
| GB0322552D0 (en) | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
| GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
| GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| US8455640B2 (en) | 2006-05-03 | 2013-06-04 | Msn Laboratories Limited | Process for statins and its pharmaceutically acceptable salts thereof |
| US8404841B2 (en) | 2006-10-09 | 2013-03-26 | Msn Laboratories Limited | Process for the preparation of statins and their pharmaceutically acceptable salts thereof |
| EP2387561A4 (en) | 2009-01-19 | 2012-07-25 | Msn Lab Ltd | IMPROVED METHOD FOR THE PRODUCTION OF HIGH-PURITY (3R, 5S) -7- [2-CYCLOPROPYL-4- (4-FLUORPHENYL) CHINOLIN-3-YL] -3,5-DIHYDROXY-6 (E) -HEPTENIC ACID AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF |
| WO2011086584A2 (en) | 2010-01-18 | 2011-07-21 | Msn Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
-
1995
- 1995-11-28 FR FR9514093A patent/FR2741620B1/fr not_active Expired - Fee Related
-
1996
- 1996-11-12 AT AT96938297T patent/ATE199709T1/de not_active IP Right Cessation
- 1996-11-12 WO PCT/FR1996/001782 patent/WO1997019917A1/fr not_active Ceased
- 1996-11-12 JP JP09520222A patent/JP3119663B2/ja not_active Expired - Fee Related
- 1996-11-12 DE DE69612086T patent/DE69612086T2/de not_active Expired - Fee Related
- 1996-11-12 EP EP96938297A patent/EP0805800B1/fr not_active Expired - Lifetime
- 1996-11-12 ES ES96938297T patent/ES2157466T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0805800B1 (fr) | 2001-03-14 |
| WO1997019917A1 (fr) | 1997-06-05 |
| FR2741620A1 (fr) | 1997-05-30 |
| EP0805800A1 (fr) | 1997-11-12 |
| ATE199709T1 (de) | 2001-03-15 |
| DE69612086T2 (de) | 2001-06-21 |
| JPH10504845A (ja) | 1998-05-12 |
| FR2741620B1 (fr) | 1997-12-26 |
| DE69612086D1 (de) | 2001-04-19 |
| JP3119663B2 (ja) | 2000-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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