ES2163000T3 - Suministro topico de farmacos al tracto gastrointestinal inferior. - Google Patents

Suministro topico de farmacos al tracto gastrointestinal inferior.

Info

Publication number
ES2163000T3
ES2163000T3 ES96903489T ES96903489T ES2163000T3 ES 2163000 T3 ES2163000 T3 ES 2163000T3 ES 96903489 T ES96903489 T ES 96903489T ES 96903489 T ES96903489 T ES 96903489T ES 2163000 T3 ES2163000 T3 ES 2163000T3
Authority
ES
Spain
Prior art keywords
pharmacos
gastrointestinal tract
lower gastrointestinal
colon
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96903489T
Other languages
English (en)
Inventor
David L Berliner
Sergio Nacht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heron Therapeutics LLC
Original Assignee
Advanced Polymer Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Polymer Systems Inc filed Critical Advanced Polymer Systems Inc
Application granted granted Critical
Publication of ES2163000T3 publication Critical patent/ES2163000T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

TRATAMIENTO DE DETERMINADAS ENFERMEDADES DEL COLON MEDIANTE LA INGESTION ORAL EN UNA FORMA DE DOSIFICACION ADECUADA QUE CONTIENE UNA COMPOSICION QUE CONTIENE UNA VARIEDAD DE CUENTAS DE POLIMERO RIGIDAS RETICULADAS, DEFINIENDO CADA UNA RED DE POROS INTERNOS SUSTANCIALMENTE NO COLAPSABLE, Y UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE UN AGENTE O FARMACO ACTIVO EN DICHA RED DE POROS. LA FORMA DE DOSIFICACION SE TRATA CON UN POLISACARIDO TAL COMO PECTINA, QUE ES ESPECIFICAMENTE ATACADA POR LA FLORA BACTERIANA PARA PERMITIR LA LIBERACION DEL FARMACO EN EL COLON.
ES96903489T 1996-01-16 1996-01-16 Suministro topico de farmacos al tracto gastrointestinal inferior. Expired - Lifetime ES2163000T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/000512 WO1997025980A1 (en) 1996-01-16 1996-01-16 Topical delivery of drugs to the lower gastrointestinal tract

Publications (1)

Publication Number Publication Date
ES2163000T3 true ES2163000T3 (es) 2002-01-16

Family

ID=22254620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96903489T Expired - Lifetime ES2163000T3 (es) 1996-01-16 1996-01-16 Suministro topico de farmacos al tracto gastrointestinal inferior.

Country Status (9)

Country Link
EP (1) EP0876142B1 (es)
KR (1) KR19990077278A (es)
AT (1) ATE206043T1 (es)
AU (1) AU710109B2 (es)
CA (1) CA2244421A1 (es)
DE (1) DE69615583T2 (es)
DK (1) DK0876142T3 (es)
ES (1) ES2163000T3 (es)
WO (1) WO1997025980A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972933A (en) * 1998-01-08 1999-10-26 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating microbial infections
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
IL124957A0 (en) * 1998-06-16 1999-01-26 Univ Ben Gurion Active ingredient delivery systems and devices based on porous matrices
IT1301947B1 (it) * 1998-07-28 2000-07-20 Chiesi Farma Spa Formulazioni farmaceutiche di beclometasone dipropionato per iltrattamento di malattie infiammatorie croniche della mucosa
US6962717B1 (en) 1999-01-29 2005-11-08 Disphar International B.V. Pharmaceutical compositions
US20020004502A1 (en) 2000-01-05 2002-01-10 Redmond H. Paul Treatment of inflammatory bowel disease
EP1315777B1 (en) 2000-09-06 2007-10-31 AP Pharma, Inc. Degradable polyacetal polymers
US6524606B1 (en) 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
US7045589B2 (en) 2002-11-15 2006-05-16 A.P. Pharma, Inc. Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
EP2079456B1 (en) 2007-04-04 2012-12-05 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
CZ302789B6 (cs) 2009-11-25 2011-11-09 Zentiva, K. S. Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva
IT1405012B1 (it) * 2010-08-06 2013-12-16 Sofar Spa Composizioni di beclometasone dipropionato in microsfere gastroresistenti a rilascio modificato e processo per il loro ottenimento
GB201119985D0 (en) 2011-11-19 2012-01-04 Diurnal Ltd Treatment of adrenal insufficiency
GB201202433D0 (en) 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
GB201308933D0 (en) 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD291668A7 (de) * 1986-02-28 1991-07-11 Berlin-Chemie Ag,De Verfahren zur herstellung einer oral anwendbaren gnrh-zubereitung
RU2113221C1 (ru) * 1990-05-04 1998-06-20 Ииссум Рисерч Дивелопмент Компани оф дзе Хебрю Юниверсити оф Иеруcалим Фармацевтическая форма для введения лекарственного средства в ободочную кишку, способ введения лекарственного препарата и способ получения матриц для такой формы
JP3286315B2 (ja) * 1990-06-20 2002-05-27 アドバンスト ポリマー システムズ，インコーポレイティド 可溶性活性物質の調節された放出のための組成物及び方法

Also Published As

Publication number Publication date
DE69615583T2 (de) 2002-07-11
EP0876142A1 (en) 1998-11-11
EP0876142B1 (en) 2001-09-26
CA2244421A1 (en) 1997-07-24
ATE206043T1 (de) 2001-10-15
DE69615583D1 (de) 2001-10-31
KR19990077278A (ko) 1999-10-25
AU710109B2 (en) 1999-09-16
DK0876142T3 (da) 2001-11-19
AU4756496A (en) 1997-08-11
WO1997025980A1 (en) 1997-07-24

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