ES2162186T3 - Nuevos derivados del acido 4-fenil-2-(piperacinil/perhidrodiacepinil/aminoalquil)carbonilmetil)-1,4-dihidropiridin-3,5-dicarboxilico como antagonistas de receptores de bradiquinina. - Google Patents
Nuevos derivados del acido 4-fenil-2-(piperacinil/perhidrodiacepinil/aminoalquil)carbonilmetil)-1,4-dihidropiridin-3,5-dicarboxilico como antagonistas de receptores de bradiquinina.Info
- Publication number
- ES2162186T3 ES2162186T3 ES97200232T ES97200232T ES2162186T3 ES 2162186 T3 ES2162186 T3 ES 2162186T3 ES 97200232 T ES97200232 T ES 97200232T ES 97200232 T ES97200232 T ES 97200232T ES 2162186 T3 ES2162186 T3 ES 2162186T3
- Authority
- ES
- Spain
- Prior art keywords
- breast
- sub
- sup
- rent
- bradiquinine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB9600131 | 1996-02-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2162186T3 true ES2162186T3 (es) | 2001-12-16 |
Family
ID=11004405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97200232T Expired - Lifetime ES2162186T3 (es) | 1996-02-19 | 1997-01-29 | Nuevos derivados del acido 4-fenil-2-(piperacinil/perhidrodiacepinil/aminoalquil)carbonilmetil)-1,4-dihidropiridin-3,5-dicarboxilico como antagonistas de receptores de bradiquinina. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5861402A (de) |
| EP (1) | EP0790239B1 (de) |
| JP (1) | JPH09227521A (de) |
| AT (1) | ATE205478T1 (de) |
| CA (1) | CA2197739C (de) |
| DE (1) | DE69706575T2 (de) |
| DK (1) | DK0790239T3 (de) |
| ES (1) | ES2162186T3 (de) |
| GR (1) | GR3037064T3 (de) |
| MX (1) | MX9701245A (de) |
| PT (1) | PT790239E (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TNSN97037A1 (fr) * | 1996-02-19 | 2005-03-15 | Pfizer | Derives de 1,4 -dihydropyridine, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| ATE257479T1 (de) * | 1999-12-10 | 2004-01-15 | Pfizer | 5-ring heteroarylsubstituierte 1,4- dihydropyridine als bradykinin antagonisten |
| EP1110962A1 (de) * | 1999-12-10 | 2001-06-27 | Pfizer Inc. | Verfahren zur herstellung von 1,4-dihydropyridine verbindungen |
| US6653313B2 (en) | 2000-08-10 | 2003-11-25 | Warner-Lambert Company Llc | 1,4-dihydropyridine compounds as bradykinin antagonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2658183A1 (de) * | 1976-12-22 | 1978-07-06 | Bayer Ag | In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US5162497A (en) * | 1987-09-24 | 1992-11-10 | The Administrators Of The Tulane Educational Fund | Bradykinin analogs with non-peptide bond |
| US5610142A (en) * | 1992-10-08 | 1997-03-11 | Scios Inc. | Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids |
| WO1996006083A1 (en) * | 1994-08-24 | 1996-02-29 | Pfizer Pharmaceuticals Inc. | 2-(piperazinyl-1-carbonylmethyl)-1,4-dihydropyridines as bradykinin antagonists |
-
1996
- 1996-02-19 MX MX9701245A patent/MX9701245A/es unknown
-
1997
- 1997-01-29 AT AT97200232T patent/ATE205478T1/de not_active IP Right Cessation
- 1997-01-29 ES ES97200232T patent/ES2162186T3/es not_active Expired - Lifetime
- 1997-01-29 PT PT97200232T patent/PT790239E/pt unknown
- 1997-01-29 EP EP97200232A patent/EP0790239B1/de not_active Expired - Lifetime
- 1997-01-29 DE DE69706575T patent/DE69706575T2/de not_active Expired - Fee Related
- 1997-01-29 DK DK97200232T patent/DK0790239T3/da active
- 1997-01-31 US US08/797,681 patent/US5861402A/en not_active Expired - Fee Related
- 1997-02-13 JP JP9042869A patent/JPH09227521A/ja active Pending
- 1997-02-17 CA CA002197739A patent/CA2197739C/en not_active Expired - Fee Related
-
2001
- 2001-10-30 GR GR20010401936T patent/GR3037064T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE205478T1 (de) | 2001-09-15 |
| DE69706575D1 (de) | 2001-10-18 |
| DE69706575T2 (de) | 2002-04-18 |
| GR3037064T3 (en) | 2002-01-31 |
| CA2197739A1 (en) | 1997-08-20 |
| US5861402A (en) | 1999-01-19 |
| EP0790239B1 (de) | 2001-09-12 |
| EP0790239A1 (de) | 1997-08-20 |
| PT790239E (pt) | 2002-01-30 |
| DK0790239T3 (da) | 2001-11-19 |
| JPH09227521A (ja) | 1997-09-02 |
| MX9701245A (es) | 1998-04-30 |
| CA2197739C (en) | 2000-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Grant refused |
Effective date: 20010516 |
|
| FG2A | Definitive protection |
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