ES2167548T3 - Anticuerpo monoclonal especifico para el peptido beta-a4. - Google Patents

Anticuerpo monoclonal especifico para el peptido beta-a4.

Info

Publication number
ES2167548T3
ES2167548T3 ES96906616T ES96906616T ES2167548T3 ES 2167548 T3 ES2167548 T3 ES 2167548T3 ES 96906616 T ES96906616 T ES 96906616T ES 96906616 T ES96906616 T ES 96906616T ES 2167548 T3 ES2167548 T3 ES 2167548T3
Authority
ES
Spain
Prior art keywords
peptide
instant invention
monoclonal antibody
beta
specific monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96906616T
Other languages
English (en)
Inventor
Gerhard Konig
Paul Graham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23534218&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2167548(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2167548T3 publication Critical patent/ES2167548T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA UN ANTICUERPO MONOCLONAL QUE ES ESPECIFICO PARA EL PEPTIDO {BE}A4, Y EN PARTICULAR PARA EL EXTREMO C LIBRE DE {BE}A4 "1 RES Y NEUROFIBRILARES. LA PRESENTE INVENCION PROPORCIONA ADICIONALMENTE FRAGMENTOS DE ANTICUERPOS Y ESTRUCTURAS DE LOS MISMOS QUE PRESENTAN LA MISMA CAPACIDAD DE UNION. LA PRESENTE INVENCION PROPORCIONA ASIMISMO METODOS DE DIAGNOSTICO, DE SELECCION Y TERAPEUTICOS PARA EL TRATAMIENTO DE FORMAS UNICAS DEL PEPTIDO {BE}A4, UTILIZANDO LOS ANTICUERPOS DE LA PRESENTE INVENCION.
ES96906616T 1995-02-14 1996-02-14 Anticuerpo monoclonal especifico para el peptido beta-a4. Expired - Lifetime ES2167548T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/388,463 US5786180A (en) 1995-02-14 1995-02-14 Monoclonal antibody 369.2B specific for β A4 peptide

Publications (1)

Publication Number Publication Date
ES2167548T3 true ES2167548T3 (es) 2002-05-16

Family

ID=23534218

Family Applications (3)

Application Number Title Priority Date Filing Date
ES96906616T Expired - Lifetime ES2167548T3 (es) 1995-02-14 1996-02-14 Anticuerpo monoclonal especifico para el peptido beta-a4.
ES07012421T Expired - Lifetime ES2400674T3 (es) 1995-02-14 1996-02-14 Anticuerpo monoclonal específico para péptido BETA A4
ES01114005T Expired - Lifetime ES2288896T5 (es) 1995-02-14 1996-02-14 Anticuerpo monoclonal espec�?fico para péptido beta-a4(1-42).

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES07012421T Expired - Lifetime ES2400674T3 (es) 1995-02-14 1996-02-14 Anticuerpo monoclonal específico para péptido BETA A4
ES01114005T Expired - Lifetime ES2288896T5 (es) 1995-02-14 1996-02-14 Anticuerpo monoclonal espec�?fico para péptido beta-a4(1-42).

Country Status (10)

Country Link
US (3) US5786180A (es)
EP (3) EP0809656B1 (es)
JP (1) JP3115606B2 (es)
AT (2) ATE365750T1 (es)
CA (1) CA2212887C (es)
DE (2) DE69637150T3 (es)
DK (2) DK1160256T4 (es)
ES (3) ES2167548T3 (es)
PT (2) PT1160256E (es)
WO (1) WO1996025435A1 (es)

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Also Published As

Publication number Publication date
EP1160256B2 (en) 2011-11-09
US5786180A (en) 1998-07-28
ATE365750T1 (de) 2007-07-15
EP1160256A3 (en) 2002-11-06
EP1160256B8 (en) 2009-04-01
US5693753A (en) 1997-12-02
DK1160256T3 (da) 2007-10-22
DK0809656T3 (da) 2002-03-18
EP1160256A2 (en) 2001-12-05
EP0809656B1 (en) 2001-12-12
EP1842859B1 (en) 2013-01-09
HK1114105A1 (en) 2008-10-24
EP1842859A2 (en) 2007-10-10
WO1996025435A1 (en) 1996-08-22
DE69617916D1 (de) 2002-01-24
EP1160256B1 (en) 2007-06-27
CA2212887A1 (en) 1996-08-22
EP0809656A1 (en) 1997-12-03
PT809656E (pt) 2002-06-28
DE69637150T3 (de) 2012-03-15
DE69637150T2 (de) 2008-02-28
JP3115606B2 (ja) 2000-12-11
JPH10509736A (ja) 1998-09-22
ES2288896T5 (es) 2012-02-16
ES2400674T3 (es) 2013-04-11
MX9706189A (es) 1997-11-29
DE69617916T2 (de) 2002-05-16
US5679531A (en) 1997-10-21
DE69637150D1 (de) 2007-08-09
ATE210681T1 (de) 2001-12-15
DK1160256T4 (da) 2012-01-09
CA2212887C (en) 2006-10-10
PT1160256E (pt) 2007-10-08
ES2288896T3 (es) 2008-02-01
EP1842859A3 (en) 2007-11-28

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